Longevitrol Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Longevitrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Longevitrol is a dietary supplement by Earth's Bounty with 1 active ingredient. Its ingredients are commonly taken for athletic performance and strength, energy and fatigue, joint health and arthritis.Based on those ingredients, 52 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Velvet Antler Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Longevitrol by Earth's Bounty
Ask about any prescription or over-the-counter medication and we check it for interactions with Longevitrol by Earth's Bounty — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Longevitrol by Earth's Bounty
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 1 active ingredient.
Only Minor-severity interactions are documented for these ingredients.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Deer Velvet.
- The most serious interaction on file is rated Minor.
- For scale: 52 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety data exists for these ingredients, but with some important gaps.
Why this rating?
- We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Only minor medication interactions are documented, and some safety-information gaps remain.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Longevitrol, straight from the product label.
| Brand | Earth's Bounty |
|---|---|
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 334189 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Longevitrol by Earth's Bounty, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Velvet Antler Extract | 0 NP | -- |
Other ingredients: Water, Glycerin, Ascorbic Acid, Trace Mineral Complex, Maca Root Extract, Green Tea Leaf Extract, Natural Flavors, Polymer Matrix, Citric Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: 3 sprays under tongue and swallow, up to 5 times daily. Shake before each use.
Storage
Best used 3 years from date on bottom.
Precautions
Warning: Do not use if safety seal is broken or missing.
Do not use if pregnant or nursing.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Earth's Bounty Est 1991 Wellness from our family to yours
Formulation
Youth enhancing formula
GF (Gluten free) Non GMO
Lifetime satisfaction guarantee
Formulated to be free from: Sugar Soy Preservatives
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
GMP Certified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Longevitrol by Earth's Bounty label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Longevitrol by Earth's Bounty
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Spray(s) Dosage formLiquid Servings per container61 Amounts shown are per serving.
Velvet Antler Extract
Interacts with52 drugs
Deer velvet is a traditional remedy made from the soft, growing antlers of deer or elk, and it is most often promoted for energy, athletic performance...
Velvet Antler Extract monograph & interactionsOther (inactive) ingredients: Water, Glycerin, Ascorbic Acid, Trace Mineral Complex, Maca Root Extract, Green Tea Leaf Extract, Natural Flavors, Polymer Matrix, Citric Acid. These complete the product’s ingredient list but are not active constituents.
Longevitrol by Earth's Bounty Drug Interactions
Longevitrol contains a single active ingredient, and it has known interactions with 52 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Longevitrol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Longevitrol interact with 52 drugs. Click any drug to see the details.
1 of the 1 ingredient in Longevitrol interact with drugs. Each result below shows which ingredient is responsible. Velvet Antler Extract
Ethinyl Estradiol, NorgestrelCryselle, Lo/Ovral, Low-Ogestrel, Ogestrel 0.5/50, Ovral
How Ethinyl Estradiol, Norgestrel interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs, Estrogens Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Ethinyl Estradiol, Norgestrel interactionEthinyl Estradiol, LevonogestrelLybrel
How Ethinyl Estradiol, Levonogestrel interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs, Estrogens Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Ethinyl Estradiol, Levonogestrel interactionEthynodiol Diacetate, MestranolOvulen
How Ethynodiol Diacetate, Mestranol interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Ethynodiol Diacetate, Mestranol interactionEtonogestrelImplanon
How Etonogestrel interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Etonogestrel interactionEtonogestrel, Ethinyl EstradiolNuvaRing
How Etonogestrel, Ethinyl Estradiol interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens, Contraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Etonogestrel, Ethinyl Estradiol interactionGestodeneMinesse
How Gestodene interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Gestodene interactionLactic Acid, Citric Acid, Potassium BitartratePhexxi
