L-5-MTHF Ingredients & Drug Interactions
What is this page for?
First and foremost: checking L-5-MTHF against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-5-MTHF is a dietary supplement by Adaptogen Research with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-5-MTHF by Adaptogen Research
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Folate” is listed as a grouped ingredient — the label gives one combined amount (1,000 mcg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-5-MTHF, straight from the product label.
| Brand | Adaptogen Research |
|---|---|
| Barcode (UPC) | 0612524953689 |
| Net contents | 120 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 22, 2021 |
| DSLD ID | 247064 |
| Product type | Vitamin |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-5-MTHF by Adaptogen Research, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Folate | 1000 mcg | 250% |
| Quatrefolic (6S)-5-Methyltetrahydrofolate Glucosamine Salt | 2000 mcg | -- |
Other ingredients: Spinach juice powder, Microcrystalline Cellulose, Cellulose, L-Leucine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Made with Non-GMO ingredients Does not contain gluten
Notice: Color, size or shape may appear different between lots.
Manufactured in a GMP Registered Facility in the USA.
Formula
Natural S-Isomer
L-5-MTHF is the natural, biologically active form of folate. It offers the benefits of optimal folate supplementation without the potential risks associated with chronic exposure to unmetabolized synthetic folic acid.
Quatrefolic
FDA Statement of Identity
Dietary Supplement
General Statements
Professional Use Only
Dr. Julia Dmitriva Digitally signed by Dr. Julia Dmitriva DN: cn-Dr. Julia Dmitriva, o, ou, [email protected], c-US Date: 2016-09-16 09:44:31 -06'00'
Seals/Symbols
Guaranteed GMP Compliant Products
Precautions
Report any adverse reactions to 302-213-0030
Keep out of reach of children.
Storage
Store at room temperature.
Suggested/Recommended/Usage/Directions
Recommended Use: As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.
Brand IP Statement(s)
Quatrefolic is covered by U.S. Patent No. 7,947,662 and is a registered trademark of Gnosis S.p.A.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-5-MTHF by Adaptogen Research label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-5-MTHF by Adaptogen Research
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Folate
- › Quatrefolic (6S)-5-Methyltetrahydrofolate Glucosamine Salt
Other (inactive) ingredients: Spinach juice powder, Microcrystalline Cellulose, Cellulose, L-Leucine. These complete the product’s ingredient list but are not active constituents.
L-5-MTHF by Adaptogen Research Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-5-MTHF. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-5-MTHF, from the product label.
Adaptogen Research
See all Adaptogen Research products- Name
- Adaptogen Research
- Street Address
- 625 Barksdale Road, Suite 113
- City
- Newark
- State
- DE
- ZipCode
- 19711
- Phone Number
- 302-213-0030
L-5-MTHF by Adaptogen Research: Common Questions
Does L-5-MTHF by Adaptogen Research interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-5-MTHF is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
L-5-MTHF's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC