MycoShield Spray Peppermint Ingredients & Drug Interactions
What is this page for?
First and foremost: checking MycoShield Spray Peppermint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
MycoShield Spray Peppermint is a dietary supplement by Host Defense Mushrooms with 5 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 501 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mycelium Extract, Fresh, Chaga Mycelium Extract, Fresh, Birch Polypore Mycelium Extract, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against MycoShield Spray Peppermint by Host Defense Mushrooms
Ask about any prescription or over-the-counter medication and we check it for interactions with MycoShield Spray Peppermint by Host Defense Mushrooms — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of MycoShield Spray Peppermint by Host Defense Mushrooms
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
MycoShield Spray contains 5 active ingredients: mushroom mycelium extracts from Agarikon, Reishi, Chaga, Birch Polypore, and Turkey Tail, delivered in a proprietary blend. The product also includes water, alcohol, and peppermint essential oil as inactive ingredients.
Does it work?
Not established
The data we hold on these mushroom extracts shows insufficient reliable evidence to rate their effectiveness for the conditions they're marketed toward. Chaga's effectiveness for cardiovascular disease, diabetes, and COVID-19 is not established in our records.
Birch Polypore likewise has insufficient evidence for joint pain, hair loss, or dandruff. We don't have effectiveness information on file for Agarikon, Reishi, or Turkey Tail.
How safe is it?
Well-documented data
Chaga is generally used in foods and teas, but human safety data are limited. There are a few reported cases: two of kidney failure and one of acute kidney injury linked to very high chaga consumption—chaga contains high amounts of oxalate.
The safety data advises against chaga during pregnancy and breastfeeding. Birch polypore is generally well tolerated in food-like amounts, but allergic reactions are possible; birch and birch pollen can trigger allergies, and rare cases of allergic contact dermatitis have been reported.
Safety data advises against birch during pregnancy and breastfeeding. We don't have adverse-effect or safety data on file for the other three mushroom extracts.
Meds to double-check
Moderate interaction found
Before you use this spray, double-check if you take anticoagulant or antiplatelet drugs (blood thinners like warfarin or clopidogrel)—chaga may increase bleeding risk. Also flag any diabetes medications, immunosuppressants, or diuretics.
No interactions are documented for the other mushroom ingredients we hold data on.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This is a mushroom-based spray with limited evidence of effectiveness and some theoretical medication interactions we can document. If you take blood thinners, diabetes medications, immunosuppressants, or diuretics, check your exact meds with the tool on this page before you start.
Anyone with a birch or mushroom allergy should be cautious. Talk to your pharmacist about whether it fits your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about MycoShield Spray Peppermint, straight from the product label.
| Brand | Host Defense Mushrooms |
|---|---|
| Net contents | 0.5 Fluid Ounce(s); 15 mL |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 312406 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for MycoShield Spray Peppermint by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 0.42 mL | -- |
| Agarikon Mycelium Extract, Fresh | 0 NP | -- |
| Reishi Mycelium Extract, Fresh | 0 NP | -- |
| Chaga Mycelium Extract, Fresh | 0 NP | -- |
| Birch Polypore Mycelium Extract, Fresh | 0 NP | -- |
| Turkey Tail Mycelium Extract, Fresh | 0 NP | -- |
Other ingredients: Water, Alcohol, Peppermint Essential Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Apply three pump sprays into mouth ,then swallow, twice per day. Shake well before using. Can be taken with food, on an empty stomach, or as recommended by your healthcare professional.
Precautions
Do not inhale while spraying. Avoid contact with eyes.
Caution: If you have a medical condition, are taking medications, or are pregnant or breastfeeding, consult a healthcare professional before using this product.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Superfood mushroom mycelium
FDA Statement of Identity
Dietary Supplement
Formulation
On-the-go immune support
Certified Organic by the WSDA
Seals/Symbols
Certified Organic Washington State Department of Agriculture Organic Program
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
MycoShield Spray Peppermint by Host Defense Mushrooms label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in MycoShield Spray Peppermint by Host Defense Mushrooms
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.42 mL Dosage formLiquid Servings per container35 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Agarikon Mycelium Extract, Fresh
- › Reishi Mycelium Extract, Fresh
- › Chaga Mycelium Extract, Fresh
- › Birch Polypore Mycelium Extract, Fresh
- › Turkey Tail Mycelium Extract, Fresh
Other (inactive) ingredients: Water, Alcohol, Peppermint Essential Oil. These complete the product’s ingredient list but are not active constituents.
MycoShield Spray Peppermint by Host Defense Mushrooms Drug Interactions
HelloPharmacist Interaction Report
MycoShield Spray Peppermint from Host Defense Mushrooms contains mushroom extracts, and we can document interactions for two of them.