How Lactic Acid, Citric Acid, Potassium Bitartrate interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Lactic Acid, Citric Acid, Potassium Bitartrate interactionLevonorgestrelKyleena, Levonelle 1500, Levonelle One Step, Liletta, Mirena, Norgeston +2 more
How Levonorgestrel interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Levonorgestrel interactionLevonorgestrel, Ethinyl EstradiolLogynon ED, Microgynon 30, Nordette, Ovranette, Quartette, Trinordiol +1 more
How Levonorgestrel, Ethinyl Estradiol interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens, Contraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Levonorgestrel, Ethinyl Estradiol interactionMedroxyprogesterone Acetate, Oestrogens, ConjugatedPremique
How Medroxyprogesterone Acetate, Oestrogens, Conjugated interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Medroxyprogesterone Acetate, Oestrogens, Conjugated interactionMestranol, NorethindroneNecon 1/50, Nelova 1/50M, Norethin 1/50, Norethin 1/50M, Norinyl 1 50 21 Day, Ortho Novum 1 Plus 50 +2 more
How Mestranol, Norethindrone interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Mestranol, Norethindrone interactionMestranol, NorethynodrelEnovid-E
How Mestranol, Norethynodrel interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Mestranol, Norethynodrel interactionNorelgestromin, Ethinyl EstradiolEvra, Ortho Evra
How Norelgestromin, Ethinyl Estradiol interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs, Estrogens Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Norelgestromin, Ethinyl Estradiol interactionNorethindrone Acetate, Ethinyl Estradiol, Ferrous FumarateLoMinastrin FE, Minastrin 24 FE
How Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs, Estrogens Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interactionNorgestrelOrval 21, Ovrette
How Norgestrel interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Norgestrel interactionOestrogenOestrogen
How Oestrogen interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Oestrogen interactionPrasterone (prescription Drug)Intrarosa
How Prasterone (prescription Drug) interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Prasterone (prescription Drug) interactionRelugolix, Estradiol, Norethindrone AcetateMyfembree
How Relugolix, Estradiol, Norethindrone Acetate interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Relugolix, Estradiol, Norethindrone Acetate interactionSegesterone Acetate, Ethinyl EstradiolAnnovera
How Segesterone Acetate, Ethinyl Estradiol interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens, Contraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Segesterone Acetate, Ethinyl Estradiol interactionTiboloneLivial
How Tibolone interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Tibolone interactionUlipristal AcetateElla
How Ulipristal Acetate interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractContraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Read the full Velvet Antler Extract + Ulipristal Acetate interactionDrospirenone, Ethinyl Estradiol, LevomefolateBeyaz
How Drospirenone, Ethinyl Estradiol, Levomefolate interacts with Longevitrol — through 1 ingredient. Tap an ingredient for the detail:
Velvet Antler ExtractEstrogens, Contraceptive Drugs Minor
Interaction Summary
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Read the full Velvet Antler Extract + Drospirenone, Ethinyl Estradiol, Levomefolate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Longevitrol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Velvet Antler Extract
Contraceptive Drugs
Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Laboratory research shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.
Estrogens
Theoretically, deer velvet might increase the effects and side effects of estrogens.
Laboratory evidence shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.
Brand information
Manufacturer and brand details for Longevitrol, from the product label.
Earth's Bounty
See all Earth's Bounty products- Name
- Earth's Bounty
- City
- Flagler Beach
- State
- FL
- ZipCode
- 32136
- Phone Number
- (800) 736-5609
- Web Address
- earthsbounty.com
Longevitrol by Earth's Bounty: Common Questions
Does Longevitrol by Earth's Bounty interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Longevitrol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Longevitrol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Longevitrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Deer Velvet 2 references
- Sleivert, G., Burke, V., Palmer, C., Walmsley, A., Gerrard, D., Haines, S., and Littlejohn, R. The effects of deer antler velvet extract or powder supplementation on aerobic power, erythropoiesis, and muscular strength and endurance characteristics. Int PubMed
- Bubenik, G. A., Miller, K. V., Lister, A. L., Osborn, D. A., Bartos, L., and van der Kraak, G. J. Testosterone and estradiol concentrations in serum, velvet skin, and growing antler bone of male white-tailed deer. J Exp Zoolog.A Comp Exp Biol 3-1-2005;30 PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC