Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Gotu Kola Ingredients & Drug Interactions

by Himalaya

Gotu Kola label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Gotu Kola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Gotu Kola is a dietary supplement by Himalaya with 2 active ingredients. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 579 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Gotu Kola standardized extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Gotu Kola by Himalaya

Ask about any prescription or over-the-counter medication and we check it for interactions with Gotu Kola by Himalaya — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Gotu Kola by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Himalaya Gotu Kola is a 2-ingredient product containing organic gotu kola standardized extract and organic gotu kola powder. Both are forms of the same plant, traditionally used in herbal medicine.

There are no inactive ingredients (fillers or binders) listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gotu Kola's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: memory enhancer.
  • We looked for evidence on: Cognitive function, Alzheimer disease, Mental clarity, Age-related cognitive decline.
  • The closest evidence on file: Gotu Kola is rated "Possibly Ineffective" for Cognitive function (Natural Medicines).
  • Also on file: Gotu Kola is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease.

The evidence for gotu kola is mixed. It's possibly effective for venous insufficiency (poor circulation in the legs) and burns.

However, it's rated possibly ineffective for radiation dermatitis and cognitive function. For Alzheimer's disease and generalized anxiety disorder, there isn't enough reliable evidence to rate how well it works.

The evidence, ingredient by ingredient Gotu Kola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gotu kola is generally well tolerated over the short term, though quality evidence is limited. The most common side effects when taken orally are stomach irritation and nausea.

Liver toxicity is rare but has been reported in case studies; one clinical trial monitoring liver function found no changes at 120 mg daily for 6 months, but doses and product quality varied in the cases where problems occurred. There isn't enough safety data for pregnancy—it's traditionally been avoided during pregnancy.

Safety during breastfeeding is unknown, so it's best avoided if you're nursing. Talk with your doctor or pharmacist about whether it's right for you if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Gotu Kola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gotu Kola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 580 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Gotu Kola, check with your doctor or pharmacist if you take CNS depressants (sedatives, sleep aids, anxiety or pain medications with sedative properties)—gotu kola may increase drowsiness. Also double-check any medications known to affect liver function.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Gotu Kola by Himalaya may be worth considering if you're looking into support for venous insufficiency or minor burns and want a plant-based option. If you take any sedating medications or drugs that affect your liver, check with your doctor or pharmacist before starting.

Pregnant or breastfeeding? That's a conversation for your healthcare provider.

Run your medication list through the tool on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 29, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gotu Kola, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069426015
Net contents 60 Caplet(s)
Market status On market
Date entered into DSLD Dec 29, 2014
DSLD ID 40323
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gotu Kola by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
Servings per container
60
UPC/BARCODE
605069426015
IngredientAmount% DV
organic Gotu Kola standardized extract250 mg--
organic Gotu Kola powder400 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

- Contains asiaticosides

Brand IP Statement(s)

Our Science. Your Life.(TM)

General Statements

- Over 1,200 clinical studies on Himalaya products - Nearly 200 scientists, herbalists and doctors on R&D staff - Seed-to-shelf company - GMP Facility - Family owned since 1930

PURE HERBS

MEMORY ENHANCER

HOW CAN GOTU KOLA HELP YOU? - Supports memory and attention through the production of collagen, the key to healthy connective tissues surrounding the veins - Supports collagen production for healthy brain capillaries, helping improve mental alertness

Mfg. Lic. No. AUS-83

Product of INDIA

Chromatographic Fingerprinting: The most rigorous testing for herbal potency.

Seals/Symbols

USDA ORGANIC

{image} H

India Organic

{recycle}

Gotu Kola {graph}

FDA Statement of Identity

HERBAL SUPPLEMENT

Formulation

Additive and Gluten Free

Certified Organic by Control Union Certifications Control Union 806546

Suggested/Recommended/Usage/Directions

Directions: Take 1 caplet per day before food.

General

HUS-5018936

FDA Disclaimer Statement

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.

Precautions

Caution: Keep out of direct light and out of the reach of children.

Storage

Caution: Keep out of direct light and out of the reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Gotu Kola by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Gotu Kola label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Gotu Kola by Himalaya

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Gotu Kola standardized extract

Interacts with
579 drugs
250 mg per serving Form: Triterpenoids

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Organic Gotu Kola standardized extract monograph & interactions

Organic Gotu Kola powder

Interacts with
579 drugs
400 mg per serving Form: Triterpenoids

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Organic Gotu Kola powder monograph & interactions
Interaction report

Gotu Kola by Himalaya Drug Interactions

Want to check YOUR meds against Gotu Kola?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
579Drugs
579 Moderate

Ingredients driving the most interactions

organic Gotu Kola standardized extract 579

Individual Drug Interactions

The ingredients in Gotu Kola interact with 579 drugs. Click any drug to see the details.

1 of the 2 ingredients in Gotu Kola interact with drugs. Each result below shows which ingredient is responsible. organic Gotu Kola standardized extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Gotu Kola with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Gotu Kola standardized extract2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
organic Gotu Kola standardized extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Gotu Kola, from the product label.

Himalaya

See all Himalaya products
Name
The Himalaya Drug Company
City
Makali
State
Bangalore
ZipCode
562 123
Pharmacist Counseling Corner

Gotu Kola by Himalaya: Common Questions

Does Gotu Kola by Himalaya interact with any medications?
Yes. Based on its ingredients, Gotu Kola has a known interaction with 579 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gotu Kola contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
There isn't enough safety data to be sure. Gotu kola has traditionally been avoided during pregnancy. Talk with your doctor or pharmacist about what's right for your situation.
Is it safe while breastfeeding?
Safety during breastfeeding isn't established in the data we hold. It's best to avoid it and discuss with your doctor or pharmacist before using.
What are the side effects?
Most common side effects when taken by mouth are stomach irritation and nausea. Liver toxicity is rare but has been reported; one clinical trial at 120 mg daily for 6 months showed no liver changes, though this was in a monitored setting.
Does gotu kola actually work for anxiety?
There isn't enough reliable evidence to rate how well it works for general anxiety. You'd want to talk with your doctor about proven options for anxiety management.
What is gotu kola used for?
Gotu kola is possibly effective for venous insufficiency (circulation problems in the legs) and burns. Evidence is lacking or points to ineffectiveness for other uses like cognitive function or radiation skin damage.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gotu Kola is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gotu Kola label
Go deeper

The Full Monographs Behind Gotu Kola’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph →
Sources

Sources & How We Checked

Gotu Kola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team