Chaga carries the most serious concern: it may increase bleeding risk if you take anticoagulant or antiplatelet drugs (blood thinners like warfarin or aspirin). This is theoretical—based on lab and animal work, not yet seen in people—but worth checking.
Read the full breakdown — every affected drug type, severity by severity
Chaga also theoretically raises the risk of low blood sugar (hypoglycemia) with diabetes medications and might interfere with immunosuppressants. Birch polypore is associated with a minor theoretical interaction: it may interfere with diuretic therapy (water pills).
We could not check three other ingredients: Agarikon, Reishi, and Turkey Tail mushroom extracts. That doesn't mean they interact with nothing—just that we hold no data for them.
Altogether, these interactions span 397 individual medications. Before you use this spray, run your exact medications through the checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against MycoShield Spray Peppermint?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in MycoShield Spray Peppermint interact with 501 drugs. Click any drug to see the details.
3 of the 5 ingredients in MycoShield Spray Peppermint interact with drugs. Each result below shows which ingredient is responsible. Reishi Mycelium Extract, Fresh Chaga Mycelium Extract, Fresh Birch Polypore Mycelium Extract, Fresh
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Abciximab interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Abrocitinib interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga Mycelium Extract, Fresh + Acarbose interactionReishi Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mycelium Extract, Fresh + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Acenocoumarol interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Acetaminophen, Aspirin interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Acetaminophen, Aspirin, Caffeine interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Acetaminophen, Ibuprofen interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Acetazolamide interactionBirch Polypore Mycelium Extract, FreshDiuretic Drugs Minor
Interaction Summary
Theoretically, birch might interfere with diuretic therapy.
Read the full Birch Polypore Mycelium Extract, Fresh + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mycelium Extract, Fresh + Acetohexamide interactionChaga Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga Mycelium Extract, Fresh + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Acetylsalicylic Acid interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga Mycelium Extract, Fresh + Albiglutide interactionReishi Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mycelium Extract, Fresh + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, chaga might interfere with immunosuppressive therapy.
Read the full Chaga Mycelium Extract, Fresh + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mycelium Extract, Fresh + Alogliptin interactionChaga Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga Mycelium Extract, Fresh + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga Mycelium Extract, Fresh + Alogliptin, Metformin interactionReishi Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mycelium Extract, Fresh + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Mycelium Extract, Fresh + Alogliptin, Pioglitazone interactionChaga Mycelium Extract, FreshAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Chaga Mycelium Extract, Fresh + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Alteplase, Tpa interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionChaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with MycoShield Spray Peppermint — through 2 ingredients. Tap an ingredient for the detail:
Chaga Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chaga Mycelium Extract, Fresh + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionReishi Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Mycelium Extract, Fresh + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with MycoShield Spray Peppermint — through 1 ingredient. Tap an ingredient for the detail:
Reishi Mycelium Extract, FreshAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Mycelium Extract, Fresh + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in MycoShield Spray Peppermint with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Reishi Mycelium Extract, Fresh
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Chaga Mycelium Extract, Fresh
Anticoagulant/Antiplatelet Drugs
Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.
Immunosuppressants
Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.
Birch Polypore Mycelium Extract, Fresh
Diuretic Drugs
Theoretically, birch might interfere with diuretic therapy.
Brand information
Manufacturer and brand details for MycoShield Spray Peppermint, from the product label.
Host Defense Mushrooms
See all Host Defense Mushrooms products- Name
- Fungi Perfecti, LLC
- Street Address
- PO Box 7634
- City
- Olympia
- State
- WA
- ZipCode
- 98507
- Phone Number
- 877-504-6926
- Web Address
- Hostdefense.com
MycoShield Spray Peppermint by Host Defense Mushrooms: Common Questions
Does MycoShield Spray Peppermint by Host Defense Mushrooms interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I use MycoShield Spray if I'm pregnant or breastfeeding?
Is this spray proven to work?
What is Chaga, and why is there a bleeding concern?
Can Chaga affect my blood sugar?
I'm allergic to birch pollen—should I avoid this spray?
What are the inactive ingredients in this spray?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if MycoShield Spray Peppermint is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind MycoShield Spray Peppermint’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Reishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph → Herb & supplement monographChaga
Interacts with 327 drugsChaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...
Read the full Chaga monograph → Herb & supplement monographBirch
Interacts with 75 drugsBirch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...
Read the full Birch monograph →Sources & How We Checked
MycoShield Spray Peppermint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
- Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
- Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
- Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
- Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
- Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
- Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
- Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
- Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
- Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
- Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
- Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
- Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
- Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
- Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.
Chaga 9 references
- Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
- Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
- Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
- Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
- Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
- Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
- Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
- Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
- Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed
Birch 4 references
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
- Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
- Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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