Sulfadiazine

Generic name: Pronounced as (sul fa dye' a zeen)
Brand names
  • Microsulfon®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 05/15/2017

Sulfadiazine, a sulfa drug, eliminates bacteria that cause infections, especially urinary tract infections. Antibiotics will not work for colds, flu, or other viral infections.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Sulfadiazine comes as a tablet to take by mouth. It is usually taken three to six times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sulfadiazine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

The tablets should be taken with a full glass of water.

Continue to take sulfadiazine even if you feel well. Do not stop taking sulfadiazine without talking to your doctor.

Before taking sulfadiazine,

  • tell your doctor and pharmacist if you are allergic to sulfadiazine, any other sulfa drugs, diuretic ('water pills'), oral diabetes medications, or any other drugs.

  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticoagulants ('blood thinners') such as warfarin (Coumadin), diabetes medications, diuretics ('water pills'), and vitamins.

  • tell your doctor if you have or have ever had liver or kidney disease, asthma, severe allergies, or glucose-6-phosphate dehydrogenase (G-6PD) deficiency (an inherited blood disease).

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking sulfadiazine, call your doctor.

  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Sulfadiazine may make your skin sensitive to sunlight.

You should drink plenty of fluids and take sulfadiazine on an empty stomach.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Sulfadiazine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • diarrhea

    • upset stomach

    • loss of appetite

    • dizziness

  • If you experience any of the following symptoms, call your doctor immediately:

    • rash or skin changes

    • sore throat

    • fever

    • headache

    • joint or muscle aches

    • yellowing of the skin or eyes

    • swelling of the lips or tongue

    • swallowing problems

    • tiredness

    • weakness

    • blood in urine

    • difficulty breathing

    • unusual bleeding or bruising

    • ringing in ears

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Do not let anyone else take your medication. Your prescription is probably not refillable.

