No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Moducare Ingredients & Drug Interactions

by Nature's Harmony

Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Moducare is a dietary supplement by Nature's Harmony with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Moducare by Nature's Harmony

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Moducare has 2 active ingredients: beta-sitosterol and beta-sitosterolin. Both are plant-derived compounds (phytosterols) that support cholesterol metabolism and prostate health.

The capsules also contain inactive ingredients including rice flour, magnesium stearate, silicon dioxide, cellulose, and vegetable cellulose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-sitosterol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy immune system balance.
  • We looked for evidence on: Allergic rhinitis (hay fever), Asthma, HIV/AIDS, Rheumatoid arthritis (RA), Systemic lupus erythematosus (SLE), Tuberculosis — and 4 related terms.
  • The closest evidence on file: Beta-sitosterol is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Beta-sitosterol is rated "Insufficient Reliable Evidence To Rate" for Asthma, Upper respiratory tract infection (URTI), HIV/AIDS, Rheumatoid arthritis (RA), and more.

Beta-sitosterol and beta-sitosterolin are likely effective for benign prostatic hyperplasia (enlarged prostate). They're possibly effective for familial hypercholesterolemia (inherited high cholesterol) and coronary heart disease when used as part of a heart-healthy regimen.

The strength of the evidence varies by condition, so talk with your doctor about whether this product fits your particular health goals.

The evidence, ingredient by ingredient Beta-sitosterol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated when taken short-term by most adults. The most common side effects are constipation, diarrhea, gas, indigestion, and nausea.

Beta-sitosterol may worsen acne in some people, and there's a rare report of acute pancreatitis in one person who started the supplement (symptoms resolved when he stopped). Appetite reduction has also been reported.

Safety data during pregnancy and breastfeeding is insufficient, so avoid supplemental use in these situations.

Side effects, ingredient by ingredient Beta-sitosterol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, it's always smart to run your full medication list through the checker below or ask your pharmacist before you start any new supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Moducare is a good choice if you're interested in supporting prostate health or managing cholesterol — the evidence backs its use for both. Watch for digestive side effects, especially when you first start.

If you're pregnant, breastfeeding, or have any unusual symptoms like abdominal pain, talk to your pharmacist or doctor before using it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moducare, straight from the product label.

Brand Nature's Harmony
Net contents 105 Vegetable Capsule(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 19943
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moducare by Nature's Harmony, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Beta-sitosterol20 mg--
Beta-sitosterolin0.2 mg--

Other ingredients: Rice Flour, Magnesium Stearate, Silicon Dioxide, Cellulose, Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Adults and children 17 years and over: Take 1 capsule three times daily OR 2 capsules upon arising and 1 capsule before bed. Children 11 to 16 years: Take 1 capsule, twice daily. Children 5 to 10 years: Take 1 capsule, one to two times daily. For best results, take with water or juice between meals on an empty stomach. Use for a minimum of two to three months to see a beneficial effect.

Precautions

Do not use if you are pregnant, breastfeeding or have sitosterolemia.

Risk Information: Not to be used by organ and tissue transplant recipients, including bone marrow and corneal transplants, individuals with a history of diabetes or multiple sclerosis, unless on the advice of and under the direct supervision of a health care practitioner.

Some individuals may experience temporary digestive problems, rashes, headache and fatigue.

DO NOT USE IF SEAL UNDER CAP IS BROKEN.

KEEP OUT OF REACH OF CHILDREN.

General Statements

Helps Support a Healthy Immune System Balance

A Proud Canadian Company

Recommended Use: Helps support a healthy immune system balance.

{Capsule Outline} Actual Size

UPC CODE TO BE: 7 72570 65100 4

Storage

STORE IN A COOL DRY PLACE.

Seals/Symbols

SunOpta A healthy products company

General

665100.01-05

Formulation

This product does not contain corn, dairy, egg, gluten, shellfish, soy, sulfites, animal derivatives or artificial colours, flavours or preservatives.

See for yourself

Moducare by Nature's Harmony label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Moducare by Nature's Harmony

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Beta-sitosterol

No known
interactions
20 mg per serving Form: pine tall oil pitch

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta-sitosterol monograph & interactions

Beta-sitosterolin

No known
interactions
0.2 mg per serving

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta-sitosterolin monograph & interactions

Other (inactive) ingredients: Rice Flour, Magnesium Stearate, Silicon Dioxide, Cellulose, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Moducare by Nature's Harmony Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Moducare. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Moducare, from the product label.

Nature's Harmony

See all Nature's Harmony products
Name
SunOpta Inc.
Street Address
6 Commerce Crescent
City
Acton
State
ON
ZipCode
L7J 2X3
Pharmacist Counseling Corner

Moducare by Nature's Harmony: Common Questions

Does Moducare by Nature's Harmony interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Moducare. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Moducare contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta-sitosterol do?
Beta-sitosterol is a plant sterol that helps support cholesterol levels and prostate health. It's the main active ingredient in this product and has the strongest evidence for helping with an enlarged prostate.
Can I take this if I'm pregnant or breastfeeding?
The safety data isn't there yet, so we recommend avoiding this supplement during pregnancy and breastfeeding. Talk to your doctor or midwife if you want to discuss your options.
What side effects should I watch for?
Most people experience mild digestive symptoms — constipation, diarrhea, gas, indigestion, or nausea. Appetite reduction and acne worsening have also been reported. If you get abdominal pain, stop and check with your pharmacist.
How long does it take to work?
The facts we have don't specify a timeline. Prostate and cholesterol support typically takes weeks to months of consistent use, so talk to your doctor about what to expect for your situation.
Is this safe to take long-term?
The safety data covers short-term use. For long-term use, check with your healthcare provider first — they can monitor you and make sure it's still right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Moducare is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moducare label
Sources

Sources & How We Checked

Moducare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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