Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

MindHealth Cherry Lime Flavor Ingredients & Drug Interactions

by Arbonne

MindHealth Cherry Lime Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MindHealth Cherry Lime Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

MindHealth Cherry Lime Flavor is a dietary supplement by Arbonne with 4 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 1,170 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Grape seed extract, Phosphatidylserine, Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against MindHealth Cherry Lime Flavor by Arbonne

Ask about any prescription or over-the-counter medication and we check it for interactions with MindHealth Cherry Lime Flavor by Arbonne — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of MindHealth Cherry Lime Flavor by Arbonne

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

MindHealth Cherry Lime Flavor is a powder with 4 active ingredients. Vitamin B12 supports energy and nerve health, coenzyme Q10 is an antioxidant that may support heart and cellular function, grape seed extract provides polyphenols, and phosphatidylserine is a compound that supports brain health and cognitive function.

The product also contains inactive ingredients — fillers, binders, and flavorings such as cane sugar, citric acid, stevia leaf extract, and gum arabic — to hold the powder together and improve taste.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Imerslund-Grasbeck disease — rated "Effective" (Vitamin B12) (Natural Medicines).
  • On file: Vitamin B12 deficiency — rated "Effective" (Vitamin B12) (Natural Medicines).
  • On file: Coenzyme Q10 deficiency — rated "Likely Effective" (Coenzyme Q10) (Natural Medicines).
  • On file: Cyanide poisoning — rated "Likely Effective" (Vitamin B12) (Natural Medicines).
  • On file: Age-related cognitive decline — rated "Possibly Effective" (Phosphatidylserine) (Natural Medicines).

Vitamin B12 is effective for treating B12 deficiency and a rare genetic condition called Imerslund-Grasbeck disease, and likely effective for cyanide poisoning. It is possibly effective for canker sores and nerve pain after shingles (postherpetic neuralgia).

Coenzyme Q10 is likely effective for CoQ10 deficiency and possibly effective for fibromyalgia, migraines, congestive heart failure, and diabetic nerve pain. Grape seed extract is possibly effective for chronic venous insufficiency (swelling in the legs and feet from poor circulation) but possibly ineffective for chemotherapy-related nausea, hay fever, and weight loss.

Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease; evidence is insufficient to rate it for ADHD, athletic performance, cognitive function, or dementia.

The evidence, ingredient by ingredient Vitamin B12 Coenzyme Q10 Grape Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B12 is generally very safe and is needed and considered safe during pregnancy and breastfeeding at recommended amounts. Coenzyme Q10 is generally well tolerated, though gastrointestinal side effects such as nausea, diarrhea, and heartburn occur in less than 1% of users; safety in pregnancy is not well established and you should avoid it unless your doctor advises otherwise, and safety while breastfeeding has not been well studied.

Grape seed extract is generally well tolerated and likely safe during pregnancy and breastfeeding, though concentrated supplements should be avoided in pregnancy due to limited data. Phosphatidylserine is generally well tolerated in studies but long-term safety is not fully established; it is not recommended during pregnancy or breastfeeding due to insufficient safety information.

Common side effects across ingredients include gastrointestinal upset, headache, nausea, and insomnia.

Side effects, ingredient by ingredient Vitamin B12 Coenzyme Q10 Grape Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Grape, Vitamin B12, Coenzyme Q10, Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 1,171 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take anticoagulant or antiplatelet drugs (like warfarin or aspirin) — grape seed extract may increase bleeding risk. Moderate caution applies to metformin, antihypertensive drugs, cyclosporine, midazolam, and any medications processed by your liver's cytochrome P450 system (CYP1A2, CYP2D6, CYP2E1, or CYP3A4).

Also check if you take anticholinergic or cholinergic drugs, which phosphatidylserine may affect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with vitamin B12 deficiency, heart and brain health, or circulation issues — but it interacts with a substantial number of medications. If you take metformin, warfarin, blood pressure drugs, cyclosporine, midazolam, or anticholinergic or cholinergic medications, check with your doctor or pharmacist before starting.