If you still have symptoms of an infection after you finish sulfadiazine, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Moxifloxacin.
Repaglinide Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Sulfadiazine.
Montelukast Montelukast The metabolism of Sulfadiazine can be decreased when combined with Montelukast.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be increased when used in combination with Sulfadiazine.
Leflunomide Leflunomide The metabolism of Leflunomide can be decreased when combined with Sulfadiazine.
Nevirapine Nevirapine The metabolism of Nevirapine can be decreased when combined with Sulfadiazine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Sulfadiazine.
Candesartan Candesartan The metabolism of Sulfadiazine can be decreased when combined with Candesartan.
Cilostazol Cilostazol Sulfadiazine may decrease the excretion rate of Cilostazol which could result in a higher serum level.
Clopidogrel Clopidogrel The metabolism of Sulfadiazine can be decreased when combined with Clopidogrel.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Fenofibrate Fenofibrate Sulfadiazine may decrease the excretion rate of Fenofibrate which could result in a higher serum level.
Guanfacine Guanfacine Sulfadiazine may decrease the excretion rate of Guanfacine which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Sulfadiazine may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
Miglitol Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Sulfadiazine.
Mycophenolate Mycophenolate Sulfadiazine may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may increase the hypoglycemic activities of Sulfadiazine.
Paregoric Paregoric The metabolism of Sulfadiazine can be decreased when combined with Morphine.
Penbutolol Penbutolol The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Acebutolol.
Potassium Potassium Potassium may increase the excretion rate of Sulfadiazine which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone The risk or severity of hyperglycemia can be increased when Prednisone is combined with Sulfadiazine.
Ranitidine Ranitidine Sulfadiazine may decrease the excretion rate of Ranitidine which could result in a higher serum level.
Reserpine Reserpine Reserpine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Rizatriptan Rizatriptan Sulfadiazine may decrease the excretion rate of Rizatriptan which could result in a higher serum level.
Sumatriptan Sumatriptan The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Sumatriptan.
Tacrolimus Tacrolimus Tacrolimus may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Triamcinolone Triamcinolone The risk or severity of hyperglycemia can be increased when Triamcinolone is combined with Sulfadiazine.
Ampicillin Injection Ampicillin Injection Sulfadiazine may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection Doxycycline may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Fluconazole Injection Fluconazole Injection The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Fluconazole.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Sulfadiazine.
Levofloxacin Injection Levofloxacin Injection The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Levofloxacin.
Meperidine Injection Meperidine Injection Sulfadiazine may decrease the excretion rate of Meperidine which could result in a higher serum level.
Methylprednisolone Injection Methylprednisolone Injection The risk or severity of hyperglycemia can be increased when Methylprednisolone is combined with Sulfadiazine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Sulfadiazine can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The metabolism of Sulfadiazine can be decreased when combined with Morphine.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Sulfadiazine may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Sulfadiazine.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cyclosporine Cyclosporine The risk or severity of renal failure can be increased when Sulfadiazine is combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Sulfadiazine.
Torsemide Torsemide The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Torasemide.
Olanzapine Olanzapine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Sulfadiazine.
Hydroxychloroquine Hydroxychloroquine The therapeutic efficacy of Hydroxychloroquine can be increased when used in combination with Sulfadiazine.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Sevelamer Sevelamer Sevelamer can cause a decrease in the absorption of Sulfadiazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Temozolomide Temozolomide Sulfadiazine may decrease the excretion rate of Temozolomide which could result in a higher serum level.
Zaleplon Zaleplon Sulfadiazine may decrease the excretion rate of Zaleplon which could result in a higher serum level.
Anakinra Anakinra The metabolism of Sulfadiazine can be increased when combined with Anakinra.
Linezolid Linezolid Linezolid may increase the hypoglycemic activities of Sulfadiazine.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Sulfadiazine.
Etanercept Injection Etanercept Injection The metabolism of Sulfadiazine can be increased when combined with Etanercept.
Perindopril Perindopril Sulfadiazine may decrease the excretion rate of Perindopril which could result in a higher serum level.
Tenofovir Tenofovir Tenofovir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Sirolimus Sirolimus The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Sirolimus.
Epinephrine Injection Epinephrine Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Epinephrine.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Sulfadiazine which could result in a lower serum level and potentially a reduction in efficacy.
Escitalopram Escitalopram The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Escitalopram.
Zonisamide Zonisamide The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Sulfadiazine can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Aripiprazole.
Atomoxetine Atomoxetine Atomoxetine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Sulfadiazine.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Sulfadiazine.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Sulfadiazine.
Rosuvastatin Rosuvastatin The therapeutic efficacy of Rosuvastatin can be increased when used in combination with Sulfadiazine.
Emtricitabine Emtricitabine Sulfadiazine may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
Memantine Memantine Sulfadiazine may decrease the excretion rate of Memantine which could result in a higher serum level.
Tegaserod Tegaserod The metabolism of Sulfadiazine can be decreased when combined with Tegaserod.
Tadalafil Tadalafil Sulfadiazine may decrease the excretion rate of Tadalafil which could result in a higher serum level.
Fosamprenavir Fosamprenavir The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Fosamprenavir.
Gemifloxacin Gemifloxacin The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Gemifloxacin.
Progesterone Progesterone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Sulfadiazine.
Infliximab Injection Infliximab Injection The metabolism of Sulfadiazine can be increased when combined with Infliximab.
Oxandrolone Oxandrolone Oxandrolone may increase the hypoglycemic activities of Sulfadiazine.
Protriptyline Protriptyline Protriptyline may decrease the hypoglycemic activities of Sulfadiazine.
Rifaximin Rifaximin The metabolism of Sulfadiazine can be increased when combined with Rifaximin.
Duloxetine Duloxetine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Duloxetine.
Norethindrone Norethindrone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Norethisterone.
Tinidazole Tinidazole Sulfadiazine may decrease the excretion rate of Tinidazole which could result in a higher serum level.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Sulfadiazine.
Cefditoren Cefditoren Sulfadiazine may decrease the excretion rate of Cefdinir which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Sulfadiazine can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Sulfadiazine.
Ganciclovir Ganciclovir Sulfadiazine may decrease the excretion rate of Ganciclovir which could result in a higher serum level.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be increased when used in combination with Sulfadiazine.
Ribavirin Ribavirin Sulfadiazine may decrease the excretion rate of Ribavirin which could result in a higher serum level.
Valganciclovir Valganciclovir Sulfadiazine may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
Voriconazole Voriconazole The metabolism of Voriconazole can be decreased when combined with Sulfadiazine.
Adefovir Adefovir Adefovir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Pramlintide Injection Pramlintide Injection The therapeutic efficacy of Pramlintide can be increased when used in combination with Sulfadiazine.
Exenatide Injection Exenatide Injection The therapeutic efficacy of Exenatide can be increased when used in combination with Sulfadiazine.
Isocarboxazid Isocarboxazid Isocarboxazid may increase the hypoglycemic activities of Sulfadiazine.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Sulfadiazine.
Fentanyl Fentanyl Sulfadiazine may decrease the excretion rate of Fentanyl which could result in a higher serum level.
Pregabalin Pregabalin The risk or severity of hypoglycemia can be increased when Pregabalin is combined with Sulfadiazine.
Deferasirox Deferasirox The metabolism of Sulfadiazine can be decreased when combined with Deferasirox.
Tipranavir Tipranavir The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Tipranavir.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be increased when used in combination with Sulfadiazine.
Ranolazine Ranolazine Ranolazine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Abatacept Injection Abatacept Injection The metabolism of Sulfadiazine can be increased when combined with Abatacept.
Rasagiline Rasagiline Sulfadiazine may decrease the excretion rate of Rasagiline which could result in a higher serum level.
Imatinib Imatinib The metabolism of Imatinib can be decreased when combined with Sulfadiazine.
Sitagliptin Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Sulfadiazine.
Varenicline Varenicline Sulfadiazine may decrease the excretion rate of Varenicline which could result in a higher serum level.
Albuterol Albuterol Sulfadiazine may decrease the excretion rate of Salbutamol which could result in a higher serum level.
Paliperidone Paliperidone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Paliperidone.
Bortezomib Bortezomib The metabolism of Bortezomib can be decreased when combined with Sulfadiazine.
Clofarabine Injection Clofarabine Injection Sulfadiazine may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Sulfadiazine.
Lubiprostone Lubiprostone Sulfadiazine may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
Primaquine Primaquine The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Primaquine.
Bismuth Subsalicylate Bismuth Subsalicylate Bismuth subsalicylate may increase the hypoglycemic activities of Sulfadiazine.
Darunavir Darunavir The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Darunavir.
Pemetrexed Injection Pemetrexed Injection Sulfadiazine may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Nabilone Nabilone The metabolism of Sulfadiazine can be decreased when combined with Nabilone.
Vorinostat Vorinostat The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Vorinostat.
Sorafenib Sorafenib The metabolism of Sulfadiazine can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Sulfadiazine.
Dronabinol Dronabinol The metabolism of Dronabinol can be decreased when combined with Sulfadiazine.
Lapatinib Lapatinib The metabolism of Sulfadiazine can be decreased when combined with Lapatinib.
Levocetirizine Levocetirizine Sulfadiazine may decrease the excretion rate of Levocetirizine which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Sulfadiazine may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
Azacitidine Injection Azacitidine Injection Sulfadiazine may decrease the excretion rate of Azacitidine which could result in a higher serum level.
Temsirolimus Temsirolimus The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Temsirolimus.
Antipyrine-Benzocaine Otic Antipyrine-Benzocaine Otic The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Benzocaine.
Lenalidomide Lenalidomide Sulfadiazine may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Sulfadiazine can be increased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Sulfadiazine can be decreased when combined with Bexarotene.
Budesonide Budesonide The risk or severity of hyperglycemia can be increased when Budesonide is combined with Sulfadiazine.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Doripenem Injection Doripenem Injection Sulfadiazine may decrease the excretion rate of Doripenem which could result in a higher serum level.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Sulfadiazine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Nebivolol Nebivolol The therapeutic efficacy of Nebivolol can be increased when used in combination with Sulfadiazine.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Sulfadiazine.
Certolizumab Injection Certolizumab Injection The metabolism of Sulfadiazine can be increased when combined with Certolizumab pegol.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Methylnaltrexone Injection Methylnaltrexone Injection Sulfadiazine may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
Midazolam Midazolam Sulfadiazine may decrease the excretion rate of Midazolam which could result in a higher serum level.
Dexrazoxane Injection Dexrazoxane Injection Sulfadiazine may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
Eltrombopag Eltrombopag The metabolism of Sulfadiazine can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Milnacipran.
Plerixafor Injection Plerixafor Injection Sulfadiazine may decrease the excretion rate of Plerixafor which could result in a higher serum level.
Fesoterodine Fesoterodine Sulfadiazine may decrease the excretion rate of Fesoterodine which could result in a higher serum level.
Betaxolol Betaxolol The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Betaxolol.
Iloperidone Iloperidone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Iloperidone.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Sulfadiazine.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Sulfadiazine.
Everolimus Everolimus The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Everolimus.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Sulfadiazine which could result in a lower serum level and potentially a reduction in efficacy.
Pralatrexate Injection Pralatrexate Injection Sulfadiazine may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Sulfadiazine may decrease the excretion rate of Palonosetron which could result in a higher serum level.
Saxagliptin Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Sulfadiazine.
Telavancin Injection Telavancin Injection Sulfadiazine may decrease the excretion rate of Telavancin which could result in a higher serum level.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Sulfadiazine.
Topotecan Topotecan Sulfadiazine may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Sulfadiazine can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Pazopanib can be decreased when combined with Sulfadiazine.
Asenapine Asenapine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Asenapine.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Sulfadiazine.
Levonorgestrel Levonorgestrel The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Levonorgestrel.
Liraglutide Injection Liraglutide Injection The therapeutic efficacy of Liraglutide can be increased when used in combination with Sulfadiazine.
Tocilizumab Injection Tocilizumab Injection The metabolism of Sulfadiazine can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Sulfadiazine may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Sulfadiazine.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Lurasidone Lurasidone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The risk or severity of methemoglobinemia can be increased when Acetaminophen is combined with Sulfadiazine.
Ipilimumab Injection Ipilimumab Injection Sulfadiazine may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Terbutaline Injection Terbutaline Injection Sulfadiazine may decrease the excretion rate of Terbutaline which could result in a higher serum level.
Roflumilast Roflumilast Sulfadiazine may decrease the excretion rate of Roflumilast which could result in a higher serum level.
Linagliptin Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Sulfadiazine.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Sulfadiazine.
Abiraterone Abiraterone The metabolism of Sulfadiazine can be decreased when combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Triptorelin.
Rivaroxaban Rivaroxaban Sulfadiazine may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ruxolitinib Ruxolitinib Sulfadiazine may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
Clobazam Clobazam Clobazam may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Vemurafenib Vemurafenib The metabolism of Sulfadiazine can be decreased when combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Sulfadiazine can be decreased when combined with Vismodegib.
Deferiprone Deferiprone Sulfadiazine may decrease the excretion rate of Deferiprone which could result in a higher serum level.
Naloxone Injection Naloxone Injection Sulfadiazine may decrease the excretion rate of Naloxone which could result in a higher serum level.
Fondaparinux Injection Fondaparinux Injection Sulfadiazine may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
Enzalutamide Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Sulfadiazine.
Mirabegron Mirabegron Sulfadiazine may decrease the excretion rate of Mirabegron which could result in a higher serum level.
Regorafenib Regorafenib The metabolism of Sulfadiazine can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Sulfadiazine can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The risk or severity of hyperglycemia can be increased when Corticotropin is combined with Sulfadiazine.
Teriflunomide Teriflunomide The metabolism of Sulfadiazine can be decreased when combined with Teriflunomide.
Lorcaserin Lorcaserin The therapeutic efficacy of Mecasermin can be increased when used in combination with Sulfadiazine.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Sulfadiazine.
Teduglutide Injection Teduglutide Injection Sulfadiazine may decrease the excretion rate of Teduglutide which could result in a higher serum level.
Alogliptin Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfadiazine.
Ponatinib Ponatinib The metabolism of Sulfadiazine can be decreased when combined with Ponatinib.
Pomalidomide Pomalidomide Sulfadiazine may decrease the excretion rate of Pomalidomide which could result in a higher serum level.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Sulfadiazine.
Canagliflozin Canagliflozin Canagliflozin may increase the hypoglycemic activities of Sulfadiazine.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Sulfadiazine which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The metabolism of Sulfadiazine can be decreased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Sulfadiazine.
Trametinib Trametinib The metabolism of Sulfadiazine can be decreased when combined with Trametinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Sulfadiazine.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Sulfadiazine.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Simeprevir Simeprevir The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Simeprevir.
Sofosbuvir Sofosbuvir Sulfadiazine may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Sulfadiazine.
Apremilast Apremilast The metabolism of Sulfadiazine can be increased when combined with Apremilast.
Droxidopa Droxidopa Sulfadiazine may decrease the excretion rate of Droxidopa which could result in a higher serum level.
Ceritinib Ceritinib The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Sulfadiazine can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfadiazine.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be decreased when combined with Sulfadiazine.
Empagliflozin Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Sulfadiazine.
Dulaglutide Injection Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be increased when used in combination with Sulfadiazine.
Edoxaban Edoxaban Sulfadiazine may decrease the excretion rate of Edoxaban which could result in a higher serum level.
Methamphetamine Methamphetamine Sulfadiazine may decrease the excretion rate of Metamfetamine which could result in a higher serum level.
Tasimelteon Tasimelteon Sulfadiazine may decrease the excretion rate of Tasimelteon which could result in a higher serum level.
Riociguat Riociguat The metabolism of Riociguat can be decreased when combined with Sulfadiazine.
Lanreotide Injection Lanreotide Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Lanreotide.
Secukinumab Injection Secukinumab Injection The metabolism of Sulfadiazine can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Risperidone.
Insulin Human Inhalation Insulin Human Inhalation The therapeutic efficacy of Insulin human can be increased when used in combination with Sulfadiazine.
Lenvatinib Lenvatinib The metabolism of Sulfadiazine can be decreased when combined with Lenvatinib.
Haloperidol Injection Haloperidol Injection The serum concentration of Sulfadiazine can be increased when it is combined with Haloperidol.
Amiloride Amiloride Amiloride may increase the excretion rate of Sulfadiazine which could result in a lower serum level and potentially a reduction in efficacy.
Macitentan Macitentan Sulfadiazine may decrease the excretion rate of Macitentan which could result in a higher serum level.
Prednisolone Prednisolone The risk or severity of hyperglycemia can be increased when Prednisolone is combined with Sulfadiazine.
Brexpiprazole Brexpiprazole The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Ziprasidone.
Penicillin G Procaine Injection Penicillin G Procaine Injection Sulfadiazine may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be increased when used in combination with Sulfadiazine.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Sulfadiazine.
Ixazomib Ixazomib Sulfadiazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rifapentine Rifapentine The metabolism of Sulfadiazine can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Sulfadiazine.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Dexamethasone Injection Dexamethasone Injection The risk or severity of hyperglycemia can be increased when Dexamethasone is combined with Sulfadiazine.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Sulfadiazine.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Sulfadiazine.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Sulfadiazine.
Furosemide Injection Furosemide Injection The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Furosemide.
Rucaparib Rucaparib The metabolism of Sulfadiazine can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be increased when used in combination with Sulfadiazine.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Sulfadiazine.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Sulfadiazine.
Deutetrabenazine Deutetrabenazine Sulfadiazine may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Sulfadiazine may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The risk or severity of hyperglycemia can be increased when Deflazacort is combined with Sulfadiazine.
Safinamide Safinamide Safinamide may increase the hypoglycemic activities of Sulfadiazine.
Naldemedine Naldemedine Sulfadiazine may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Midostaurin Midostaurin The metabolism of Sulfadiazine can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Sulfadiazine can be decreased when combined with Enasidenib.
Benznidazole Benznidazole Sulfadiazine may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Delafloxacin.
Letermovir Letermovir The metabolism of Sulfadiazine can be decreased when combined with Letermovir.
Semaglutide Injection Semaglutide Injection The therapeutic efficacy of Semaglutide can be increased when used in combination with Sulfadiazine.
Ertugliflozin Ertugliflozin The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Sulfadiazine.
Apalutamide Apalutamide The metabolism of Apalutamide can be decreased when combined with Sulfadiazine.
Avatrombopag Avatrombopag The metabolism of Sulfadiazine can be increased when combined with Avatrombopag.
Baricitinib Baricitinib Sulfadiazine may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine Sulfadiazine may decrease the excretion rate of Lofexidine which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Sulfadiazine may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Sulfadiazine.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Sulfadiazine.
Dacomitinib Dacomitinib The metabolism of Dacomitinib can be decreased when combined with Sulfadiazine.
Stiripentol Stiripentol Sulfadiazine may decrease the excretion rate of Stiripentol which could result in a higher serum level.
Glasdegib Glasdegib The metabolism of Glasdegib can be decreased when combined with Sulfadiazine.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Sulfadiazine.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Sulfadiazine.
Rifamycin Rifamycin The metabolism of Sulfadiazine can be decreased when combined with Rifamycin.
Prucalopride Prucalopride Sulfadiazine may decrease the excretion rate of Prucalopride which could result in a higher serum level.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Sulfadiazine can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Sulfadiazine.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Sulfadiazine.
Alpelisib Alpelisib The metabolism of Sulfadiazine can be decreased when combined with Alpelisib.
Solriamfetol Solriamfetol Sulfadiazine may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Sulfadiazine can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Sulfadiazine.
Pitolisant Pitolisant The serum concentration of Sulfadiazine can be decreased when it is combined with Pitolisant.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Sulfadiazine.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Sulfadiazine.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Sulfadiazine.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Sulfadiazine.
Cenobamate Cenobamate The serum concentration of Sulfadiazine can be decreased when it is combined with Cenobamate.
Teprotumumab-trbw Injection Teprotumumab-trbw Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Teprotumumab.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Sulfadiazine.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Sulfadiazine.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Sulfadiazine.
Selpercatinib Selpercatinib The serum concentration of Sulfadiazine can be increased when it is combined with Selpercatinib.
Octreotide Octreotide The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Octreotide.
Pralsetinib Pralsetinib The metabolism of Sulfadiazine can be decreased when combined with Pralsetinib.
Opicapone Opicapone The metabolism of Sulfadiazine can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Sulfadiazine can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Drospirenone.
Viloxazine Viloxazine Sulfadiazine may decrease the excretion rate of Viloxazine which could result in a higher serum level.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Theophylline Theophylline The metabolism of Sulfadiazine can be decreased when combined with Theophylline.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid The metabolism of Sulfadiazine can be decreased when combined with Mefenamic acid.
Naproxen Naproxen Naproxen may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Isotretinoin Isotretinoin Sulfadiazine may decrease the excretion rate of Isotretinoin which could result in a higher serum level.
Sucralfate Sucralfate Sulfadiazine may decrease the excretion rate of Sucralfate which could result in a higher serum level.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Phenobarbital Phenobarbital The metabolism of Sulfadiazine can be decreased when combined with Phenobarbital.
Metaxalone Metaxalone Sulfadiazine may decrease the excretion rate of Metaxalone which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Sulfadiazine is combined with Methotrexate.
