Lipotropic Factors Ingredients & Drug Interactions
by Solgar
What is this page for?
First and foremost: checking Lipotropic Factors against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lipotropic Factors is a dietary supplement by Solgar with 3 active ingredients. Its ingredients are commonly taken for acetaminophen (tylenol) overdose support, liver health, urinary tract acidification.Based on those ingredients, 102 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol, Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Lipotropic Factors by Solgar
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Lipotropic Factors by Solgar
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Lipotropic Factors contains three active ingredients. L-methionine is an amino acid that may help with neural tube birth defects in pregnancy, though evidence for other uses is insufficient.
Choline is an essential nutrient studied for cognitive and liver health but shows mostly inconclusive evidence. Inositol, a sugar alcohol, appears possibly effective for polycystic ovary syndrome and metabolic syndrome.
The product also contains inactive ingredients — microcrystalline cellulose, vegetable cellulose, silica, vegetable magnesium stearate, vegetable glycerin, and titanium dioxide — which are fillers and binders.
Does it work?
Moderate evidence
Evidence for this product's uses is mixed. Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome.
L-methionine is possibly effective for neural tube birth defects in pregnancy. For the other conditions listed in our data — including Alzheimer's disease, cognitive decline, athletic performance, and allergic rhinitis — evidence is insufficient to make a reliable rating.
Talk with your pharmacist or doctor about whether this product matches your specific goal.
How safe is it?
Well-documented data
L-methionine is well tolerated in food amounts, but high-dose supplements may cause dizziness, drowsiness, headache, and vomiting. Choline is generally well tolerated at normal doses; adverse effects are mainly reported at very high intakes (9 grams or more daily), where it may cause nausea, vomiting, and a fishy body odor.
Inositol is generally well tolerated, with mostly mild digestive side effects like diarrhea, gas, and nausea. L-methionine is rated Likely Safe in pregnancy and lactation; choline is also rated Likely Safe, though prenatal or supplement doses should follow your doctor's guidance.
Safety data for inositol during pregnancy is not fully established — use only under medical supervision if you're pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
If you take antidiabetes drugs (blood sugar medications), inositol in this product may increase the risk of low blood sugar — a Moderate interaction that needs monitoring. Choline may theoretically decrease the effects of atropine, a Minor interaction.
Run your exact medications through the checker on this page before starting.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Lipotropic Factors may be worth considering if you have PCOS, metabolic syndrome, or are planning pregnancy (for the methionine). If you take diabetes medications, blood sugar medications, or atropine, check your exact medications with the tool below before starting.
Talk with your pharmacist about whether this product fits your health goals and current medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lipotropic Factors, straight from the product label.
| Brand | Solgar |
|---|---|
| Barcode (UPC) | 033984015814 |
| Net contents | 100 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2019 |
| DSLD ID | 201366 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lipotropic Factors by Solgar, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| L-Methionine | 1 Gram(s) | -- |
| Choline | 410 mg | 75% |
| Inositol | 1 Gram(s) | -- |
Other ingredients: Microcrystalline Cellulose, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate, Vegetable Glycerin, Titanium Dioxide color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Free of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener and preservatives.
Gluten, wheat & dairy free
Non-GMO
Suitable for vegans
Formula
Solgar’s KOF-K certification #K-1250
Brand IP Statement(s)
2017 Solgar, Inc.
General
SOLGB71580 03C
General Statements
Since 1947
Seals/Symbols
GF Certified Gluten-free
K Parve
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement for adults, take three (3) tablets daily, preferably with a meal or as directed by a healthcare practitioner.
Precautions
If you are pregnant, nursing, taking any medications or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement.
Discontinue use and consult your healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
Do not use if outer bottle seal is missing or damaged.
Storage
Store at room temperature.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lipotropic Factors by Solgar label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lipotropic Factors by Solgar
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container33 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Methionine
No knowninteractions
Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a norma...
L-Methionine monograph & interactionsCholine
Interacts with16 drugs
Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...
Choline monograph & interactionsInositol
Interacts with86 drugs
Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...
