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Dietary supplement

Lutein Ingredients & Drug Interactions

by Member's Mark

Lutein label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein is a dietary supplement by Member's Mark with 1 active ingredient. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lutein by Member's Mark

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein by Member's Mark — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lutein by Member's Mark

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Lutein” is listed as a grouped ingredient — the label gives one combined amount (20 mg) without saying how much of each component you get.

This softgel contains one active ingredient: lutein, a yellow plant pigment that works alongside zeaxanthin, another carotenoid your eyes naturally contain. Both are thought to protect the tissue at the back of your eye.

The softgel itself is wrapped in gelatin and filled with vegetable oil, glycerin, soy lecithin, and yellow beeswax—all inactive ingredients that help the lutein dissolve and stay stable.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Promotes eye health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Zeaxanthin is rated "Insufficient Reliable Evidence To Rate" for Cataracts, Glaucoma, Asthenopia (eye strain), Macular telangiectasia type 2.

The evidence best supports lutein and zeaxanthin for age-related macular degeneration (AMD), where the data rates them possibly effective. For age-related cognitive decline, Alzheimer disease, asthma, breast cancer, and bronchopulmonary dysplasia, the evidence isn't yet strong enough to rate.

That doesn't mean they don't work for those uses—just that we don't have reliable data yet in the sources we hold.

The evidence, ingredient by ingredient Lutein Zeaxanthin

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein is generally well tolerated at the doses you'll find in supplements. If you're pregnant or breastfeeding, food sources of lutein are fine, but safety data on concentrated supplements isn't complete.

The facts show it's likely safe in pregnancy and lactation, though the caution here is that supplement-specific evidence isn't as solid as food evidence. Talk with your doctor or pharmacist about whether this supplement is right for you during pregnancy or while nursing.

Side effects, ingredient by ingredient Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs, check with your doctor or pharmacist before starting this product. The zeaxanthin it contains may increase your risk of low blood sugar (hypoglycemia).

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Member's Mark Lutein is aimed at people concerned about eye health, especially age-related macular degeneration. If you take diabetes medication, clear this with your doctor or pharmacist first—the zeaxanthin in it may theoretically increase low blood sugar risk.

It's generally well tolerated, and the dose appears reasonable for its purpose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein, straight from the product label.

Brand Member's Mark
Barcode (UPC) 681131004916
Net contents 150 Softgel(s)
Market status On market
Date entered into DSLD Aug 24, 2012
DSLD ID 12253
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein by Member's Mark, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
681131004916
IngredientAmount% DV
Lutein20 mg--
Contains Zeaxanthin800 mcg--

Other ingredients: Vegetable oil, Gelatin, Glycerin, yellow Beeswax, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

LABORATORY TESTED QUALITY ASSURED

M(R)

General

Prod. No. 4896 B4900 03B

General Statements

Promotes Eye Health

- 20 mg per Softgel - 1 Softgel Daily - Natural Carotenoid

Actual Size

FRESHNESS & POTENCY GUARANTEED THROUGH:

- NUTRITION INFORMATION: Lutein plays a role in the maintenance of eye health and is the principal Carotenoid found in the central area of the retina called the macula. Carotenoids are fat-soluble antioxidants found in fruits, vegetables, marigolds and other plants. Zeaxanthin, which is a carotenoid found in the macula of healthy eyes, is naturally-occurring in lutein.

Formula

- Naturally contains Zeaxanthin

Suggested/Recommended/Usage/Directions

Suggested Use: For adults, take one (1) softgel daily, preferably with the meal. As a reminder, discuss the supplements and medications you take with you health care providers.

Precautions

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

KEEP OUT OF THE REACH OF CHILDREN.

Tamper Resistant: Do not use if seal under cap is broken or missing.

Brand IP Statement(s)

Our Promise Offering premium quality products at an exceptional value is our ongoing commitment to you. Independent testing guarantees that this and every Member's Mark(R) product meets or exceeds the quality and performance levels of the leading national brand. Your satisfaction is guaranteed every time you use this product. For questions or comments regarding this product, visit membersmark.com or call toll free in the continental U.S. 1-888-667-8678, 8 a.m. to 5 p.m. CST Monday through Friday.

FDA Statement of Identity

DIETARY SUPPLEMENT

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Keep in a dry place, tightly closed and avoid excessive heat.

Formulation

No yeast No wheat No milk or milk derivatives No lactose No sugar No preservatives No artificial color No artificial flavor No sodium (less than 5 mg per serving).

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein by Member's Mark label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein by Member's Mark

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lutein

No known
interactions
20 mg per serving

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Vegetable oil, Gelatin, Glycerin, Yellow Beeswax, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein by Member's Mark Drug Interactions

Want to check YOUR meds against Lutein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Lutein interact with 86 drugs. Click any drug to see the details.

0 of the 1 ingredient in Lutein interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Lutein, from the product label.

Member's Mark

Name
SAM'S WEST, INC.
Street Address
608 S.W. 8th Street
City
Bentonville
State
AR
ZipCode
72716-0745
Pharmacist Counseling Corner

Lutein by Member's Mark: Common Questions

Does Lutein by Member's Mark interact with any medications?
Yes. Based on its ingredients, Lutein has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is lutein and why is it in this supplement?
Lutein is a yellow pigment found in plants and in your eye tissue. It's included because research suggests it may help protect the light-sensitive tissue at the back of your eye (the retina), especially as you age. Zeaxanthin, another carotenoid also in this product, works alongside lutein for the same purpose.
Does this supplement actually prevent age-related macular degeneration?
The evidence rates lutein and zeaxanthin as possibly effective for age-related macular degeneration (AMD). That means there's some good evidence, but it's not airtight. Talk with your eye doctor about whether this is the right choice for your eye health and whether it fits with any other treatments.
Is it safe to take if I'm pregnant or breastfeeding?
The facts show it's likely safe in pregnancy and lactation, but the evidence is based mostly on food sources, not concentrated supplements. Since data on the supplement specifically during pregnancy and nursing isn't complete, talk with your doctor or pharmacist before taking it—they know your situation best.
Can I take this with my diabetes medication?
You need to check with your doctor or pharmacist first. The zeaxanthin in this product may theoretically increase your risk of low blood sugar when combined with antidiabetes drugs, though the risk is based on theory and animal studies rather than proven harm in people. Your provider can help you decide whether it's safe for you.
What are the inactive ingredients?
The softgel contains vegetable oil, gelatin, glycerin, yellow beeswax, and soy lecithin. These help dissolve and stabilize the lutein; they're not active ingredients. If you have a soy allergy, note that soy lecithin is present.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein label
Go deeper

The Full Monographs Behind Lutein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph →
Sources

Sources & How We Checked

Lutein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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