Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Immune Ingredients & Drug Interactions

by Om Mushroom Superfood

Immune label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Immune against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Immune is a dietary supplement by Om Mushroom Superfood with 4 active ingredients. Its ingredients are commonly taken for immune support, blood sugar support in diabetes, high blood pressure.Based on those ingredients, 260 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Maitake, Powder, Himematsutake, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Immune by Om Mushroom Superfood

Ask about any prescription or over-the-counter medication and we check it for interactions with Immune by Om Mushroom Superfood — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Immune by Om Mushroom Superfood

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Certified Organic Immune Mushroom Powder Blend” is a proprietary blend — the label gives one combined amount (2 Gram(s)) without saying how much of each component you get.

This powder blend contains 4 active mushroom ingredients: maitake, reishi, turkey tail, and himematsutake (agaricus). These are all medicinal mushrooms that have been used traditionally to support immune function, though their effectiveness for specific conditions hasn't been reliably established in clinical research.

The blend also includes myceliated oats as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Supports broad spectrum immune defense.
  • We looked for evidence on: Allergic rhinitis (hay fever), Cancer, Chemotherapy-induced adverse effects, Chemotherapy-induced anemia, Chemotherapy-induced diarrhea, Chemotherapy-induced leukopenia — and 4 related terms.
  • The closest evidence on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-induced anemia, Laryngeal cancer, Chemotherapy-induced diarrhea, Chronic fatigue syndrome (CFS), and more.

The research we have on file doesn't establish reliable effectiveness for either maitake or himematsutake for the conditions listed — these range from allergic rhinitis and osteoporosis to chemotherapy side effects and cardiovascular disease. The evidence is simply too sparse right now to say whether this blend actually works for any particular use.

We have no effectiveness data on file for reishi or turkey tail.

The evidence, ingredient by ingredient Maitake Mushroom Agaricus Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both maitake and himematsutake are generally well tolerated as foods, though supplement safety hasn't been fully studied. The most common side effects are gastrointestinal: a small number of trial participants reported diarrhea, nausea, or stomach pain.

Rarely, allergic reactions have been reported — including rash and itching — which cleared when the product was stopped. Three rare cases of serious liver damage have been reported with agaricus mushroom supplements in women undergoing chemotherapy; we can't predict who might be at risk.

For pregnancy: the safety data for concentrated supplements of maitake and himematsutake is not established enough to recommend them — talk with your doctor or pharmacist for personalized advice. The same applies to breastfeeding.

Side effects, ingredient by ingredient Maitake Mushroom Agaricus Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Maitake Mushroom, Agaricus Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 260 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this, flag it with your doctor or pharmacist if you're on warfarin or any blood thinner — maitake may increase its effect and your bleeding risk. Double-check if you take blood pressure medications or any diabetes drugs, as both mushrooms in this blend may lower blood pressure and blood sugar.

Make sure they're aware so they can monitor you.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take warfarin, blood pressure medications, or diabetes drugs, check with your doctor or pharmacist before starting this product — the mushrooms in it may amplify their effects in ways that matter for your health. If you're planning to take it during pregnancy or while breastfeeding, discuss it with your healthcare provider first because safety data is limited.

Otherwise, it's generally well tolerated, though stomach upset can happen.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immune, straight from the product label.

Brand Om Mushroom Superfood
Barcode (UPC) 892392002744
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 271880
Product type Botanical
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immune by Om Mushroom Superfood, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
4 Gram(s)
Servings per container
50
UPC/BARCODE
892392002744
IngredientAmount% DV
Calories10 Calorie(s)--
Maitake, Powder0 NP--
Reishi, Powder0 NP--
Turkey Tail, Powder0 NP--
Certified Organic Immune Mushroom Powder Blend2 Gram(s)--
Himematsutake, Powder0 NP--

Other ingredients: Oats, Myceliated

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

USDA Organic Non GMO Project Verified nongmoproject.org

Grown in USA

EarthKosher

Formulation

Non GMO Project Verified

Supports broad spectrum defense

Gluten Free

Vegan

Mushroom your microbiome. Functional without anything funky added. No nutrients left behind.

We grow our OM. We grow a diverse range of organic mushroom species at our indoor farm in California and capture the complete nutritional value of the growing cycle. Whole food mushrooms are important because they provide a full spectrum of active compounds to support optimal health. So you can bet your beta glucans they're effective.