Inositol monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate, Vegetable Glycerin, Titanium Dioxide color. These complete the product’s ingredient list but are not active constituents.
Lipotropic Factors by Solgar Drug Interactions
HelloPharmacist Interaction Report
Lipotropic Factors by Solgar contains three active ingredients with documented interactions spanning 101 individual medications.
The most serious interaction involves inositol and antidiabetes drugs (blood sugar medications). Inositol lowers blood glucose levels, so taking it alongside diabetes medications may increase the risk of low blood sugar (hypoglycemia) — a Moderate-severity interaction that needs monitoring.
Read the full breakdown — every affected drug type, severity by severity
Choline has a Minor interaction with atropine, an anticholinergic medication sometimes used for certain conditions. Choline may theoretically reduce atropine's effects in the brain, though this is based on animal research rather than human trials.
L-methionine, the third active ingredient, has no interactions documented in our data. That said, absence of documented interactions isn't a guarantee none exist — it means we hold no monograph data showing problems with other drugs.
Use the medication checker below to verify your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Lipotropic Factors?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Lipotropic Factors interact with 102 drugs. Click any drug to see the details.
2 of the 3 ingredients in Lipotropic Factors interact with drugs. Each result below shows which ingredient is responsible. Inositol Choline
GlucoseIV Glucose
How Glucose interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Glucose interactionGlyburideAlbert Glyburide, Diabeta, Glycron, Glynase, Glynase PresTab, Micronase +1 more
How Glyburide interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Glyburide interactionGlyburide, MetforminGlucovance
How Glyburide, Metformin interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Glyburide, Metformin interactionInhaled InsulinExubera
How Inhaled Insulin interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Inhaled Insulin interactionInsulinNovoRapid Insulin
How Insulin interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin interactionInsulin (bovine)Hypurin Bovine Neutral
How Insulin (bovine) interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin (bovine) interactionInsulin (human)Afrezza, Novolin 70/30, Novolin L, Novolin N, Novolin R
How Insulin (human) interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin (human) interactionInsulin (pork)Hypurin Porcine Neutral, Lente Iletin II, NPH Iletin, NPH Iletin II, Pork Actrapid, Regular Iletin +1 more
How Insulin (pork) interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin (pork) interactionInsulin (rdna)Actrapid, Humalog, Humalog Mix 75/25, Humulin 50/50, Humulin 70/30, Humulin L +8 more
How Insulin (rdna) interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin (rdna) interactionInsulin AspartFiasp
How Insulin Aspart interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Aspart interactionInsulin Aspart, Insulin DegludecRyzodeg 70/30
How Insulin Aspart, Insulin Degludec interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Aspart, Insulin Degludec interactionInsulin DegludecTresiba
How Insulin Degludec interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Degludec interactionInsulin Degludec, LiraglutideXultophy 100/3.6
How Insulin Degludec, Liraglutide interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Degludec, Liraglutide interactionInsulin GlargineBasaglar, Lusduna, Semglee
How Insulin Glargine interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Glargine interactionInsulin Glargine (rdna)Lantus
How Insulin Glargine (rdna) interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Glargine (rdna) interactionInsulin Glargine RecombinantToujeo Solostar
How Insulin Glargine Recombinant interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Glargine Recombinant interactionInsulin Glargine, LixisenatideSoliqua 100/33
How Insulin Glargine, Lixisenatide interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Glargine, Lixisenatide interactionInsulin Glulisine (rdna)Apidra
How Insulin Glulisine (rdna) interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Glulisine (rdna) interactionInsulin Human, Sodium ChlorideMyxredlin
How Insulin Human, Sodium Chloride interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Human, Sodium Chloride interactionInsulin LisproAdmelog, Admelog Solostar
How Insulin Lispro interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Lispro interactionInsulin Lispro RecombinantHumalog Kwikpen
How Insulin Lispro Recombinant interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Lispro Recombinant interactionInsulin Lispro-aabcLyumjev
How Insulin Lispro-aabc interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Lispro-aabc interactionInsulin DetermirLevemir
How Insulin Determir interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Insulin Determir interactionLinagliptinTradjenta
How Linagliptin interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Linagliptin interactionLinagliptin, Metformin HydrochlorideJentadueto XR
How Linagliptin, Metformin Hydrochloride interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Linagliptin, Metformin Hydrochloride interactionLiraglutideVictoza
How Liraglutide interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Liraglutide interactionLiraglutide RecombinantSaxenda
How Liraglutide Recombinant interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Liraglutide Recombinant interactionLixisenatideAdlyxin
How Lixisenatide interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Lixisenatide interactionMetforminGlucophage, Metformin
How Metformin interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Metformin interactionMetformin HydrochlorideRiomet ER
How Metformin Hydrochloride interacts with Lipotropic Factors — through 1 ingredient. Tap an ingredient for the detail:
InositolAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Inositol + Metformin Hydrochloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Lipotropic Factors with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Inositol
Antidiabetes Drugs
Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.
