Kid's Potty Helper Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Kid's Potty Helper against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Kid's Potty Helper is a dietary supplement by Village Vitality with 4 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and stomach upset, mouth ulcers and digestive complaints.Based on those ingredients, 2,121 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are fresh Marshmallow, Licorice, Peppermint Spirits. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Kid's Potty Helper by Village Vitality
Ask about any prescription or over-the-counter medication and we check it for interactions with Kid's Potty Helper by Village Vitality — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Kid's Potty Helper by Village Vitality
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Kid's Potty Helper contains four active ingredients. The product includes a proprietary blend alongside licorice, yellow dock, peppermint (as peppermint spirits), and fresh marshmallow.
The inactive ingredients are vegetable glycerin, deionized water, and raspberry natural flavor — the first two are the liquid base, and the third is for taste.
Does it work?
Strong evidence
Licorice has possibly effective evidence for canker sores and eczema (atopic dermatitis), though it lacks reliable evidence for Addison disease and asthma. Peppermint is likely effective for irritable bowel syndrome and possibly effective for indigestion, nausea from chemotherapy, and reducing colon spasms during medical procedures.
Marshmallow lacks established evidence in our data for the conditions listed — vaginal yeast infections, diarrhea, skin conditions, and respiratory infections are all rated insufficient evidence. The product's own purpose ("potty helper") isn't addressed in the effectiveness data we hold.
How safe is it?
Well-documented data
Licorice is generally well tolerated in small food amounts, but the active compound glycyrrhizin can cause serious problems with high doses or long-term use — the most common side effects are headache, nausea, and vomiting. Yellow dock acts as a mild laxative and should be used short-term; raw leaves or rhizomes can cause low blood calcium, kidney stones, and vomiting.
Peppermint oil is generally well tolerated but concentrated oil needs careful use — common effects include abdominal pain, heartburn, nausea, and anal burning. Marshmallow is generally well tolerated for short-term use, though human safety data are limited.
During pregnancy, licorice and yellow dock are best avoided due to links to harmful effects; safety data for marshmallow and peppermint oil in pregnancy are insufficient, so check with your provider. While breastfeeding, yellow dock and licorice are best avoided (laxative compounds and insufficient data, respectively), and peppermint oil should be limited to food amounts.
Meds to double-check
Major interaction found
Check these medication types before giving this product: diuretics and digoxin (Major severity, from yellow dock); blood thinners like warfarin (Moderate, from both licorice and yellow dock); heart-rate or blood-pressure medications metabolized by the liver (Moderate, from licorice and peppermint); lithium (Moderate, from marshmallow); and cyclosporine (Moderate, from peppermint). Space any oral medications 30–60 minutes apart from this liquid to avoid absorption problems.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This product combines four herbal ingredients with established and potential interactions with heart medications, blood thinners, diuretics, and mood stabilizers. If your child (or you, if buying for yourself) takes any prescription medications — especially heart, kidney, or psychiatric medications — check your specific drugs with the tool on this page before starting.
Short-term use in food-level amounts is generally well tolerated, but the product is not appropriate for long-term daily use.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Kid's Potty Helper, straight from the product label.
| Brand | Village Vitality |
|---|---|
| Barcode (UPC) | 788332068416 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2020 |
| DSLD ID | 215887 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Children (All), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Kid's Potty Helper by Village Vitality, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 411 mg | -- |
| Licorice | 0 NP | -- |
| Yellow Dock | 0 NP | -- |
| Peppermint Spirits | 0 NP | -- |
| fresh Marshmallow | 0 NP | -- |
Other ingredients: Vegetable Glycerin, deionized Water, Raspberry natural flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: 10-30 lbs. use 10-20 drops, 31-60 lbs. use 20-40 drops, 61-100 lbs. use 40-60 drops, over 100 lbs. use 60-90 drops, 2-3 times per day or as needed in juice or water. Shake well before using.
Precautions
Warning: Do not take during pregnancy or while nursing.
Keep out of the reach of children.
Formulation
Alcohol free
FDA Statement of Identity
Herbal Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Kid's Potty Helper by Village Vitality label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Kid's Potty Helper by Village Vitality
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.33 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
Other (inactive) ingredients: Vegetable Glycerin, Deionized Water, Raspberry natural flavor. These complete the product’s ingredient list but are not active constituents.
Kid's Potty Helper by Village Vitality Drug Interactions
HelloPharmacist Interaction Report
Kid's Potty Helper by Village Vitality contains four active ingredients, three of which have documented interactions with medications.
The most serious concern is yellow dock, which poses Major-severity risks with diuretic drugs (water pills) and digoxin, a heart medication — both can lead to dangerously low potassium levels and heart toxicity if combined.
