Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

JointGel Delicious Mixed Berry Flavor Ingredients & Drug Interactions

by Purity Products

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

JointGel Delicious Mixed Berry Flavor is a dietary supplement by Purity Products with 4 active ingredients. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of JointGel Delicious Mixed Berry Flavor by Purity Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

JointGel contains three active ingredients. Stevia leaf extract is a sweetener derived from the stevia plant.

OptiMSM is methylsulfonylmethane, a naturally occurring compound. Fortigel B Gelatin Hydrolysate is a collagen-derived protein.

The powder also contains inactive ingredients including citric acid, pineapple fruit powder, natural flavor, silicon dioxide, and beet root powder.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: joint comfort and cartilage health support.
  • We looked for evidence on: Joint pain, Osteoarthritis, Rheumatoid arthritis (RA), Joint flexibility, Cartilage integrity, Collagen synthesis.
  • The closest evidence on file: Gelatin is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis (Natural Medicines).
  • Also on file: Gelatin is rated "Insufficient Reliable Evidence To Rate" for Joint pain, Rheumatoid arthritis (RA).

The evidence for stevia's effects on diabetes, blood pressure, and weight is not established in the data we hold — the ratings show insufficient reliable evidence. Gelatin hydrolysate shows possibly ineffective evidence for diarrhea, and insufficient evidence for aging skin, brittle nails, and other conditions.

We do not have effectiveness data on file for OptiMSM.

The evidence, ingredient by ingredient Stevia Gelatin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia at food levels is generally recognized as safe, though whole-leaf stevia and high-dose supplements lack thorough safety data — use caution with this product. The most common mild side effects are bloating, dizziness, headache, muscle pain, nausea, and numbness; most resolve after the first week.

Allergic reactions are rare but possible. Gelatin is widely consumed in food and generally well tolerated, though it can cause belching, bloating, indigestion, and unpleasant taste.

Gelatin can cause allergic reactions in susceptible people, including serious ones like anaphylaxis, especially in those with a known gelatin sensitivity. For pregnancy, gelatin is rated likely safe or possibly safe.

Stevia's pregnancy and lactation data are not on file — talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Stevia Gelatin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your own doctor or pharmacist before using JointGel if you take lithium, blood pressure medication, or diabetes medication. Stevia has documented Moderate and Minor interactions with all three.

We could not check OptiMSM for drug interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

JointGel may be worth considering if you're interested in gelatin and stevia, but it's not right for everyone. If you take lithium, blood pressure medication, or diabetes medication, you'll need to clear it with your own doctor or pharmacist first — the stevia raises safety questions with those drugs.

Pregnant or breastfeeding? Check with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about JointGel Delicious Mixed Berry Flavor, straight from the product label.

Brand Purity Products
Net contents 8.4 Ounce(s); 238 Gram(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 243783
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for JointGel Delicious Mixed Berry Flavor by Purity Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8.5 Gram(s)
Maximum serving Sizes:
8.5 Gram(s)
Servings per container
28
IngredientAmount% DV
Calories30 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Protein5 Gram(s)--
Stevia leaf extract120 mg--
OptiMSM Methylsulfonylmethane1.5 Gram(s)--
Fortigel B Gelatin Hydrolysate5 Gram(s)--

Other ingredients: Citric Acid, Pineapple fruit powder, Natural flavor, Silicon Dioxide, Beet root powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Intelligent nutritional solutions

Premium grade supplements Since 1993

Formula

Fortigel + OptiMSM

Formulation

Cartilage fortification advanced support Promotes joint comfort Promotes healthy joint cartilage

GF Gluten free Made without GMO Allergen free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Mix 1 scoop daily in about 12 fl. oz. of pure, cold water. You may take 1 serving two times a day if desired. Taste tip: Add a few ice cubes before mixing.

Brand IP Statement(s)

Fortigel is registered trademark of GELITA USA, OptiMSM is registered trademark of Bergstrom Nutrition.

Seals/Symbols

Lab Tested in the USA

Made in a GMP Certified Facility

See for yourself

JointGel Delicious Mixed Berry Flavor by Purity Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in JointGel Delicious Mixed Berry Flavor by Purity Products

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size8.5 Gram(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

5 Gram(s) per serving

Stevia leaf extract

Interacts with
259 drugs
120 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia leaf extract monograph & interactions

OptiMSM Methylsulfonylmethane

1.5 Gram(s) per serving

Fortigel B Gelatin Hydrolysate

No known
interactions
5 Gram(s) per serving

Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most heal...

