No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Lutein-Plus Ingredients & Drug Interactions

by Douglas Laboratories

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Lutein-Plus is a dietary supplement by Douglas Laboratories with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lutein-Plus by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Lutein-Plus contains two active ingredients: lutein and a green base proprietary blend. Lutein is a carotenoid — a naturally occurring pigment found in leafy greens and other plants — that concentrates in the eye, particularly the macula, the part responsible for sharp central vision.

The green base proprietary blend is listed but we don't have a full ingredient breakdown for it. The capsule itself is made from gelatin, cellulose, and vegetable stearate, which are inactive ingredients that hold the formula together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye health and vision support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Lutein is rated "Insufficient Reliable Evidence To Rate" for Diabetic retinopathy, Dry eye, Glaucoma, Myopia, and more.

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts — the two eye conditions where there's enough evidence to suggest it may help, though more research is ongoing. For retinitis pigmentosa, retinopathy of prematurity, bronchopulmonary dysplasia, and necrotizing enterocolitis, lutein has been rated possibly ineffective, meaning the current evidence doesn't support its use.

The evidence base we have doesn't establish whether the green base proprietary blend contributes to or changes these ratings.

The evidence, ingredient by ingredient Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein from food and typical supplement doses is generally well tolerated. In clinical trials, doses up to 20 mg daily have not produced adverse effects.

The caution here is that most safety data comes from food sources and studied supplement doses; long-term safety data at higher supplement doses is still limited, so it's worth checking with your doctor before starting, especially if you're taking it long-term. Lutein is naturally present in breast milk, but safety of supplement doses in pregnancy and lactation isn't well studied — the rating is "Likely Safe," but talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Lutein

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. That said, we couldn't verify the green base proprietary blend.

If you're on any regular medications or have questions, run them through the checker on this page or ask your doctor or pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Lutein-Plus may be worth considering if you're concerned about age-related macular degeneration or cataracts, as the evidence suggests lutein is possibly effective for both. It's generally well tolerated and has no documented drug interactions in our data.

Before you start, especially if you're pregnant, nursing, or taking other supplements long-term, check with your doctor or pharmacist to make sure it fits your individual health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein-Plus, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539009284
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 10127
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein-Plus by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
310539009284
IngredientAmount% DV
Lutein20 mg--
Green base proprietary blend35 mg--

Other ingredients: Gelatin, Cellulose, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Precautions

Tamper resistant package, do not use if outer seal is missing.

KEEP OUT OF REACH OF CHILDREN.

General

Formula #83031

FDA Statement of Identity

A Dietary Supplement

Formulation

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by physician.

General Statements

Due to our cold process manufacturing methods, high temperature "wet" granulation is not used. Consequently, due to color and density differences of the ingredients, this product may have a non-homogenous appearance. This appearance is only cosmetic and does not effect the quality or consistency of this product.

See for yourself

Lutein-Plus by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lutein-Plus by Douglas Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
20 mg per serving Form: Marigold

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Green base proprietary blend

35 mg per serving Form: Broccoli, Celery, Collard Greens, Kale, Radish, Spinach, Turnip

Other (inactive) ingredients: Gelatin, Cellulose, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein-Plus by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lutein-Plus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lutein-Plus, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Lutein-Plus by Douglas Laboratories: Common Questions

Does Lutein-Plus by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lutein-Plus. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lutein-Plus contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is lutein and why is it in this supplement?
Lutein is a pigment found naturally in leafy greens and other plants that builds up in the eye, especially in the macula — the part that handles your sharpest vision. Research suggests it may help protect against age-related macular degeneration and cataracts.
Is it safe to take lutein long-term?
Lutein from food and typical supplement doses is generally well tolerated, and doses up to 20 mg daily haven't caused adverse effects in trials. However, long-term safety data at higher supplement doses is still limited, so it's worth checking with your doctor before you commit to it long-term.
Can I take this if I'm pregnant or breastfeeding?
Lutein is rated "Likely Safe" in pregnancy and lactation. It's naturally present in breast milk. That said, safety data on supplement doses specifically isn't complete, so talk with your doctor or pharmacist for personalized advice based on your situation.
Will this help my cataracts or macular degeneration?
Lutein is rated possibly effective for both age-related macular degeneration and cataracts, meaning there's some evidence it may help — but research is still ongoing and results aren't guaranteed. Talk with your eye doctor about whether it's right for you.
Does this interact with my medications?
No interactions are documented in our data for the ingredients we checked. We couldn't verify the green base proprietary blend. If you take regular medications, run them through the checker on this page or ask your doctor or pharmacist to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein-Plus is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein-Plus label
Go deeper

The Full Monographs Behind Lutein-Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lutein-Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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