Primidone Primidone The metabolism of Primidone can be decreased when combined with Sulfadiazine.
Methsuximide Methsuximide The risk or severity of hypoglycemia can be increased when Methsuximide is combined with Sulfadiazine.
Chlorpromazine Chlorpromazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Chlorpromazine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Sulfadiazine.
Oxazepam Oxazepam Sulfadiazine may decrease the excretion rate of Oxazepam which could result in a higher serum level.
Flurazepam Flurazepam Sulfadiazine may decrease the excretion rate of Flurazepam which could result in a higher serum level.
Clorazepate Clorazepate Sulfadiazine may decrease the excretion rate of Clorazepic acid which could result in a higher serum level.
Lorazepam Lorazepam Lorazepam may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Carmustine Carmustine Carmustine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Amantadine Amantadine Sulfadiazine may decrease the excretion rate of Amantadine which could result in a higher serum level.
Codeine Codeine Codeine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Bromocriptine Bromocriptine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Bromocriptine.
Tranylcypromine Tranylcypromine Tranylcypromine may increase the hypoglycemic activities of Sulfadiazine.
Phenelzine Phenelzine The metabolism of Sulfadiazine can be decreased when combined with Phenelzine.
Procarbazine Procarbazine Procarbazine may increase the hypoglycemic activities of Sulfadiazine.
Tetracycline Tetracycline Sulfadiazine may decrease the excretion rate of Tetracycline which could result in a higher serum level.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Dapsone Dapsone The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Sulfadiazine.
Methadone Methadone The metabolism of Sulfadiazine can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Sulfadiazine can be decreased when combined with Oxybutynin.
Benztropine Benztropine Benzatropine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Colestipol Colestipol Colestipol can cause a decrease in the absorption of Sulfadiazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Maprotiline Maprotiline Sulfadiazine may decrease the excretion rate of Maprotiline which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Azathioprine Azathioprine Sulfadiazine may decrease the excretion rate of Azathioprine which could result in a higher serum level.
Phentermine Phentermine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Phentermine.
Methylphenidate Methylphenidate Sulfadiazine may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
Amoxapine Amoxapine Amoxapine may decrease the hypoglycemic activities of Sulfadiazine.
Sulfasalazine Sulfasalazine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Sulfadiazine.
Hydrocortisone Hydrocortisone The risk or severity of hyperglycemia can be increased when Hydrocortisone is combined with Sulfadiazine.
Phenazopyridine Phenazopyridine The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Phenazopyridine.
Carbamazepine Carbamazepine Carbamazepine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Methyldopa Methyldopa Sulfadiazine may decrease the excretion rate of Methyldopa which could result in a higher serum level.
Hydralazine Hydralazine Sulfadiazine may decrease the excretion rate of Hydralazine which could result in a higher serum level.
Cimetidine Cimetidine Sulfadiazine may decrease the excretion rate of Cimetidine which could result in a higher serum level.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Warfarin Warfarin The metabolism of Sulfadiazine can be decreased when combined with Warfarin.
Clonazepam Clonazepam Sulfadiazine may decrease the excretion rate of Clonazepam which could result in a higher serum level.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Sulfadiazine.
Promethazine Promethazine Sulfadiazine may decrease the excretion rate of Promethazine which could result in a higher serum level.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Nitrofurantoin.
Griseofulvin Griseofulvin The metabolism of Sulfadiazine can be increased when combined with Griseofulvin.
Methenamine Methenamine Methenamine can cause a decrease in the absorption of Sulfadiazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Digoxin Digoxin Sulfadiazine may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Chloroquine.
Quinine Quinine The risk or severity of methemoglobinemia can be increased when Quinine is combined with Sulfadiazine.
Ethosuximide Ethosuximide The risk or severity of hypoglycemia can be increased when Ethosuximide is combined with Sulfadiazine.
Triamterene Triamterene Triamterene may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Lactulose Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Sulfadiazine.
Sulfinpyrazone Sulfinpyrazone The metabolism of Sulfadiazine can be decreased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Chlorothiazide.
Chlorthalidone Chlorthalidone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Chlorthalidone.
Metolazone Metolazone The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Metolazone.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Sulfadiazine which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital The metabolism of Sulfadiazine can be increased when combined with Secobarbital.
Desipramine Desipramine Desipramine may decrease the hypoglycemic activities of Sulfadiazine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Sulfadiazine.
Imipramine Imipramine Imipramine may decrease the hypoglycemic activities of Sulfadiazine.
Probenecid Probenecid The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Probenecid.
Quinidine Quinidine Sulfadiazine may decrease the excretion rate of Quinidine which could result in a higher serum level.
Procainamide Procainamide Sulfadiazine may decrease the excretion rate of Procainamide which could result in a higher serum level.
Isoniazid Isoniazid Sulfadiazine may decrease the excretion rate of Isoniazid which could result in a higher serum level.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Rifampin Rifampin The metabolism of Sulfadiazine can be increased when combined with Rifampicin.
Disopyramide Disopyramide The therapeutic efficacy of Disopyramide can be increased when used in combination with Sulfadiazine.
Valproic Acid Valproic Acid The risk or severity of methemoglobinemia can be increased when Valproic acid is combined with Sulfadiazine.
Tamoxifen Tamoxifen The metabolism of Sulfadiazine can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Levothyroxine Levothyroxine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Levothyroxine.
Liothyronine Liothyronine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Liothyronine.
Methimazole Methimazole Sulfadiazine may decrease the excretion rate of Methimazole which could result in a higher serum level.
Chlorpropamide Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Sulfadiazine.
Tolbutamide Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Sulfadiazine.
