No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Ornithine 500 mg Ingredients & Drug Interactions

by Solgar

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Ornithine 500 mg is a dietary supplement by Solgar with 1 active ingredient. Its ingredients are commonly taken for athletic performance and recovery, reducing fatigue, sleep and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Ornithine 500 mg by Solgar

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-Ornithine, an amino acid, at 500 mg per capsule. The rest — vegetable cellulose, microcrystalline cellulose, vegetable magnesium stearate, silica, and stearic acid — are inactive ingredients that make up the capsule and help it hold together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Ornithine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Ornithine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).

L-Ornithine is possibly effective for athletic performance. For other uses listed — dry skin, insomnia, and periodontitis (gum inflammation) — the evidence isn't strong enough to say whether it works.

If you're taking it for one of those reasons, the data we hold doesn't support a clear benefit.

The evidence, ingredient by ingredient Ornithine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Ornithine is generally well tolerated in the short term, but we don't have much data on what happens if you take it for years. The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know it's safe.

If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before starting it.

Side effects, ingredient by ingredient Ornithine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-Ornithine. Still, run your medications through the tool on this page and talk with your doctor or pharmacist before adding any new supplement to your routine.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and some safety-information gaps remain.

If you're an athlete looking to support performance, L-Ornithine may be worth a try. Anyone pregnant, breastfeeding, or taking it long-term should check in with their own doctor or pharmacist first.

No interactions are documented for this ingredient, but that's not a guarantee none exist — your healthcare provider knows your full picture best.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Ornithine 500 mg, straight from the product label.

Brand Solgar
Barcode (UPC) 033984020603
Net contents 50 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218572
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Ornithine 500 mg by Solgar, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
033984020603
IngredientAmount% DV
L-Ornithine500 mg--

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silica, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

L-Ornithine is an intermediate compound involved in the synthesis of L-Arginine in the body. This formulation provides Free Form L-Ornithine to promote optimal absorption and assimilation.

Solgar's KOF-K certification #K-1250

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

2012 Solgar, Inc.

General Statements

Solgar since 1947

Formulation

Free form

Gluten, wheat & dairy free

Suitable for vegetarians

Free of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives and color.

Seals/Symbols

K Parve (Kosher)

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement for adults, take one (1) vegetable capsule up to two times daily, between meals, or as directed by a healthcare practitioner.

Precautions

If you are pregnant, nursing, taking any medications or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement.

Discontinue use and consult your healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

Do not use if outer bottle seal is missing or damaged.

Storage

Store at room temperature.

See for yourself

L-Ornithine 500 mg by Solgar label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Ornithine 500 mg by Solgar

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

L-Ornithine

No known
interactions
500 mg per serving Form: L-Ornithine Hydrochloride

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement fo...

L-Ornithine monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silica, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Ornithine 500 mg by Solgar Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Ornithine 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Ornithine 500 mg, from the product label.

Solgar

See all Solgar products
Name
Solgar, Inc.
Street Address
500 Willow Tree Road
City
Leonia
State
NJ
ZipCode
07605
Phone Number
1-877-765-4274
Web Address
www.solgar.com
Pharmacist Counseling Corner

L-Ornithine 500 mg by Solgar: Common Questions

Does L-Ornithine 500 mg by Solgar interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Ornithine 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Ornithine 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does L-Ornithine actually work for athletic performance?
The evidence suggests it's possibly effective, which means there's some support for it but it's not proven. If you're an athlete, it may be worth a trial, but results can vary from person to person.
Can I take this while I'm pregnant?
The safety data advises against it — there isn't enough information to know whether it's safe during pregnancy. Talk with your doctor before taking it if you're pregnant or planning to be.
Can I take this while breastfeeding?
The safety data advises against it during breastfeeding because the data isn't there to say it's safe. Check with your doctor or pharmacist before starting it if you're nursing.
What are the side effects?
We don't have adverse effects listed in our data, and it's generally well tolerated in the short term. Long-term safety is less clear, so if you're taking it for months, keep an eye on how you feel.
Is this just one ingredient?
Yes — it's L-Ornithine at 500 mg. The capsule itself is made of vegetable cellulose and a few other inactive binders and stabilizers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Ornithine 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Ornithine 500 mg label
Go deeper

The Full Monographs Behind L-Ornithine 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Ornithine 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ornithine 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the Ornithine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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