Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Vanadyl Sulfate Ingredients & Drug Interactions

by Ultimate Nutrition Platinum Series

Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Vanadyl Sulfate is a dietary supplement by Ultimate Nutrition Platinum Series with 1 active ingredient. Its ingredients are commonly taken for blood sugar and diabetes support, athletic performance and muscle building, lowering cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vanadyl Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vanadyl Sulfate by Ultimate Nutrition Platinum Series

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vanadyl sulfate, a form of vanadium, a mineral trace element. The tablet also includes inactive ingredients — lactose, microcrystalline cellulose, croscarmellose sodium, stearic acid, magnesium stearate, and silicon dioxide — which are fillers and binders that hold the tablet together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Vanadium's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Reduces post-exercise fatigue.
  • We looked for evidence on: Athletic performance, Exercise recovery, Muscle fatigue, Endurance.
  • The closest evidence on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

Vanadium is likely effective for vanadium deficiency. For athletic performance, cancer, diabetes, and high cholesterol, the evidence in our data is not sufficient to rate how well it works.

Small studies in people with type 2 diabetes suggest vanadyl sulfate may improve how the body uses insulin and lower blood sugar, but we don't have enough reliable data yet to call it proven for that use.

The evidence, ingredient by ingredient Vanadium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vanadium is generally well tolerated when you stay below 1.8 mg daily. At higher doses, it commonly causes stomach upset — bloating, diarrhea, nausea, and abdominal discomfort.

Rarely, long-term use at high doses may damage your kidneys. Allergic reactions to vanadium are uncommon but have been reported, including rashes, itchy eyes, and contact dermatitis in people exposed to vanadium metal or compounds.

The safety data advises against taking this supplement during pregnancy because there isn't enough information. Similarly, it's best to avoid vanadium supplements while breastfeeding since safety hasn't been established.

Side effects, ingredient by ingredient Vanadium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vanadium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you use blood thinners (anticoagulants) like warfarin or antiplatelet drugs like aspirin or clopidogrel — vanadium may increase bleeding risk. Also check if you take diabetes medications, since vanadium may lower blood sugar and raise the risk of hypoglycemia.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement may help if you have a documented vanadium deficiency, though deficiency is rare. If you take blood thinners or diabetes medications, check with your own doctor or pharmacist before starting — the interactions are real and could affect how well those drugs work or your risk of side effects.

Pregnancy and breastfeeding are times to skip it and talk with your healthcare provider instead.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vanadyl Sulfate, straight from the product label.

Brand Ultimate Nutrition Platinum Series
Barcode (UPC) 099071000873
Net contents 75 Tablet(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 293471
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vanadyl Sulfate by Ultimate Nutrition Platinum Series, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
75
UPC/BARCODE
099071000873
IngredientAmount% DV
Vanadyl Sulfate10 mg--

Other ingredients: Lactose, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one tablet daily with a meal, or as recommended by a health care professional.

Precautions

Do not use if seal under cap is broken or missing

Keep out of reach of children

Contains Milk

Storage

Store in a cool dry place

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Daily Pre During Post Night

Formulation

Reduces post-exercise fatigue

FDA Statement of Identity

Mineral Supplement

See for yourself

Vanadyl Sulfate by Ultimate Nutrition Platinum Series label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vanadyl Sulfate by Ultimate Nutrition Platinum Series

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container75 Amounts shown are per serving.

Vanadyl Sulfate

Interacts with
208 drugs
10 mg per serving

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadyl Sulfate monograph & interactions

Other (inactive) ingredients: Lactose, Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vanadyl Sulfate by Ultimate Nutrition Platinum Series Drug Interactions

Want to check YOUR meds against Vanadyl Sulfate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Vanadyl Sulfate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vanadyl Sulfate2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Vanadyl Sulfate, from the product label.

Ultimate Nutrition Platinum Series

See all Ultimate Nutrition Platinum Series products
Name
Ultimate Nutrition, Inc.
Street Address
P.O. Box 643
City
Farmington
State
CT
ZipCode
06034
Web Address
www.ultimatenutrition.com
Pharmacist Counseling Corner

Vanadyl Sulfate by Ultimate Nutrition Platinum Series: Common Questions

Does Vanadyl Sulfate by Ultimate Nutrition Platinum Series interact with any medications?
Yes. Based on its ingredients, Vanadyl Sulfate has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vanadyl Sulfate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my blood sugar or diabetes?
Very small clinical trials suggest vanadyl sulfate might improve insulin sensitivity and lower blood glucose, but we don't have enough reliable evidence yet to say it works for diabetes. If you have diabetes and want to try it, talk with your doctor first — especially if you take diabetes medications, since combining them could lower your blood sugar too much.
Can I take this while pregnant or breastfeeding?
The safety data advises against it during pregnancy because there isn't enough information. While breastfeeding, it's best to avoid vanadium supplements since safety hasn't been established. Talk with your doctor or pharmacist about what's right for you.
What are the side effects?
At doses above 1.8 mg daily, the most common side effects are stomach problems — nausea, diarrhea, gas, and belly discomfort. Rarely, long-term high-dose use may harm your kidneys. Some people can develop allergic reactions like rashes or itchy eyes, though that's uncommon.
Is vanadium a necessary mineral I'm probably low in?
Vanadium deficiency is very rare, and most people get enough from food. This supplement is mainly used if a deficiency has been identified, not as a routine nutrient booster.
How much is safe to take daily?
The tolerable upper intake level (the safe ceiling) is 1.8 mg daily. Amounts below that are generally well tolerated, but higher doses increase the risk of stomach upset and other side effects.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vanadyl Sulfate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vanadyl Sulfate label
Sources

Sources & How We Checked

Vanadyl Sulfate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
  3. Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
  4. Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
  5. Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
  6. Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
  9. Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
  10. Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
  11. Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
  12. Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
  13. Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
  14. Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
  15. Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed

See these in context on the Vanadium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring