Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Lactobacillus Rhamnosus GG 10 Billion CFU Ingredients & Drug Interactions

by SuperSmart

Capsule Category: Other Combinations
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Lactobacillus Rhamnosus GG 10 Billion CFU is a dietary supplement by SuperSmart with 2 active ingredients. Its ingredients are commonly taken for constipation and regularity, prebiotic gut health, blood sugar support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Inulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains two active ingredients: LifeinU and inulin. Inulin is a soluble fiber that may support digestive health and blood sugar balance.

The product also contains several inactive ingredients — hypromellose, acacia gum, and white rice flour — which are fillers and capsule materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Inulin's overall clinical evidence instead.

Moderate

Some clinical evidence supports Inulin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Constipation — rated "Possibly Effective" (Natural Medicines).
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).
  • On file: Obesity — rated "Possibly Effective" (Natural Medicines).

According to the data we hold, inulin is possibly effective for obesity, constipation, and diabetes. The evidence for inulin's use in nonalcoholic fatty liver disease and iron deficiency anemia is too limited to rate.

We don't have effectiveness information on file for LifeinU.

The evidence, ingredient by ingredient Inulin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inulin is generally well tolerated, but it commonly causes gas, bloating, constipation, diarrhea, and cramping — especially at higher doses over 30 grams. These side effects are most likely when you first start taking it.

Rarely, anaphylaxis (a severe allergic reaction) has been reported after consuming foods high in inulin. Inulin is rated likely safe in pregnancy and lactation, but talk to your doctor before using a concentrated supplement if you're pregnant or nursing.

Side effects, ingredient by ingredient Inulin

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inulin.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs, check them against the interaction tool on this page before you start. Inulin may theoretically raise the risk of low blood sugar, though the evidence is mixed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Only minor medication interactions are documented, and safety information is well characterized.

This product may help with constipation, blood sugar balance, or weight management, but inulin can cause digestive upset. If you take diabetes medications, check your exact drugs with the tool below before starting — inulin may theoretically increase the risk of low blood sugar.

Talk to your pharmacist if you have questions about how it fits with your other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactobacillus Rhamnosus GG 10 Billion CFU, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003827276
Net contents 60 Delayed Release Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 339853
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
5453003827276
IngredientAmount% DV
LifeinU100 mg--
Inulin250 mg--

Other ingredients: Hypromellose, Acacia Gum, White Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

LifeinU L. rhamnosus GG is trademark of Lesaffre, France.

FDA Statement of Identity

Dietary Supplement

Formula

Lactobacillus rhamnosus GG 10 Billion CFU Per Day

Formulation

Guarantees: Vegan, non-GMO, gluten free, soy free, dairy free.

Guarantees: Vegan, non-GMO, gluten free, soy free, dairy free. No coloring, preservatives or flavorings.

FDA registered lab, Good Manufacturing Practice, Made in USA.

Suggested/Recommended/Usage/Directions

Directions: Adults. As a supplement, take 2 capsules daily before meals or as directed by the practitioner.

Precautions

Do not exceed the recommended daily dose.

Keep out of reach of children.

Consult a healthcare provider before using this product if pregnant, breastfeeding, or having health concerns.

Tamper evident: Do not use if seal under cap is broken or missing.

Storage

Cautions: Better kept refrigerated. Store away from direct light, heat and humidity.

See for yourself

Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

LifeinU

100 mg per serving Form: Lactobacillus rhamnosus GG

Inulin

Interacts with
86 drugs
250 mg per serving Form: Chicory, Powder

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements an...

Inulin monograph & interactions

Other (inactive) ingredients: Hypromellose, Acacia Gum, White Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart Drug Interactions

Want to check YOUR meds against Lactobacillus Rhamnosus GG 10 Billion CFU?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Minor

Ingredients driving the most interactions

Inulin 86

Each ingredient & the kinds of drugs it affects

For each ingredient in Lactobacillus Rhamnosus GG 10 Billion CFU with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inulin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for Lactobacillus Rhamnosus GG 10 Billion CFU, from the product label.

SuperSmart

See all SuperSmart products
Name
SuperSmart USA LLC
City
Miami
State
FL
ZipCode
33130
Phone Number
1 (786) 522-3907
Web Address
us.SuperSmart.com
Pharmacist Counseling Corner

Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart: Common Questions

Does Lactobacillus Rhamnosus GG 10 Billion CFU by SuperSmart interact with any medications?
Yes. Based on its ingredients, Lactobacillus Rhamnosus GG 10 Billion CFU has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lactobacillus Rhamnosus GG 10 Billion CFU contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me gas and bloating?
It's common, especially when you first start taking it or at higher doses. Most people report bloating, flatulence, constipation, or diarrhea. Stick with a lower dose at first and see how your body responds.
Is it safe to take while I'm pregnant or nursing?
Inulin is rated likely safe in pregnancy and lactation based on the data we hold. Still, talk to your doctor or pharmacist before using a concentrated supplement — food amounts are one thing, but supplement doses are less well studied.
Does this actually work for constipation?
Inulin is possibly effective for constipation according to the evidence. Since it's a soluble fiber, it should help, but results vary from person to person.
Can I take this if I have diabetes?
Inulin may help with blood sugar control, but it could theoretically increase the risk of low blood sugar if you're already on diabetes medication. Check your specific drugs with the tool on this page, and talk to your doctor before adding it.
What's LifeinU?
We don't hold interaction or effectiveness data for LifeinU, so we can't tell you much about it. Your pharmacist or the product manufacturer can give you more details about that ingredient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactobacillus Rhamnosus GG 10 Billion CFU is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactobacillus Rhamnosus GG 10 Billion CFU label
Go deeper

The Full Monographs Behind Lactobacillus Rhamnosus GG 10 Billion CFU’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lactobacillus Rhamnosus GG 10 Billion CFU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inulin 17 references
  1. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
  2. Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  5. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
  6. Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
  7. Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
  8. Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
  9. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
  10. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
  13. Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
  14. Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
  15. Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
  16. Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
  17. Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed

See these in context on the Inulin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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