Tolazamide Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Sulfadiazine.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Sulfadiazine.
Niacin Niacin The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Niacin.
Baclofen Baclofen The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Baclofen.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Methyclothiazide Methyclothiazide The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Methyclothiazide.
Hydrochlorothiazide Hydrochlorothiazide The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Hydrochlorothiazide.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Danazol Danazol The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Danazol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The therapeutic efficacy of Propranolol can be increased when used in combination with Sulfadiazine.
Pseudoephedrine Pseudoephedrine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Pseudoephedrine.
Nortriptyline Nortriptyline Nortriptyline may decrease the hypoglycemic activities of Sulfadiazine.
Spironolactone Spironolactone The metabolism of Sulfadiazine can be decreased when combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection Amphotericin B may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Phytonadione Phytonadione Sulfadiazine may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Nadolol Nadolol The therapeutic efficacy of Nadolol can be increased when used in combination with Sulfadiazine.
Cholestyramine Resin Cholestyramine Resin Cholestyramine can cause a decrease in the absorption of Sulfadiazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Allopurinol Allopurinol Sulfadiazine may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Fluoxymesterone Fluoxymesterone Fluoxymesterone may increase the hypoglycemic activities of Sulfadiazine.
Flavoxate Flavoxate Sulfadiazine may decrease the excretion rate of Flavoxate which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Sulfadiazine.
Colchicine Colchicine The metabolism of Sulfadiazine can be decreased when combined with Colchicine.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cephalexin Cephalexin Cephalexin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Dacarbazine Dacarbazine Sulfadiazine may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
Acetazolamide Acetazolamide The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Ketoconazole Ketoconazole The metabolism of Sulfadiazine can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Sulfadiazine may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Ethacrynic Acid Ethacrynic Acid The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Etacrynic acid.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Metoprolol Metoprolol The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Metoprolol.
Aspirin Aspirin The risk or severity of hypoglycemia can be increased when Acetylsalicylic acid is combined with Sulfadiazine.
Salsalate Salsalate Salsalate may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Alprazolam Alprazolam Sulfadiazine may decrease the excretion rate of Alprazolam which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Triazolam Triazolam Sulfadiazine may decrease the excretion rate of Triazolam which could result in a higher serum level.
Dicyclomine Dicyclomine Sulfadiazine may decrease the excretion rate of Dicyclomine which could result in a higher serum level.
Propantheline Propantheline Sulfadiazine may decrease the excretion rate of Propantheline which could result in a higher serum level.
Diltiazem Diltiazem The metabolism of Sulfadiazine can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Sulfadiazine can be decreased when combined with Nifedipine.
Timolol Timolol The therapeutic efficacy of Timolol can be increased when used in combination with Sulfadiazine.
Verapamil Verapamil The metabolism of Sulfadiazine can be decreased when combined with Verapamil.
Atenolol Atenolol The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Atenolol.
Pindolol Pindolol The therapeutic efficacy of Pindolol can be increased when used in combination with Sulfadiazine.
Cisplatin Injection Cisplatin Injection Sulfadiazine may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may increase the hypoglycemic activities of Sulfadiazine.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Bumetanide Bumetanide The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Bumetanide.
Glyburide Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Sulfadiazine.
Glipizide Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Sulfadiazine.
Indapamide Indapamide The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Indapamide.
Amoxicillin Amoxicillin Sulfadiazine may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
Oxacillin Injection Oxacillin Injection Sulfadiazine may decrease the excretion rate of Oxacillin which could result in a higher serum level.
Pentoxifylline Pentoxifylline Sulfadiazine may decrease the excretion rate of Pentoxifylline which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection The therapeutic efficacy of Pentamidine can be increased when used in combination with Sulfadiazine.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Labetalol Labetalol The therapeutic efficacy of Labetalol can be increased when used in combination with Sulfadiazine.
Auranofin Auranofin Sulfadiazine may decrease the excretion rate of Auranofin which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Leuprolide.
Gemfibrozil Gemfibrozil The metabolism of Sulfadiazine can be decreased when combined with Gemfibrozil.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Ketoprofen Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Sulfadiazine.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Sulfadiazine.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Buspirone Buspirone Sulfadiazine may decrease the excretion rate of Buspirone which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Sulfadiazine can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may increase the hypoglycemic activities of Sulfadiazine.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Sulfadiazine.
Nimodipine Nimodipine The risk or severity of hypoglycemia can be increased when Nimodipine is combined with Sulfadiazine.
Clozapine Clozapine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Clozapine.
Estazolam Estazolam Sulfadiazine may decrease the excretion rate of Estazolam which could result in a higher serum level.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Sulfadiazine.
Ofloxacin Ofloxacin The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Ofloxacin.
Didanosine Didanosine Sulfadiazine may decrease the excretion rate of Didanosine which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Sulfadiazine may decrease the excretion rate of Pentostatin which could result in a higher serum level.
Benazepril Benazepril The risk or severity of hypoglycemia can be increased when Benazepril is combined with Sulfadiazine.
Etodolac Etodolac Etodolac may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Felodipine Felodipine The metabolism of Sulfadiazine can be decreased when combined with Felodipine.
