Multiple Fiber Formula Ingredients & Drug Interactions
by Solgar
What is this page for?
First and foremost: checking Multiple Fiber Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Multiple Fiber Formula is a dietary supplement by Solgar with 5 active ingredients. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 603 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Flaxseed Meal, Apple Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Multiple Fiber Formula by Solgar
Ask about any prescription or over-the-counter medication and we check it for interactions with Multiple Fiber Formula by Solgar — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Multiple Fiber Formula by Solgar
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 5 of its 5 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Pectin, Flaxseed.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
- For scale: 603 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Multiple Fiber Formula, straight from the product label.
| Brand | Solgar |
|---|---|
| Barcode (UPC) | 033984017870 |
| Net contents | 120 Vegetable Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Apr 24, 2015 |
| DSLD ID | 44694 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Multiple Fiber Formula by Solgar, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Oat Bran | 200 mg | -- |
| Apple Pectin | 200 mg | -- |
| Grapefruit Pectin | 200 mg | -- |
| Flaxseed Meal | 200 mg | -- |
| Psyllium | 200 mg | -- |
Other ingredients: Vegetable Cellulose, Vegetable Magnesium Stearate, Silica, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Solgar’s Multiple Fiber Formula Vegetable Capsules are free of corn, yeast, wheat, soy and dairy products and are formulated without the use of preservatives, artificial flavors or colors.
SUITABLE FOR VEGETARIANS
SUGAR, SALT AND STARCH FREE
Storage
To assure freshness and potency, store at room temperature 15(0)-30(0)C (59(0)-86(0)F). Store away from heat, light and moisture.
Formula
Formulated for adults.
Precautions
Keep out of reach of children.
If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement.
DO NOT USE IF OUTER BOTTLE SEAL IS MISSING, TORN OR DAMAGED IN ANY WAY.
FDA Statement of Identity
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
DIETARY SUPPLEMENT
General
01787US01KJ
General Statements
Since 1947
GASTROINTESTINAL SUPPORT*
Suggested/Recommended/Usage/Directions
SUGGESTED USE: As a dietary supplement for adults, two (2) to six (6) vegetable capsules daily with 8 oz. of water, distributed throughout the day, preferably away from meals, or as directed by a healthcare practitioner
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Multiple Fiber Formula by Solgar label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Multiple Fiber Formula by Solgar
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Oat Bran
Apple Pectin
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Apple Pectin monograph & interactionsGrapefruit Pectin
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Grapefruit Pectin monograph & interactionsFlaxseed Meal
Interacts with597 drugs
Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and...
Flaxseed Meal monograph & interactionsPsyllium
Other (inactive) ingredients: Vegetable Cellulose, Vegetable Magnesium Stearate, Silica, Water. These complete the product’s ingredient list but are not active constituents.
Multiple Fiber Formula by Solgar Drug Interactions
Multiple Fiber Formula contains 5 ingredients, and 2 of them have known drug interactions. Altogether they interact with 603 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Multiple Fiber Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Multiple Fiber Formula interact with 603 drugs. Click any drug to see the details.
2 of the 5 ingredients in Multiple Fiber Formula interact with drugs. Each result below shows which ingredient is responsible. Flaxseed Meal Apple Pectin
AbciximabReoPro
How Abciximab interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Ambrisentan interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntibiotic Drugs Moderate
Interaction Summary
Theoretically, antibiotics might interfere with the metabolism of flaxseed constituents, which could potentially alter the effects of flaxseed.
Read the full Flaxseed Meal + Amikacin interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Multiple Fiber Formula — through 1 ingredient. Tap an ingredient for the detail:
Flaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Ammonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Multiple Fiber Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Flaxseed Meal
Antibiotic Drugs
Theoretically, antibiotics might interfere with the metabolism of flaxseed constituents, which could potentially alter the effects of flaxseed.
Some potential benefits of flaxseed are thought to be due to its lignan content. Secoisolariciresinol diglucoside (SDG), a major lignan precursor, is found in high concentrations in flaxseed. SDG is converted by bacteria in the colon to the lignans enterolactone and enterodiol. Antibiotics alter the flora of the colon, which could theoretically alter the metabolism of flaxseed.
Anticoagulant/Antiplatelet Drugs
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Some clinical evidence suggests that the oil contained in flaxseed can decrease platelet aggregation.
Antidiabetes Drugs
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Some clinical research suggests that flaxseed can lower blood glucose levels.
Antihypertensive Drugs
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Clinical research shows that daily flaxseed consumption, especially for longer than 12 weeks, modestly reduces blood pressure.
Estrogens
Theoretically, taking flaxseed might decrease the effects of estrogens.
Flaxseed contains lignans with mild estrogenic and possible antiestrogenic effects. The lignans seem to compete with circulating endogenous estrogen and might reduce estrogen binding to estrogen receptors, resulting in an anti-estrogen effect. It is unclear if this effect transfers to exogenously administered estrogens.
Apple Pectin
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Brand information
Manufacturer and brand details for Multiple Fiber Formula, from the product label.
Multiple Fiber Formula by Solgar: Common Questions
Does Multiple Fiber Formula by Solgar interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Multiple Fiber Formula is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Multiple Fiber Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Pectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph → Herb & supplement monographFlaxseed
Interacts with 597 drugsFlaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and may modestly lower cholesterol, but evid...
Read the full Flaxseed monograph →Sources & How We Checked
Multiple Fiber Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 48 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pectin 11 references
- Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
- Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
- Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
- Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
- Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
- Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
- Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
- Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
- Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
Flaxseed 37 references
- Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
- Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
- Thompson LU, Rickard SE, Cheung F, et al. Variability in anticancer lignan levels in flaxseed. Nutr Cancer 1997;27:26-30. PubMed
- Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol Int 1995;14:231-4. PubMed
- Cunnane SC, Ganguli S, Menard C, et al. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Br J Nutr 1993;69:443-53.
- Clark WF, Parbtani A, Huff MW, et al. Flaxseed: a potential treatment for lupus nephritis. Kidney Int 1995;48:475-80. PubMed
- Cunnane SC, Hamadeh MJ, Liede AC, et al. Nutritional attributes of traditional flaxseed in healthy young adults. Am J Clin Nutr 1995;61:62-8. PubMed
- De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
- Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
- Clark WF, Kortas C, Heidenheim P, et al. Flaxseed in lupus nephritis: a two-year nonplacebo-controlled crossover study. J Am Coll Nutr 2001;20:143-8. PubMed
- Serraino M, Thompson LU. The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Lett 1991;60:135-42. PubMed
- Rickard SE, Yuan YV, Thompson LU. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Cancer Lett 2000;161:47-55. PubMed
- Mousavi Y, Adlercreutz H. Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. J Steroid Biochem Mol Biol 1992;41:615-9.. PubMed
- Adlercreutz H, Fotsis T, Bannwart C, et al. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. J Steroid Biochem 1986;25:791-7.. PubMed
- Rose DP. Dietary fiber and breast cancer. Nutr Cancer 1990;13:1-8.. PubMed
- Lemay A, Dodin S, Kadri N, et al. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. Obstet Gynecol 2002;100:495-504.. DOI
- Brooks JD, Ward WE, Lewis JE, et al. Supplementation with flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than does supplementation with an equal amount of soy. Am J Clin Nutr 2004;79:318-25.. PubMed
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