Certified Organic by Organic Certifiers

Tested for heavy metals. Complete transparency ID testing.

Formula

Om grown mushroom blend 2,000 mg per serving See Supplement Facts

Certified Organic Mushroom Powder

KETO Keto-Friendly PF Paleo-Friendly

Kosher

The Superfoodie of Superfoods. Mushrooms contain many unique bioactive nutrients that can't be found in plant or animal sources alone. Each serving of Om provides 2,000 mg of Certified Organic Mushroom Powder Blend.

Immune Full bodyguard 4 your immune system. Defend your wellbeing with this powerful combination of 4 organic mushrooms species known for their full spectrum immune benefits. Let Mother Nature protect you with beta glucans, prebiotics, digestive enzymes, fiber and antioxidants to keep your body battle ready. These mushroom are on a mission.

Certified Kosher by Earth Kosher

FDA Statement of Identity

Dietary Supplement

General Statements

What's a beta glucan? Find out at OmMushrooms.com

Packaged with recycled materials

Scan code to learn more Facebook Instagram @OmMushrooms OmMushrooms.com

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Take as directed.

If you have a medical condition, are on medication or are pregnant or nursing, please seek the direction of a qualified health care professional before using.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Scoop. Stir. Ommm your daily ritual. Add 2 grams (approx. 1 tsp) daily to super your smoothie, mushroom your matcha, boost your coffee and nourish your recipes. For optimal support, take 4 grams (approx. 2 tsp) per day.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Immune by Om Mushroom Superfood label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Immune label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Immune by Om Mushroom Superfood

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Certified Organic Immune Mushroom Powder Blend

2 Gram(s) per serving

Other (inactive) ingredients: Oats, Myceliated. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immune by Om Mushroom Superfood Drug Interactions

Want to check YOUR meds against Immune?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
260Drugs
260 Moderate

Ingredients driving the most interactions

Maitake, Powder 260
Himematsutake, Powder 86

Individual Drug Interactions

The ingredients in Immune interact with 260 drugs. Click any drug to see the details.

2 of the 4 ingredients in Immune interact with drugs. Each result below shows which ingredient is responsible. Maitake, Powder Himematsutake, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Immune with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Maitake, Powder3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
Maitake, Powder full monograph & interactions

Himematsutake, Powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
Himematsutake, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Immune, from the product label.

Om Mushroom Superfood

See all Om Mushroom Superfood products
Name
M2 Ingredients
City
Carlsbad
State
CA
ZipCode
92008
Pharmacist Counseling Corner

Immune by Om Mushroom Superfood: Common Questions

Does Immune by Om Mushroom Superfood interact with any medications?
Yes. Based on its ingredients, Immune has a known interaction with 260 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immune contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure or diabetes medication?
You'll want to check with your doctor or pharmacist first. Both maitake and himematsutake can lower blood pressure and blood sugar, so combining them with your medications could push those numbers lower than intended. They may need to adjust your dose or monitor you more closely.
What are the side effects I might see?
Most people tolerate it fine, but stomach upset — diarrhea, nausea, or stomach pain — is the most common issue in trials. Rarely, allergic reactions like rash have been reported. Stop and contact your doctor if you develop severe stomach pain or an unusual rash.
Is this safe during pregnancy or breastfeeding?
We don't have enough safety data to say either way. Talk with your doctor or pharmacist before taking concentrated mushroom supplements while pregnant or nursing — they can help you weigh what's known and what's uncertain for your situation.
What do these mushrooms actually do for me?
They're marketed for immune support and have been used traditionally for that, but the clinical evidence isn't strong enough yet to reliably say they work for any specific condition. The ingredients themselves haven't been proven effective for allergies, cancer support, or the other uses listed.
Does this blend have any fillers?
It contains myceliated oats as an inactive ingredient. The rest is the mushroom powders themselves.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Immune is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immune label
Go deeper

The Full Monographs Behind Immune’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph →
Sources

Sources & How We Checked

Immune's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maitake Mushroom 8 references
  1. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
  2. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
  3. Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
  4. Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
  5. Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
  6. Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
  7. Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
  8. Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed

See these in context on the Maitake Mushroom monograph →

Agaricus Mushroom 5 references
  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

See these in context on the Agaricus Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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