Read the full breakdown — every affected drug type, severity by severity
Licorice carries Moderate-severity interactions with blood thinners like warfarin, heart medications including digoxin, and several drug-metabolizing pathways. It may reduce warfarin's effectiveness and increase the risk of heart toxicity.
Peppermint oil also has Moderate interactions with multiple metabolic pathways and cyclosporine, an immunosuppressant. Marshmallow poses Minor-severity concerns with lithium (a mood stabilizer) and can theoretically impair absorption of oral medications if taken at the same time.
Altogether, these interactions span 2,102 individual medications. We hold no interaction data for the proprietary blend itself, but its component ingredients are listed above.
Please use the medication checker below to verify your specific prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Kid's Potty Helper?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Kid's Potty Helper interact with 2,121 drugs. Click any drug to see the details.
4 of the 4 ingredients in Kid's Potty Helper interact with drugs. Each result below shows which ingredient is responsible. fresh Marshmallow Licorice Peppermint Spirits Yellow Dock
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Kid's Potty Helper — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Acetaminophen, Caffeine, Pyrilamine interactionLicoriceDiuretic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Acetaminophen, Caffeine, Pyrilamine interactionPeppermint SpiritsCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Spirits + Acetaminophen, Caffeine, Pyrilamine interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Kid's Potty Helper — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Acetaminophen, Pamabrom, Pyrilamine interactionLicoriceDiuretic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Acetaminophen, Pamabrom, Pyrilamine interactionPeppermint SpiritsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Spirits + Acetaminophen, Pamabrom, Pyrilamine interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Acetazolamide interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Acetazolamide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Acetazolamide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Amiloride, Hydrochlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Amiloride, Hydrochlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Ammonium Chloride interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Ammonium Chloride interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Ammonium Chloride interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Atenolol, Chlortalidone interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Atenolol, Chlortalidone interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Atenolol, Chlorthalidone interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Atenolol, Chlorthalidone interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Atenolol, Chlorthalidone interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Kid's Potty Helper — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Azilsartan, Chlorthalidone interactionLicoriceAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Azilsartan, Chlorthalidone interactionPeppermint SpiritsCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP2C9 substrates.
Read the full Peppermint Spirits + Azilsartan, Chlorthalidone interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Azilsartan, Chlorthalidone interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Benazepril, Hydrochlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Benazepril, Hydrochlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bendroflumethiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Bendroflumethiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bendroflumethiazide, Nadolol interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Bendroflumethiazide, Nadolol interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bendroflumethiazide, Potassium interactionLicoriceDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Bendroflumethiazide, Potassium interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bendroflumethiazide, Rauwolfia Serpentina interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Bendroflumethiazide, Rauwolfia Serpentina interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Benzthiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Benzthiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Benzthiazide interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bisoprolol, Hydrochlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Bisoprolol, Hydrochlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bisoprolol, Hydrochlorothiazide interactionBumetanideBurinex
How Bumetanide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bumetanide interactionLicoriceDiuretic Drugs, Loop Diuretics +1 Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Bumetanide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bumetanide interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Bumetanide, Potassium interactionLicoriceDiuretic Drugs, Loop Diuretics Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Bumetanide, Potassium interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Bumetanide, Potassium interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Kid's Potty Helper — through 4 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Caffeine, Potassium Salicylate, Salicylamide interactionLicoriceDiuretic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Caffeine, Potassium Salicylate, Salicylamide interactionPeppermint SpiritsCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Spirits + Caffeine, Potassium Salicylate, Salicylamide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Caffeine, Potassium Salicylate, Salicylamide interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Candesartan Cilexetil, Hydrochlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Candesartan Cilexetil, Hydrochlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Captopril, Hydrochlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Captopril, Hydrochlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Captopril, Hydrochlorothiazide interactionChlorothiazideDiuril
How Chlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Chlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Chlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Chlorothiazide, Methyldopa interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Chlorothiazide, Methyldopa interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Chlorothiazide, Reserpine interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Chlorothiazide, Reserpine interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Chlorthalidone interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Chlorthalidone interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Chlorthalidone, Clonidine interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Chlorthalidone, Clonidine interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Chlorthalidone, Clonidine interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Cryptenamine, Methyclothiazide interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Cryptenamine, Methyclothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Cyclothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Cyclothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Cyclothiazide interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Deserpidine, Hydrochlorothiazide interactionLicoriceAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Deserpidine, Hydrochlorothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDiuretic Drugs Major
Interaction Summary
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
Read the full Yellow Dock + Deserpidine, Methyclothiazide interactionLicoriceDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Read the full Licorice + Deserpidine, Methyclothiazide interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Deserpidine, Methyclothiazide interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Kid's Potty Helper — through 3 ingredients. Tap an ingredient for the detail:
Yellow DockDigoxin (lanoxin) Major
Interaction Summary
Theoretically, yellow dock might increase the risk of digoxin toxicity when used long-term or in large amount.
