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Dietary supplement

Mood Probiotic Ingredients & Drug Interactions

by InnovixLabs

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Mood Probiotic is a dietary supplement by InnovixLabs with 2 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum Rosell-175, Lactobacillus helveticus Rosell-52 ND. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Mood Probiotic by InnovixLabs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Mood Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Mood Probiotic contains 2 active probiotic strains: Bifidobacterium longum Rosell-175 and Lactobacillus helveticus Rosell-52 ND. These are live microorganisms believed to support gut health.

The product also includes inactive ingredients — potato starch, a vegetarian capsule, and magnesium stearate — which serve as fillers and capsule material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support mood and emotional wellness via gut-brain axis.
  • We looked for evidence on: Depression, Generalized anxiety disorder (GAD), Irritable bowel syndrome (IBS), Diarrhea, Antibiotic-associated diarrhea, Abdominal pain — and 4 related terms.
  • The closest evidence on file: Bifidobacterium Longum is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Bifidobacterium Longum is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD), Constipation, Depression, Diarrhea, and more.

The evidence for both Bifidobacterium longum and Lactobacillus helveticus is limited. For Bifidobacterium longum, we have insufficient reliable evidence to rate its use for age-related cognitive decline, hay fever, antibiotic-associated diarrhea, generalized anxiety disorder, asthma, or athletic performance.

For Lactobacillus helveticus, the same picture holds — insufficient evidence to rate it for hay fever, antibiotic-associated diarrhea, cognitive function, depression, rotaviral diarrhea, or exercise-induced respiratory infections. In short, the data we hold doesn't establish effectiveness for the conditions this product may target.

The evidence, ingredient by ingredient Bifidobacterium Longum Lactobacillus Helveticus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both strains are generally well tolerated in healthy people, but caution is needed if you're seriously ill or immune-compromised — talk with your doctor first. Safety data are limited overall, so use this product only with your doctor's guidance.

Rare side effects from Bifidobacterium longum have included abdominal discomfort, pain, distension, flatulence, constipation, and one reported case of a dry cough. There is a small concern that Lactobacillus helveticus preparations could theoretically cause infection in some patients, though most reported cases of bacteremia or sepsis appear linked to bacteria moving from other sites in the body.

Rare cases of serious infection (Bifidobacterium bacteremia or sepsis) have been documented in critically ill infants and premature infants. For pregnancy and breastfeeding, Bifidobacterium longum is rated possibly safe, but limited safety data exist for Lactobacillus helveticus — check with your doctor or pharmacist before using while pregnant or breastfeeding.

Side effects, ingredient by ingredient Bifidobacterium Longum Lactobacillus Helveticus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bifidobacterium Longum, Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Mood Probiotic, double-check your antibiotic medications with your doctor or pharmacist. Antibiotics can reduce the effectiveness of the live organisms in this product, so your healthcare provider will likely recommend taking them at separate times of day.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Mood Probiotic is a two-strain probiotic product with no established effectiveness in the data we hold for its intended purposes. If you take antibiotics, you'll need to space them several hours apart from this product.

Anyone who is seriously ill or has a weakened immune system should talk with their doctor before starting it. Check with your own doctor or pharmacist about whether this product is right for you and how to use it safely alongside your other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mood Probiotic, straight from the product label.

Brand InnovixLabs
Barcode (UPC) X000SNDSGD
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 248223
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mood Probiotic by InnovixLabs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
X000SNDSGD
IngredientAmount% DV
Bifidobacterium longum Rosell-1750 NP--
Mood Probiotic Blend0 NP--
Lactobacillus helveticus Rosell-52 ND0 NP--

Other ingredients: Potato Starch, Vegetarian Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

New Discovery in Probiotic Science New research shows there may be a connection between gut health and mood. Probiotic bacteria in the gut can influence the function and behavior of the brain. This is called the 'gut-brain axis.'

