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Dietary supplement

Jing Jie Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Jing Jie is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for common cold and early-stage fever, itchy skin rashes and hives, sore throat.Based on those ingredients, 797 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Jing Jie (Schizonepeta tenuifolia) dried herb liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Jing Jie by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Jing Jie by Herbal Terra is a liquid extract containing one active ingredient: certified organic Jing Jie (Schizonepeta tenuifolia), a dried herb traditionally used in Asian medicine. The extract is prepared using a menstruum (a liquid solvent used to draw out the plant's active compounds).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Schizonepeta product and its label doesn't state a use — see Schizonepeta's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for schizonepeta's effectiveness in treating atopic dermatitis (eczema)—the condition listed here—is rated as insufficient reliable evidence to rate. That means there isn't enough solid research in humans to know whether it works for this purpose.

If you're considering it for another traditional use, we don't hold effectiveness data for that on file.

The evidence, ingredient by ingredient Schizonepeta

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Schizonepeta is generally used in small amounts in traditional herbal blends, but high-quality safety data in humans are limited. A combination product containing schizonepeta and other herbs has been linked to nausea, vomiting, stomach upset, dizziness, headache, and hair loss—though it's unclear whether schizonepeta alone caused these or whether the other ingredients were responsible.

At high doses, schizonepeta may be toxic to the liver due to one of its compounds (pulegone). Safety in pregnancy has not been established, so the data advises against use during pregnancy.

There isn't enough information to know if it's safe while breastfeeding—talk with your doctor or pharmacist for personalized guidance if you are or plan to become pregnant or are nursing.

Side effects, ingredient by ingredient Schizonepeta

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Schizonepeta.
  • The most serious interaction on file is rated Moderate.
  • For scale: 798 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Jing Jie, check with your doctor or pharmacist if you use any medications processed by liver enzymes—specifically any drugs broken down by CYP2D6, CYP1A2, CYP2E1, or CYP3A4. These include antidepressants, pain relievers, antipsychotics, muscle relaxants, acetaminophen, heart medications, cholesterol drugs, and antihistamines, among many others.

Use the medication checker on this page to review your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Jing Jie is a single-herb liquid extract that affects how your liver breaks down a large number of medications. If you take any prescription or regular over-the-counter drugs, check them against this product's interactions before starting.

Talk with your doctor or pharmacist about whether it's appropriate for you, especially if you're pregnant, breastfeeding, or considering high doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Jing Jie, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429524616628
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234914
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Jing Jie by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429524616628
IngredientAmount% DV
certified organic Jing Jie (Schizonepeta tenuifolia) dried herb liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Schizonepeta tenuifolia

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

See for yourself

Jing Jie by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Jing Jie by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

970 mg per serving

Schizonepeta is a mint-family herb long used in traditional Chinese medicine, usually as part of combination formulas for colds, fevers, and itchy ski...

Certified organic Jing Jie (Schizonepeta tenuifolia) dried herb liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Jing Jie by Herbal Terra Drug Interactions

Want to check YOUR meds against Jing Jie?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
797Drugs
797 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Jing Jie with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Jing Jie (Schizonepeta tenuifolia) dried herb liquid extract4 drug types · 797 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 1A2. Theoretically, schizonepeta might increase the effects and side effects of CYP1A2 substrates.
Some substrates of CYP1A2 include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2D6. Theoretically, schizonepeta might increase the effects and side effects of CYP2D6 substrates.
Some substrates of CYP2D6 include amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetine (Paxil), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), and others.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2E1. Theoretically, schizonepeta might increase the effects and side effects of CYP2E1 substrates.
Some substrates of CYP2E1 include acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, and anesthetics such as enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), and methoxyflurane (Penthrane).

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, induces cytochrome P450 (CYP) 3A4. Theoretically, schizonepeta might decrease the effects of CYP3A4 substrates.
Some substrates of CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and numerous others.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Jing Jie, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Jing Jie by Herbal Terra: Common Questions

Does Jing Jie by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Jing Jie has a known interaction with 797 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Jing Jie contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Jing Jie used for traditionally?
Jing Jie (Schizonepeta tenuifolia) is an herb traditionally used in Asian medicine, often included in formulas for various purposes. We don't hold detailed traditional use information in our data, but it's been a staple of herbal practice for centuries.
Does this product actually work for eczema?
The evidence for schizonepeta's effectiveness in atopic dermatitis (eczema) is rated as insufficient reliable evidence to rate—meaning there isn't enough solid research in humans to know whether it works for this condition.
What are the side effects?
Limited human safety data exist for schizonepeta alone. A combination herbal product containing it has been associated with nausea, vomiting, stomach upset, dizziness, headache, and hair loss, though it's unclear whether schizonepeta or the other ingredients caused these. High doses may be toxic to the liver.
Is it safe to take if I'm pregnant or breastfeeding?
Safety in pregnancy has not been established, so it's best avoided during pregnancy. There isn't enough information to know if it's safe while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you are or plan to become pregnant or are nursing.
Why does this product interact with so many medications?
Schizonepeta contains a compound (schizonepetin) that affects multiple liver enzymes responsible for breaking down hundreds of different medications. When those enzymes are inhibited or sped up, drug levels in your body can change—making some more potent and others less effective.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Jing Jie label
Sources

Sources & How We Checked

Jing Jie's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Schizonepeta 4 references
  1. Fung D, Lau CB. Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications. J Clin Pharmacol 2002;42:30-6. PubMed
  2. Zhou S, Koh HL, Gao Y, et al. Herbal bioactivation: the good, the bad and the ugly. Life Sci 2004;74:935-68. PubMed
  3. Fung AY, Look PC, Chong LY, et al. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. Int J Dermatol 1999;38:387-92 . PubMed
  4. Bao B, Geng T, Cao Y, et al. Effects of schizonepetin on activity of mRNA expression of cytochrome P450 enzymes in rats. Int J Mol Sci. 2012;13(12):17006-18.

See these in context on the Schizonepeta monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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