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Dietary supplement

Lemon Balm Extract Ingredients & Drug Interactions

by Earthborn Elements

Lemon Balm Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lemon Balm Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lemon Balm Extract is a dietary supplement by Earthborn Elements with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lemon Balm extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lemon Balm Extract by Earthborn Elements

Ask about any prescription or over-the-counter medication and we check it for interactions with Lemon Balm Extract by Earthborn Elements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lemon Balm Extract by Earthborn Elements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 8, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains one active ingredient, lemon balm extract. Our data does not spell out its role in the product, but the lemon balm research we hold looks at cold sores, stress, and depression.

The only inactive ingredient listed is gelatin, which is used as the capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Lemon Balm's overall clinical evidence instead.

Moderate

Some clinical evidence supports Lemon Balm for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Herpes labialis (cold sores) — rated "Possibly Effective" (Natural Medicines).
  • On file: Depression — rated "Possibly Effective" (Natural Medicines).
  • On file: Stress — rated "Possibly Effective" (Natural Medicines).

Lemon balm is rated Possibly Effective for herpes labialis (cold sores), stress, and depression. That rating means the evidence is promising but not firm enough to be called effective.

These ratings come from the lemon balm research we hold, and they are not a guarantee that this capsule will work for any of these uses.

The evidence, ingredient by ingredient Lemon Balm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lemon balm is generally well tolerated for short-term use in most healthy adults, but high doses and long-term safety are not well studied. Oral use has been reported to cause dizziness and sedation, though these do not appear to occur more often than with placebo.

Research also found that using lemon balm with alcohol did not affect reaction time or cognitive performance. A case report describes a 25-year-old woman who developed a heart rhythm problem after using a different multi-ingredient product containing lemon balm.

It is unclear whether lemon balm caused it. For pregnancy, our safety data advises avoiding lemon balm unless your doctor advises otherwise, because there is not enough reliable safety data.

For breastfeeding, the data is limited, so use caution and talk with your doctor first.

Side effects, ingredient by ingredient Lemon Balm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lemon Balm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 264 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check these medication types before taking this product, worst severity first. CNS depressants are rated Moderate, and thyroid hormone replacement therapy is also rated Moderate.

Confirm your exact prescriptions with your own doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This capsule may be of interest to adults looking into lemon balm for stress, depression, or cold sores, since the evidence is rated Possibly Effective for each. People taking CNS depressants or thyroid hormone replacement, and anyone who is pregnant or breastfeeding, should be careful.

Please talk it over with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lemon Balm Extract, straight from the product label.

Brand Earthborn Elements
Net contents 200 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 319605
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lemon Balm Extract by Earthborn Elements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
66
IngredientAmount% DV
Lemon Balm extract1050 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 3 capsules daily or as directed by a physician. Take with at least 8 oz of liquid.

General Statements

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FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lemon Balm Extract by Earthborn Elements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lemon Balm Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lemon Balm Extract by Earthborn Elements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container66 Amounts shown are per serving.

Lemon Balm extract

Interacts with
264 drugs
1050 mg per serving

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold so...

Lemon Balm extract monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lemon Balm Extract by Earthborn Elements Drug Interactions

Want to check YOUR meds against Lemon Balm Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
264Drugs
264 Moderate

Ingredients driving the most interactions

Lemon Balm extract 264

Individual Drug Interactions

The ingredients in Lemon Balm Extract interact with 264 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lemon Balm Extract interact with drugs. Each result below shows which ingredient is responsible. Lemon Balm extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Lemon Balm Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lemon Balm extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.

Likelihood Possible Evidence B
Thyroid Hormone

Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.

Likelihood Possible Evidence D
Lemon Balm extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lemon Balm Extract, from the product label.

Earthborn Elements

See all Earthborn Elements products
Name
Earthborn Elements
Street Address
9450 SW Gemini Dr #49936
City
Beaverton
State
Oregon
ZipCode
97008
Web Address
Earthbornelements.com
Pharmacist Counseling Corner

Lemon Balm Extract by Earthborn Elements: Common Questions

Does Lemon Balm Extract by Earthborn Elements interact with any medications?
Yes. Based on its ingredients, Lemon Balm Extract has a known interaction with 264 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lemon Balm Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lemon balm work for cold sores?
Lemon balm is rated Possibly Effective for herpes labialis (cold sores) in the evidence we hold. That rating is promising but not firm, and the cold sore research we hold includes a 1% lemon balm cream.
Can I take this while pregnant?
Our safety data advises avoiding lemon balm during pregnancy unless your doctor advises otherwise, because there is not enough reliable safety data. Please talk with your own doctor or pharmacist for advice about your situation.
Does this capsule cause drowsiness?
Dizziness and sedation have been reported with oral lemon balm, but they do not appear to occur more often than with placebo. Research also found that alcohol combined with lemon balm did not affect reaction time.
What is lemon balm used for?
The lemon balm research we hold covers stress and depression, both rated Possibly Effective, as well as cold sores. These ratings reflect the current evidence and do not guarantee results.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lemon Balm Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lemon Balm Extract label
Go deeper

The Full Monographs Behind Lemon Balm Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lemon Balm

Interacts with 264 drugs

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...

Read the full Lemon Balm monograph →
Sources

Sources & How We Checked

Lemon Balm Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lemon Balm 12 references
  1. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
  2. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
  3. Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
  4. Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
  5. Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
  6. Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
  7. Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
  8. Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
  9. Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
  11. Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
  12. Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.

See these in context on the Lemon Balm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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