Read the full Yellow Dock + Digoxin interactionLicoriceDigoxin (lanoxin), P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Read the full Licorice + Digoxin interactionFresh MarshmallowOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Fresh Marshmallow + Digoxin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Kid's Potty Helper with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
fresh Marshmallow
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
Licorice
Antihypertensive Drugs
Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.
Cisplatin (Platinol-Aq)
Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.
Corticosteroids
Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.
Digoxin (Lanoxin)
Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Diuretic Drugs
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.
Estrogens
Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.
Loop Diuretics
Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.
Midazolam (Versed)
Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.
P-Glycoprotein Substrates
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.
Paclitaxel (Abraxane, Onxol)
Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.
Warfarin (Coumadin)
Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.
Methotrexate (Trexall, Others)
Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.
Peppermint Spirits
Cyclosporine (Neoral, Sandimmune)
Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.
Yellow Dock
Digoxin (Lanoxin)
Theoretically, yellow dock might increase the risk of digoxin toxicity when used long-term or in large amount.
When yellow dock is used chronically or in large amounts, hypokalemia may occur. This might increase the toxic effects of digoxin.
Diuretic Drugs
Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
When yellow dock is used chronically or in large amounts, hypokalemia may occur, and overuse of yellow dock might compound diuretic-induced potassium loss.
Warfarin (Coumadin)
Theoretically, the laxative effects of yellow dock might increase the effects of warfarin, including the risk of bleeding.
The anthraquinones in yellow dock have a mild stimulant laxative effect. Consuming excessive amounts can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding.
Brand information
Manufacturer and brand details for Kid's Potty Helper, from the product label.
Village Vitality
See all Village Vitality products- Name
- Village Vitality LLC
- Street Address
- 79 Tinker St. Floor 2
- City
- Woodstock
- State
- NY
- ZipCode
- 12498
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Kid's Potty Helper’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Licorice
Interacts with 1,040 drugsLicorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...
Read the full Licorice monograph → Herb & supplement monographYellow Dock
Interacts with 78 drugsYellow dock is a traditional herb used mostly as a mild laxative and a digestive and skin tonic. Good-quality human studies are lacking, so its benefits are largely unproven, and its natural...
Read the full Yellow Dock monograph → Herb & supplement monographPeppermint
Interacts with 796 drugsPeppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...
Read the full Peppermint monograph → Herb & supplement monographMarshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph →Sources & How We Checked
Kid's Potty Helper's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 146 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Licorice 92 references
- Farese RV Jr, Biglieri EG, Shackleton CH, et al. Licorice-induced hypermineralocorticoidism. N Engl J Med 1991;325:1223-7. PubMed
- Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? J Hum Hypertens 1995;9:345-8.
- Armanini D, Lewicka S, Pratesi C, et al. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. J Endocrinol Invest 1996;19:624-9. PubMed
- Zhang YD, Lorenzo B, Reidenberg MM. Inhibition of 11 beta hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. J Steroid Biochem Mol Biol 1994;49:81-5.
- Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Birth outcome in relation to licorice consumption during pregnancy. Am J Epidemiol 2001;153:1085-8. PubMed
- Sigurjonsdottir HA, Franzson L, Manhem K, et al. Liquorice-induced rise in blood pressure: a linear dose-response relationship. J Hum Hypertens 2001;15:549-52. PubMed
- Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
- Kent UM, Aviram M, Rosenblat M, Hollenberg PF. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. Drug Metab Dispos 2002;30:709-15.. PubMed
- Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Clin Neurol Neurosurg 2003;105:286-7.. PubMed
- Strandberg TE, Andersson S, Jarvenpaa AL, et al. Preterm birth and licorice consumption during pregnancy. Am J Epidemiol 2002;156:803-5.. PubMed
- Hussain RM. The sweet cake that reaches parts other cakes can't! Postgrad Med J 2003;79:115-6.. PubMed
- Morris DJ, Davis E, Latif SA. Licorice, tobacco chewing, and hypertension. N Engl J Med 1990;322:849-50. PubMed
- Quinkler M, Stewart PM. Hypertension and the cortisol-cortisone shuttle. J Clin Endocrinol Metab 2003;88:2384-92. PubMed
- Westman EC, Guthrie GP. Licorice, tobacco chewing, and hypertension. N Engl J Med 1990;322:850. PubMed
- Mu Y, Zhang J, Zhang S, et al. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. J Pharmacol Exp Ther 2006;316:1369-77. PubMed
- Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Intern Med 2007;46:575-8. PubMed
- Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). Am J Psychiatry 1994;151:617-8. PubMed
- de Klerk GJ, Nieuwenhuis G, Beutler JJ. Hypokalaemia and hypertension associated with use of liquorice flavoured chewing gum. BMJ 1997;314:731-2.
