Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Krill Omega 10X with CoQ10 Ingredients & Drug Interactions

by Purity Products

Krill Omega 10X with CoQ10 label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Krill Omega 10X with CoQ10 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Krill Omega 10X with CoQ10 is a dietary supplement by Purity Products with 6 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 1,008 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D, natural Astaxanthin, Omega-3 Fatty Acids. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Krill Omega 10X with CoQ10 by Purity Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Krill Omega 10X with CoQ10 by Purity Products — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Krill Omega 10X with CoQ10 by Purity Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • “Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (1,150 mg) without saying how much of each component you get.
  • “Enriched Omega-3 Blend” is a proprietary blend — the label gives one combined amount (2,300 mg) without saying how much of each component you get.

Krill Omega 10X with CoQ10 contains 7 active ingredients. The core is an enriched krill omega-3 blend — that's a concentrated source of two omega-3 fatty acids, eicosapentaenoic acid and docosahexaenoic acid, plus phospholipids that help your body absorb them.

Added to that are vitamin D (cholecalciferol), coenzyme Q10 (a compound your cells use for energy), and natural astaxanthin, a pigment with antioxidant properties. The softgel capsule also contains inactive ingredients — a capsule shell, beeswax, and a proprietary blend for freshness — but these are not actives.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Promotes brain health, joint function and cardiovascular health.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive function, Cognitive impairment, Dementia, Cardiovascular disease (CVD) — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Likely Effective" for Coenzyme Q10 deficiency (Natural Medicines).
  • Also on file: Vitamin D is rated "Possibly Effective" for Heart failure.
  • Also on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF).

The evidence for this product's ingredients is mixed. Vitamin D is established as effective for rickets, osteomalacia (soft bones), renal bone disease, and certain calcium-regulation disorders.

Coenzyme Q10 is likely effective for CoQ10 deficiency itself, and possibly effective for fibromyalgia, migraines, heart failure, and diabetic nerve damage. Astaxanthin, however, has insufficient evidence to rate — we don't have reliable data on whether it works for age-related cognitive decline, macular degeneration, skin aging, or other proposed uses.

The omega-3 fatty acids themselves and total phospholipids in this product have no effectiveness ratings on file.

The evidence, ingredient by ingredient Vitamin D Coenzyme Q10 Docosahexaenoic Acid (dha) Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D is generally well tolerated at recommended doses, though very high doses over time can cause toxicity — symptoms include high blood calcium (hypercalcemia), weak bones in adults, slow growth in children, and in rare cases eye inflammation and light sensitivity. CoQ10 is also generally well tolerated; the most common side effects are mild gastrointestinal upset (appetite loss, diarrhea, nausea, heartburn) in less than 1% of users, and rarely headache, dizziness, insomnia, or skin itching.

Astaxanthin seems well tolerated in studies, though long-term safety data are limited; reported side effects include abdominal pain, diarrhea, and red-colored stools. For pregnancy: there isn't enough safety data for astaxanthin, so it's best avoided during pregnancy and breastfeeding.

Vitamin D is often used at recommended doses during pregnancy, but only under a doctor's guidance. CoQ10 hasn't been studied enough in pregnancy or breastfeeding — talk with your doctor before using if you're pregnant or nursing.

Side effects, ingredient by ingredient Vitamin D Coenzyme Q10 Docosahexaenoic Acid (dha) Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Vitamin D, Coenzyme Q10, Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
  • For scale: 851 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners like warfarin are the top concern — both vitamin D and CoQ10 can reduce their effect. Heart rhythm medications (verapamil, diltiazem, digoxin) and the cholesterol drug atorvastatin are also affected by vitamin D.

Water pills (thiazide diuretics), blood pressure medications, and any drugs your liver breaks down via CYP3A4 or CYP2B6 pathways warrant a check too. Use the search tool on this page with your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is worth considering if you're looking for omega-3s plus vitamin D and CoQ10 support, and you don't take blood thinners or certain heart or cholesterol medications. If you take warfarin, verapamil, diltiazem, digoxin, atorvastatin, thiazide diuretics, or any medication metabolized by your liver, check with your pharmacist first — the interactions here are real and could affect how your drugs work.

Always run your exact medication list through the interaction checker below before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Krill Omega 10X with CoQ10, straight from the product label.

Brand Purity Products
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 243789
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Krill Omega 10X with CoQ10 by Purity Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
IngredientAmount% DV
Calories25 Calorie(s)--
Calories from Fat20 Calorie(s)--
Omega-3 Fatty Acids1150 mg--
Total Fat2.5 Gram(s)4%
Eicosapentaenoic Acid450 mg--
Docosahexaenoic Acid600 mg--
Cholesterol15 mg5%
Protein1 Gram(s)--
Vitamin D1000 IU250%
Other Omega-3 Fatty Acids100 mg--
Coenzyme Q10100 mg--
Total Phospholipids120 mg--
natural Astaxanthin300 mcg--
Enriched Omega-3 Blend2300 mg--

Other ingredients: Enriched Krill Omega-3 Blend, Capsule Shell, Beeswax, CoQ10, Proprietary LemonLock Freshness System, Astaxanthin extract, Cholecalciferol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Intelligent nutritional solutions

Premium grade supplements Since 1993

Formula

300 mg krill 2,000 mg Omega-3 marine oil 100 mg coenzyme Q10

Formulation

Promotes brain health & joint function Supports cardiovascular health & function

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 2 softgels daily. For daily use.

