VigorCare For Men Ingredients & Drug Interactions
by Himalaya
What is this page for?
First and foremost: checking VigorCare For Men against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
VigorCare For Men is a dietary supplement by Himalaya with 10 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 521 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saffron, Tribulus extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against VigorCare For Men by Himalaya
Ask about any prescription or over-the-counter medication and we check it for interactions with VigorCare For Men by Himalaya — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of VigorCare For Men by Himalaya
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
VigorCare For Men has 10 ingredients, including a proprietary herbal blend. The active ingredients are tribulus extract and tribulus (listed separately), saffron, saffron extract, almond, almond extract, blepharis, hygrophilia, hygrophilia extract, and blepharis extract.
The only inactive ingredient listed is plant-based cellulose.
Does it work?
Moderate evidence
Tribulus is possibly effective for sexual dysfunction. The evidence for it improving athletic performance is possibly ineffective, and there isn't enough reliable evidence to rate whether it helps benign prostatic hyperplasia (an enlarged prostate).
Saffron is possibly effective for chemotherapy-induced peripheral neuropathy (nerve damage from cancer treatment) and Alzheimer disease. Almond hasn't been studied enough in supplement form to establish whether it works for aging skin, ADHD, cancer, heart disease, or constipation.
How safe is it?
Well-documented data
Tribulus is generally well tolerated short-term in healthy adults, but quality and long-term safety data are limited. Rare serious side effects include liver and kidney injury, seizures, and painful erection.
Gastrointestinal side effects like nausea, vomiting, diarrhea, and cramping can occur, though one study found rates similar to placebo. Saffron is generally well tolerated but can cause gastrointestinal complaints, nausea, sedation, and vomiting.
Serious allergic reactions, including anaphylaxis, are rare but reported. At higher doses, saffron has caused anxiety and low-level mood elevation in some trial participants.
Almonds are safe as food for most people if you're not allergic, but they're a major allergen. Do not use tribulus during pregnancy or while breastfeeding.
Saffron in medicinal amounts should be avoided during pregnancy due to potential uterine stimulation, and there isn't enough safety data for supplement amounts while breastfeeding.
Meds to double-check
Moderate interaction found
Check your medications against this product if you take blood pressure pills (antihypertensive drugs), blood sugar medications (antidiabetes drugs), sedating medications (CNS depressants), lithium, or heavy caffeine—these are Moderate interactions. If you take any prescription medications at all, run them through the checker on this page.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
VigorCare For Men may help with sexual dysfunction, but you'll need to check your medications first—especially if you take blood pressure pills, blood sugar medications, sedatives, lithium, or heavy caffeine. Talk with your pharmacist before starting if you're pregnant, breastfeeding, or have a tree-nut allergy.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about VigorCare For Men, straight from the product label.
| Brand | Himalaya |
|---|---|
| Barcode (UPC) | 605069015028 |
| Net contents | 60 Vegetarian Capsules |
| Market status | On market |
| Date entered into DSLD | Nov 20, 2017 |
| DSLD ID | 80235 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult Male (18-50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for VigorCare For Men by Himalaya, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Herbal Blend | 600 mg | -- |
| Tribulus extract | 0 NP | -- |
| Tribulus | 0 NP | -- |
| Saffron | 0 NP | -- |
| Saffron extract | 0 NP | -- |
| Almond | 0 NP | -- |
| Almond extract | 0 NP | -- |
| Blepharis | 0 NP | -- |
| Hygrophilia | 0 NP | -- |
| Hygrophilia extract | 0 NP | -- |
| Blepharis extract | 0 NP | -- |
Other ingredients: Plant Based Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Ayurveda teaches that intimacy is a sacred act and describes it as a critical factor for a healthy, emotionally satisfying relationship. The ancient text suggest the sacredness with which a society approaches intimacy mirrors the health of the society at large.
With this in mind, Ayurveda identified important plants that can evoke a healthy, satisfying desire that honors the role of intimacy.
cGMP
Happiness through wellness
Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy.
Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties.
Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment.
Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs.
Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities.
Family owned for more than 85 years
Since 1930
Boosts libido & performance Enhances desire & energy
Happiness through wellness
1 month supply
Mfg. Lic. No. AUS-83
Product of India
Questions? Please call 1-800-869-4640 or visit www.himalayausa.com
Formula
VigorCare for men combines those herbs to promote sexual performance and energetic intimacy.
Featured herbs on front: Almonds (seeds), Blepharis (aerial parts) & Saffron (flower)
Contains: Almond
Formulation
Gluten free
Vegan friendly
Wheat, corn, soy, dairy
No ingredients of animal origin
Non-GMO Gluten free
General
HUS-5033347
Seals/Symbols
Non GMO Project Verified nongmoproject.org
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Recommended Use: Adults take 2 capsules daily, one hour before bedtime.
Precautions
Contains: Almond
Caution: As with any supplement, consult a healthcare practitioner before use if you are taking medication, have a medical condition or are planning any medical procedure.
Discontinue use and consult a healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
VigorCare For Men by Himalaya label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in VigorCare For Men by Himalaya
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Herbal Blend
- › Tribulus extract
- › Tribulus
- › Saffron
- › Saffron extract
- › Almond
- › Almond extract
- › Blepharis
- › Hygrophilia
- › Hygrophilia extract
- › Blepharis extract
Other (inactive) ingredients: Plant Based Cellulose. These complete the product’s ingredient list but are not active constituents.
VigorCare For Men by Himalaya Drug Interactions
HelloPharmacist Interaction Report
VigorCare For Men by Himalaya contains ingredients that interact with several medication types.
The most serious concern is tribulus, which can increase blood pressure-lowering effects with blood pressure medications (antihypertensive drugs), raising the risk of excessively low blood pressure (hypotension).
Read the full breakdown — every affected drug type, severity by severity
Saffron in this product interacts with sedating medications (CNS depressants) and can add to their drowsiness. It also pairs with blood pressure and blood sugar medications the same way tribulus does—potentially increasing the lowering effect on both.
Saffron may also slow how your body processes caffeine, which could increase caffeine's effects.
Tribulus interacts with lithium by potentially raising its levels in your blood, which might require a dose adjustment. Almonds and almond extract in this formula have no documented interactions.
We could not check blepharis, hygrophilia, and their extracts—interaction data isn't on file for them.
Altogether, these interactions span 518 individual medications. Before you start VigorCare For Men, use the medication checker on this page to look up your exact prescriptions.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against VigorCare For Men?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in VigorCare For Men interact with 521 drugs. Click any drug to see the details.
2 of the 10 ingredients in VigorCare For Men interact with drugs. Each result below shows which ingredient is responsible. Saffron Tribulus extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with VigorCare For Men — through 2 ingredients. Tap an ingredient for the detail:
Saffron ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Saffron Extract + Acarbose interactionTribulusAntidiabetes Drugs Moderate
Interaction Summary
Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Tribulus + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with VigorCare For Men — through 2 ingredients. Tap an ingredient for the detail:
TribulusAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Read the full Tribulus + Acebutolol interactionSaffron ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Read the full Saffron Extract + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acepromazine interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffron Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Oxycodone interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Pentazocine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with VigorCare For Men — through 1 ingredient. Tap an ingredient for the detail:
Saffron ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffron Extract + Acetaminophen, Propoxyphene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in VigorCare For Men with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Saffron
Antidiabetes Drugs
Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.
Antihypertensive Drugs
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.
Caffeine
Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.
Cns Depressants
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.
Tribulus extract
Antidiabetes Drugs
Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.
Antihypertensive Drugs
Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.
Lithium
Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for VigorCare For Men, from the product label.
Himalaya
See all Himalaya products- Name
- The Himalaya Drug Company
- City
- Makali
- State
- Bangalore
- ZipCode
- 562 162
VigorCare For Men by Himalaya: Common Questions
Does VigorCare For Men by Himalaya interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does tribulus actually improve sexual function?
