Interactions on record — worth a quick check against your medications. Based on 6 of 8 ingredients. Check your meds →
Dietary supplement

LiverCare Powder Ingredients & Drug Interactions

by Himalaya

LiverCare Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking LiverCare Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

LiverCare Powder is a dietary supplement by Himalaya with 8 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,135 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Arjuna (bark) extract, Caper Bush (root) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against LiverCare Powder by Himalaya

Ask about any prescription or over-the-counter medication and we check it for interactions with LiverCare Powder by Himalaya — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of LiverCare Powder by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label gives one combined amount (374 mg) without saying how much of each component you get.

LiverCare Powder contains 7 ingredients: a proprietary herbal blend (whose components are listed separately), plus Caper Bush root extract, Chicory seed extract, Black Nightshade whole plant extract, Arjuna bark extract, Yarrow aerial parts extract, Cassia occidentalis seed extract, and Tamarisk whole plant extract. The inactive ingredients are partially hydrolyzed Guar Gum and Steviol Glycosides (a sweetener).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: liver performance and detoxification support.
  • We looked for evidence on: Cirrhosis, Nonalcoholic fatty liver disease (NAFLD), hepatic function, liver enzyme levels, liver cell protection.
  • The closest evidence on file: Chicory is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD) (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD).
  • Also on file: Black Nightshade is rated "Insufficient Reliable Evidence To Rate" for Cirrhosis.

The evidence for effectiveness isn't established in the data we hold. Caper Bush, Chicory, Arjuna, and Yarrow all show insufficient reliable evidence to rate for the conditions they're traditionally used for — including liver health, blood sugar control, cholesterol, blood pressure, and wound healing.

Black Nightshade similarly has insufficient evidence for acne, cirrhosis, and shingles.

The evidence, ingredient by ingredient Black Psyllium Capers Chicory Black Nightshade Terminalia Yarrow

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in food amounts, but the safety of concentrated supplements varies. Caper Bush and Chicory seem generally well tolerated orally, though Chicory can cause gas and may trigger allergies in sensitive people.

Yarrow and Arjuna have limited long-term human safety data. Black Nightshade carries real toxicity risk from unripe berries and green parts — only fully ripe fruit or properly cooked leaves are traditionally considered safer.

Pregnancy and breastfeeding data are limited or advise caution. Chicory is possibly unsafe in pregnancy (may stimulate the uterus), and Black Nightshade, Arjuna, and Yarrow are advised against in pregnancy due to insufficient data or risk of uterine effects.

Black Nightshade is likely unsafe while breastfeeding. Talk with your doctor or pharmacist about use during pregnancy or breastfeeding.

Side effects, ingredient by ingredient Black Psyllium Capers Chicory Black Nightshade Terminalia Yarrow

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Chicory, Black Psyllium, Yarrow, Capers, Terminalia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,136 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take anticoagulant or antiplatelet drugs (blood thinners or aspirin-like medications) — Arjuna may increase bleeding risk. Also check any medications that rely on liver enzymes to break down (CYP2D6, CYP2C9, or CYP3A4 substrates), antidiabetes drugs, lithium, or the stomach drugs omeprazole and chlorzoxazone.

Altogether, these interactions span 935 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

LiverCare Powder is a multi-ingredient herbal blend with documented interactions — especially with blood thinners, liver-processing enzymes, diabetes drugs, and lithium. The evidence for its effectiveness isn't established in our data.

If you take any prescription medications, particularly anticoagulants, diabetes drugs, or mood stabilizers, check your specific list with your doctor or pharmacist before starting this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LiverCare Powder, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069600040
Net contents 56 Packet(s); 7.9 Oz(s); 224 Gram(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80698
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LiverCare Powder by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Gram(s)
Maximum serving Sizes:
4 Gram(s)
Servings per container
56
UPC/BARCODE
605069600040
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Dietary Fiber4 Gram(s)14%
Proprietary Herbal Blend374 mg--
Caper Bush (root) extract0 NP--
Chicory (seed) extract0 NP--
Black Nightshade (whole plant) extract0 NP--
Arjuna (bark) extract0 NP--
Yarrow (aerial parts) extract0 NP--
Cassia occidentalis (seed) extract0 NP--
Tamarisk (whole plant) extract0 NP--

Other ingredients: partially hydrolyzed Guar Gum, Steviol Glycosides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Boosts liver performance & detox Protects liver cells & enzymes

The blend of herbs in LiverCare protects from free-radical damage, promotes cellular lifespan and supports optimal detox performance by empowering the liver's capacity.

