Mangosteen Fruit 2% Extract Powder Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Mangosteen Fruit 2% Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Mangosteen Fruit 2% Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, anti-inflammatory support, immune support.Based on those ingredients, 125 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Mangosteen Fruit Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product is a single-ingredient supplement: mangosteen fruit extract powder, concentrated to 2% potency. There are no added inactive ingredients listed.
Mangosteen is a tropical fruit whose extract contains compounds called xanthones, which are believed to be the active components that give the supplement its effects.
Does it work?
Moderate evidence
The evidence for mangosteen is mixed. For periodontitis (gum disease), the data rates it as possibly effective — meaning there's some evidence, but it's not conclusive.
For androgenic alopecia (male-pattern hair loss), Alzheimer's disease, and atopic dermatitis (eczema), there isn't enough reliable evidence in our data to make a rating. If you're considering this for one of those conditions, talk it over with your doctor or pharmacist to see what the current research suggests.
How safe is it?
Well-documented data
Mangosteen extract is generally considered safe as a food, but long-term safety when taken as a concentrated supplement hasn't been well studied. Some people using mangosteen extract up to 560 mg daily have reported mild tiredness, headache, dizziness, malaise, constipation, nausea, vomiting, diarrhea, dry throat, cough, and flu-like symptoms — though it's unclear whether these were caused by mangosteen itself.
There isn't enough safety data on mangosteen during pregnancy or breastfeeding; the data advises against taking supplement amounts if you're pregnant or nursing. Talk with your doctor or pharmacist for personalized advice based on your situation.
Meds to double-check
Moderate interaction found
Before you start, double-check if you take any blood thinners or antiplatelet medications (like warfarin, clopidogrel, or aspirin) — mangosteen may increase bleeding risk. You should also verify whether you're on donepezil (Aricept) for Alzheimer's disease, since mangosteen might raise its brain levels.
If you're on any of these, clear it with your doctor or pharmacist first.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Mangosteen extract may help with gum disease, but the evidence is limited for other uses. If you take a blood thinner, antiplatelet drug, or donepezil, check with your doctor or pharmacist before starting this supplement — the interaction risk is real.
Pregnant or breastfeeding? Skip it until you've talked it over.
For anyone else, mild digestive or head-related effects are possible but not certain.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Mangosteen Fruit 2% Extract Powder, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435412609 |
| Net contents | 1 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Feb 21, 2023 |
| DSLD ID | 283790 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Mangosteen Fruit Extract, Powder | 1000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2020 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.
Mangosteen Fruit Extract, Powder
Interacts with125 drugs
Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supp...
Mangosteen Fruit Extract, Powder monograph & interactionsMangosteen Fruit 2% Extract Powder by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
TerraVita Premium Collection Mangosteen Fruit 2% Extract Powder contains mangosteen fruit extract, which has documented interactions with a significant number of medications.
The most serious interaction is with blood thinners and antiplatelet drugs (anticoagulants/antiplatelets) — there's a Moderate risk that mangosteen may increase bleeding when combined with these medications. This happens because a compound in mangosteen called gamma-mangostin appears to interfere with how your blood clots.
Read the full breakdown — every affected drug type, severity by severity
Mangosteen may also interact with donepezil (Aricept), a medication for Alzheimer's disease, though this is a Minor concern. Animal research suggests it could raise how much donepezil stays in your brain, potentially strengthening its effects.
Altogether, these interactions span 125 individual medications. Because this extract is derived from a single ingredient, the interaction profile is straightforward, but if you take any blood thinner, antiplatelet agent, or donepezil, run your exact medications through the checker below before you start this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Mangosteen Fruit 2% Extract Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Mangosteen Fruit 2% Extract Powder interact with 125 drugs. Click any drug to see the details.
1 of the 1 ingredient in Mangosteen Fruit 2% Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Mangosteen Fruit Extract, Powder
AbciximabReoPro
How Abciximab interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Mangosteen Fruit 2% Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Mangosteen Fruit Extract, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
Read the full Mangosteen Fruit Extract, Powder + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Mangosteen Fruit 2% Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Mangosteen Fruit Extract, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
In vitro and animal research shows that gamma-mangostin, a constituent of mangosteen, is a potent and competitive antagonist of the serotonin 2A (5-HT2A) receptor. Antagonism of the 5-HT2A receptor is believed to reduce platelet aggregation.
Donepezil (Aricept)
Theoretically, concomitant use of mangosteen with donepezil might increase the effects of donepezil.
Animal research shows that concomitant use of an aqueous extract of mangosteen pericarp with donepezil increases brain concentrations of donepezil at 4 hours by 64% without associated effects on systemic exposure.
Brand information
Manufacturer and brand details for Mangosteen Fruit 2% Extract Powder, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection: Common Questions
Does Mangosteen Fruit 2% Extract Powder by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is mangosteen fruit extract, and what is it supposed to do?
Can I take this if I'm pregnant or breastfeeding?
What side effects might I experience?
Is this safe to take long-term?
Does mangosteen interact with a lot of medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Mangosteen Fruit 2% Extract Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Mangosteen Fruit 2% Extract Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Mangosteen Fruit 2% Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Mangosteen 6 references
- Chairungsrilerd N, Furukawa K, Ohta T, et al. Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana. Planta Med 1996;62:471-2.
- Wong LP, Klemmer PJ. Severe lactic acidosis associated with juice of the mangosteen fruit Garcinia mangostana. Am J Kidney Dis 2008;51:829-33. PubMed
- Furukawa, K., Chairungsrilerd, N., Ohta, T., Nozoe, S., and Ohizumi, Y. [Novel types of receptor antagonists from the medicinal plant Garcinia mangostana]. Nippon Yakurigaku Zasshi 1997;110 Suppl 1:153P-158P. PubMed
- Chairungsrilerd, N., Furukawa, K., Tadano, T., Kisara, K., and Ohizumi, Y. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998
- Suthammarak W, Numpraphrut P, Charoensakdi R, et al. Antioxidant-enhancing property of the polar fraction of mangosteen pericarp extract and evaluation of its safety in humans. Oxid Med Cell Longev 2016;2016:1293036. PubMed
- Bae M, Han SY, Kim ES, et al. Effect of Water Extract of Mangosteen Pericarp on Donepezil Pharmacokinetics in Mice. Molecules 2021;26(17):5246. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC