Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Lactobacillus Tablets Ingredients & Drug Interactions

by Marlex Pharmaceuticals

Lactobacillus Tablets label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lactobacillus Tablets against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lactobacillus Tablets is a dietary supplement by Marlex Pharmaceuticals with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Lactobacillus bulgaricus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lactobacillus Tablets by Marlex Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Lactobacillus Tablets by Marlex Pharmaceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lactobacillus Tablets by Marlex Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active probiotic ingredients: Lactobacillus acidophilus and Lactobacillus bulgaricus. Both are live bacterial cultures that work in your gut to support digestive and immune health.

The tablet also includes several inactive ingredients—dicalcium phosphate, silicon dioxide, croscarmellose sodium, microcrystalline cellulose, magnesium stearate, and stearic acid—which serve as binders, flow agents, and capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

The evidence for Lactobacillus acidophilus is strongest for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, where it's rated Possibly Effective. It's rated Possibly Ineffective for atopic disease and has Insufficient Reliable Evidence for acute respiratory distress syndrome.

Lactobacillus bulgaricus has Insufficient Reliable Evidence for all the conditions in our data—acne, allergic rhinitis, antibiotic-associated diarrhea, asthma, nonalcoholic fatty liver disease, and common cold. This means we don't yet have solid evidence to say whether it helps for these uses.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Delbrueckii

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Lactobacillus acidophilus and Lactobacillus bulgaricus are generally well tolerated in healthy adults and children. However, people who are very ill or have weakened immune systems should be cautious, since live probiotic bacteria can theoretically cause serious infections—bacteremia, sepsis, abscess, or endocarditis—though these cases are rare and usually involve bacteria that naturally occur in your body.

Some people taking these probiotics may experience mild gastrointestinal side effects like bloating, flatulence, abdominal pain, or diarrhea, but such events are uncommon. For pregnancy, Lactobacillus acidophilus is rated Possibly Safe, but data on supplement use during pregnancy are limited; talk with your doctor before starting if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Delbrueckii

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Lactobacillus Delbrueckii.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use any antibiotic medications—these are Moderate-severity interactions that require timing the doses apart so the antibiotics don't kill the live cultures in the tablets.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're dealing with irritable bowel syndrome, antibiotic-associated diarrhea, or certain infections like bacterial vaginosis or H. pylori, Lactobacillus acidophilus in this product may be worth trying. Be especially careful if you're taking antibiotics—space them out so the probiotic isn't wiped out—and mention this product to your doctor or pharmacist if you're very ill, immunocompromised, pregnant, or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactobacillus Tablets, straight from the product label.

Brand Marlex Pharmaceuticals
Barcode (UPC) 310135705504
Net contents 50 Tablet(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 263345
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactobacillus Tablets by Marlex Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Tablet(s)
Maximum serving Sizes:
4 Tablet(s)
Servings per container
13
UPC/BARCODE
310135705504
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Sugar1 Gram(s)--
Lactobacillus acidophilus0.2 mg--
Lactobacillus bulgaricus0.2 mg--

Other ingredients: Dicalcium Phosphate, Silicon Dioxide, Colloidal, Croscarmellose Sodium, Microcrystalline Cellulose, Magnesium Stearate, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

NDC 10135-0705-50

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults, take four (4) tablets 3 to 4 times daily as dietary supplement. May be followed by a small amount of milk, fruit juice or water.

Precautions

Warning: Do not use if sensitive to milk products.

Keep out of reach of children.

Storage

Other information: Store in a cool, dry place at controlled room temperature 15-30 degrees C (59-86 degrees F)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lactobacillus Tablets by Marlex Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lactobacillus Tablets label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lactobacillus Tablets by Marlex Pharmaceuticals

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Tablet(s) Dosage formTablet Or Pill Servings per container13 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Lactobacillus acidophilus

Interacts with
182 drugs
0.2 mg per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus monograph & interactions

Lactobacillus bulgaricus

Interacts with
182 drugs
0.2 mg per serving

Lactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is g...

Lactobacillus bulgaricus monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Silicon Dioxide, Colloidal, Croscarmellose Sodium, Microcrystalline Cellulose, Magnesium Stearate, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactobacillus Tablets by Marlex Pharmaceuticals Drug Interactions

Want to check YOUR meds against Lactobacillus Tablets?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182
Lactobacillus bulgaricus 182

Individual Drug Interactions

The ingredients in Lactobacillus Tablets interact with 182 drugs. Click any drug to see the details.

2 of the 3 ingredients in Lactobacillus Tablets interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Lactobacillus bulgaricus

Each ingredient & the kinds of drugs it affects

For each ingredient in Lactobacillus Tablets with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions

Lactobacillus bulgaricus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus bulgaricus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lactobacillus Tablets, from the product label.

Marlex Pharmaceuticals

See all Marlex Pharmaceuticals products
Name
Marlex Pharmaceuticals, Inc.
City
New Castle
State
DE
ZipCode
19720
Pharmacist Counseling Corner

Lactobacillus Tablets by Marlex Pharmaceuticals: Common Questions

Does Lactobacillus Tablets by Marlex Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Lactobacillus Tablets has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lactobacillus Tablets contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with diarrhea I got after taking antibiotics?
Lactobacillus acidophilus in this product is rated Possibly Effective for antibiotic-associated diarrhea. However, you'll need to time it carefully: take your antibiotic on schedule, but separate it from this tablet by a few hours so the antibiotic doesn't kill off the beneficial bacteria.
Can I take this if I have a weakened immune system?
People who are very ill or immunocompromised should be cautious with live probiotic products like this one. Because it contains live bacteria, there's a theoretical risk of infection in that population. Talk with your doctor before starting.
What kind of side effects might I notice?
Most people tolerate these probiotics well. Some may experience mild digestive discomfort—bloating, gas, abdominal pain, or loose stools—but these are uncommon. A small number of trial participants taking probiotic combinations reported rash or itching, though it's unclear if those were from this ingredient specifically.
Is this safe to take during pregnancy?
Lactobacillus acidophilus is rated Possibly Safe in pregnancy, but data on supplement use during pregnancy are limited. Check with your doctor before starting to get personalized advice for your situation.
How long do I have to wait between taking my antibiotic and this probiotic?
The product facts don't specify an exact time interval. Ask your pharmacist or doctor how to space them—typically a few hours apart is standard practice—so the antibiotic doesn't reduce the probiotic's effectiveness.
Does Lactobacillus bulgaricus help with anything?
In our data, Lactobacillus bulgaricus has Insufficient Reliable Evidence for the conditions listed—acne, hay fever, antibiotic-associated diarrhea, asthma, fatty liver disease, and common cold—meaning we don't yet have solid evidence it works for those uses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactobacillus Tablets is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactobacillus Tablets label
Go deeper

The Full Monographs Behind Lactobacillus Tablets’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Lactobacillus Delbrueckii

Interacts with 182 drugs

Lactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy peo...

Read the full Lactobacillus Delbrueckii monograph →
Sources

Sources & How We Checked

Lactobacillus Tablets's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Delbrueckii 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
  8. Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
  9. Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.

See these in context on the Lactobacillus Delbrueckii monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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