LiverCare protects normal liver enzyme levels as well as bilirubin, both of which are key indicators of liver performance.

cGMP

Happiness through wellness

Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy.

Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties.

Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment.

Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs.

Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities.

Family owned for more than 85 years

Since 1930

Mix one daily

8x7 count - 0.14 oz. (4g) packets

Mfg. Lic. No. AUS-83

Product of India

Brand IP Statement(s)

Ayurveda's wisdom helped craft the holism of LiverCare, which works in multiple capacities to free the body of toxins and waste.

Formula

Featured Herbs On Front: Chicory (leaves), Caper bush (leaves & fruit) & Yarrow (leaves)

Formulation

Gluten free

Vegan friendly

Wheat Corn Soy Dairy

No ingredients of animal origin

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Mix 1 packet daily with water, protein drink, smoothie or other hot or cold liquid.

Precautions

Caution: As with any supplement, consult a healthcare practitioner before use if you are pregnant, nursing, taking medication, have a medical condition or are planning any medical procedure.

Discontinue use and consult a healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

LiverCare Powder by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

LiverCare Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in LiverCare Powder by Himalaya

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Gram(s) Dosage formPowder Servings per container56 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
4 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Proprietary Herbal Blend

374 mg per serving

Other (inactive) ingredients: Partially hydrolyzed Guar Gum, Steviol Glycosides. These complete the product’s ingredient list but are not active constituents.

Interaction report

LiverCare Powder by Himalaya Drug Interactions

Want to check YOUR meds against LiverCare Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,135Drugs
934 Moderate 1,201 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Arjuna (bark) extract 933
Caper Bush (root) extract 86
Chicory (seed) extract 86
Yarrow (aerial parts) extract 1

Individual Drug Interactions

The ingredients in LiverCare Powder interact with 2,135 drugs. Click any drug to see the details.

5 of the 8 ingredients in LiverCare Powder interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Arjuna (bark) extract Caper Bush (root) extract Chicory (seed) extract Yarrow (aerial parts) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in LiverCare Powder with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Arjuna (bark) extract7 drug types · 933 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.

Likelihood Possible Evidence D
Chlorzoxazone (Parafon Forte, Paraflex)

Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.

Likelihood Possible Evidence D
Omeprazole (Prilosec)

Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.

Likelihood Possible Evidence D
Arjuna (bark) extract full monograph & interactions

Caper Bush (root) extract1 drug type · 86 drugs

Antidiabetes Drugs

Some preliminary clinical research shows that taking caper fruit extract 1200 mg daily for 2 months can lower fasting blood glucose and glycated hemoglobin (HbA1c) in patients with type 2 diabetes who are already taking antidiabetes drugs. However, other research does not support this effect. Until more is known, monitor blood glucose levels closely. Medication dose adjustments may be necessary.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Caper Bush (root) extract full monograph & interactions

Chicory (seed) extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, chicory might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research shows that chicory extracts have antidiabetic effects.

Likelihood Possible Evidence D
Chicory (seed) extract full monograph & interactions

Yarrow (aerial parts) extract1 drug type · 1 drug

Lithium

Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yarrow (aerial parts) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for LiverCare Powder, from the product label.

