No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Lutein-Plus Ingredients & Drug Interactions

by Douglas Laboratories

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Lutein-Plus is a dietary supplement by Douglas Laboratories with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lutein-Plus by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Lutein-Plus contains 2 active ingredients. Lutein is a carotenoid — a type of plant pigment — that concentrates in the eye, particularly in the macula (the center of the retina where sharp vision happens).

The product also includes a green base proprietary blend; the manufacturer hasn't disclosed the specific ingredients in that blend on this label. The inactive ingredients are gelatin, cellulose, and vegetable stearate — typical capsule and binding materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye health and macular degeneration support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Lutein is rated "Insufficient Reliable Evidence To Rate" for Diabetic retinopathy, Dry eye, Glaucoma, Myopia, and more.

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts, two common eye conditions linked to aging. The evidence for other uses — retinitis pigmentosa, retinopathy of prematurity, necrotizing enterocolitis, and bronchopulmonary dysplasia — is currently considered possibly ineffective in our data.

The strength of the evidence for AMD and cataracts is "possibly effective," which means there's some promising data but it's not conclusive.

The evidence, ingredient by ingredient Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein from foods and typical supplement doses is generally well tolerated. Studies show doses up to 20 mg daily haven't caused adverse effects in trial participants.

However, the safety data we hold notes there isn't enough information on higher supplement doses compared to food sources, so check with your doctor if you're pregnant, nursing, or have concerns about dosing. Lutein is naturally present in breast milk, but safety of elevated supplement doses during nursing isn't well studied.

Side effects, ingredient by ingredient Lutein

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the lutein we could check. We have no interaction data for the green base proprietary blend, so if you take any regular medications, ask your pharmacist to verify the blend's ingredients against your drug list.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have AMD or cataracts and want to explore lutein supplementation, this product is generally well tolerated and supported by some evidence. Pregnant or nursing?

There isn't enough safety data on supplement doses, so talk to your doctor or pharmacist first. Because this product includes a proprietary blend we couldn't check, ask your pharmacist if you're on medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein-Plus, straight from the product label.

Brand Douglas Laboratories
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2012
DSLD ID 5335
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein-Plus by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Lutein20 mg--
Green base proprietary blend35 mg--

Other ingredients: Gelatin, Cellulose, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by your healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0) - 77(0)F/15(0) - 25(0)C) (35-65% relative humidity)

General

Formula #83031

Formulation

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

See for yourself

Lutein-Plus by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lutein-Plus by Douglas Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
20 mg per serving Form: Marigold

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Green base proprietary blend

35 mg per serving Form: Broccoli, Celery, Collard Greens, Kale, Radish, Spinach, Turnip

Other (inactive) ingredients: Gelatin, Cellulose, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein-Plus by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lutein-Plus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lutein-Plus, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Lutein-Plus by Douglas Laboratories: Common Questions

Does Lutein-Plus by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lutein-Plus. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lutein-Plus contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's lutein, and why is it in an eye supplement?
Lutein is a plant pigment that builds up naturally in your eye, especially in the macula — the spot you use for sharp, focused vision. It may help protect that tissue from age-related damage.
Can I take this if I'm pregnant or breastfeeding?
Pregnancy is rated as likely safe based on the data we hold. Breastfeeding is more uncertain — lutein is naturally in breast milk, but we don't know if high supplement doses are safe during nursing. Talk to your OB or pharmacist for personalized advice.
Does lutein actually prevent or treat cataracts or macular degeneration?
It's possibly effective for both — meaning there's some supporting evidence, but it's not conclusive. If you have either condition, it's worth discussing with your eye doctor whether this fits your plan.
Are there any side effects?
Lutein at typical doses is generally well tolerated. Studies didn't find adverse effects at 20 mg daily, which is higher than most supplements.
What's the green base proprietary blend?
We don't have the specific ingredients listed, so we can't check it for interactions or side effects. Ask Douglas Laboratories for the full ingredient list if you want to verify it with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein-Plus is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein-Plus label
Go deeper

The Full Monographs Behind Lutein-Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lutein-Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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