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Dietary supplement

IP6 (Inositol Hexaphosphate) Ingredients & Drug Interactions

by Pure Encapsulations

IP6 (Inositol Hexaphosphate) label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking IP6 (Inositol Hexaphosphate) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

IP6 (Inositol Hexaphosphate) is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, cancer prevention interest, kidney stone prevention.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are IP6. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against IP6 (Inositol Hexaphosphate) by Pure Encapsulations

Ask about any prescription or over-the-counter medication and we check it for interactions with IP6 (Inositol Hexaphosphate) by Pure Encapsulations — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of IP6 (Inositol Hexaphosphate) by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: IP6 (inositol hexaphosphate), a compound found in plant sources. The capsule itself is made from inactive ingredients—cellulose, water, and hypoallergenic plant fiber—that help hold and deliver the active ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ip-6 product and its label doesn't state a use — see Ip-6's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for IP6's effectiveness isn't well established in the data we hold. Studies show insufficient reliable evidence to rate it for chemotherapy-induced leukopenia (low white blood cell counts after cancer treatment) and gout.

We don't have effectiveness ratings for other proposed uses either, so we can't tell you whether it's likely to work for any particular condition.

The evidence, ingredient by ingredient Ip-6

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

IP6 is generally well tolerated in the amounts found in food, but supplement-level safety isn't well studied. One caution: IP6 can reduce how your body absorbs minerals, so that's worth keeping an eye on if you take it long-term.

Because there isn't enough safety information, the data advises against using IP6 supplements during pregnancy or while breastfeeding—talk with your doctor or pharmacist about what's right for you if either applies.

Side effects, ingredient by ingredient Ip-6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ip-6.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any blood thinner or antiplatelet drug—warfarin, aspirin, clopidogrel, or similar medications—check with your doctor or pharmacist before using IP6. The interaction is moderate severity: IP6 may increase bleeding risk by inhibiting platelet function, though this hasn't been confirmed in people yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

IP6 is a single-ingredient supplement that's generally well tolerated but has weak evidence for any specific condition. If you take blood thinners or antiplatelet medications, you'll want to discuss this with your doctor or pharmacist before adding it.

For most people, the main question isn't whether it's safe in isolation, but whether it actually does what you're hoping for—and the research doesn't yet show that clearly.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about IP6 (Inositol Hexaphosphate), straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298003641
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 293986
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for IP6 (Inositol Hexaphosphate) by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
766298003641
IngredientAmount% DV
IP61000 mg--

Other ingredients: Cellulose, Water, hypoallergenic Plant Fiber

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store In a cool, dry place

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 2 capsules,1-2 daily, between meals.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Formulation

Certified Gluten free by the gluten free certification, www.gluten.org

Supports cellular health Gluten-free, Non-GMO & hypoallergenic

Gluten-free, Non-GMO & hypoallergenic

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any diseases.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

IP6 (Inositol Hexaphosphate) by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

IP6 (Inositol Hexaphosphate) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in IP6 (Inositol Hexaphosphate) by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

IP6

Interacts with
122 drugs
1000 mg per serving

IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supplement, ofte...

IP6 monograph & interactions

Other (inactive) ingredients: Cellulose, Water, Hypoallergenic Plant Fiber. These complete the product’s ingredient list but are not active constituents.

Interaction report

IP6 (Inositol Hexaphosphate) by Pure Encapsulations Drug Interactions

Want to check YOUR meds against IP6 (Inositol Hexaphosphate)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

IP6 122

Individual Drug Interactions

The ingredients in IP6 (Inositol Hexaphosphate) interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in IP6 (Inositol Hexaphosphate) interact with drugs. Each result below shows which ingredient is responsible. IP6

Each ingredient & the kinds of drugs it affects

For each ingredient in IP6 (Inositol Hexaphosphate) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

IP61 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of IP-6 with drugs that affect platelet aggregation may increase the risk of bleeding. In vitro IP-6 can inhibit platelet aggregation. This effect has not been demonstrated in humans.

Likelihood Unlikely Evidence D
IP6 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for IP6 (Inositol Hexaphosphate), from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

IP6 (Inositol Hexaphosphate) by Pure Encapsulations: Common Questions

Does IP6 (Inositol Hexaphosphate) by Pure Encapsulations interact with any medications?
Yes. Based on its ingredients, IP6 (Inositol Hexaphosphate) has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
IP6 (Inositol Hexaphosphate) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take IP6 if I'm pregnant or breastfeeding?
There isn't enough safety information to know either way. The data advises against supplemental IP6 during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about what's safest for you in your situation.
Does IP6 work for cancer treatment side effects like low white blood cell counts?
The evidence isn't strong enough yet to say. Studies show insufficient reliable evidence to rate IP6 for chemotherapy-induced leukopenia, so we don't know whether it actually helps.
Is there anything else in this supplement besides the active ingredient?
The capsule contains cellulose, water, and hypoallergenic plant fiber—these are inactive ingredients that help deliver the IP6. There are no other active ingredients.
What is IP6, and what does it do in the body?
IP6 (inositol hexaphosphate) is a compound found naturally in plant sources. It's proposed to have various health effects, but solid evidence for those effects in people is lacking. What we do know is that it can reduce mineral absorption, so long-term use is worth discussing with your pharmacist.
I'm on a blood thinner—is IP6 safe for me?
Not without checking first. IP6 may increase bleeding risk when combined with blood thinners or antiplatelet drugs. Check with your doctor or pharmacist before starting it—they can review your exact medication and advise you on whether it's okay.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

IP6 (Inositol Hexaphosphate) label
Go deeper

The Full Monographs Behind IP6 (Inositol Hexaphosphate)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ip-6

Interacts with 122 drugs

IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supplement, often paired with inositol. It is most studi...

Read the full Ip-6 monograph →
Sources

Sources & How We Checked

IP6 (Inositol Hexaphosphate)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ip-6 3 references
  1. Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc 1996;96:1027-39. PubMed
  2. Vucenik I, Podczasy JJ, Shamsuddin AM. Antiplatelet activity of inositol hexaphosphate. Anticancer Res 1999;19:3689-93.
  3. Ikenaga T, Kakumoto K, Kohda N, Yamamoto T. Effect of Inositol Hexaphosphate (IP6) on Serum Uric Acid in Hyperuricemic Subjects: a Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Plant Foods Hum Nutr. 2019 Sep;74(3):316-321. DOI

See these in context on the Ip-6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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