Choline
Atropine
Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.
Brand information
Manufacturer and brand details for Lipotropic Factors, from the product label.
Solgar
See all Solgar products- Name
- Solgar, Inc.
- Street Address
- 500 Willow Tree Road
- City
- Leonia
- State
- NJ
- ZipCode
- 07605
- Phone Number
- 1-877-765-4274
- Web Address
- www.solgar.com
Lipotropic Factors by Solgar: Common Questions
Does Lipotropic Factors by Solgar interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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Does this product work for weight loss or metabolism?
Can this help with Alzheimer's disease or memory?
Is there anything else in this tablet besides the active ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lipotropic Factors is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lipotropic Factors’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Methionine
Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a normal diet, and supplements are generally no...
Read the full Methionine monograph → Herb & supplement monographCholine
Interacts with 16 drugsCholine is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...
Read the full Choline monograph → Herb & supplement monographInositol
Interacts with 86 drugsInositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...
Read the full Inositol monograph →Sources & How We Checked
Lipotropic Factors's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Methionine 12 references
- La Vecchia C, Negri E, Franceschi S, Decarli A. Case-control study on influence of methionine, nitrite, and salt on gastric carcinogenesis in northern Italy. Nutr Cancer 1997;27:65-8. PubMed
- Btaiche IF, Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002;22:188-211.. PubMed
- Cottington EM, LaMantia C, Stabler SP, et al. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol 2002;22:1046-50.. PubMed
- Anon. Should methionine be added to paracetamol formulations? Drug Ther Perspect 1997;10:11-3. DOI
- Smulders, Y. M., Rakic, M., Slaats, E. H., Treskes, M., Sijbrands, E. J., Odekerken, D. A., Stehouwer, C. D., and Silberbusch, J. Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and c
- McAuley, D. F., Hanratty, C. G., McGurk, C., Nugent, A. G., and Johnston, G. D. Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. J.Toxicol.Clin.Toxicol. 1999;37(4):435-440. PubMed
- Hanratty, C. G., McGrath, L. T., McAuley, D. F., Young, I. S., and Johnston, G. D. The effects of oral methionine and homocysteine on endothelial function. Heart 2001;85(3):326-330. PubMed
- Ward, M., McNulty, H., McPartlin, J., Strain, J. J., Weir, D. G., and Scott, J. M. Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study. Int.J.Vitam.Nutr.Res. 2001;71(1):82-86. PubMed
- Yaghmai, R., Kashani, A. H., Geraghty, M. T., Okoh, J., Pomper, M., Tangerman, A., Wagner, C., Stabler, S. P., Allen, R. H., Mudd, S. H., and Braverman, N. Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient
- Talukdar R, Murthy HV, Reddy DN. Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis. Pancreatology 2015;15(2):136-44. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005. Available at: https://doi.org/10.17226 DOI
- Khairan P, Sobue T, Eshak ES, et al. Association of B Vitamins and Methionine Intake with the Risk of Gastric Cancer: The Japan Public Health Center-based Prospective Study. Cancer Prev Res (Phila) 2022;15(2):101-110. PubMed
Choline 14 references
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
- Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
- Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
- Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
- Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
- Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
- Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
- Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
- Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
- Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
- Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
- Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
- Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.
Inositol 14 references
- Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
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