Clinical research has shown that the unique probiotic blend used in InnovixLabs Mood Probiotic may help you: Cope better in stressful situations. Ease digestive discomfort associated with stress. Support positive mood and emotional wellness. Individual results may vary due to the severity of imbalance in gut bacteria, consistency of product use, or if causes are unrelated to gut health. Scientists have identified at least three mechanisms that may help explain the beneficial effect of probiotics on mood and emotions. 1. Probiotics can help reduce establishment of bad bacteria in gut. 2. Probiotics can help support healthy cytokine balance. 3. Probiotics can help support healthy communication with nervous system.

Does Not Contain: Eggs, corn, fish, shellfish, tree nuts, peanuts, wheat/gluten, sugar, GMO, yeast, Chinese ingredients, artificial colors, or flavors.

Stress management support May help ease physical and psychological symptoms of stress May help support positive mood balance

Formulated to provide 15 billion live cultures at time of manufacture, and guaranteed at least 3 billion live cultures at expiry date.

Source: Probiotics are cultivated and encapsulated in Canada. Packaged and tested in USA.

Formula

Two unique strains with clinically studied benefits: Lactobacillus helveticus Rosell-52nd Bifidobacterium longum Rosell-175

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Storage: Store in a cool (75 degrees F or below), dry place. Avoid exposure to high heat and/or moisture.

Storage and handling conditions can affect number of live cultures. Store under recommended conditions. Refrigeration may help maintain high bacteria count.

Precautions

Allergy Information: May contain trace amounts of soy and milk used in the fermentation process. Made in a facility and processed on shared equipment that handles dairy, soy, and gluten. Individuals extremely sensitive to these ingredients should consult a physician prior to using this product.

Warning: If you are pregnant, nursing, or taking any other supplements or medications, talk to your doctor before use.

Not recommended for use by people under the age of 18.

If you experience any adverse reaction, discontinue use and contact your doctor.

Keep out of reach of children.

General Statements

Time for Effect: In clinical studies, those who noticed an effect required a month of regular use. Individual results may vary. Based on clinical research

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1-2 capsules per day with a meal.

Brand IP Statement(s)

2018 Innovix Pharma Inc. All rights reserved.

See for yourself

Mood Probiotic by InnovixLabs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mood Probiotic by InnovixLabs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Mood Probiotic Blend

0 NP per serving

Other (inactive) ingredients: Potato Starch, Vegetarian Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mood Probiotic by InnovixLabs Drug Interactions

Want to check YOUR meds against Mood Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Mood Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium longum Rosell-1751 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D

Lactobacillus helveticus Rosell-52 ND1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Mood Probiotic, from the product label.

InnovixLabs

See all InnovixLabs products
Name
InnovixLabs - A Division of Innovix Pharma Inc.
City
Calabasas
State
CA
ZipCode
91302
Phone Number
888-799-7627
Web Address
www.innovixlabs.com
Pharmacist Counseling Corner

Mood Probiotic by InnovixLabs: Common Questions

Does Mood Probiotic by InnovixLabs interact with any medications?
Yes. Based on its ingredients, Mood Probiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mood Probiotic contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic while I'm on antibiotics?
You can take both, but not at the same time. Antibiotics can kill the live organisms in this product and make it less effective. Ask your doctor or pharmacist to help you space them several hours apart — that way each one does its job without interfering with the other.
Is this product safe if I'm pregnant or breastfeeding?
Bifidobacterium longum is rated possibly safe for pregnancy and lactation, but safety data for Lactobacillus helveticus are limited. Talk with your doctor or pharmacist before using while pregnant or breastfeeding — they can give you personalized advice based on your health.
What are the side effects I should watch for?
Most people tolerate it well. Rarely, users have reported abdominal discomfort, pain, distension, flatulence, constipation, or a dry cough. If you develop severe symptoms, contact your doctor right away.
Is this product safe if I'm seriously ill or have a weak immune system?
No. People who are seriously ill or immune-compromised should be cautious and use this product only under a doctor's guidance. There is a small risk of infection from live probiotics in these situations.
Does this product actually work for anxiety, depression, or cognitive health?
We hold insufficient reliable evidence to rate either strain for those uses. The data don't establish whether it works for anxiety, depression, cognitive function, or the other conditions it may be marketed for.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mood Probiotic is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mood Probiotic label
Sources

Sources & How We Checked

Mood Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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