Pregnant or breastfeeding individuals should also discuss this product with their own healthcare provider before use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MindHealth Cherry Lime Flavor, straight from the product label.

Brand Arbonne
Net contents 30 Stick Pack(s); 3.6 Ounce(s); 102 Gram(s)
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 285615
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MindHealth Cherry Lime Flavor by Arbonne, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.4 Gram(s)
Maximum serving Sizes:
3.4 Gram(s)
Servings per container
30
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Vitamin B122.5 mcg104%
Added Sugars2 Gram(s)4%
Total Sugars2 Gram(s)--
Coenzyme Q1050 mg--
Grape seed extract150 mg--
Phosphatidylserine100 mg--

Other ingredients: Cane Sugar, Citric Acid, Natural flavors, Malic Acid, Stevia leaf extract, Silicon Dioxide, Gum Arabic, Beet juice concentrate, Dicalcium Phosphate, Mixed Tocopherols, Ascorbic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Note: Pregnant or breastfeeding women, those with a medical condition, and those taking medication should consult with a healthcare professional before use.

Do not use if outer seal is broken or missing or if packet is torn or open.

Keep out of reach of children.

Do not exceed the recommended daily intake of 1 stick pack per day.

Formulation

Manufactured in USA from imported materials.

Vegan

Certified Gluten-Free GFCO.org Non GMO project Verified Nongmoproject.org

100% Vegan - gluten free

100% Vegan - gluten free

Focus super powder

Helps support cognitive function

Storage

Keep in a cool, dry place.

Seals/Symbols

Certified B Corporation A force for good for people and planet. Vegan Certified Gluten-Free GFCO.org OU (Kosher) Non GMO project Verified Nongmoproject.org IFANCA Certified crescent M Halal

Formula

OU (Kosher)

IFANCA Certified crescent M Halal

With sunflower phosphatidylserine

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General Statements

30 stick packs - 0.12 oz / 3.4 g each

Brand IP Statement(s)

Arbonne Mind. Body. Skin.

Suggested/Recommended/Usage/Directions

Directions: Add 1 stick pack to 4 fl. oz. of water.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MindHealth Cherry Lime Flavor by Arbonne label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MindHealth Cherry Lime Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MindHealth Cherry Lime Flavor by Arbonne

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3.4 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
2.5 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
50 mg per serving

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

Grape seed extract

Interacts with
910 drugs
150 mg per serving Form: Polyphenols

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and b...

Grape seed extract monograph & interactions

Phosphatidylserine

Interacts with
219 drugs
100 mg per serving Form: Sunflower Phospholipids

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Phosphatidylserine monograph & interactions

Other (inactive) ingredients: Cane Sugar, Citric Acid, Natural flavors, Malic Acid, Stevia leaf extract, Silicon Dioxide, Gum Arabic, Beet juice concentrate, Dicalcium Phosphate, Mixed Tocopherols, Ascorbic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

MindHealth Cherry Lime Flavor by Arbonne Drug Interactions

Want to check YOUR meds against MindHealth Cherry Lime Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,170Drugs
998 Moderate 172 Minor

Ingredients driving the most interactions

Grape seed extract 910
Phosphatidylserine 219
Coenzyme Q10 198
Vitamin B12 20

Individual Drug Interactions

The ingredients in MindHealth Cherry Lime Flavor interact with 1,170 drugs. Click any drug to see the details.

4 of the 4 ingredients in MindHealth Cherry Lime Flavor interact with drugs. Each result below shows which ingredient is responsible. Grape seed extract Phosphatidylserine Coenzyme Q10 Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in MindHealth Cherry Lime Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Grape seed extract9 drug types · 910 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.

Likelihood Possible Evidence D
Phenacetin

Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.

Likelihood Unlikely Evidence D
Grape seed extract full monograph & interactions

Phosphatidylserine2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Phosphatidylserine full monograph & interactions

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MindHealth Cherry Lime Flavor, from the product label.

