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Dietary supplement

Natural Potassium Gluconate 550 mg Ingredients & Drug Interactions

by Sunmark

Natural Potassium Gluconate 550 mg label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Natural Potassium Gluconate 550 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Natural Potassium Gluconate 550 mg is a dietary supplement by Sunmark with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Natural Potassium Gluconate 550 mg by Sunmark

Ask about any prescription or over-the-counter medication and we check it for interactions with Natural Potassium Gluconate 550 mg by Sunmark — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Natural Potassium Gluconate 550 mg by Sunmark

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: potassium, supplied as potassium gluconate at 550 mg per tablet. The inactive ingredients are cellulose, corn starch, croscarmellose sodium, silicon dioxide, stearic acid, and magnesium stearate — standard tablet binders and flow agents.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Potassium product and its label doesn't state a use — see Potassium's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The product facts we hold do not include effectiveness ratings for potassium supplementation, so we cannot speak to how well it works or for what specific purposes the evidence supports its use.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe, but supplements can push your blood levels dangerously high in some people — especially those with kidney disease. Orally, the most common side effects are stomach upset: abdominal pain, belching, diarrhea, flatulence, nausea, and vomiting.

Rare but serious effects of very high potassium include irregular heartbeat, low blood pressure, heart block, or even cardiac arrest. During pregnancy, dietary potassium is appropriate, but use supplements only under medical guidance.

The same applies to breastfeeding — check with your doctor or pharmacist before taking this supplement while nursing.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take a potassium-sparing diuretic (moderate risk of high blood potassium), an ACE inhibitor, or an ARB (both moderate risk). These are the medication types where documented interactions exist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take a potassium-sparing diuretic, ACE inhibitor, or ARB, you must clear this supplement with your doctor or pharmacist first — the combination can dangerously raise your blood potassium. Even if you don't take those drugs, kidney disease is a red flag.

Talk it over with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 26, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natural Potassium Gluconate 550 mg, straight from the product label.

Brand Sunmark
Barcode (UPC) 010939453334
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Apr 26, 2012
DSLD ID 7746
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natural Potassium Gluconate 550 mg by Sunmark, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
010939453334
IngredientAmount% DV
Potassium90 mg3%

Other ingredients: Potassium Gluconate, Cellulose, Corn Starch, Croscarmellose Sodium, Silicon Dioxide, Stearic Acid, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take one tablet daily with a full glass of water, preferably after a meal.

Precautions

Keep out of the reach of children.

Storage

Keep in a cool dry place, tightly closed.

Formulation

NO PRESERVATIVES ADDED NO LACTOSE NO ARTIFICIAL COLOR OR FLAVOR NO GLUTEN

General Statements

49348-055-10

Money Back Guarantee

PRODUCT BENEFIT Helps retain already healthy blood pressure and is essential for muscle contractions and proper nerve function.

Potassium Gluconate Tablets USP.

FRESHNESS AND POTENCY GUARANTEED THROUGH:

USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplements. See www.uspverified.org

Seals/Symbols

DIETARY SUPPLEMENT USP VERIFIED(TM)

McKESSON Empowering Healthcare

Formula

(Equivalent to 90mg Potassium)

FDA Statement of Identity

DIETARY SUPLEMENT

General

SUN3230A06

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Natural Potassium Gluconate 550 mg by Sunmark label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Natural Potassium Gluconate 550 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Natural Potassium Gluconate 550 mg by Sunmark

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Potassium

Interacts with
62 drugs
90 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Potassium Gluconate, Cellulose, Corn Starch, Croscarmellose Sodium, Silicon Dioxide, Stearic Acid, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natural Potassium Gluconate 550 mg by Sunmark Drug Interactions

Want to check YOUR meds against Natural Potassium Gluconate 550 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Natural Potassium Gluconate 550 mg interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Natural Potassium Gluconate 550 mg interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Natural Potassium Gluconate 550 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Natural Potassium Gluconate 550 mg, from the product label.

Sunmark

See all Sunmark products
Name
McKesson
Street Address
One Post Street
City
San Francisco
State
CA
ZipCode
94104
Pharmacist Counseling Corner

Natural Potassium Gluconate 550 mg by Sunmark: Common Questions

Does Natural Potassium Gluconate 550 mg by Sunmark interact with any medications?
Yes. Based on its ingredients, Natural Potassium Gluconate 550 mg has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natural Potassium Gluconate 550 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have kidney disease?
No — the safety data specifically cautions that supplements can cause dangerously high blood potassium in people with kidney disease. Talk with your doctor or pharmacist about whether you need a potassium supplement and how to use it safely.
What are the most common side effects?
Stomach upset: abdominal pain, belching, diarrhea, flatulence, nausea, and vomiting. These tend to happen when taken orally.
Is potassium safe to take during pregnancy?
Dietary potassium is fine, but supplements are not recommended without medical guidance during pregnancy. Talk with your doctor before starting this supplement if you're pregnant or planning to be.
What does potassium gluconate do?
It's a form of potassium — an electrolyte your body needs for heart and muscle function. This product supplies potassium at 550 mg per tablet, but the product facts we hold don't specify the clinical conditions it's meant to treat.
Can serious side effects happen?
Yes, though they're rare. Very high potassium levels can cause an irregular heartbeat, low blood pressure, heart block, or cardiac arrest. If you feel chest pain, shortness of breath, or severe dizziness, seek emergency care immediately.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Natural Potassium Gluconate 550 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natural Potassium Gluconate 550 mg label
Go deeper

The Full Monographs Behind Natural Potassium Gluconate 550 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Natural Potassium Gluconate 550 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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