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Dietary supplement

Inosine Ingredients & Drug Interactions

by Ultimate Nutrition Platinum Series

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Inosine is a dietary supplement by Ultimate Nutrition Platinum Series with 1 active ingredient. Its ingredients are commonly taken for athletic performance and energy, multiple sclerosis (raising uric acid), parkinson's disease (raising uric acid).Based on those ingredients, 9 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Inosine by Ultimate Nutrition Platinum Series

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inosine, a naturally occurring compound. It comes in a capsule with gelatin, microcrystalline cellulose, dicalcium phosphate, and magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Inosine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports energy bursts during intense exercise.
  • We looked for evidence on: Athletic performance, Exercise endurance, Athletic recovery, Muscular performance.
  • The closest evidence on file: Inosine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

The evidence we hold doesn't establish that inosine works for any condition in our data—athletic performance, ALS, cancer, diabetic neuropathy, and multiple sclerosis all carry ratings of insufficient reliable evidence. That doesn't mean it doesn't help; it means the science isn't settled yet.

The evidence, ingredient by ingredient Inosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inosine is generally well tolerated by mouth, but it carries a real caution: it raises uric acid levels, which is a problem if you have gout or kidney issues. The most common side effects are high uric acid levels and kidney stones, especially uric acid stones—and the risk climbs if you also take calcium supplements.

Rare but serious effects include high blood pressure and kidney dysfunction. There isn't enough safety information to use inosine during pregnancy, and safety while breastfeeding is unknown; talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Inosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inosine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 9 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antigout drugs—medications to prevent or treat gout—check them against this product first. Inosine can reduce how well they work by raising your uric acid levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Inosine is a single-ingredient supplement with limited evidence for the conditions it's marketed for. If you have gout, kidney problems, or take antigout medications, this isn't the right choice without talking it over with your doctor or pharmacist first.

Even without those conditions, check your exact medications before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inosine, straight from the product label.

Brand Ultimate Nutrition Platinum Series
Barcode (UPC) 099071006202
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 293462
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inosine by Ultimate Nutrition Platinum Series, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
099071006202
IngredientAmount% DV
Inosine1000 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two (2) capsules twice daily, on an empty stomach. with water or fruit juice.

Daily

Precautions

Keep out of reach of children

Do not purchase if seal is broken

Storage

Protect from heat, light and moisture Store at 15-30 degrees C (59-86 degrees F)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Supports production of short energy bursts during intense exercise

FDA Statement of Identity

Inosine Supplement

General Statements

Pre During Post Night

See for yourself

Inosine by Ultimate Nutrition Platinum Series label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Inosine by Ultimate Nutrition Platinum Series

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Inosine

Interacts with
9 drugs
1000 mg per serving Form: Hypoxanthine Riboside

Inosine is a nucleoside (a building block of DNA and RNA) that the body makes on its own and is also sold as a supplement, mostly marketed for athleti...

Inosine monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inosine by Ultimate Nutrition Platinum Series Drug Interactions

Want to check YOUR meds against Inosine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
9Drugs
9 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Inosine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inosine1 drug type · 9 drugs

Antigout Drugs

Inosine might reduce the effects of antigout medications.
Inosine increases uric acid levels in the serum and urine, potentially resulting in hyperuricemia and reducing the effects of medications used for the prevention and treatment of gout.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Inosine, from the product label.

Ultimate Nutrition Platinum Series

See all Ultimate Nutrition Platinum Series products
Name
Ultimate Nutrition, Inc.
Street Address
P.O. Box 643
City
Farmington
State
CT
ZipCode
06034
Web Address
www.ultimatenutrition.com
Pharmacist Counseling Corner

Inosine by Ultimate Nutrition Platinum Series: Common Questions

Does Inosine by Ultimate Nutrition Platinum Series interact with any medications?
Yes. Based on its ingredients, Inosine has a known interaction with 9 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inosine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Inosine if I have gout?
No. Inosine raises uric acid in your blood, which makes gout worse and can undermine your gout medications. Talk with your doctor about whether this product is right for you.
What are the most common side effects?
High uric acid levels and kidney stones—especially uric acid stones. The risk of kidney stones increases if you also take calcium supplements. Rare serious effects include high blood pressure and kidney dysfunction.
Is inosine safe during pregnancy or breastfeeding?
No. There isn't enough safety information for pregnancy, so it's best avoided. Safety while breastfeeding is also unknown. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or breastfeeding.
Does inosine actually work for athletic performance or multiple sclerosis?
The evidence we hold doesn't establish that it does. Athletic performance, multiple sclerosis, ALS, cancer, and diabetic neuropathy all carry ratings of insufficient reliable evidence in our data.
Is inosine safe if I have kidney problems?
No. Inosine can reduce kidney function and cause kidney stones and uric acid crystals in the urine. If you have kidney issues, avoid this product and talk with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inosine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inosine label
Sources

Sources & How We Checked

Inosine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inosine 7 references
  1. Parkinson Study Group SURE-PD Investigators. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol. 2014;71(2):141-50.
  2. Muñoz García D, Midaglia L, Martinez Vilela J, et al. Associated inosine to interferon: results of a clinical trial in multiple sclerosis. Acta Neurol Scand. 2015;131(6):405-10. PubMed
  3. Gonsette RE, Sindic C, D'hooghe MB, et al. Boosting endogenous neuroprotection in multiple sclerosis: The association of inosine and interferon beta in relapsing-remitting Multiple Sclerosis (ASIIMS) trial. Mult Scler. 2010;16(4):455-62.
  4. Markowitz CE, Spitsin S, Zimmerman V, et al. The treatment of multiple sclerosis with inosine. J Altern Complement Med. 2009;15(6):619-25. PubMed
  5. Watanabe H, Hattori T, Kume A, et al. Improved Parkinsons disease motor score in a single-arm open-label trial of febuxostat and inosine. Medicine (Baltimore) 2020;99(35):e21576. PubMed
  6. Parkinson Study Group SURE-PD3 Investigators, Schwarzschild MA, Ascherio A, et al. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA 2021;326(10):926-939.
  7. Walk D, Nicholson K, Locatelli E, et al. Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis. Muscle Nerve 2023;67(5):378-386. PubMed

See these in context on the Inosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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