Doxepin (Insomnia)
A homeopathic sublingual spray used to temporarily ease occasional sleeplessness tied to anxiety, stress, or restlessness.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 1 clinical label set within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
📖 Doxepin (Insomnia): Patient Information Guide
A plain-language walkthrough of Doxepin (Insomnia) — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.
🎯What it's used for▾
This product is used to temporarily relieve occasional difficulty sleeping related to:
- Anxiety
- Restlessness
- Stress
- Caffeine sensitivity
Important: These claims are based on traditional homeopathic practice — they are not supported by accepted medical evidence and have not been evaluated by the FDA.
💊How it's taken▾
This product comes as a sublingual spray — meaning you spray it directly under your tongue, where it absorbs quickly. Adults and children 12 and older use two sprays under the tongue at bedtime, and again if nighttime restlessness wakes them up.
- Children under 12: check with a doctor first before using.
- No food restrictions are listed, but follow the product label directions closely.
🤒Side effects — in detail▾
The label does not list specific side effects for this product. However, stop use and seek help if you believe you are having an allergic reaction, or if your symptoms worsen or don't improve within 7 days.
⚠️Warnings & precautions▾
- Short-term use only: If sleep troubles last more than 7 days, get worse, or if new symptoms appear, stop use and talk to a doctor.
- Allergic reactions: Do not use if you've ever reacted to this product or its ingredients.
- Tamper seal: Do not use the product if the tamper-evident seal on the bottle is missing or broken.
- Keep out of reach of children.
- Overdose: If too much is taken, call Poison Control or get emergency help right away.
- Pregnancy and breastfeeding: Ask a doctor before using.
🔀What it interacts with▾
The label does not list specific drug, food, or supplement interactions for this product. If you take other medications or have health conditions, check with your pharmacist or doctor before using.
This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.
📋Before taking it▾
- Do not use if you have ever had an allergic reaction to this product or any of its ingredients.
- If you are pregnant or breastfeeding, consult a doctor before use.
- Children under 12 should only use this product under a doctor's guidance.
🚑If you take too much▾
The label does not describe specific overdose symptoms. If you think someone has taken too much, call a Poison Control Center right away or get emergency medical help immediately — don't wait for symptoms to appear.
📄 Written from Doxepin (Insomnia)’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →
Supplements & herbs that interact with Doxepin (Insomnia)
186 supplements and herbal products have documented interactions with Doxepin (Insomnia) in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 15
- Moderate · 145
- Minor · 26
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Nutrient depletion considerations
Doxepin (Insomnia) has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.
Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.
🩺 Pharmacist Counseling Corner
Quick, plain-English answers to the questions patients ask most about Doxepin (Insomnia) — the kind of thing our pharmacy team would talk through with you at the counter.
What exactly is this product, and is it the same as prescription doxepin? ▾
How do I use it correctly? ▾
How long can I use this product? ▾
Is it safe to use if I'm pregnant or breastfeeding? ▾
What should I do if I accidentally take too much? ▾
How do I know the product is safe to use when I open it? ▾
Is Doxepin (Insomnia) available over the counter? ▾
💬 Answers drafted from Doxepin (Insomnia)’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →
🧰 Keep exploring
📈 How widely Doxepin (Insomnia) is used
A general measure of how commonly Doxepin (Insomnia) is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Doxepin (Insomnia) is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Doxepin (Insomnia) prescribed? Of the 1,596 medications we measure, Doxepin (Insomnia) ranks #233 by Medicaid prescriptions — more than 85% of them.
Utilization by Doxepin (Insomnia) product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
doxepin 10 MG Oral Capsule Most dispensed
Summed across the 16 of 95 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000048
doxepin 25 MG Oral Capsule
Summed across the 14 of 113 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000070
doxepin 50 MG Oral Capsule
Summed across the 14 of 82 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000076
doxepin 100 MG Oral Capsule
Summed across the 13 of 52 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000058
doxepin hydrochloride 50 MG/ML Topical Cream
Summed across the 6 of 6 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000091
doxepin 150 MG Oral Capsule
Summed across the 5 of 15 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000064
doxepin 75 MG Oral Capsule
Summed across the 12 of 45 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000097
doxepin 10 MG/ML Oral Solution
Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1000054
doxepin 3 MG Oral Tablet
Summed across the 8 of 43 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 966787
doxepin 6 MG Oral Tablet
Summed across the 8 of 48 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 966793
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Doxepin (Insomnia), and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 97 of 501 listed Doxepin (Insomnia) NDCs with Medicaid activity.
📈 What people report — real-world data (FDA FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Doxepin (Insomnia) — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Doxepin (Insomnia) in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
🏛️ The road to your pharmacy
How Doxepin (Insomnia) went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
🚨 Recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
Source: openFDA drug enforcement (recall) reports.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 3638 4 dose forms · 10 strengths
-
Dose form (SCDF) Oral Capsule RxCUI 371962No current FDA listing -
Dose form (SCDF) Oral Solution RxCUI 379135No current FDA listingClinical drug / strength (SCD) 10 MG/MLRxCUI 1000054 -
Dose form (SCDF) Oral Tablet RxCUI 375040No current FDA listing -
Dose form (SCDF) Topical Cream RxCUI 377691No current FDA listingClinical drug / strength (SCD) hydrochloride 50 MG/MLRxCUI 1000091
Look up RxCUI 3638 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
📦 Supply & shortage status
Whether Doxepin (Insomnia) is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
🏷️ Sold under these brand names
RxNorm drug class
Doxepin (Insomnia) belongs to the Tricyclic Antidepressant class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
🔬 Where this comes from
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How we combine label and product data
HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 1 FDA-filed SPL label set within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.
For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Liddell Laboratories, Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.
This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.