Can I take this if I'm on blood pressure medication?
What side effects might I notice?
Is this safe during pregnancy?
Can I take this if I'm allergic to tree nuts?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if VigorCare For Men is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind VigorCare For Men’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Tribulus
Interacts with 259 drugsTribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...
Read the full Tribulus monograph → Herb & supplement monographSaffron
Interacts with 521 drugsSaffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research uses small trials, so results are not defi...
Read the full Saffron monograph → Herb & supplement monographSweet Almond
Sweet almonds are a nutritious tree nut rich in healthy fats, fiber, protein, vitamin E, and minerals, and they are generally safe and healthy to eat as part of a balanced diet. Almond oil i...
Read the full Sweet Almond monograph →Sources & How We Checked
VigorCare For Men's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Tribulus 10 references
- Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
- Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
- Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
- Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
- Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
- Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
- Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
- Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
- Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
- Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.
Saffron 22 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Feo F, Martinez J, Martinez A, et al. Occupational allergy in saffron workers. Allergy 1997;52:633-41. PubMed
- Wuthrich B, Schmid-Grendelmeyer P, Lundberg M. Anaphylaxis to saffron. Allergy 1997;52:476-7. PubMed
- Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. Phytother Res 2005;19:148-51.
- Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasth
- Fatehi, M., Rashidabady, T., and Fatehi-Hassanabad, Z. Effects of Crocus sativus petals' extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. J Ethnopharmacol. 2003; PubMed
- Modaghegh, M. H., Shahabian, M., Esmaeili, H. A., Rajbai, O., and Hosseinzadeh, H. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. Phytomedicine. 2008;15(12):1032-1037. PubMed
- Imenshahidi, M., Hosseinzadeh, H., and Javadpour, Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. Phytother.Res 12-9-2009;
- Zhang, Y., Shoyama, Y., Sugiura, M., and Saito, H. Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performances in mice. Biol.Pharm Bull. 1994;17(2):217-221. PubMed
- Wuthrich, B., Schmid-Grendelmeyer, P., and Lundberg, M. Anaphylaxis to saffron. Allergy 1997;52(4):476-477. PubMed
- Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SSh, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi A. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and plac
- Kashani L, Eslatmanesh S, Saedi N, Niroomand N, Ebrahimi M, Hosseinian M, Foroughifar T, Salimi S, Akhondzadeh S. Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Ph PubMed
- Kianbakht S, Ghazavi A. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Phytother Res. 2011 Dec;25(12):1801-5. PubMed
- Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. J C
- Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. Int J Impo PubMed
- Talaei A, Hassanpour Moghadam M, Sajadi Tabassi SA, Mohajeri SA. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: a randomized, double-blind, placebo-controlled, pilot clinical trial. J Affect Disord. 2 PubMed
- Azimi P, Ghiasvand R Feizi A, Hariri M, Abbasi B. Effects of cinnamon, cardamom, saffron, and ginger consumption on markers of glycemic control, lipid profile, oxidative stress, and inflammation in type 2 diabetes. Rev Diabet Stud. 2014 Fall-Winter;11(3-4
- Begas E, Bounitsi M, Kilindris T, et al. Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers. Food Chem Toxicol. 2019;130:32-43. PubMed
- Moravej Aleali A, Amani R, Shahbazian H, Namjooyan F, Latifi SM, Cheraghian B. The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabet
- Abbaszadeh-Mashkani S, Hoque SS, Banafshe HR, Ghaderi A. The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment. Phytother Res. 2021; PubMed
Sweet Almond 4 references
- Motaharifard MS, Effatpanah M, Karimi M, et al. Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial. Complement Ther Clin Pract. 2019;36:170-175. PubMed
- Simon D, Nobbe S, Nägeli M, et al. Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Dermatol Ther. 2018;31(6):e12692. PubMed
- Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
- Salama M, Tebben PJ, Al Nofal A. An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk. J Pediatr Endocrinol Metab 2024;37(4):375-379. PubMed
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