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Dietary supplement

MetaBiotic Ingredients & Drug Interactions

by MetaBiotic

MetaBiotic label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MetaBiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

MetaBiotic is a dietary supplement by MetaBiotic with 1 active ingredient. Its ingredients are commonly taken for digestive health and regularity, constipation relief, immune support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium animalis subsp. lactis BB-12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against MetaBiotic by MetaBiotic

Ask about any prescription or over-the-counter medication and we check it for interactions with MetaBiotic by MetaBiotic — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of MetaBiotic by MetaBiotic

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bifidobacterium Animalis Subsp. Lactis.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MetaBiotic, straight from the product label.

Brand MetaBiotic
Net contents 45 Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2018
DSLD ID 82869
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MetaBiotic by MetaBiotic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
45
IngredientAmount% DV
Bifidobacterium animalis subsp. lactis BB-126 mg--

Other ingredients: Maltodextrin, Microcrystalline Cellulose, Hypromellose, Sucrose, Water, Magnesium Stearate, Sodium Ascorbate, Titanium Dioxide, Gellan Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

New Make a change

6 week supply

Actual size

Multihealth Probiotic Benefits Wellness begins within! Did you know that approximately 70% of your immune system is located in the digestive tract? Probiotics helps maintain a healthy digestive tract.

Naturally helps promote a healthy immune system.

Naturally helps support digestive health.

Made in Denmark

Supplement Information

Formula

With Bio-Active 12, A 2 in 1 Multihealth Probiotic That Naturally Helps: Promote a healthy immune system Maintain digestive balance

MetaBiotic contains a celebrated bacteria strain, known as Bio-Active 12, which when included as part of your daily wellness routine, helps maintain a balanced and healthy immune system.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

MetaBiotic, from the makers of Metamucil, is a once daily probiotic supplement that you can add to your wellness regimen today.

Bio-Active 12 fortifies your digestive system with healthy bacteria and helps maintain digestive balance.

BB-12 is a registered trademark of Chr.Hansen

Suggested/Recommended/Usage/Directions

Directions: Take one capsule per day.

Storage

Store at room temperature. For best results, we recommend you store MetaBiotic in the original blister package.

Precautions

Caution: Parental supervision is recommended for use of MetaBiotic by children. Keep out of reach of children.

Tamper Evident: Carton sealed for your protection. Do not use if capsule blister unit is open or torn.

FDA Statement of Identity

Probiotic Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MetaBiotic by MetaBiotic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MetaBiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MetaBiotic by MetaBiotic

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Bifidobacterium animalis subsp. lactis BB-12

Interacts with
182 drugs
6 mg per serving

Bifidobacterium animalis subsp. lactis is a well-studied probiotic bacterium commonly added to supplements and yogurts to support digestion and gut he...

Bifidobacterium animalis subsp. lactis BB-12 monograph & interactions

Other (inactive) ingredients: Maltodextrin, Microcrystalline Cellulose, Hypromellose, Sucrose, Water, Magnesium Stearate, Sodium Ascorbate, Titanium Dioxide, Gellan Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

MetaBiotic by MetaBiotic Drug Interactions

MetaBiotic contains a single active ingredient, and it has known interactions with 182 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against MetaBiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium animalis subsp. lactis BB-12 182

Individual Drug Interactions

The ingredients in MetaBiotic interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in MetaBiotic interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium animalis subsp. lactis BB-12

Each ingredient & the kinds of drugs it affects

For each ingredient in MetaBiotic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium animalis subsp. lactis BB-121 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium lactis with antibiotic drugs might decrease the effectiveness of B. lactis.
Since B. lactis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. lactis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium animalis subsp. lactis BB-12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MetaBiotic, from the product label.

MetaBiotic

See all MetaBiotic products
Name
Procter & Gamble
City
Cincinnati
State
OH
ZipCode
45202
Phone Number
1-800-983-4237
Pharmacist Counseling Corner

MetaBiotic by MetaBiotic: Common Questions

Does MetaBiotic by MetaBiotic interact with any medications?
Yes. Based on its ingredients, MetaBiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MetaBiotic contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MetaBiotic is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MetaBiotic label
Go deeper

The Full Monographs Behind MetaBiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Animalis Subsp. Lactis

Interacts with 182 drugs

Bifidobacterium animalis subsp. lactis is a well-studied probiotic bacterium commonly added to supplements and yogurts to support digestion and gut health. It appears generally safe for most...

Read the full Bifidobacterium Animalis Subsp. Lactis monograph →
Sources

Sources & How We Checked

MetaBiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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