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Dietary supplement

Lactobacillus Gasseri 12 Billion CFU Ingredients & Drug Interactions

by SuperSmart

Lactobacillus Gasseri 12 Billion CFU label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lactobacillus Gasseri 12 Billion CFU against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lactobacillus Gasseri 12 Billion CFU is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for digestive health, weight and belly fat management, vaginal and urinary health.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus gasseri CNCM I-5076. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lactobacillus Gasseri 12 Billion CFU by SuperSmart

Ask about any prescription or over-the-counter medication and we check it for interactions with Lactobacillus Gasseri 12 Billion CFU by SuperSmart — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lactobacillus Gasseri 12 Billion CFU by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Lactobacillus gasseri CNCM I-5076, a live bacterial culture (probiotic) at 12 billion colony-forming units per capsule. The capsule itself contains acacia gum as an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lactobacillus Gasseri product and its label doesn't state a use — see Lactobacillus Gasseri's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that Lactobacillus gasseri works reliably for hay fever, aspirin-related stomach damage, asthma, bacterial vaginosis, the common cold, or diarrhea — the data shows insufficient reliable evidence for all of these. That doesn't mean it won't help; it means we don't have solid proof yet.

The evidence, ingredient by ingredient Lactobacillus Gasseri

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus gasseri is generally well tolerated in healthy adults, but safety data is limited and incomplete. Some people should avoid it — especially those with compromised immune systems or those at risk of infection — because live bacterial supplements carry a theoretical concern: in rare cases, these bacteria have been found in serious infections like bacteremia (bacteria in the bloodstream), sepsis, endocarditis (heart infection), and meningitis.

These cases usually involve bacteria that moved from their normal home in the body (like the mouth) to somewhere they shouldn't be. Because safety information is limited, talk with your doctor before using this product.

Side effects, ingredient by ingredient Lactobacillus Gasseri

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs (Moderate severity) — antibiotics can kill the live organisms in this supplement and reduce how well it works. Space your antibiotic and this supplement several hours apart, and ask your pharmacist for the best timing.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic is a single-strain live culture with limited safety data and no established effectiveness for the conditions listed. If you take antibiotics, you'll need to space them apart from this supplement.

Anyone with a weakened immune system or serious health condition should check with their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactobacillus Gasseri 12 Billion CFU, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003826460
Net contents 60 Drcaps Hypromellose Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 315575
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactobacillus Gasseri 12 Billion CFU by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
5453003826460
IngredientAmount% DV
Lactobacillus gasseri CNCM I-5076200 mg--

Other ingredients: Acacia Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended use: Adults. Take 2 capsules per day.

Formula

Each capsule contains 100 mg Lactobacillus gasseri CNCM I-5076 (6 billion micro-organisms).

Lactobacillus gasseri 12 Billion CFU Per Day

Storage

Precautions: Keeps better when refrigerated.

Store away from direct light, heat and humidity.

Precautions

Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.

Keep out of childrens' reach.

As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lactobacillus Gasseri 12 Billion CFU by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lactobacillus Gasseri 12 Billion CFU label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lactobacillus Gasseri 12 Billion CFU by SuperSmart

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Lactobacillus gasseri CNCM I-5076

Interacts with
182 drugs
200 mg per serving

Lactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Ear...

Lactobacillus gasseri CNCM I-5076 monograph & interactions

Other (inactive) ingredients: Acacia Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactobacillus Gasseri 12 Billion CFU by SuperSmart Drug Interactions

Want to check YOUR meds against Lactobacillus Gasseri 12 Billion CFU?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus gasseri CNCM I-5076 182

Individual Drug Interactions

The ingredients in Lactobacillus Gasseri 12 Billion CFU interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lactobacillus Gasseri 12 Billion CFU interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus gasseri CNCM I-5076

Each ingredient & the kinds of drugs it affects

For each ingredient in Lactobacillus Gasseri 12 Billion CFU with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus gasseri CNCM I-50761 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus gasseri CNCM I-5076 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lactobacillus Gasseri 12 Billion CFU, from the product label.

SuperSmart

See all SuperSmart products
Name
SN Worldwide Unipessoal, LDA
Street Address
Avenida Do Infante 66 Edificio Quinta Avenida 1 C
City
Funchal
ZipCode
9000-015
Pharmacist Counseling Corner

Lactobacillus Gasseri 12 Billion CFU by SuperSmart: Common Questions

Does Lactobacillus Gasseri 12 Billion CFU by SuperSmart interact with any medications?
Yes. Based on its ingredients, Lactobacillus Gasseri 12 Billion CFU has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lactobacillus Gasseri 12 Billion CFU contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic while I'm on antibiotics?
You can, but timing matters. Antibiotics can kill the live bacteria in this supplement, which makes it less effective. Talk to your pharmacist about spacing them several hours apart — don't take them at the same time.
Is this supplement proven to treat diarrhea or improve gut health?
The evidence we hold doesn't establish that it works reliably for diarrhea or the other conditions listed. That's not a verdict against it — just that the data available to us isn't solid enough to say yes or no.
Is it safe if I have a weakened immune system?
No — you should avoid this product. Because it contains live bacteria, there's a theoretical risk they could cause serious infection in people with compromised immunity. Talk to your doctor before using any live probiotic supplement if your immune system is weak.
What does 12 billion CFU mean?
CFU stands for colony-forming units — it's a way to count live bacterial cells. This product delivers 12 billion of them per capsule.
Can I take this while pregnant or breastfeeding?
The safety data we have doesn't tell us whether this is safe during pregnancy or lactation. Talk with your doctor or pharmacist for personalized advice — they can help you weigh the benefits and risks based on your own situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactobacillus Gasseri 12 Billion CFU is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactobacillus Gasseri 12 Billion CFU label
Go deeper

The Full Monographs Behind Lactobacillus Gasseri 12 Billion CFU’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Gasseri

Interacts with 182 drugs

Lactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Early research suggests it may help with di...

Read the full Lactobacillus Gasseri monograph →
Sources

Sources & How We Checked

Lactobacillus Gasseri 12 Billion CFU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
  3. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  4. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  5. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  6. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  7. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  8. Ramos-Coria D, Canto-Losa J, Carrillo-Vázquez D, Carbajal-Morelos L, Estrada-León R, Corona-Rodarte E. Lactobacillus gasseri liver abscess and bacteremia: a case report. BMC Infect Dis 2021;21(1):518. PubMed
  9. Elikowski W, Malek-Elikowska M, Lisiecka M, Bodora A, Wisniewska K, Oko-Sarnowska Z. Lactobacillus gasseri endocarditis on the aortic valve bioprosthesis - a case report. Pol Merkur Lekarski 2017;43(257):220-223.
  10. Esquibel A, Dababneh AS, Palraj BR. Lactobacillus gasseri causing bilateral empyema. Case Rep Infect Dis 2017;2017:4895619.
  11. Tleyjeh IM, Routh J, Qutub MO, Lischer G, Liang KV, Baddour LM. Lactobacillus gasseri causing Fournier's gangrene. Scand J Infect Dis 2004;36(6-7):501-3. PubMed
  12. Dickgiesser U, Weiss N, Fritsche D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 1984;12(1):14-6. PubMed

See these in context on the Lactobacillus Gasseri monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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