Mitochondrial Basics With BioPQQ By Life Extension Overview & Drug Interactions
Check For Interactions With Mitochondrial Basics With BioPQQ
Supplement: Mitochondrial Basics With BioPQQ by Life Extension
Mitochondrial Basics With BioPQQ Label Images
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
Calcium
Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium| Ingredient Group | Calcium |
|---|---|
| Category | mineral |
- Calcium Carbonate
Sodium
| Ingredient Group | Sodium |
|---|---|
| Category | mineral |
ArginoCarn Acetyl-L-Carnitine Arginate Dihydrochloride
| Ingredient Group | Acetyl L-Carnitine Arginate |
|---|---|
| Category | non-nutrient/non-botanical |
R-Lipoic Acid
Alpha-lipoic acid (ALA) is a naturally occurring compound that is made by the body and is also found in some foods, such as spinach, broccoli, and potatoes. It plays a role in energy production in the body and acts as an antioxidant, helping to protect cells from damage caused by free radicals. ALA has been studied for its potential health benefits, including the treatment of certain types of nerve damage, diabetes, and liver disease.
See More Information Regarding Alpha-lipoic Acid| Ingredient Group | Alpha Lipoic Acid |
|---|---|
| Category | non-nutrient/non-botanical |
- Na-RALA Sodium R-Lipoate
BioPQQ(R) Pyrroloquinoline quinone disodium salt
| Ingredient Group | Pyrroloquinoline Quinone |
|---|---|
| Category | non-nutrient/non-botanical |
Drugs that interact with Mitochondrial Basics With BioPQQ by Life Extension
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
| Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
|---|---|
| Minimum serving Sizes: |
1 Capsule(s)
|
| Maximum serving Sizes: |
1 Capsule(s)
|
| Servings per container | 30 |
| Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
|---|---|---|---|
| Calcium |
15 mg
|
Calcium |
|
| Sodium |
14 mg
|
Sodium |
|
| ArginoCarn Acetyl-L-Carnitine Arginate Dihydrochloride |
250 mg
|
Acetyl L-Carnitine Arginate |
|
| R-Lipoic Acid |
100 mg
|
Alpha Lipoic Acid |
|
| BioPQQ(R) Pyrroloquinoline quinone disodium salt |
10 mg
|
Pyrroloquinoline Quinone |
|
| Other Ingredients: |
Microcrystalline Cellulose
Vegetable Cellulose
Silica
Calcium Silicate
Vegetable Stearate
Candelilla Wax
Beeswax
|
|---|
Label Statments:
| General Statements |
- Foundation for Longer Life
- Supports optimal mitochondrial biogenesis and function
- With this lower-cost option, all members have access to targeted nutrients required to support mitochondrial function and the generation of healthy new mitochondria.
- Behind every physiological process your body needs to survive and thrive are cellular energy generators known as mitochondria. Their function is so crucial that a growing number of scientists believe mitochondrial longevity may determine overall longevity in aging humans.1-5 One of the most serious events that cause the loss of cellular vitality is the depletion of mitochondrial energy-producing function. Cells require healthy mitochondrial activity to perform life-sustaining metabolic processes. As mitochondrial function weakens in our cells, so does the vitality of organs such as the heart and brain or in some cases, the entire body.6-11
- References
1. Biochimie. 1999 Dec;81(12):1131-2.
2. Lancet. 1989 Mar 25;1(8639):642-5.
3. Curr Opin Clin Nutr Metab Care. 2010 Jul 7.
4. Age (Dordr). 2010 Mar 20.
5. Ageing Res Rev. 2010 Jun 25.
6. Ann N Y Acad Sci. 2004 Jun;1019:406-11.
7. Postepy Biochem. 2008;54(2):129-41.
8. Ann N Y Acad Sci. 2002 Apr;959:491-507.
9. Chang Gung Med J. 2009 Mar-Apr;32(2):113-32.
10. Proc Natl Acad Sci USA. 1997 94:3064-9.
11. Ann NY Acad. Sci. 1998; 854:118-27.
12. J Neurosci Res. 2011 Feb;89(2):222-30.
13. Nature. 2003 Apr 24;422(6934):832.
14. Connect Tissue Res. 1993;29(2):153-61.
15. J Biol Chem. 2010. Jan 1;285:142-152.
16. Alt Med Rev. 2009; 14(3):268-77.
17. Entrez Gene: PARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha [Homo sapiens] GeneID: 10891.
18. Entrez Gene: CREBBP CREB binding protein [Homo sapiens] GeneID: 1387.
19. Bauerly K, Harris C, Chowanadisai W, Graham J, Havel PJ, Tchaparian E, Satre M, Karliner JS, Rucker RB. Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. PLoS One. 2011;6(7):e21779. Epub 2011 Jul 21.
20. Biochem Biophys Res Commun. 1996 Apr 16;221(2):422-9.
21. FASEB J. 1999 Feb;13(2):411-8.
22. Antioxid Redox Signal. 2000 Fall;2(3):473-83.
23. Biochem Mol Biol Int. 1995 Oct;37(2):361-70.
24. Arch Biochem Biophys. 2004 Mar 1;423(1):126-35.
25. Redox Rep. 2005;10(1):52-60.
|
|---|---|
| Formula |
- Pyrroloquinoline Quinone
- Mitochondrial Basics brings together three cutting-edge mitochondrial energizers in a one capsule per day, value-priced formula:
1. PQQ. This breakthrough micronutrient is technically a vitamin12-14 and has recently been shown to trigger mitochondrial biogenesis—the growth of new mitochondria in aging cells!15 PQQ also activates genes involved in protecting the delicate structures within the mitochondria.16-19
2. R-lipoic acid. The effects of free radicals comprise one of the chief obstacles to optimal mitochondrial energy production. Published studies confirm R-lipoic acid's power to promote mitochondrial bioenergetics while simultaneously blunting free radical activity.20-25 Mitochondrial Basics contains the superior Bio-Enhanced(R) R-lipoic acid and is in a proprietary microencapsulated form for better absorption.
3. Acetyl-L-carnitine arginate. Fats are shuttled into the mitochondria for metabolic combustion by the amino acid carnitine. The acetylated form of carnitine helps to facilitate more efficient utilization of fats than carnitine alone.
|
| FDA Statement of Identity |
- Dietary Supplement
|
| Precautions |
- The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging.
- You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.
- Warnings
- Keep out of reach of children
- - Do not exceed recommended use
- Do not purchase if outer seal is broken or damaged.
- - When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
|
| Brand IP Statement(s) |
- BioPQQ(R) is a registered trademark of MGC (Japan).
Bio-Enhanced(R) is a registered trademark of Geronova Research, Inc.
ArginoCarn(R) is a registered trademark of Sigma-tau HealthSciences, Inc. and is protected by US patents 6,365,622, US 6,703,042 and EP1202956.
- All Contents Copyright (C) 1995-2013 Life Extension(R) All rights reserved
|
| Suggested/Recommended/Usage/Directions |
- Dosage and Use
- Take one (1) capsule once or twice daily, preferably early in the day, or as recommended by a healthcare practitioner.
- This product can be taken with or without food.
|
| FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
|
Brand Information
See all products by this brand
| To report a serious adverse event or obtain product information, contact | |
|---|---|
| Phone Number | 1-866-280-2852 |
| Not Present | |
| Name | Life Extension |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.