- Dellow EL, Unwin RJ, Honour JW. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. Nephol Dial Transplant 1999;14:218-20. PubMed
- Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Mayo Clin Proc 2003;78:767-8. PubMed
- Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. J Intern Med 1999;245:307-10.
- Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. The old lady who liked liquorice: hypertension due to chronic intoxication in a memory-impaired patient. Neth J Med 2005;63:149-50.
- Lin SH, Yang SS, Chau T, Halperin ML. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Am J Med Sci 2003;325:153-6. PubMed
- van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. Neth J Med 2005;63:146-8.
- van Uum SH. Liquorice and hypertension. Neth J Med 2005;63:119-20.
- Russo S, Mastropasqua M, Mosetti MA, et al. Low doses of liquorice can induce hypertension encephalopathy. Am J Nephrol 2000;20:145-8. PubMed
- Stormer FC, Reistad R, Alexander J. Glycyrrhizic acid in liquorice - evaluation of health hazard. Food Chem Toxicol 1993;31:303-12. PubMed
- Sontia B, Mooney J, Gaudet L, Touyz RM. Pseudohyperaldosteronism, liquorice, and hypertension. J Clin Hypertens (Greenwich) 2008;10:153-7. PubMed
- Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. Phytother Res 2008;22:563-5. PubMed
- Lapi F, Gallo E, Bernasconi S, et al. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. Br J Clin Pharmacol 2008;66:572-4. PubMed
- Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. Endocrinol Jpn 1990;37:331-41. PubMed
- Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Lancet 1990;335(8697):1060-3. PubMed
- Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Klin Wochenschr 1983;61:303-5. PubMed
- Hukkanen J, Ukkola O, Savolainen MJ. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. Blood Press 2009;18:192-5. PubMed
- Bisogni V, Rossi GP, Calò LA. Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. Blood Press. 2014 Jun;23(3):189-92. PubMed
- Dehours E, Vallé B, Rougé-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. J Telemed Telecare. 2013 Jun;19(4):227-8. PubMed
- Kormann R, Languille E, Amiot HM, Hertig A. Dying for a cup of tea. BMJ Case Rep. 2012 Oct 19;2012. PubMed
- Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Ann Noninvasive Electrocardiol. 2013 Nov;18(6):593-6. PubMed
- Räikkönen K, Seckl JR, Heinonen K, Pyhälä R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Järvenpää AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis fu
- Robles BJ, Sandoval AR, Dardon JD, Blas CA. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). BMJ Case Rep. 2013 Sep 19;2013. PubMed
- Chamberlain, J. J. and Abolnik, I. Z. Pulmonary edema following a licorice binge. West J Med 1997;167(3):184-185.
- Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. Ital.J Neurol.Sci 1997;18(4):217-220. PubMed
- Fugh-Berman, A. Herb-drug interactions. Lancet 2000;355(9198):134-138. PubMed
- Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. Cardiovasc.Drugs Ther 1998;12(6):59 PubMed
- van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. J Gastroenterol Hepatol 199 PubMed
- Lozano, P., Flores, D., Martinez, S., Artigues, I., Rimbau, E. M., and Gomez, F. Upper limb ischemia induced by chronic licorice ingestion. J Cardiovasc.Surg (Torino) 2000;41(4):631-632.
- Brouwers, A. J. and van der, Meulen J. ['Licorice hypertension' also caused by licorice tea]. Ned.Tijdschr Geneeskd. 4-14-2001;145(15):744-747.
- van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. PubMed
- Sigurjonsdottir, H. A., Manhem, K., Axelson, M., and Wallerstedt, S. Subjects with essential hypertension are more sensitive to the inhibition of 11 beta-HSD by liquorice. J Hum Hypertens 2003;17(2):125-131.
- Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Report of 2 cases and review of the literature. Eur Neurol 1992;32(1):44-51. PubMed
- Chen, M. F., Shimada, F., Kato, H., Yano, S., and Kanaoka, M. Effect of oral administration of glycyrrhizin on the pharmacokinetics of prednisolone. Endocrinol Jpn 1991;38(2):167-174. PubMed
- Lee, C. K., Park, K. K., Lim, S. S., Park, J. H., and Chung, W. Y. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. Biol Pharm Bull 2007;30(11):2191-2195. PubMed
- Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. Minerva Med 2008;99(1):91-94.
- Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. Z Kardiol 1991;80(6):389-391.
- Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. J Peripher.Nerv.Syst. 2009;14(1):64-65. PubMed
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