Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Organic Tribulus Ingredients & Drug Interactions

by Himalaya

Organic Tribulus label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Tribulus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Tribulus is a dietary supplement by Himalaya with 2 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Tribulus powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Tribulus by Himalaya

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Tribulus by Himalaya — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Tribulus by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Himalaya's Organic Tribulus contains 2 active ingredients: organic tribulus powder and organic tribulus extract—both from the same plant, so you're getting tribulus in two forms. The product has no other listed inactive ingredients, so what you're taking is tribulus, period.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: genitourinary function, prostate health, libido and energy.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Erectile dysfunction (ED), Male infertility, Premature ejaculation, Sexual dysfunction, Female sexual dysfunction — and 1 related terms.
  • The strongest evidence on file: Tribulus is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Erectile dysfunction (ED), Premature ejaculation, Male infertility.

Tribulus is possibly effective for sexual dysfunction based on the evidence we hold. For athletic performance, the data suggests it's possibly ineffective.

For benign prostatic hyperplasia (enlarged prostate), there isn't enough reliable evidence to know whether it works.

The evidence, ingredient by ingredient Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term, tribulus is generally well tolerated in healthy adults, but long-term safety data are limited and quality varies between products. Avoid it during pregnancy—it may affect hormones and safety isn't established.

Also avoid it while breastfeeding due to lack of reliable safety information. Rare serious side effects have been reported: liver and kidney injury, seizures, and a painful erection with impaired sexual function.

More common are stomach upset—abdominal pain, cramping, nausea, vomiting, diarrhea, or constipation—though one study found these occurred at similar rates in people taking tribulus and those on placebo. One case report described someone who drank 2 liters of tribulus water daily for two days and developed weakness, seizures, liver inflammation, and acute kidney injury; they improved after the supplement was stopped and they had dialysis.

Side effects, ingredient by ingredient Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tribulus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on blood pressure medications, diabetes medications, or lithium. All three have moderate-severity interactions with tribulus.

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking at tribulus for sexual function and don't take blood pressure medications, diabetes medications, or lithium, this is worth discussing with your doctor or pharmacist. If you do take any of those three medication types—or if you're pregnant or breastfeeding—check with your own healthcare provider before starting.

Long-term safety data are sparse, so this is a short-term use supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Tribulus, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069407014
Net contents 60 Caplet(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 282992
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Tribulus by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
Servings per container
60
UPC/BARCODE
605069407014
IngredientAmount% DV
organic Tribulus powder438 mg--
organic Tribulus extract250 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Ayurveda made Tribulus famous as a reproductive and urinary tonic but also says it is a full-body, restorative adaptogen. The ancient texts calls Tribulus a rasayana, a select categorization of plants that bestow longevity and vitality.

Featured Herb On Front: Tribulus (aerial parts)

General Statements

This ancient explanation shines light on its diverse actions observed in research. Tribulus promotes genitourinary function and supports prostate health, libido and physical energy.

cGMP

Our cartons are made from 100% recycled fibers, including 40% post-consumer material. Our glass bottles contain at least 48% recycled content.

Happiness through wellness Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy. Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties. Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment. Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs. Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities. Family owned for over 90 years

2 month supply

Mfg. Lic. No. AUS-83

Our cartons are made from 100% recycled fibers, including 40% post-consumer material. Our glass bottles contain at least 48% recycled content.

HUS-5050106

Formulation

Gluten free

Vegan friendly

Wheat Corn Soy Dairy

No ingredients of animal origin

Supports normal urine flow Promotes normal bladder & urinary functions

Non-GMO

Certified USDA Organic

Product of India

Certified Organic by Control Union Certifications Control Union 835047

Brand IP Statement(s)

Himalaya Since 1930

Seals/Symbols

Non GMO Project Verified Nongmoproject.org

USDA Organic

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Adults take 1 caplet per day before food.

Precautions

Caution: As with any supplement, consult a healthcare practitioner before use if you are pregnant, nursing, taking medication, have a medical condition or are planning any medical procedure.

Discontinue use and consult a healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Tribulus by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Tribulus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Tribulus by Himalaya

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Tribulus powder

Interacts with
259 drugs
438 mg per serving Form: Saponins

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Organic Tribulus powder monograph & interactions

Organic Tribulus extract

Interacts with
259 drugs
250 mg per serving Form: Saponins

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Organic Tribulus extract monograph & interactions
Interaction report

Organic Tribulus by Himalaya Drug Interactions

Want to check YOUR meds against Organic Tribulus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
259 Moderate

Ingredients driving the most interactions

organic Tribulus powder 259

Individual Drug Interactions

The ingredients in Organic Tribulus interact with 259 drugs. Click any drug to see the details.

1 of the 2 ingredients in Organic Tribulus interact with drugs. Each result below shows which ingredient is responsible. organic Tribulus powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Tribulus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Tribulus powder3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
organic Tribulus powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Tribulus, from the product label.

Himalaya

See all Himalaya products
Name
Himalaya Wellness USA Ltd.
Street Address
1101 Gillingham Lane
City
Sugar Land
State
Texas
ZipCode
77478
Phone Number
1-800-869-4640
Web Address
www.himalayausa.com
Pharmacist Counseling Corner

Organic Tribulus by Himalaya: Common Questions

Does Organic Tribulus by Himalaya interact with any medications?
Yes. Based on its ingredients, Organic Tribulus has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Tribulus contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does tribulus actually help with sexual function?
The evidence suggests it's possibly effective for sexual dysfunction, meaning there's some support but it's not definitive. Results vary between people, and better research would help us understand it more clearly.
What if I'm on a blood pressure medication—should I avoid this?
Tribulus can lower blood pressure on its own, so combining it with a blood pressure medication could push your pressure too low. Talk it over with your own doctor or pharmacist before adding it—they know your blood pressure numbers and medications and can advise whether it's right for you.
Can I take this if I have diabetes and use medication?
Tribulus may lower blood sugar, so taking it with diabetes medications raises the risk of low blood sugar (hypoglycemia). Check with your own doctor or pharmacist first—they can tell you whether it's safe for your situation and whether your dose needs watching.
Can I use tribulus if I'm pregnant?
No—the safety data advise against it because tribulus may affect hormones and safety in pregnancy isn't established. Talk to your doctor or pharmacist if you're pregnant or planning to become pregnant.
Is tribulus safe long-term?
Short-term use seems well tolerated in healthy adults, but quality and long-term safety data are limited. If you're thinking of taking it regularly, discuss that with your doctor or pharmacist.
What are the stomach side effects I might feel?
Tribulus can cause abdominal pain, cramping, nausea, vomiting, diarrhea, or constipation. However, one study found that people taking tribulus reported these complaints at similar rates to those on placebo, so they may not be directly caused by the supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Tribulus is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Tribulus label
Go deeper

The Full Monographs Behind Organic Tribulus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph →
Sources

Sources & How We Checked

Organic Tribulus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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