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Dietary supplement

L-Carnosine 200 mg Ingredients & Drug Interactions

by Kirkman

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Carnosine 200 mg is a dietary supplement by Kirkman with 1 active ingredient. Its ingredients are commonly taken for anti-aging and general wellness, exercise performance and muscle support, brain and cognitive health.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Carnosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Carnosine 200 mg by Kirkman

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-Carnosine, a naturally occurring compound made from two amino acids. The capsule itself is made from plant cellulose, and the inactive ingredients are cellulose and silicon dioxide—all standard capsule materials.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Carnosine product and its label doesn't state a use — see Carnosine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for L-Carnosine is thin. It's rated possibly ineffective for autism spectrum disorder.

For age-related cognitive decline, Alzheimer's disease, athletic performance, cataracts, and general cognitive impairment, there isn't enough reliable evidence yet to say whether it works or doesn't.

The evidence, ingredient by ingredient Carnosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Carnosine is generally well tolerated in short-term studies, though long-term safety data are limited. Some people have reported decreased appetite, dry mouth, small weight changes, foot and joint pain, and in rare cases, pneumonia.

The safety data advise against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations.

Side effects, ingredient by ingredient Carnosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Carnosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (medication that lowers blood sugar), flag this product with your doctor or pharmacist before starting. Carnosine may lower blood glucose on its own, which could raise the risk of low blood sugar when combined with your diabetes medication.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-Carnosine is most relevant if you're curious about autism spectrum disorder, though current evidence doesn't support it for that use. If you take antidiabetes medications, you'll want to talk with your doctor or pharmacist before starting—there's a moderate interaction risk involving blood sugar control.

For any other reason you're considering it, the evidence is still being built.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Carnosine 200 mg, straight from the product label.

Brand Kirkman
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2013
DSLD ID 24641
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Carnosine 200 mg by Kirkman, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
90
IngredientAmount% DV
L-Carnosine200 mg--

Other ingredients: Cellulose, Plant, Silicon Dioxide, Plant Cellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

HYPOALLERGENIC

Formulation

FREE OF: Sugar, starch, soy, wheat, casein, gluten, milk, corn, preservatives, yeast, gelatin, flavorings, or colorings.

CASEIN & GLUTEN FREE

Storage

IMPORTANT: STORE IN A COOL DRY PLACE AND TIGHTLY CAPPED.

Precautions

KEEP OUT OF THE REACH OF CHILDREN.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

SUGGESTED USE: 1-4 capsules daily or as directed by a physician.

General

277/90

General Statements

Best Used By: May 2013

(503)694-1600

See for yourself

L-Carnosine 200 mg by Kirkman label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Carnosine 200 mg by Kirkman

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

L-Carnosine

Interacts with
86 drugs
200 mg per serving

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is so...

L-Carnosine monograph & interactions

Other (inactive) ingredients: Cellulose, Plant, Silicon Dioxide, Plant Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Carnosine 200 mg by Kirkman Drug Interactions

Want to check YOUR meds against L-Carnosine 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Carnosine 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Carnosine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking carnosine with antidiabetes drugs might increase the risk of hypoglycemia.
Some, but not all, preliminary clinical research shows that carnosine might reduce fasting blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for L-Carnosine 200 mg, from the product label.

Kirkman

See all Kirkman products
Name
Kirkman
City
Lake Oswego
State
OR
ZipCode
97035
Phone Number
(800) 245-8282
Web Address
www.kirkmangroup.com
Pharmacist Counseling Corner

L-Carnosine 200 mg by Kirkman: Common Questions

Does L-Carnosine 200 mg by Kirkman interact with any medications?
Yes. Based on its ingredients, L-Carnosine 200 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Carnosine 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take L-Carnosine if I'm pregnant or breastfeeding?
The safety data advise against it. There isn't enough information to know whether it's safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about your situation before deciding.
What side effects have been reported?
Some people have had decreased appetite, dry mouth, small weight changes, foot and joint pain, and rarely pneumonia. Keep in mind that long-term safety data are limited, so we don't know all the possible effects from extended use.
Does L-Carnosine actually work for autism or cognitive decline?
For autism spectrum disorder, current evidence suggests it's likely not effective. For Alzheimer's disease, age-related cognitive decline, cataracts, and general cognitive impairment, there isn't enough reliable evidence yet to say either way.
Why does this product interact with diabetes medications?
Preliminary research shows carnosine may lower fasting blood glucose levels on its own. If you're already taking a drug that lowers blood sugar, adding carnosine could tip you toward low blood sugar (hypoglycemia). Your doctor or pharmacist can help you manage this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Carnosine 200 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Carnosine 200 mg label
Go deeper

The Full Monographs Behind L-Carnosine 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Carnosine 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Carnosine 5 references
  1. Chengappa KN, Turkin SR, DeSanti S, et al. A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia. Schizophr Res 2012;142(1-3):145-52. PubMed
  2. Karkabounas S, Papadopoulos N, Anastasiadou C, et al. Effects of a-lipoic Acid, carnosine, and thiamine supplementation in obese patients with type 2 diabetes mellitus: A randomized, double-blind study. J Med Food. 2018;21(12):1197-1203.
  3. Peng W, Mao P, Liu L, et al. Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: a systematic review and meta-analysis of long-term randomized controlled trials. Complement Ther Med 2020;48:102241. PubMed
  4. Siriwattanasit N, Satirapoj B, Supasyndh O. Effect of oral carnosine supplementation on urinary TGF-ß in diabetic nephropathy: a randomized controlled trial. BMC Nephrol 2021;22(1):236. PubMed
  5. Sureshkumar K, Durairaj M, Srinivasan K, et al. Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis. Front Biosci (Landmark Ed) 2023;28(1):18. PubMed

See these in context on the Carnosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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