Magnesium Acetyl-Tuarate 700 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Magnesium Acetyl-Tuarate 700 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Magnesium Acetyl-Tuarate 700 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for preventing or treating magnesium deficiency, constipation, muscle cramps.Based on those ingredients, 295 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Magnesium Acetyl-Taurate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements
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HelloPharmacist Scorecard of Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: magnesium in the form of magnesium acetyl-taurate, supplying 700 mg per capsule. Magnesium is a mineral your body needs for muscle function, nerve signaling, and maintaining strong bones.
The capsule also contains inactive ingredients—gelatin, rice flour, and microcrystalline cellulose—which are standard binders and fillers.
Does it work?
Moderate evidence
Magnesium is effective for treating indigestion (dyspepsia), constipation, and magnesium deficiency (hypomagnesemia). It's also effective for preventing and treating pre-eclampsia, a serious high-blood-pressure condition in pregnancy—though that use requires medical supervision.
The evidence we hold does not establish effectiveness for other purposes.
How safe is it?
Well-documented data
Magnesium is generally well tolerated at recommended doses. The most common side effects from oral magnesium are diarrhea, stomach irritation, nausea, and vomiting—which is why some people use it as a gentle laxative.
Rarely, very high doses taken over a long time can form a mass (bezoar) in your stomach that causes nausea and loss of appetite. Magnesium is needed during pregnancy, but supplements should only be used under your doctor's guidance.
Normal dietary amounts are fine while breastfeeding, but talk with your doctor before adding a supplement. Very high cumulative doses over weeks or months have raised concerns about bone strength in rare cases, though this is not typical with normal supplemental use.
Meds to double-check
Major interaction found
Before you start, check your medications against these types: levodopa/carbidopa (Major severity), skeletal muscle relaxants, calcium channel blockers, potassium-sparing diuretics, sulfonylureas (diabetes drugs), quinolone antibiotics, and bisphosphonates (bone medications). If you take any of these, confirm with your doctor or pharmacist that it's safe to add magnesium.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Magnesium works well for indigestion, constipation, and correcting low magnesium levels. Anyone taking Parkinson's medication, muscle relaxants, certain heart medications, diabetes pills, or bone drugs should check with their doctor or pharmacist before using this product—the interactions can affect how well your medications work or increase their side effects.
Start by running your exact medications through the checker on this page, then discuss the results with your own healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Magnesium Acetyl-Tuarate 700 mg, straight from the product label.
| Brand | Double Wood Supplements |
|---|---|
| Barcode (UPC) | 859793007914 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 24, 2021 |
| DSLD ID | 255606 |
| Product type | Mineral |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Women (not pregnant or lactating), Adult Female (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Magnesium | 45.5 mg | 11% |
| Magnesium Acetyl-Taurate | 700 mg | -- |
Other ingredients: Gelatin, Rice Flour, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Product Info: TauroMag (Magnesium Acetyl Taurate) - a unique form of magnesium with brain bioavailable taurine - it may help relieve many normal symptoms of PMS including having a normal, healthy attitude, healthy stress levels, and healthy sleep cycles. TauroMag contains 6.5% elemental magnesium by weight. TauroMag is owned and exclusively distributed by AIDP Inc.
(Tauro Mag) 700 mg per serving
Suggested/Recommended/Usage/Directions
Suggested Use: As a supplement, take 2 capsules per day. It can be taken in the morning or night, with or without food.
Storage
Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
Proudly Made in USA
Formulation
Made with Non-GMO ingredients Gluten free
PMS relief supplement Support healthy mood and stress levels
FDA Statement of Identity
Dietary Supplement
Precautions
Warning: Consult your physician before use.
Do not use Magnesium Acetyl-Taurate if you are pregnant, nurisng, or under the age of 18 years of age.
Do not use Magnesium Acetyl-Taurate if you are pregnant, nurisng, or under the age of 18 years of age.
Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use Magnesium Acetyl-Taurate and operate heavy machinery until you know how it affects you.
