Major interaction on record — check this product against your medications before combining. Based on 4 of 9 ingredients. Check your meds →
Dietary supplement

Mass-Peak Chocolate Ingredients & Drug Interactions

by Inner Armour

Powder Category: Other Combinations
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Mass-Peak Chocolate is a dietary supplement by Inner Armour with 9 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,148 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dietary Fiber, Sodium, Calcium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Mass-Peak Chocolate by Inner Armour

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 22 active ingredients.
  • “MASS-PEAK” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Carbo MASS” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Branched and Linear Chain Carbohydrate Restoration Complex” is a proprietary blend — the label doesn't break down how much of each component you get.

Mass-Peak Chocolate contains 21 ingredients overall. The active components include sodium, potassium, calcium, and chromium picolinate for mineral and micronutrient support.

The product also delivers whey protein — in the form of whey protein concentrate and whey protein isolate — as well as milk protein isolate and micellar casein phosphoprotein complex for muscle support. Additional active components include carbohydrate blends (alpha-1,4 linked glucose polymers and other carbohydrate restoration complexes) and specialized ingredients such as Cinnulin-PF and Carbogen.

The inactive ingredients are cocoa, xanthan gum, salt, natural and artificial flavors, acesulfame K, and sucralose.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle building and sports nutrition support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, muscle recovery, protein supplementation, strength training support.
  • The strongest evidence on file: Whey Protein is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.
  • Also on file: Whey Protein is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

Sodium is likely effective for cystic fibrosis and possibly effective for reducing kidney damage from the drug amphotericin B; evidence is insufficient to rate it for bipolar disorder or heart failure. Calcium is effective for kidney failure, heartburn (dyspepsia), low blood calcium (hypocalcemia), and high potassium (hyperkalemia), and likely effective for osteoporosis.

Chromium picolinate is likely effective for chromium deficiency and possibly effective for diabetes, but possibly ineffective for prediabetes, schizophrenia, and high blood pressure. Whey protein (in both concentrate and isolate forms) is possibly effective for athletic performance but possibly ineffective for osteoporosis and chronic obstructive pulmonary disease.

Casein protein has insufficient evidence for athletic performance, diabetes, chronic lung disease, and other conditions. Potassium, the carbohydrate blends, and the other proprietary components have no effectiveness ratings in our data.

The evidence, ingredient by ingredient Black Psyllium Sodium Potassium Calcium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 9 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is generally well tolerated at normal dietary amounts, but the data cautions against excess intake — high sodium is linked to high blood pressure and heart strain, and can worsen kidney disease. Potassium from food is fine, but supplements can cause dangerously high blood levels in people with kidney disease or those taking certain medications.

Calcium is generally well tolerated at recommended doses; high intakes carry rare but serious risks including kidney stones and calciphylaxis, and some concern exists about high doses and cardiovascular disease or prostate cancer, though evidence is mixed. Chromium is usually well tolerated at typical supplement doses, though high or long-term use may pose risks; adverse effects include gastrointestinal irritation, headaches, insomnia, and rarely kidney or liver damage.

Whey protein is generally well tolerated but may trigger or worsen acne in some people, and can cause bloating, diarrhea, nausea, and headache, especially at higher doses; one rare case linked it to coronary artery clots. Casein protein is generally well tolerated but may cause diarrhea, constipation, vomiting, or delayed stomach emptying; allergic reactions are rare but possible.

Side effects, ingredient by ingredient Black Psyllium Sodium Potassium Calcium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 8 of the 9 matched ingredients can interact with medications — Safflower, Black Psyllium, Calcium, Whey Protein, Potassium, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 2,149 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Mass-Peak Chocolate, double-check with your doctor or pharmacist if you take levodopa (for Parkinson disease) — this is the most serious interaction. Also flag blood pressure medications (ACE inhibitors, ARBs, and other antihypertensives), diabetes or insulin medications, lithium, HIV integrase inhibitors (dolutegravir, elvitegravir, raltegravir), thyroid medication (levothyroxine), corticosteroids, potassium-sparing diuretics, antibiotics (quinolones, tetracyclines, ceftriaxone, didanosine), bisphosphonates, NSAIDs or aspirin, and heart medications (sotalol, diltiazem).

No interactions are documented for several ingredient components we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Mass-Peak Chocolate is a multi-ingredient sports nutrition powder suited for people looking to gain muscle and weight with carbohydrate and protein support. However, if you take any blood pressure medications, diabetes drugs, HIV medications, thyroid medication, antibiotics, heart drugs, or medications for Parkinson disease, you need to check your exact prescriptions before starting this product — the interactions are real and potentially serious.

Talk with your doctor or pharmacist about whether this product is right for you and your current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 11 of 22 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mass-Peak Chocolate, straight from the product label.

Brand Inner Armour
Barcode (UPC) 183859201009
Net contents 8.8 lb; 4 kg
Market status On market
Date entered into DSLD Dec 23, 2011
DSLD ID 3575
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mass-Peak Chocolate by Inner Armour, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
173 Gram(s), 173 g
Maximum serving Sizes:
173 Gram(s), 173 g
Servings per container
23
UPC/BARCODE
183859201009
IngredientAmount% DV
Calories963 {Calories}, 671 {Calories}--
Total Carbohydrates124 Gram(s), 102 Gram(s)41%, 34%
Sugar29 Gram(s), 3 Gram(s)--
Calories from Fat207 {Calories}, 63 {Calories}--
Dietary Fiber0 Gram(s), 0 Gram(s)--
Protein66 Gram(s), 50 Gram(s)132%, 100%
Saturated Fat20 Gram(s), 2 Gram(s)100%, 10%
Sodium291 mg, 95 mg12%, 4%
Trans Fat0 Gram(s), 0 Gram(s)--
Potassium978 mg, 280 mg28%, 8%
Cholesterol126 mg, 75 mg42%, 25%
Calcium877 mg, 325 mg88%, 32%
Total Fat23 Gram(s), 7 Gram(s)35%, 10%
Chromium Picolinate0 NP, 0 NP--
Immunoglobulins0 NP, 0 NP--
Whey Protein concentrate0 NP, 0 NP--
MCT's0 NP, 0 NP--
MASS-PEAK0 NP, 0 NP--
Carbo MASS0 NP, 0 NP--
Branched and Linear Chain Carbohydrate Restoration Complex0 NP, 0 NP--
Alpha-1,4 Linked Glucose Polymers0 NP--
Glucose Transport and Lean Tissue Support Complex0 NP, 0 NP--
Cinnulin-PF0 NP, 0 NP--
Carbogen0 NP, 0 NP--
ProNitro 70 NP, 0 NP--
Grade A Full Spectrum Bioactive Whey Protein Complex0 NP, 0 NP--
Whey Protein isolate0 NP, 0 NP--
Di-Peptide0 NP, 0 NP--
Oligo Peptide0 NP, 0 NP--
Beta-Lactoglobulin0 NP, 0 NP--
Alpha-Lactalbumin0 NP, 0 NP--
Serum Albumin0 NP, 0 NP--
Micellar Casein Phosphoprotein Complex0 NP, 0 NP--
Milk Protein isolate0 NP, 0 NP--
Aminogen Elite Amino Acid Spiking Polypeptide Complex0 NP, 0 NP--
Omega 3-MCT0 NP, 0 NP--
Flax seed powder0 NP, 0 NP--
Safflower0 NP, 0 NP--

Other ingredients: Cocoa, Xanthan Gum, Salt, Natural and Artificial flavors, Acesulfame K, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

THIS IS A SPORTS FOOD SUPPLEMENT STRICTLY INTENDED FOR USE IN CONJUNCTION WITH A CALORIE AND NUTRIENT ADEQUATE DIET AND A STRUCTURED EXERCISE PROGRAM.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, mix 4 scoops with 14-16 oz of water or milk depending on your desired consistency. Use approximately 3.5-4oz of liquid for each scoop of MASS-PEAK. Additional servings may be used to meet your daily calorie and nutritional requirements.

Precautions

Keep out of reach of children.

NOT SUITABLE FOR CHILDREN UNDER 15 YEARS OR PREGNANT WOMEN.

CONSULT WITH A MEDICAL DOCTOR BEFORE USING IF YOU ARE UNAWARE OF YOUR HEALTH STATUS OR YOU HAVE A MEDICAL CONDITION.

Do not purchase if seal is broken.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store at 15-30*C (59-86*F). Protect from heat, light and moisture.

Formula

66g Protein - 25g Glutamine & BCAAs**

MASS-PEAK Amino Acid Profile 2 Servings With Whole Milk 132,000mg of Amino Acids Including: 24g Glutamine1 25g BCAAs (Leucine, Isoleucine and Valine) 1as Glutamic Acid

General Statements

#1 Rated Weight Gainer* Weight Gain - Muscle Growth - Recovery* Formulated for Pro, College and High School Athletes* Formulated With Zero Banned Substances***

***Our products are formulated without the use of substances banned by the FDA and leading sports organizations.

Chocolate Naturally and Artificially Flavored

IA Parisi MASSPEAK Choc USA 7/09

Manufactured at a GMP Registered Facility

Manufactured at an EU Certified Facility

Product of USA

Brand IP Statement(s)

AMINOGEN(R) is a Registered Trademark of Triarco Industries. AMINOGEN(R) is protected by U.S. Patent No. 5,387,422

CARBOGEN(R) is a Registered Trademark of Triarco Industries. CARBOGEN(R) is protected by U.S. Patent No. 5,817,350

WHY YOU NEED MASS-PEAK(TM): The higher your training (exercise) intensity, the faster you deplete your body of carbohydrates (glucose and glycogen), amino acids (the building blocks of protein), fat (triglycerides, consisting of fatty acids and glycerol), water and electrolytes (e.g. sodium, potassium). Your body’s #1 and #2 nutritional priorities are, in order, replacing carbohydrates and amino acids. Failure to replace carbohydrates can cause your body to catabolize (break down) muscle tissue resulting in serious losses of muscle mass, strength, speed and power. The MASS-PEAK formula mixes up with water or milk to create a delicious shake that begins addressing your body’s #1 and #2 priorities the instant you swallow it. Each serving drives lean carbohydrate (102 g) and protein calories (50 g) into your tired muscles accompanied by Essential Fatty Acids (EFAs), Medium-Chain Triglycerides (MCTs) (for fast energy) and Conjugated Linoleic Acid (CLA) (to preserve lean mass). The combined effect is to allow you to gain muscle mass, speed and strength incredibly faster and keep every pound of it thereafter. This protects and enhances your ability to sustain higher muscular forces at higher speeds, also known as “speed X strength”, or power. And when it comes to performance, power is what defines a great athlete.

Seals/Symbols

inner(R) Armour THE SPEED OF POWER(TM)

PARISI SPEED SCHOOL(TM) BANNED SUBSTANCE FREE*** APPROVED

PARISI(TM) Speed School Approved

General

IA Parisi MASSPEAK ChocUSA 7/09

See for yourself

Mass-Peak Chocolate by Inner Armour label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mass-Peak Chocolate by Inner Armour

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size173 Gram(s) Dosage formPowder Servings per container23 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

29 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs
0 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

66 Gram(s) per serving

Sodium

Interacts with
205 drugs
291 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
978 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Calcium

Interacts with
168 drugs
877 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

MASS-PEAK

0 NP per serving
  • › Carbo MASS
  • › ProNitro 7
  • › Omega 3-MCT

Other (inactive) ingredients: Cocoa, Xanthan Gum, Salt, Natural and Artificial flavors, Acesulfame K, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mass-Peak Chocolate by Inner Armour Drug Interactions

Want to check YOUR meds against Mass-Peak Chocolate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,148Drugs
12 Major 684 Moderate 1,452 Minor

Ingredients driving the most interactions

Sodium 205
Calcium 168

Each ingredient & the kinds of drugs it affects

For each ingredient in Mass-Peak Chocolate with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Mass-Peak Chocolate, from the product label.

Inner Armour

See all Inner Armour products
Name
IA Nutrition, Inc.
City
Cape Coral
State
FL
Web Address
www.innerarmour.com
Pharmacist Counseling Corner

Mass-Peak Chocolate by Inner Armour: Common Questions

Does Mass-Peak Chocolate by Inner Armour interact with any medications?
Yes. Based on its ingredients, Mass-Peak Chocolate has a known interaction with 2,148 medications, including 12 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mass-Peak Chocolate contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product contain whey protein?
Yes, it does. Mass-Peak Chocolate contains whey protein concentrate and whey protein isolate as active ingredients. If you're lactose-sensitive or allergic to milk, check the label or ask your pharmacist about the lactose content, since whey is a milk-derived protein.
Can I take this if I'm on blood pressure medication?
You'll need to check with your doctor or pharmacist first. This product contains sodium, which can reduce the effectiveness of blood pressure medications, and potassium and calcium, which can also interact with certain types of blood pressure drugs. Don't start without confirming it's safe with your specific medications.
Will this help me build muscle?
Whey protein is possibly effective for athletic performance, so it may support muscle building when combined with exercise and training. However, the data we hold doesn't establish whether the full product formula is effective for this goal — that depends on your training, diet, and individual response.
What are the most common side effects?
From the whey and casein protein components, the most common side effects are dose-related and include bloating, cramps, diarrhea, nausea, headache, and acne. From chromium, you might experience headaches, insomnia, or gastrointestinal upset. Most improve with lower doses or discontinuation.
Is this safe to use while pregnant or breastfeeding?
Safety data for the individual ingredients varies — some have limited data, and pregnancy and lactation safety ratings for whey, milk protein, and casein are not on file. Talk with your doctor or pharmacist about whether this product is appropriate for you during pregnancy or while breastfeeding.
Can I take this with my diabetes medication?
Chromium in this product may lower blood sugar levels, so combined with diabetes medications or insulin, there's a risk of dangerously low blood sugar (hypoglycemia). Check with your doctor or pharmacist before using this product alongside diabetes drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mass-Peak Chocolate label
Sources

Sources & How We Checked

Mass-Peak Chocolate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 320 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
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See these in context on the Black Psyllium monograph →

Sodium 38 references
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See these in context on the Sodium monograph →

Potassium 12 references
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See these in context on the Potassium monograph →

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See these in context on the Calcium monograph →

Chromium 53 references
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Flaxseed 37 references
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Safflower 14 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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