Himalaya

See all Himalaya products
Name
The Himalaya Drug Company
City
Makali
State
Bangalore
ZipCode
562 162
Pharmacist Counseling Corner

LiverCare Powder by Himalaya: Common Questions

Does LiverCare Powder by Himalaya interact with any medications?
Yes. Based on its ingredients, LiverCare Powder has a known interaction with 2,135 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LiverCare Powder contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is LiverCare Powder safe during pregnancy or breastfeeding?
The data advises caution or avoidance. Chicory is possibly unsafe in pregnancy, and Black Nightshade, Arjuna, and Yarrow should be avoided in pregnancy. Black Nightshade should also be avoided while breastfeeding. Talk with your doctor or pharmacist for personalized advice.
Does this product actually work for liver health?
The evidence isn't established in the data we hold. The main ingredients — Caper Bush, Chicory, Black Nightshade, Arjuna, and Yarrow — all show insufficient reliable evidence to rate for their traditional uses.
What are the most common side effects?
Chicory may cause gas, bloating, belching, and abdominal pain. Yarrow can cause dermatitis if applied to skin. Most other ingredients show few or no reported adverse effects in clinical research, though long-term safety data are limited.
Can I take this with my diabetes medication?
Both Caper Bush and Chicory may lower blood sugar, so there's a theoretical risk of low blood sugar (hypoglycemia) if you're already on diabetes drugs. Monitor your blood glucose closely and check with your doctor or pharmacist before adding this product.
What is Black Nightshade in this product, and is it safe?
Black Nightshade is the whole plant (not just the fruit) and carries real toxicity risk from unripe berries and green parts — only fully ripe fruit or properly cooked leaves are traditionally considered safer. The product hasn't been assessed for long-term safety, and it's advised against in pregnancy and breastfeeding.
Why are two ingredients listed as 'not checked'?
Cassia occidentalis and Tamarisk are included, but we hold no interaction data for them — they weren't evaluated for this page. That doesn't mean they're safe; it means we don't have the information. Mention them to your pharmacist if you have concerns.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LiverCare Powder label
Go deeper

The Full Monographs Behind LiverCare Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Capers

Interacts with 86 drugs

Capers are the edible pickled flower buds of the Capparis spinosa shrub, used widely as food and in traditional medicine. They contain antioxidant plant compounds, but high-quality human stu...

Read the full Capers monograph → Herb & supplement monograph

Chicory

Interacts with 86 drugs

Chicory is best known as a caffeine-free coffee substitute and as a source of inulin, a soluble prebiotic fiber that may support digestion and regularity. Strong human evidence for most othe...

Read the full Chicory monograph → Herb & supplement monograph

Black Nightshade

Black nightshade is a wild plant whose cooked ripe berries and leaves are eaten as food in some cultures, but unripe berries and green parts can be poisonous. Human evidence for any health b...

Read the full Black Nightshade monograph → Herb & supplement monograph

Terminalia

Interacts with 933 drugs

Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes. Some small studies suggest possible ben...

Read the full Terminalia monograph → Herb & supplement monograph

Yarrow

Interacts with 1 drug

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...

Read the full Yarrow monograph →
Sources

Sources & How We Checked

LiverCare Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 52 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Capers 3 references
  1. Angelini G, Vena GA, Filotico R, et al. Allergic contact dermatitis from Capparis spinosa L. applied as wet compresses. Contact Dermatitis 1991;24:382-3.
  2. Huseini HF, Hasani-Rnjbar S, Nayebi N, et al. Capparis spinosa L. (Caper) fruit extract in treatment of type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Complement Ther Med. 2013;21(5):447-52. PubMed
  3. Vahid H, Bonakdaran S, Khorasani ZM, et al. Effect of Capparis spinosa extract on metabolic parameters in patients with type-2 diabetes: A randomized controlled trial. Endocr Metab Immune Disord Drug Targets. 2019;19(1):100-107. PubMed

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Chicory 13 references
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  10. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed
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  12. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  13. Devi Kt R, Sivalingam N. Cichorium intybus attenuates Streptozotocin-induced pancreatic ß-cell damage by inhibiting NF-?B activation and oxidative stress. J Appl Biomed 2020;18(2-3):70-9. PubMed

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Black Nightshade 1 reference
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See these in context on the Black Nightshade monograph →

Terminalia 9 references
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  6. Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
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  8. Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
  9. Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed

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Yarrow 8 references
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  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
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  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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