Fosinopril Fosinopril Sulfadiazine may decrease the excretion rate of Fosinopril which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Simvastatin Simvastatin The metabolism of Sulfadiazine can be decreased when combined with Simvastatin.
Amlodipine Amlodipine The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Sulfadiazine.
Lisinopril Lisinopril Sulfadiazine may decrease the excretion rate of Lisinopril which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Rifabutin Rifabutin The metabolism of Sulfadiazine can be increased when combined with Rifabutin.
Sotalol Sotalol The risk or severity of hypoglycemia can be increased when Sotalol is combined with Sulfadiazine.
Bisoprolol Bisoprolol The therapeutic efficacy of Bisoprolol can be increased when used in combination with Sulfadiazine.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Sulfadiazine.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Sulfadiazine.
Isradipine Isradipine The risk or severity of hypoglycemia can be increased when Isradipine is combined with Sulfadiazine.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Sulfadiazine.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Sulfadiazine.
Fluvastatin Fluvastatin The metabolism of Sulfadiazine can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The risk or severity of hypoglycemia can be increased when Venlafaxine is combined with Sulfadiazine.
Fluvoxamine Fluvoxamine The risk or severity of hypoglycemia can be increased when Fluvoxamine is combined with Sulfadiazine.
Nefazodone Nefazodone The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Lamotrigine.
Losartan Losartan The metabolism of Sulfadiazine can be decreased when combined with Losartan.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Tramadol Tramadol Tramadol may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Lansoprazole Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Sulfadiazine.
Ifosfamide Injection Ifosfamide Injection The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Ifosfamide.
Nicardipine Nicardipine The metabolism of Sulfadiazine can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Sulfadiazine.
Ticlopidine Ticlopidine Ticlopidine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Saquinavir Saquinavir The metabolism of Sulfadiazine can be decreased when combined with Saquinavir.
Metformin Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Sulfadiazine.
Nisoldipine Nisoldipine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Nisoldipine.
Lamivudine Lamivudine Sulfadiazine may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Acarbose Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfadiazine.
Glimepiride Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Sulfadiazine.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Sulfadiazine.
Gemcitabine Injection Gemcitabine Injection Sulfadiazine may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
Indinavir Indinavir The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Indinavir.
Ritonavir Ritonavir The serum concentration of Sulfadiazine can be increased when it is combined with Ritonavir.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Meropenem Injection Meropenem Injection Sulfadiazine may decrease the excretion rate of Meropenem which could result in a higher serum level.
Clomipramine Clomipramine Clomipramine may decrease the hypoglycemic activities of Sulfadiazine.
Zafirlukast Zafirlukast The metabolism of Sulfadiazine can be decreased when combined with Zafirlukast.
Fosfomycin Fosfomycin Sulfadiazine may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
Topiramate Topiramate Topiramate may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Sulfadiazine.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Sulfadiazine.
Insulin Lispro Injection Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be increased when used in combination with Sulfadiazine.
Pramipexole Pramipexole Sulfadiazine may decrease the excretion rate of Pramipexole which could result in a higher serum level.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Sulfadiazine.
Nelfinavir Nelfinavir The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Nelfinavir.
Loratadine Loratadine The metabolism of Sulfadiazine can be decreased when combined with Loratadine.
Carvedilol Carvedilol The therapeutic efficacy of Carvedilol can be increased when used in combination with Sulfadiazine.
Nilutamide Nilutamide The metabolism of Sulfadiazine can be decreased when combined with Nilutamide.
Flutamide Flutamide The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Flutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Sulfadiazine.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Sulfadiazine.
Propafenone Propafenone The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Propafenone.
Raloxifene Raloxifene The metabolism of Sulfadiazine can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Sulfadiazine can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The therapeutic efficacy of Tamsulosin can be increased when used in combination with Sulfadiazine.
Quetiapine Quetiapine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Quetiapine.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Cetirizine Cetirizine Cetirizine may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Paroxetine Paroxetine The risk or severity of hypoglycemia can be increased when Sulfadiazine is combined with Paroxetine.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Citalopram Citalopram The risk or severity of hypoglycemia can be increased when Citalopram is combined with Sulfadiazine.
Capecitabine Capecitabine The metabolism of Capecitabine can be decreased when combined with Sulfadiazine.
Efavirenz Efavirenz The metabolism of Sulfadiazine can be decreased when combined with Efavirenz.
Abacavir Abacavir Sulfadiazine may decrease the excretion rate of Abacavir which could result in a higher serum level.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Sulfadiazine.
Pioglitazone Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Sulfadiazine.
Celecoxib Celecoxib The risk or severity of methemoglobinemia can be increased when Celecoxib is combined with Sulfadiazine.
Rosiglitazone Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Sulfadiazine.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Sulfadiazine.
Thalidomide Thalidomide The metabolism of Thalidomide can be decreased when combined with Sulfadiazine.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Sulfadiazine which could result in a higher serum level.
Colesevelam Colesevelam Colesevelam can cause a decrease in the absorption of Sulfadiazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Balsalazide Balsalazide Balsalazide may increase the hypoglycemic activities of Sulfadiazine.
Nateglinide Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Sulfadiazine.
Rabeprazole Rabeprazole The metabolism of Sulfadiazine can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Sulfadiazine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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