Lymph Formula Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Lymph Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lymph Formula is a dietary supplement by Woodstock Herbal Products with 4 active ingredients. Its ingredients are commonly taken for digestive upset, antimicrobial support, blood sugar support.Based on those ingredients, 1,210 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Barberry root bark extract, Mullein Leaf Extract, Lobelia Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Lymph Formula by Woodstock Herbal Products
Ask about any prescription or over-the-counter medication and we check it for interactions with Lymph Formula by Woodstock Herbal Products — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Lymph Formula by Woodstock Herbal Products
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Lymph Formula has 4 active ingredients. The product contains a proprietary extract blend as its base, plus Barberry root bark extract, Mullein Leaf Extract, and Lobelia (in both aerial parts and seed extract forms).
These are blended into a liquid with apple cider vinegar and alcohol as inactive ingredients.
Does it work?
Couldn't assess
The evidence on these ingredients is limited. Mullein is listed with insufficient reliable evidence for bronchitis, asthma, cough, migraine headache, and diarrhea.
Lobelia is rated as possibly ineffective for smoking cessation. The data we hold doesn't establish that this product works for any condition.
How safe is it?
Well-documented data
Mullein is generally well tolerated for short-term use, but human safety data are limited overall. However, there are rare case reports of dermatitis from direct plant contact or inhalation of plant dust.
Lobelia carries stronger caution: it can be toxic and cause serious effects at higher doses. Doses as low as 50 mg have caused nausea, vomiting, diarrhea, coughing, dizziness, tremors, and throat irritation.
At 600 mg or higher, lobelia toxicity can cause rapid heart rate, low blood pressure, convulsions, loss of body heat, and potentially death. Because of this toxicity risk, lobelia is not advised during pregnancy or while breastfeeding.
Meds to double-check
Moderate interaction found
If you take lithium for mood disorders, do not start this product without talking to your pharmacist or doctor — lobelia may raise lithium levels to unsafe ranges. If you take blood thinners (warfarin, aspirin, or others), check first; mullein may add a mild blood-thinning effect.
Barberry root bark extract could not be checked — we hold no interaction data for it.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is not established to work for any condition in the data we hold. If you take lithium or blood thinners, check with your pharmacist before starting — this formula may require dose adjustments or shouldn't be used at all.
If you're pregnant or breastfeeding, the safety data advise against it, especially because of the lobelia content.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lymph Formula, straight from the product label.
| Brand | Woodstock Herbal Products |
|---|---|
| Barcode (UPC) | 854245005401 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 335082 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lymph Formula by Woodstock Herbal Products, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 440 mg | -- |
| Barberry root bark extract | 0 NP | -- |
| Mullein Leaf Extract | 0 NP | -- |
| Lobelia Aerial Parts Extract | 0 NP | -- |
| Lobelia Seed Extract | 0 NP | -- |
Other ingredients: Apple Cider Vinegar, Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
Certified Vegan V Vegan.org KOF-K (Kosher) Parve
Formulation
Certified Vegan V Vegan.org
Gluten Free
Traditionally Handcrafted Traditional Handcrafted Herbal Formula
Formula
KOF-K (Kosher) Parve
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: Shake well before each use. Take 10-25 drops in water or juice 2 to 5 times per day.
Precautions
Warning: Keep out of reach of children.
Do not use if safety seal is damaged or missing.
If you are pregnant, nursing, taking any medications, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.
Brand IP Statement(s)
Copyright 2016 Woodstock Herbal Products
General Statements
For product information, call (855) 573-1273.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lymph Formula by Woodstock Herbal Products label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lymph Formula by Woodstock Herbal Products
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.2 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
Other (inactive) ingredients: Apple Cider Vinegar, Alcohol. These complete the product’s ingredient list but are not active constituents.
Lymph Formula by Woodstock Herbal Products Drug Interactions
HelloPharmacist Interaction Report
Lymph Formula by Woodstock Herbal Products contains two ingredients with documented drug interactions.
Lobelia (present as both aerial parts and seed extract) has a Moderate interaction with lithium — a mood-stabilizing medication used for bipolar disorder. Lobelia's diuretic properties may reduce how your kidneys clear lithium from your body, potentially raising lithium levels to unsafe ranges; your dose might need adjustment if you take both.
Read the full breakdown — every affected drug type, severity by severity
Mullein Leaf Extract has a Minor interaction with anticoagulant and antiplatelet drugs (blood thinners like warfarin or aspirin). Lab studies show mullein extracts can mildly lengthen clotting time, which theoretically could add to the blood-thinning effect of these medications, though the effect appears mild.
We couldn't check Barberry root bark extract — we don't hold interaction data for it. Altogether, these interactions span 123 individual medications.
Use the medication checker below to search your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Lymph Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Lymph Formula interact with 1,210 drugs. Click any drug to see the details.
3 of the 4 ingredients in Lymph Formula interact with drugs. Each result below shows which ingredient is responsible. Barberry root bark extract Mullein Leaf Extract Lobelia Aerial Parts Extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Lymph Formula — through 2 ingredients. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Root Bark Extract + Abciximab interactionMullein Leaf ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein Leaf Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Lymph Formula — through 2 ingredients. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Root Bark Extract + Abrocitinib interactionMullein Leaf ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein Leaf Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Barberry Root Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Root Bark Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Lymph Formula — through 2 ingredients. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Root Bark Extract + Acenocoumarol interactionMullein Leaf ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein Leaf Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Root Bark Extract + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Lymph Formula — through 2 ingredients. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Root Bark Extract + Acetaminophen, Aspirin interactionMullein Leaf ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein Leaf Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Lymph Formula — through 2 ingredients. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Root Bark Extract + Acetaminophen, Aspirin, Caffeine interactionMullein Leaf ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot.
Read the full Mullein Leaf Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCns Depressants, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticholinergic Drugs, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Lymph Formula — through 1 ingredient. Tap an ingredient for the detail:
Barberry Root Bark ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Root Bark Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Lymph Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Barberry root bark extract
Anticholinergic Drugs
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Anticoagulant/Antiplatelet Drugs
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal evidence suggest that berberine, a constituent of European barberry, might inhibit platelet aggregation. Theoretically, European barberry might have a similar effect.
Antidiabetes Drugs
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical evidence suggests that European barberry juice reduces fasting glucose levels in patients with type 2 diabetes who are also taking antidiabetes drugs. Additionally, some animal studies show that berberine, a constituent of European barberry, has antiglycemic potential. Monitor blood glucose levels closely.
Antihypertensive Drugs
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Animal and human research suggests that European barberry extracts can have hypotensive effects.
Cholinergic Drugs
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Cns Depressants
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Animal research suggests that berberine, a constituent of European barberry, might have sedative effects. Theoretically, European barberry might have a similar effect.
Cyclosporine (Neoral, Sandimmune)
Theoretically, concomitant use with cyclosporine may cause additive effects.
Berberine, a constituent of European barberry, can reduce the metabolism and increase serum levels of cyclosporine. This effect is attributed to the ability of berberine to inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, European barberry might have a similar effect.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
There is very preliminary evidence suggesting that berberine, a constituent of European barberry, might inhibit the CYP3A4 enzyme. Theoretically, European barberry might have a similar effect.
Mullein Leaf Extract
Anticoagulant/Antiplatelet Drugs
Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.
Lobelia Aerial Parts Extract
Lithium
Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Lymph Formula, from the product label.
Woodstock Herbal Products
See all Woodstock Herbal Products products- Name
- Woodstock Herbal Products LLC
- City
- Woodstock
- State
- NY
- ZipCode
- 12498
- Phone Number
- 855-573-1273
- Web Address
- www.woodstockherbalproducts.com
Lymph Formula by Woodstock Herbal Products: Common Questions
Does Lymph Formula by Woodstock Herbal Products interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or nursing?
What's lobelia, and why is it a concern?
What does mullein do in here?
What are the inactive ingredients?
Is this safe to use with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lymph Formula is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lymph Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
European Barberry
Interacts with 1,210 drugsEuropean barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolated form. Some early research on berberine is promi...
Read the full European Barberry monograph → Herb & supplement monographMullein
Interacts with 122 drugsMullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...
Read the full Mullein monograph → Herb & supplement monographLobelia
Interacts with 1 drugLobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...
Read the full Lobelia monograph →Sources & How We Checked
Lymph Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
European Barberry 15 references
- Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
- Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
- Shamsa F, Ahmadiani A, Khosrokhavar R. Antihistaminic and anticholinergic activity of barberry fruit (Berberis vulgaris) in the guinea-pig ileum. J Ethnopharmacol 1999;64:161-6. PubMed
- Fatehi M, Saleh TM, Fatehi-Hassanabad Z, et al. A pharmacological study on Berberis vulgaris fruit extract. J Ethnopharmacol 2005;102:46-52. PubMed
- Kostalova, D., Bukovsky, M., Koscova, H., and Kardosova, A. [Anticomplement activity of Mahonia aquifolium bisbenzylisoquinoline alkaloids and berberine extract]. Ceska.Slov.Farm 2001;50(6):286-289.
- Fatehi-Hassanabad, Z., Jafarzadeh, M., Tarhini, A., and Fatehi, M. The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats. Phytother Res 2005;19(3):222-225.
- Singh, J. and Kakkar, P. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol. 5-4-2009;123(1):22-26. PubMed
- Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. B. Pharmacological actions of berberine on the central nervous system. Jpn.J Pharmacol 1970;20(4):482-487. PubMed
- Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102.
- Xuan, B., Wang, W., and Li, D. X. Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. Zhongguo Yao Li Xue.Bao. 1994;15(2):133-135.
- Gao, C. R., Zhang, J. Q., and Huang, Q. L. [Experimental study on berberin raised insulin sensitivity in insulin resistance rat models]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1997;17(3):162-164. DOI
- Sabir M and Bhide NK. Study of some pharmacological actions of berberine. Ind J Physiol & Pharmac 1971;15(3):111-132.
- Tripathi YB and Shukla SD. Berberis artistata inhibits PAF induced aggregation of rabbit platelets. Phytotherapy Research 1996;10:628-630.
- Lazavi F, Mirmiran P, Sohrab G, Nikpayam O, Angoorani P, Hedayati M. The barberry juice effects on metabolic factors and oxidative stress in patients with type 2 diabetes: A randomized clinical trial. Complement Ther Clin Pract. 2018;31:170-174. PubMed
- Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed
Mullein 2 references
- Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
- Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.
Lobelia 6 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
- Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
- Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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