Precautions

Warning: Do not take if allergic to shellfish.

Contains crustacean shellfish, fish and soy.

Do not use if safety seal is broken.

Brand IP Statement(s)

NKO is a registered trademark of Neptune Technologies and Bioressources Inc., Quebec, Canada. Neptune Krill Oil NKO Original Calamarine is a registered trademark of Pharma Marine. Various patents apply. BioMarine is a registered trademark of Marine Ingredients LLC.

Seals/Symbols

Friend of the Sea

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Krill Omega 10X with CoQ10 by Purity Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Krill Omega 10X with CoQ10 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Krill Omega 10X with CoQ10 by Purity Products

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Vitamin D

Interacts with
715 drugs
1000 IU per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
100 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

Enriched Omega-3 Blend

2300 mg per serving

Other (inactive) ingredients: Enriched Krill Omega-3 Blend, Capsule Shell, Beeswax, CoQ10, Proprietary LemonLock Freshness System, Astaxanthin extract, Cholecalciferol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Krill Omega 10X with CoQ10 by Purity Products Drug Interactions

Want to check YOUR meds against Krill Omega 10X with CoQ10?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,008Drugs
1,008 Moderate

Ingredients driving the most interactions

Vitamin D 715
natural Astaxanthin 671
Omega-3 Fatty Acids 375
Coenzyme Q10 198

Individual Drug Interactions

The ingredients in Krill Omega 10X with CoQ10 interact with 1,008 drugs. Click any drug to see the details.

4 of the 6 ingredients in Krill Omega 10X with CoQ10 interact with drugs. Each result below shows which ingredient is responsible. Vitamin D natural Astaxanthin Omega-3 Fatty Acids Coenzyme Q10

Each ingredient & the kinds of drugs it affects

For each ingredient in Krill Omega 10X with CoQ10 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D8 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D full monograph & interactions

natural Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
natural Astaxanthin full monograph & interactions

Omega-3 Fatty Acids3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.

Likelihood Probable Evidence B
Omega-3 Fatty Acids full monograph & interactions

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Krill Omega 10X with CoQ10, from the product label.

Purity Products

See all Purity Products products
Name
Purity Products
Pharmacist Counseling Corner

Krill Omega 10X with CoQ10 by Purity Products: Common Questions

Does Krill Omega 10X with CoQ10 by Purity Products interact with any medications?
Yes. Based on its ingredients, Krill Omega 10X with CoQ10 has a known interaction with 1,008 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Krill Omega 10X with CoQ10 contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Vitamin D at recommended doses is often used in pregnancy under a doctor's care. CoQ10 and the omega-3s haven't been studied well enough in pregnancy and breastfeeding — there isn't enough data to know either way. Astaxanthin should be avoided during pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What are the omega-3s in krill oil, and why would I take them?
Krill omega-3s contain eicosapentaenoic acid and docosahexaenoic acid — two fatty acids your body doesn't make on its own. They're bonded to phospholipids, which may help your body absorb them better than fish oil forms. Many people take omega-3s for heart and brain health, though the evidence varies by condition.
What does CoQ10 do in this product?
Coenzyme Q10 is a compound your cells make naturally to produce energy. Levels drop with age and with certain medications. It's likely effective if you're deficient in it, and possibly effective for migraines, fibromyalgia, heart failure, and diabetic nerve pain. The evidence is strongest for deficiency itself.
What's astaxanthin, and does it actually work?
Astaxanthin is a red pigment with antioxidant effects. We don't have reliable evidence yet that it works for aging skin, macular degeneration, cognitive decline, or other uses people claim for it. It's generally well tolerated, but long-term safety data are limited.
What side effects should I watch for?
CoQ10 may cause mild stomach upset, diarrhea, or nausea in less than 1% of people. Astaxanthin can cause abdominal discomfort, diarrhea, or red-colored stools. High-dose vitamin D over time can lead to toxicity with symptoms like nausea, weakness, kidney problems, and high blood calcium. Start with the recommended dose and don't exceed it.
Is this safe to take with my other supplements?
We can't check that without knowing what else you're taking. Use the interaction checker on this page — it'll search your full list against all three ingredients we have data for. If you take any prescription medications, that's especially important.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Krill Omega 10X with CoQ10 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Krill Omega 10X with CoQ10 label
Go deeper

The Full Monographs Behind Krill Omega 10X with CoQ10’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

Docosahexaenoic Acid (dha)

Interacts with 375 drugs

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...

Read the full Docosahexaenoic Acid (dha) monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Krill Omega 10X with CoQ10's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 118 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Docosahexaenoic Acid (dha) 49 references
  1. Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
  2. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  3. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  4. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  5. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  6. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  7. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  8. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  9. Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
  10. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
  11. Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
  12. Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
  13. Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
  14. Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
  15. Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
  16. Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
  17. Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Supplementation with docosahexaenoic acid in the last trimester of pregnancy: maternal-fetal biochemical findings. J Perinat Med 2004;32:132-6.
  18. Montgomery C, Speake BK, Cameron A, et al. Maternal docosahexaenoic acid supplementation and fetal accretion. Br J Nutr 2003;90:135-45. DOI
  19. Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Pediatr Res 2005;58:235-42. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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