Fortigel B Gelatin Hydrolysate monograph & interactions

Other (inactive) ingredients: Citric Acid, Pineapple fruit powder, Natural flavor, Silicon Dioxide, Beet root powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

JointGel Delicious Mixed Berry Flavor by Purity Products Drug Interactions

Want to check YOUR meds against JointGel Delicious Mixed Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in JointGel Delicious Mixed Berry Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia leaf extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for JointGel Delicious Mixed Berry Flavor, from the product label.

Purity Products

See all Purity Products products
Name
Purity Products
Pharmacist Counseling Corner

JointGel Delicious Mixed Berry Flavor by Purity Products: Common Questions

Does JointGel Delicious Mixed Berry Flavor by Purity Products interact with any medications?
Yes. Based on its ingredients, JointGel Delicious Mixed Berry Flavor has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
JointGel Delicious Mixed Berry Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this have stevia in it? I've heard stevia can lower blood pressure.
Yes — stevia leaf extract is one of the three active ingredients. It may theoretically lower blood pressure, but the evidence in our data is insufficient to say whether it actually does. If you take blood pressure medication, talk to your doctor or pharmacist before starting JointGel.
What's the gelatin in here for?
Fortigel B Gelatin Hydrolysate is a type of collagen protein. The evidence for what it does is mixed — it's rated possibly ineffective for diarrhea and insufficient for skin, nails, and other uses listed in our data.
Can I take this if I'm on lithium?
Not without checking with your doctor or pharmacist first. Stevia in this product may slow how your body clears lithium, raising levels to unsafe amounts — that's a Moderate-severity interaction. Your provider needs to weigh the risks and possibly adjust your dose.
What side effects might I get from stevia?
The most common ones are bloating, dizziness, headache, muscle pain, nausea, and numbness. Most of these mild effects resolve after the first week. Allergic reactions are rare but possible.
Will the gelatin give me side effects?
Gelatin is generally well tolerated. Mild side effects may include belching, bloating, indigestion, or an unpleasant taste. If you're allergic to gelatin, avoid this product — allergic reactions can be serious.
Is it safe to take while pregnant?
Gelatin is rated likely or possibly safe in pregnancy. We don't have pregnancy safety data on file for stevia or OptiMSM — talk with your doctor or pharmacist about whether JointGel is right for you during pregnancy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if JointGel Delicious Mixed Berry Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

JointGel Delicious Mixed Berry Flavor label
Sources

Sources & How We Checked

JointGel Delicious Mixed Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Gelatin 11 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Schwick HG, Heide K. Immunochemistry and immunology of collagen and gelatin. Bibl Haematol 1969;33:111-25. PubMed
  3. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease.Semin Arthritis Rheum 2000;30:87-99. PubMed
  4. Kelso JM. The gelatin story. J Allergy Clin Immunol 1999;103:200-2.
  5. Nakayama T, Aizawa C, Kuno-Sakai H. A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids. J Allerg PubMed
  6. Sakaguchi M, Inouye S. Anaphylaxis to gelatin-containing rectal suppositories. J Allergy Clin Immunol 2001;108:1033-4. PubMed
  7. PDR Electronic Library. Montvale, NJ: Medical Economics Company, Inc., 2001.
  8. de la Fuente Tornero E, Vega Castro A, de Sierra Hernández PÁ, et al. Kounis syndrome during anesthesia: Presentation of indolent systemic mastocytosis: A case report. A Case Rep. 2017;8(9):226-228. PubMed
  9. Ventura Spagnolo E, Calapai G, Minciullo PL, Mannucci C, Asmundo A, Gangemi S. Lethal anaphylactic reaction to intravenous gelatin in the course of surgery. Am J Ther. 2016;23(6):e1344-e1346. PubMed
  10. Li Y, He H, Yang L, Li X, Li D, Luo S. Therapeutic effect of Colla corii asini on improving anemia and hemoglobin compositions in pregnant women with thalassemia. Int J Hematol. 2016;104(5):559-565. PubMed
  11. Coury JR, Skaggs KF, Marciano GF, et al. Intraoperative Anaphylaxis to the Bovine Flowable Gelatin Matrix: A Report of 2 Cases. JBJS Case Connect 2022;12(1). PubMed

See these in context on the Gelatin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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