Arbonne

See all Arbonne products
Name
Arbonne International, LLC
Street Address
9400 Jeronimo Road
City
Irvine
State
CA
ZipCode
92618
Phone Number
1.800.272.6663
Web Address
arbonne.com
Pharmacist Counseling Corner

MindHealth Cherry Lime Flavor by Arbonne: Common Questions

Does MindHealth Cherry Lime Flavor by Arbonne interact with any medications?
Yes. Based on its ingredients, MindHealth Cherry Lime Flavor has a known interaction with 1,170 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MindHealth Cherry Lime Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or nursing?
Vitamin B12 is safe and needed during pregnancy and breastfeeding. Grape seed extract is likely safe during pregnancy and breastfeeding. However, coenzyme Q10 safety is not well established in pregnancy and breastfeeding safety has not been well studied. Phosphatidylserine is not recommended during either pregnancy or breastfeeding due to insufficient safety data. Talk with your doctor or pharmacist about whether this product is right for you.
What are the most common side effects?
Gastrointestinal upset — nausea, diarrhea, heartburn, abdominal pain — is the most common side effect, occurring in less than 1% of users in studies. Headache and insomnia have also been reported. These effects are generally mild and often improve if you divide larger daily doses or take the product with food.
Will this help with memory and brain fog?
Phosphatidylserine in this product is possibly effective for age-related cognitive decline and Alzheimer disease. Vitamin B12 is essential for nerve and brain health and is effective for B12 deficiency, which can affect cognition. However, evidence is insufficient to confirm this product works for general memory or brain fog — talk with your doctor about whether it's right for your situation.
Can I take this long-term?
Vitamin B12 is very safe long-term with no established upper limit. Coenzyme Q10 and grape seed extract are generally well tolerated over time in studies. Phosphatidylserine is generally well tolerated, but long-term safety is not fully established, so check with your doctor if you plan to use it beyond a few months.
What is phosphatidylserine and why is it in here?
Phosphatidylserine is a naturally occurring compound found in cell membranes that is possibly effective for age-related cognitive decline and Alzheimer disease. It is thought to support brain cell structure and function, which is why it's included in a product aimed at mental health.
If I take cyclosporine (an immunosuppressant), can I take this product?
Grape seed extract in this product may decrease cyclosporine absorption by up to 30%, reducing its effectiveness. If you take cyclosporine, check with your doctor or pharmacist before starting this product. If approved, separate doses of grape juice or grape seed extract from cyclosporine by at least 2 hours.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MindHealth Cherry Lime Flavor label
Go deeper

The Full Monographs Behind MindHealth Cherry Lime Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

Grape

Interacts with 910 drugs

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...

Read the full Grape monograph → Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

MindHealth Cherry Lime Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 113 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
  15. Omboni, E., Checchini, M., and Longoni, F. [Hypopotassemia and megaloblastic anemia. Presentation of a case]. Minerva Med 8-31-1987;78(16):1255-1257.
  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
  17. Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol 2014;33(2):94-5. PubMed
  18. Carman KB, Belgemen T, Yis U. Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. Pediatr Emerg Care 2013;29(11):1223-4. PubMed
  19. Djuric V, Bogic M, Popadic AP, et al. Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin. Ann Allergy Asthma Immunol 2012;108(3):207-8. PubMed
  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
  21. Patiroglu T, Unal E, Yildirim S. Infantile tremor syndrome associated with cobalamin therapy: A case report. Clin Neurol Neurosurg 2013;115(9):1903-5. PubMed
  22. Schulte S, Barkema LW, Kardaun SH. Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12). J Dtsch Dermatol Ges 2014;12(6):502-3.
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Coenzyme Q10 40 references
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Grape 34 references
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  10. Schaefer, E., Peil, H., Ambrosetti, L., and Petrini, O. Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial. Arzneimittelforschun PubMed
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  16. Etheridge, A. S., Black, S. R., Patel, P. R., So, J., and Mathews, J. M. An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constitu
  17. Krikorian, R., Nash, T. A., Shidler, M. D., Shukitt-Hale, B., and Joseph, J. A. Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr. 2010;103(5):730-734. PubMed
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See these in context on the Grape monograph →

Phosphatidylserine 9 references
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See these in context on the Phosphatidylserine monograph →

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