Keep out of reach of children.
Do not exceed 6 capsules per day.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Magnesium Acetyl-Taurate
Interacts with295 drugs
Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...
Magnesium Acetyl-Taurate monograph & interactionsOther (inactive) ingredients: Gelatin, Rice Flour, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements Drug Interactions
HelloPharmacist Interaction Report
Magnesium Acetyl-Taurate 700 mg by Double Wood Supplements does interact with several medication types.
The most serious concern is with levodopa/carbidopa (Sinemet), a Parkinson's medication: magnesium can significantly reduce how much of the drug your body absorbs, cutting levodopa levels by about 35% and carbidopa by as much as 81%. This could make your medication less effective.
Read the full breakdown — every affected drug type, severity by severity
Magnesium also interacts moderately with skeletal muscle relaxants (it can strengthen their effects and speed up how quickly they work), calcium channel blockers used for heart rhythm and blood pressure (risk of severe low blood pressure), potassium-sparing diuretics that help your kidneys retain potassium (magnesium levels could climb too high), and sulfonylureas, older diabetes drugs (they can lower your blood sugar too much). Additionally, it reduces absorption of quinolone antibiotics and bisphosphonates (bone medications), and can interfere with how antacids work.
Altogether, these interactions span 295 individual medications. If you take any prescription medications, run them through the checker below before adding this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Magnesium Acetyl-Tuarate 700 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Magnesium Acetyl-Tuarate 700 mg interact with 295 drugs. Click any drug to see the details.
1 of the 1 ingredient in Magnesium Acetyl-Tuarate 700 mg interact with drugs. Each result below shows which ingredient is responsible. Magnesium Acetyl-Taurate
Benserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium Acetyl-taurate + Benserazide, Levodopa interactionCarbidopaLodosyn
How Carbidopa interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium Acetyl-taurate + Carbidopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium Acetyl-taurate + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium Acetyl-taurate + Carbidopa, Levodopa, Entacapone interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium Acetyl-taurate + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateLevodopa/carbidopa (sinemet) Major
Interaction Summary
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Read the full Magnesium Acetyl-taurate + Levodopa, Carbidopa interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium Acetyl-taurate + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium Acetyl-taurate + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium Acetyl-taurate + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium Acetyl-taurate + Acetaminophen, Methocarbamol interactionAcetaminophen, OrphenadrineOrfenagesic
How Acetaminophen, Orphenadrine interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium Acetyl-taurate + Acetaminophen, Orphenadrine interactionAcetohexamideDymelor
How Acetohexamide interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSulfonylureas Moderate
Interaction Summary
Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Read the full Magnesium Acetyl-taurate + Acetohexamide interactionAlcuroniumAlcuronium
How Alcuronium interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateSkeletal Muscle Relaxants Moderate
Interaction Summary
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Read the full Magnesium Acetyl-taurate + Alcuronium interactionAlendronateBinosto, Fosamax
How Alendronate interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateBisphosphonates Moderate
Interaction Summary
Magnesium can decrease absorption of bisphosphonates.
Read the full Magnesium Acetyl-taurate + Alendronate interactionAlendronate Sodium
How Alendronate Sodium interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateBisphosphonates Moderate
Interaction Summary
Magnesium can decrease absorption of bisphosphonates.
Read the full Magnesium Acetyl-taurate + Alendronate Sodium interactionAlendronate Sodium, CholecalciferolFosamax Plus D
How Alendronate Sodium, Cholecalciferol interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateBisphosphonates Moderate
Interaction Summary
Magnesium can decrease absorption of bisphosphonates.
Read the full Magnesium Acetyl-taurate + Alendronate Sodium, Cholecalciferol interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAntacids Moderate
Interaction Summary
Use of acid reducers may reduce the laxative effect of magnesium oxide.
Read the full Magnesium Acetyl-taurate + Alginic Acid, Aluminum Hydroxide interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAntacids Moderate
Interaction Summary
Use of acid reducers may reduce the laxative effect of magnesium oxide.
Read the full Magnesium Acetyl-taurate + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAnticoagulant/antiplatelet Drugs, Antacids Moderate
Interaction Summary
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
Read the full Magnesium Acetyl-taurate + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAnticoagulant/antiplatelet Drugs, Antacids Moderate
Interaction Summary
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
Read the full Magnesium Acetyl-taurate + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAntacids Moderate
Interaction Summary
Use of acid reducers may reduce the laxative effect of magnesium oxide.
Read the full Magnesium Acetyl-taurate + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAntacids Moderate
Interaction Summary
Use of acid reducers may reduce the laxative effect of magnesium oxide.
Read the full Magnesium Acetyl-taurate + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAntacids Moderate
Interaction Summary
Use of acid reducers may reduce the laxative effect of magnesium oxide.
Read the full Magnesium Acetyl-taurate + Aluminum, Magnesium (otc Drug) interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateAminoglycoside Antibiotics Moderate
Interaction Summary
Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Read the full Magnesium Acetyl-taurate + Amikacin interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-tauratePotassium-sparing Diuretics Moderate
Interaction Summary
Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Read the full Magnesium Acetyl-taurate + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-tauratePotassium-sparing Diuretics Moderate
Interaction Summary
Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Read the full Magnesium Acetyl-taurate + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium Acetyl-taurate + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium Acetyl-taurate + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium Acetyl-taurate + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Magnesium Acetyl-Tuarate 700 mg — through 1 ingredient. Tap an ingredient for the detail:
Magnesium Acetyl-taurateCalcium Channel Blockers Moderate
Interaction Summary
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Read the full Magnesium Acetyl-taurate + Amlodipine Besylate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Magnesium Acetyl-Tuarate 700 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Magnesium Acetyl-Taurate
Levodopa/Carbidopa (Sinemet)
Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.
Aminoglycoside Antibiotics
Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.
Antacids
Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.
Bisphosphonates
Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.
Calcium Channel Blockers
Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.
Digoxin
Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.
Potassium-Sparing Diuretics
Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.
Quinolone Antibiotics
Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.
Skeletal Muscle Relaxants
Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.
Sulfonylureas
Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.
Tetracycline Antibiotics
Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.
Anticoagulant/Antiplatelet Drugs
Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.
Gabapentin (Neurontin)
Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.
Sevelamer (Renagel, Renvela)
Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.
Brand information
Manufacturer and brand details for Magnesium Acetyl-Tuarate 700 mg, from the product label.
Double Wood Supplements
See all Double Wood Supplements products- Name
- Double Wood LLC
- Street Address
- 3510 Scotts Ln Ste 219
- City
- Philadelphia
- State
- PA
- ZipCode
- 19129-1573
- Web Address
- www.doublewoodsupplements.com
Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements: Common Questions
Does Magnesium Acetyl-Tuarate 700 mg by Double Wood Supplements interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my constipation?
Can I take magnesium if I'm pregnant?
What if I'm breastfeeding—is it okay?
Does magnesium help with heartburn or indigestion?
Can I take this with my antibiotics?
What are the side effects?
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The Full Monographs Behind Magnesium Acetyl-Tuarate 700 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Magnesium Acetyl-Tuarate 700 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 82 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Magnesium 82 references
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- Yagi T, Naito T, Mino Y, Umemura K, Kawakami J. Impact of concomitant antacid administration on gabapentin plasma exposure and oral bioavailability in healthy adult subjects. Drug Metab Pharmacokinet 2012;27(2):248-54. PubMed
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- Choi ES, Jeong WJ, Ahn SH, Oh AY, Jeon YT, Do SH. Magnesium sulfate accelerates the onset of low-dose rocuronium in patients undergoing laryngeal microsurgery. J Clin Anesth. 2017 Feb;36:102-106. PubMed
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC