Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Myo & D-Chiro Inositol Ingredients & Drug Interactions

by Nature's Craft

Myo & D-Chiro Inositol label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Myo & D-Chiro Inositol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Myo & D-Chiro Inositol is a dietary supplement by Nature's Craft with 3 active ingredients. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 102 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are MyoNositol, Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Myo & D-Chiro Inositol by Nature's Craft

Ask about any prescription or over-the-counter medication and we check it for interactions with Myo & D-Chiro Inositol by Nature's Craft — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Myo & D-Chiro Inositol by Nature's Craft

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains 3 active ingredients: choline, MyoInositol, and Carob-sitol (a form of inositol). Choline is a nutrient involved in cell signaling and brain function.

The two inositol forms are naturally occurring compounds that play roles in cell signaling and metabolism, and together they're often used as a combination for hormonal and metabolic support. The capsule itself is made from gelatin as an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Polycystic ovary syndrome (PCOS) — rated "Possibly Effective" (Inositol) (Natural Medicines).
  • On file: Preterm labor — rated "Possibly Effective" (Inositol) (Natural Medicines).
  • On file: Metabolic syndrome — rated "Possibly Effective" (Inositol) (Natural Medicines).

MyoInositol and Carob-sitol are both rated possibly effective for polycystic ovary syndrome (PCOS), metabolic syndrome, and preterm labor. They're rated possibly ineffective for anxiety, diabetic nerve damage, and depression.

Choline's effectiveness is less clear for the conditions where it's been studied—athletic performance is rated possibly ineffective, and there's insufficient evidence to rate it for bronchitis, age-related cognitive decline, liver fat from IV nutrition, hay fever, or Alzheimer's disease.

The evidence, ingredient by ingredient Choline Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both inositol forms are generally well tolerated at common doses, with the most common side effects being digestive: diarrhea, gas, and nausea. Choline is also generally safe in food amounts, but high-dose supplements can cause a fishy body odor, and very high doses (9 grams daily or more) may trigger diarrhea, nausea, salivation, sweating, and vomiting—it has a daily upper limit of 3.5 grams.

For pregnancy, MyoInositol and Carob-sitol are rated possibly safe, though they've been studied in pregnancy only under medical supervision and safety isn't fully established—talk with your doctor about use. Choline is rated likely safe in pregnancy and is actually important during pregnancy, but prenatal or supplement doses should only be taken as your doctor advises.

Breastfeeding data for inositol isn't on file; for choline, your needs are higher while breastfeeding and supplements should be used only under professional guidance.

Side effects, ingredient by ingredient Choline Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Inositol, Choline.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 102 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use antidiabetes drugs (Moderate risk: inositol may increase low blood sugar), or atropine (Minor risk: choline might decrease its effects). No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with PCOS, metabolic syndrome, or preterm labor based on the inositol content, though the evidence is modest. If you take diabetes medications or atropine, you'll want to check this combination with your doctor or pharmacist first—the inositol could lower your blood sugar further.

It's generally well tolerated, but be aware digestive side effects and a fishy odor are possible at higher intakes. Talk it over with your own healthcare provider to see if it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Myo & D-Chiro Inositol, straight from the product label.

Brand Nature's Craft
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 296713
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Myo & D-Chiro Inositol by Nature's Craft, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Choline500 mg91%
MyoNositol500 mg--
Carob-sitol25 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: For adults, take one (1) to two (2) capsules daily before a meal, or as directed by your physician. Do not take more than two (2) capsules per day.

Precautions

Caution: Do not exceed suggested dose.

Pregnant or nursing mothers, children under 18, or individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, or individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Carob-sitol & MyoNositol are registered trademarks of SQ Ingredients, LLC.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

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Formula

Myo & D-Chiro Inositol + with Choline

Women's Wellness

Formulation

Fertility Hormones Cycle Mood Heart Health

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in the USA with Global Ingredients Made in an FDA Inspected Facility 3rd Party Lab Verified Sourced from a GMP Certified Facility

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Myo & D-Chiro Inositol by Nature's Craft label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Myo & D-Chiro Inositol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Myo & D-Chiro Inositol by Nature's Craft

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Choline

Interacts with
16 drugs
500 mg per serving Form: Choline Bitartrate

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

MyoNositol

Interacts with
86 drugs
500 mg per serving Form: Myo-Inositol

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

MyoNositol monograph & interactions

Carob-sitol

Interacts with
86 drugs
25 mg per serving Form: D-Chiro Inositol

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Carob-sitol monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Myo & D-Chiro Inositol by Nature's Craft Drug Interactions

Want to check YOUR meds against Myo & D-Chiro Inositol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
102Drugs
86 Moderate 16 Minor

Ingredients driving the most interactions

MyoNositol 86
Choline 16

Individual Drug Interactions

The ingredients in Myo & D-Chiro Inositol interact with 102 drugs. Click any drug to see the details.

2 of the 3 ingredients in Myo & D-Chiro Inositol interact with drugs. Each result below shows which ingredient is responsible. MyoNositol Choline

Each ingredient & the kinds of drugs it affects

For each ingredient in Myo & D-Chiro Inositol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

MyoNositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
MyoNositol full monograph & interactions

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Myo & D-Chiro Inositol, from the product label.

Nature's Craft

See all Nature's Craft products
Name
Nature's Craft
Street Address
91 Overlook Rd
City
Pomona
State
NY
ZipCode
10970
Phone Number
408-599-3841
Web Address
shopnaturescraft.com
Pharmacist Counseling Corner

Myo & D-Chiro Inositol by Nature's Craft: Common Questions

Does Myo & D-Chiro Inositol by Nature's Craft interact with any medications?
Yes. Based on its ingredients, Myo & D-Chiro Inositol has a known interaction with 102 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Myo & D-Chiro Inositol contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this okay to take if I'm pregnant?
MyoInositol and Carob-sitol are rated possibly safe in pregnancy, and choline is rated likely safe—choline is actually important during pregnancy. But the safety data for inositol in pregnancy isn't fully established. Talk with your doctor before starting it to make sure it fits your individual situation.
Can I take this while breastfeeding?
Choline needs are higher while breastfeeding, but supplements should only be used under professional guidance. We don't have breastfeeding safety data on file for the inositol forms. Check with your doctor or pharmacist before taking it.
What are the most common side effects?
Digestive upset—diarrhea, gas, and nausea—is the most common, especially with the inositol. At very high doses, choline can also cause a fishy body odor.
Will this help my PCOS?
Both inositol forms are rated possibly effective for PCOS, so they may help. The evidence is there, but talk with your doctor about whether this product is right for your treatment plan.
What does each ingredient do?
Choline supports cell signaling and brain function. MyoInositol and Carob-sitol (both inositol forms) work on cell signaling and metabolism, and are often combined together for hormonal and metabolic support.
Can I take this with my diabetes medication?
Inositol can lower blood sugar on its own, so combining it with antidiabetes drugs carries a Moderate risk of low blood sugar (hypoglycemia). Check with your doctor or pharmacist before taking it—they can help you figure out whether it's safe for you and whether your dose needs adjusting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Myo & D-Chiro Inositol is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Myo & D-Chiro Inositol label
Go deeper

The Full Monographs Behind Myo & D-Chiro Inositol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph → Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Myo & D-Chiro Inositol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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