No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Beta-Sitosterol Ingredients & Drug Interactions

by Vitabase

Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Beta-Sitosterol is a dietary supplement by Vitabase with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Beta-Sitosterol by Vitabase

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Beta-Sitosterol Complex” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains one active ingredient: beta-sitosterol, a plant sterol (a compound naturally found in plant oils and seeds). The capsule itself is made from gelatin and includes inactive ingredients — magnesium stearate, silica, and cellulose — which are common binders and flow agents.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Support prostate health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis, Lower urinary tract symptoms.
  • The strongest evidence on file: Beta-sitosterol is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Beta-sitosterol is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).

Beta-sitosterol is likely effective for benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate that can cause trouble urinating as men age. It's possibly effective for familial hypercholesterolemia (an inherited condition that raises cholesterol) and coronary heart disease.

The evidence for those last two is suggestive but not conclusive — you might see benefit, but it's not proven across the board.

The evidence, ingredient by ingredient Beta-sitosterol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, beta-sitosterol is generally well tolerated in the short term for most adults. The most common side effects are constipation, diarrhea, gas, indigestion, and nausea.

Some people report reduced appetite. There's also one case report of inflammation of the pancreas (acute pancreatitis) in a person who took it, though the symptoms stopped when he quit — isolated reports like that are noted but aren't proof the supplement caused it.

There isn't enough safety data to know whether it's safe in pregnancy or while breastfeeding, so it's best to avoid it during those times. One caution: beta-sitosterol can worsen acne when taken alone or combined with saw palmetto.

If that's a concern for you, talk it over with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Beta-sitosterol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the beta-sitosterol in this product. Even so, because it affects cholesterol and cardiovascular function, run your medications through the tool on this page before you start, or ask your pharmacist to double-check.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have BPH or want to explore a plant sterol for cholesterol support, beta-sitosterol is a candidate worth discussing with your doctor — it's generally well tolerated and has some evidence behind it for prostate health. Watch for digestive side effects like gas or loose stools, and avoid it if you're pregnant or breastfeeding.

Check with your own pharmacist or doctor before adding it, especially if you're on heart or cholesterol medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta-Sitosterol, straight from the product label.

Brand Vitabase
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 313972
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta-Sitosterol by Vitabase, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Beta-Sitosterol Complex500 mg--
Beta-Sitosterol225 mg--

Other ingredients: Gelatin, Magnesium Stearate, Silica, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: One capsule, taken 1 to 2 times daily with meals as a dietary supplement, or as directed by a health care professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Contains soy (plant sterols).

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Made in the U.S.A.

Formulated to Support Prostate Health

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

See for yourself

Beta-Sitosterol by Vitabase label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Beta-Sitosterol by Vitabase

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Beta-Sitosterol Complex

No known
interactions
500 mg per serving

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta-Sitosterol Complex monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate, Silica, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta-Sitosterol by Vitabase Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Beta-Sitosterol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Beta-Sitosterol, from the product label.

Vitabase

See all Vitabase products
Name
Vitabase.com
City
Monroe
State
GA
ZipCode
30656
Phone Number
888.559.3802
Pharmacist Counseling Corner

Beta-Sitosterol by Vitabase: Common Questions

Does Beta-Sitosterol by Vitabase interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Beta-Sitosterol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Beta-Sitosterol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is beta-sitosterol and why is it in this product?
Beta-sitosterol is a plant sterol — a compound that occurs naturally in plant oils, nuts, and seeds. It's included here because research shows it's likely to help with benign prostatic hyperplasia (BPH), the non-cancerous prostate enlargement that bothers a lot of men as they age.
What side effects should I watch for?
Most people tolerate it well, but you might experience constipation, diarrhea, gas, indigestion, nausea, or reduced appetite. A few people have reported that it can worsen acne, especially if they're also taking saw palmetto. If any of these bother you, stop and talk to your pharmacist.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know whether it's safe, so it's best to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether this is right for you in those situations.
Does it really work for high cholesterol?
The evidence suggests it may help with familial hypercholesterolemia (an inherited high-cholesterol condition) and coronary heart disease, but the data is suggestive rather than conclusive. You might see benefit, but it's not proven for everyone.
Will this interact with my heart or blood pressure medications?
We have no documented interactions in our data for beta-sitosterol with any medications. Even so, because the supplement affects cholesterol and heart function, run your medications through the checker on this page or ask your pharmacist before you start — it's a good habit with any supplement affecting cardiovascular health.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta-Sitosterol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta-Sitosterol label
Go deeper

The Full Monographs Behind Beta-Sitosterol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Beta-Sitosterol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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