Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Neuro-PS 300 mg Triple Strength Ingredients & Drug Interactions

by Vitamin World

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Neuro-PS 300 mg Triple Strength is a dietary supplement by Vitamin World with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Neuro-PS(R). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Neuro-PS 300 mg Triple Strength by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Neuro-PS(R)” is listed as a grouped ingredient — the label gives one combined amount (432 mg) without saying how much of each component you get.

Neuro-PS 300 mg Triple Strength contains one active ingredient: phosphatidylserine, a naturally occurring compound in your brain and nerve cells that plays a role in cell communication. It's standardized to deliver 300 mg of phosphatidylserine per softgel.

The product also contains inactive ingredients (soybean oil, gelatin, vegetable glycerin, and soy lecithin) that make up the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: healthy mind.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive function, Dementia, Attention deficit-hyperactivity disorder (ADHD), mental clarity — and 2 related terms.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Possibly Effective" for Alzheimer disease.
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Dementia.

Phosphatidylserine is possibly effective for slowing age-related cognitive decline and possibly effective for Alzheimer disease, based on the evidence we hold. For athletic performance, ADHD, general cognitive function, and dementia, the evidence isn't yet established well enough to rate it reliably.

If you're considering this supplement for any of those conditions, talk it through with your doctor or pharmacist to see if the current research fits your situation.

The evidence, ingredient by ingredient Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylserine is generally well tolerated in studies, though long-term safety hasn't been fully mapped out. The most common side effects are flatulence, gastrointestinal upset, headache, insomnia, and nausea.

Insomnia and headache may be more likely at higher doses, and gastrointestinal upset can occur at doses around 200–300 mg per day (the dose in this product). There is not enough safety information to recommend this supplement during pregnancy, and safety while breastfeeding is unknown — if you're pregnant or nursing, talk with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, confirm with your doctor or pharmacist if you're on any anticholinergic drugs (used for overactive bladder, Parkinson's, and certain poisonings) or cholinergic drugs (like donepezil for Alzheimer's or pilocarpine). Both have Moderate-severity interactions with phosphatidylserine that could affect how your medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement may be worth considering if you're interested in supporting cognitive health and age-related memory changes, but it's not established for many other brain-related uses. If you take any anticholinergic or cholinergic medication (including Alzheimer's drugs), check with your doctor or pharmacist before adding it.

Side effects are usually mild but can include stomach upset and sleep problems, especially at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Neuro-PS 300 mg Triple Strength, straight from the product label.

Brand Vitamin World
Barcode (UPC) 766443176305
Net contents 60 Rapid Release Softgel(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 20570
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Neuro-PS 300 mg Triple Strength by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
766443176305
IngredientAmount% DV
Neuro-PS(R)432 mg--
Standardized to contain Phosphatidylserine300 mg--

Other ingredients: Soybean Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Contains <2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

HEALTHY MIND*

TRIPLE STRENGTH Healthy Mind* Aids Brain Function, Supports a Healthy Mind and Helps Replenish PS levels* ONE PER DAY

This product has been developed, manufactured and packaged by Vitamin World. Our world-class facilities allow us to control exactly what goes into each product. It is your assurance that you are getting the highest quality and freshest products. You have our guarantee!

Precautions

Do not use if seal under cap is broken or missing.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store at room temperature.

Brand IP Statement(s)

(C)2012 Vitamin World, Inc.

General

PROD. #17630 B17631 04B

Seals/Symbols

V VITAMIN WORLD(R) get healthy.

QA QUALITY ASSURED

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) softgel daily, preferably with a meal.

Formulation

No Artificial Flavor or Sweetener, No Preservatives, No Starch, No Milk, No Lactose, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Formula

Phosphatidylserine

See for yourself

Neuro-PS 300 mg Triple Strength by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Neuro-PS 300 mg Triple Strength by Vitamin World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Neuro-PS(R)

Interacts with
219 drugs
432 mg per serving Form: Soy Lecithin

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Neuro-PS(R) monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Contains <2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Neuro-PS 300 mg Triple Strength by Vitamin World Drug Interactions

Want to check YOUR meds against Neuro-PS 300 mg Triple Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Neuro-PS 300 mg Triple Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Neuro-PS(R)2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Neuro-PS 300 mg Triple Strength, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Pharmacist Counseling Corner

Neuro-PS 300 mg Triple Strength by Vitamin World: Common Questions

Does Neuro-PS 300 mg Triple Strength by Vitamin World interact with any medications?
Yes. Based on its ingredients, Neuro-PS 300 mg Triple Strength has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Neuro-PS 300 mg Triple Strength contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylserine and what does it do?
Phosphatidylserine is a compound naturally found in your brain and nerve cells that helps them communicate with each other. This supplement delivers it in a concentrated form to support brain health.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety information to recommend this supplement during pregnancy, and safety while breastfeeding is unknown. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.
What side effects should I watch for?
Most common side effects are mild: flatulence, stomach upset, headache, insomnia, and nausea. Insomnia is more likely at higher doses, and stomach upset can occur at the 300 mg dose in this product.
Does this really help with memory and brain function?
Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease based on available evidence. For other uses like ADHD or general cognition, the evidence isn't established well enough yet.
Is this product soy-free?
No — this product contains soybean oil and soy lecithin as inactive ingredients. If you have a soy allergy, this product is not for you.
Why do I need to tell my doctor about this if I'm on certain medications?
Phosphatidylserine can theoretically interfere with how anticholinergic and cholinergic drugs work by affecting acetylcholine, a key brain chemical. Your doctor or pharmacist needs to know whether those interactions matter for your specific medications and situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Neuro-PS 300 mg Triple Strength is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Neuro-PS 300 mg Triple Strength label
Go deeper

The Full Monographs Behind Neuro-PS 300 mg Triple Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Neuro-PS 300 mg Triple Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring