Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Inositol 650 mg Ingredients & Drug Interactions

by Vitamin World

Inositol 650 mg label
See full label image
Other (e.g. Tea Bag) Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Inositol 650 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Inositol 650 mg is a dietary supplement by Vitamin World with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Inositol 650 mg by Vitamin World

Ask about any prescription or over-the-counter medication and we check it for interactions with Inositol 650 mg by Vitamin World — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Inositol 650 mg by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inositol at 650 mg per serving. Inositol is a naturally occurring compound related to the B vitamins that plays a role in cell signaling and metabolism.

The inactive ingredients are vegetable cellulose (the capsule material) and trace other ingredients making up less than 2 percent of the formula.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: essential for brain function.
  • We looked for evidence on: cognitive function, neurological health, mental clarity, brain support.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome. It's also possibly effective for preventing preterm labor.

However, the evidence doesn't support it for anxiety, diabetic nerve pain (neuropathy), or depression—it's rated possibly ineffective for those uses.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at typical doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea—usually mild and digestive in nature.

In pregnancy, inositol is rated possibly safe, but safety isn't fully established, so use it only under your doctor's supervision. There isn't enough reliable information on inositol during breastfeeding, so check with your doctor or pharmacist before using it if you're nursing.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start inositol, check with your doctor or pharmacist if you take any antidiabetes drugs (insulin, metformin, sulfonylureas, or other blood-sugar-lowering medications). Inositol itself lowers blood glucose, so combining it with these drugs could increase the risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Inositol may be worth considering if you have PCOS, metabolic syndrome, or want to explore options for preterm labor prevention—talk to your doctor about whether it fits your situation. If you take diabetes medications, you'll need to double-check with your own doctor or pharmacist before starting, since inositol can lower blood sugar.

The same goes if you're pregnant, nursing, or take any other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inositol 650 mg, straight from the product label.

Brand Vitamin World
Barcode (UPC) 074312707100
Net contents 100 Easy to Swallow Coated Caplet(s)
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 1175
Product type Non-nutrient/non-botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inositol 650 mg by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
UPC/BARCODE
074312707100
IngredientAmount% DV
Inositol650 mg--

Other ingredients: Vegetable Cellulose, Contains <2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

(C) 2011 Vitamin World, Inc..

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Vegetarian Dietary Supplement

Precautions

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Keep out of reach of children. Store in a cool, dry place. Do not use if seal under cap is broken or missing.

General

PROD. #710 B710 07E

General Statements

Essential for Brain Function*

Vitamin World products are subject to critically stringent quality assurance analysis. Our state-of-the-art laboratory, manufacturing and packaging facilities insure the highest quality nutritional supplements money can buy. Your health & safety are our first priority!

Get healthy.

Seals/Symbols

QUALITY ASSURED

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) caplet one to three times daily, preferably with meals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Inositol 650 mg by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Inositol 650 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Inositol 650 mg by Vitamin World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Inositol

Interacts with
86 drugs
650 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Contains <2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inositol 650 mg by Vitamin World Drug Interactions

Want to check YOUR meds against Inositol 650 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol 86

Individual Drug Interactions

The ingredients in Inositol 650 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Inositol 650 mg interact with drugs. Each result below shows which ingredient is responsible. Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Inositol 650 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Inositol 650 mg, from the product label.

Vitamin World

See all Vitamin World products
Phone Number
1-800-228-4533
Web Address
www.vitaminworld.com
Pharmacist Counseling Corner

Inositol 650 mg by Vitamin World: Common Questions

Does Inositol 650 mg by Vitamin World interact with any medications?
Yes. Based on its ingredients, Inositol 650 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inositol 650 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take inositol if I have diabetes?
If you have diabetes and take medications to lower your blood sugar, inositol isn't automatically off-limits—but you need to check with your doctor or pharmacist first. Inositol itself lowers blood glucose levels, so taking it alongside diabetes drugs could push your blood sugar too low. Your healthcare provider can tell you whether it's safe for you and whether your medication doses need adjusting.
What are the side effects of inositol?
The most common side effects are mild digestive ones: diarrhea, gas, and nausea. Overall, inositol is well tolerated at regular doses. If you're taking it with omega-3 fatty acids, watch for cold or allergy symptoms—a small number of children in clinical research reported those when using the combination.
Is inositol safe during pregnancy?
Inositol is rated possibly safe in pregnancy, but safety isn't fully established yet. If you're pregnant or thinking about becoming pregnant, talk with your doctor before starting inositol—they can weigh the evidence for your specific situation and decide whether it's right for you.
Can I take inositol while breastfeeding?
There isn't enough reliable information about inositol's safety while nursing. Check with your doctor or pharmacist before using it if you're breastfeeding—they can give you personalized guidance based on your health and your baby's needs.
Does inositol actually work for PCOS?
Inositol is possibly effective for polycystic ovary syndrome (PCOS), meaning some research supports it but more evidence is needed. It's also possibly effective for metabolic syndrome and preterm labor prevention. Talk with your doctor about whether it might help your situation and what else to expect.
Will inositol help my depression or anxiety?
The evidence doesn't support inositol for depression or anxiety—it's rated possibly ineffective for both. If you're managing either of those conditions, discuss other options with your doctor rather than relying on this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inositol 650 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inositol 650 mg label
Go deeper

The Full Monographs Behind Inositol 650 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Inositol 650 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team