L-Methionine Ingredients & Drug Interactions
by NutriCology
What is this page for?
First and foremost: checking L-Methionine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Methionine is a dietary supplement by NutriCology with 1 active ingredient. Its ingredients are commonly taken for acetaminophen (tylenol) overdose support, liver health, urinary tract acidification.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-Methionine by NutriCology
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: L-Methionine, an amino acid your body makes naturally and also gets from protein-rich foods like meat, fish, eggs, and dairy. The capsule also holds inactive ingredients — microcrystalline cellulose, hydroxypropyl methylcellulose, and L-leucine — which are fillers and binders that help hold the capsule together.
Does it work?
Not established
The evidence we hold rates L-Methionine as possibly effective for reducing the risk of neural tube birth defects (birth defects of the brain or spine). For acetaminophen poisoning, hay fever, asthma, and colorectal cancer, the evidence is either not reliable enough or too sparse to rate — we just don't have the data to say whether it works for those uses.
How safe is it?
Well-documented data
L-Methionine from food is well tolerated. At supplement doses, though, caution applies: the safety data advises using it under medical guidance.
The most common side effects in trials were dizziness, drowsiness, low blood pressure (hypotension), irritability, and vomiting. High-dose methionine may also raise homocysteine levels in the blood, a risk factor for vascular disease, though one study in people with type 2 diabetes and heart disease history did not see this effect.
Rare serious effects include brain swelling and liver-related confusion. During pregnancy and breastfeeding, food amounts are expected to be fine, but the safety data rates supplement doses as likely safe.
Still, there's room for caution: supplement safety during pregnancy and breastfeeding has not been fully proven. Talk with your doctor or pharmacist before taking this product if you're pregnant or nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for L-Methionine. Even so, mention this supplement to your doctor or pharmacist before you start taking it, especially if you have a history of heart disease, vascular problems, or low blood pressure.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
L-Methionine may be worth considering if you're thinking about neural tube birth defect prevention, though talk with your doctor about whether it's right for you. If you have low blood pressure, a history of heart or vascular disease, or are pregnant or nursing, check with your doctor or pharmacist before starting.
No interactions are documented for this ingredient, but mention it to your pharmacist along with any other medications you take.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Methionine, straight from the product label.
| Brand | NutriCology |
|---|---|
| Barcode (UPC) | 713947506107 |
| Net contents | 100 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2020 |
| DSLD ID | 235206 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Methionine by NutriCology, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Methionine | 500 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, L-Leucine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
L-methionine, an essential sulfur-bearing amino acid. Free form amino acid, high purity, well tolerated.
Suggested/Recommended/Usage/Directions
Suggested Use As a dietary supplement, 1 capsule one to three times daily between meals, or as directed by a healthcare practitioner.
Storage
Keep in a cool, dry place, tightly capped.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
NutriCology Innovative Nutrition
Formulation
Liver and energy support Hypoallergenic
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Methionine by NutriCology label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Methionine by NutriCology
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
L-Methionine
No knowninteractions
Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a norma...
L-Methionine monograph & interactionsOther (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, L-Leucine. These complete the product’s ingredient list but are not active constituents.
L-Methionine by NutriCology Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-Methionine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-Methionine, from the product label.
NutriCology
See all NutriCology products- Name
- NutriCology
- City
- South Salt Lake
- State
- UT
- ZipCode
- 84115
- Phone Number
- 800.545.9960
- Web Address
- www.nutricology.com
L-Methionine by NutriCology: Common Questions
Does L-Methionine by NutriCology interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will L-Methionine help prevent birth defects?
Is this supplement safe to take while pregnant?
What are the main side effects?
Can I take this if I have heart disease or low blood pressure?
What is L-Methionine and why is it in the product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Methionine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Methionine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Methionine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Methionine 12 references
- La Vecchia C, Negri E, Franceschi S, Decarli A. Case-control study on influence of methionine, nitrite, and salt on gastric carcinogenesis in northern Italy. Nutr Cancer 1997;27:65-8. PubMed
- Btaiche IF, Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002;22:188-211.. PubMed
- Cottington EM, LaMantia C, Stabler SP, et al. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol 2002;22:1046-50.. PubMed
- Anon. Should methionine be added to paracetamol formulations? Drug Ther Perspect 1997;10:11-3. DOI
- Smulders, Y. M., Rakic, M., Slaats, E. H., Treskes, M., Sijbrands, E. J., Odekerken, D. A., Stehouwer, C. D., and Silberbusch, J. Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and c
- McAuley, D. F., Hanratty, C. G., McGurk, C., Nugent, A. G., and Johnston, G. D. Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. J.Toxicol.Clin.Toxicol. 1999;37(4):435-440. PubMed
- Hanratty, C. G., McGrath, L. T., McAuley, D. F., Young, I. S., and Johnston, G. D. The effects of oral methionine and homocysteine on endothelial function. Heart 2001;85(3):326-330. PubMed
- Ward, M., McNulty, H., McPartlin, J., Strain, J. J., Weir, D. G., and Scott, J. M. Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study. Int.J.Vitam.Nutr.Res. 2001;71(1):82-86. PubMed
- Yaghmai, R., Kashani, A. H., Geraghty, M. T., Okoh, J., Pomper, M., Tangerman, A., Wagner, C., Stabler, S. P., Allen, R. H., Mudd, S. H., and Braverman, N. Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient
- Talukdar R, Murthy HV, Reddy DN. Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis. Pancreatology 2015;15(2):136-44. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005. Available at: https://doi.org/10.17226 DOI
- Khairan P, Sobue T, Eshak ES, et al. Association of B Vitamins and Methionine Intake with the Risk of Gastric Cancer: The Japan Public Health Center-based Prospective Study. Cancer Prev Res (Phila) 2022;15(2):101-110. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC