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Dietary supplement

Neuro-PS Phosphatidylserine 200 mg Ingredients & Drug Interactions

by Vitamin World

Neuro-PS Phosphatidylserine 200 mg label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Neuro-PS Phosphatidylserine 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Neuro-PS Phosphatidylserine 200 mg is a dietary supplement by Vitamin World with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Neuro-PS. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Neuro-PS Phosphatidylserine 200 mg by Vitamin World

Ask about any prescription or over-the-counter medication and we check it for interactions with Neuro-PS Phosphatidylserine 200 mg by Vitamin World — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Neuro-PS Phosphatidylserine 200 mg by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: phosphatidylserine (200 mg per softgel). Phosphatidylserine is a naturally occurring fat-like substance found in cell membranes throughout your body, including your brain.

The supplement comes in a softgel capsule made with gelatin, medium chain triglycerides, vegetable glycerin, and natural caramel color as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: brain function and healthy mind support.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Alzheimer disease, Dementia, Memory, Mental clarity — and 1 related terms.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Possibly Effective" for Alzheimer disease.
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Dementia.

Phosphatidylserine is possibly effective for age-related cognitive decline and Alzheimer disease, based on the evidence we hold. For other uses — athletic performance, ADHD, general cognitive function, and dementia — the evidence isn't strong enough to rate whether it works.

If you're considering this for a specific condition, talk with your pharmacist or doctor about what the research shows for your situation.

The evidence, ingredient by ingredient Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylserine is generally well tolerated when taken by mouth. The most common side effects are flatulence, gastrointestinal upset, headache, insomnia, and nausea.

Insomnia is more likely at higher doses (around 600 mg), and gastrointestinal upset can happen at the dose in this product (200 mg daily). Long-term safety hasn't been fully established in studies.

There isn't enough safety information to recommend this during pregnancy or while breastfeeding. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist before using this supplement.

Side effects, ingredient by ingredient Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take anticholinergic drugs (used for overactive bladder, certain muscle stiffness, or digestive issues) or cholinergic drugs (like those for myasthenia gravis) — both are Moderate severity concerns. Use the search tool on this page to look up your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Neuro-PS might help with age-related memory changes or Alzheimer disease if the evidence supports your situation. Anyone taking anticholinergic or cholinergic medications should check their exact drugs with our tool first.

If you're pregnant, nursing, or have questions about whether this fits your health, talk with your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Neuro-PS Phosphatidylserine 200 mg, straight from the product label.

Brand Vitamin World
Barcode (UPC) 766443165392
Net contents 60 Rapid Release Softgel(s)
Market status On market
Date entered into DSLD Oct 22, 2016
DSLD ID 65976
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Neuro-PS Phosphatidylserine 200 mg by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
766443165392
IngredientAmount% DV
Calories20 Calorie(s)--
Calories from Fat15 Calorie(s)--
Total Fat1.5 Calorie(s)2%
Neuro-PS2000 mg--

Other ingredients: Gelatin, Medium Chain Triglycerides, Vegetable Glycerin, natural Caramel color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Quality Assured

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) softgels daily, preferably with meals.

Brand IP Statement(s)

Neuro-PS is a premier brain supplement derived from natural sources.

Phosphatidylserine levels in the brain can decline with age, so it is important to supplement with Neuro-PS every day to aid brain function and support a healthy mind. When choosing PS, make sure it’s Neuro-PS!

At Vitamin World we ensure the quality of all of our premium nutritional products, every step of the way. Strict quality analysis at world-class facilities guarantees that all Vitamin World products are at the highest standard of potency and purity.

2016 Vitamin World, Inc.

Nutrition from the source

Formula

Each softgel is standardized for the active ingredient Phosphatidylserine (PS), which is non-genetically modified and processed without bacteria to ensure quality, purity and potency.

With even more Phosphatidylserine per softgel

Formulation

No Artificial Flavor or Sweetener, no Preservatives, no Sugar, no Starch, no Milk, no Lactose, no Gluten, no Wheat, no Yeast, no Fish. Sodium free.

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

PROD. #16539 B16538 06E

General Statements

Double strength

Aids brain function, supports a healthy mind and helps replenish PS levels

To reorder prod. #16539 www.vitaminworld.com 1-800-228-4533

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Neuro-PS Phosphatidylserine 200 mg by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Neuro-PS Phosphatidylserine 200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Neuro-PS Phosphatidylserine 200 mg by Vitamin World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Neuro-PS

Interacts with
219 drugs
2000 mg per serving Form: Phosphatidylserine, Soy Lecithin

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Neuro-PS monograph & interactions

Other (inactive) ingredients: Gelatin, Medium Chain Triglycerides, Vegetable Glycerin, Natural Caramel color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Neuro-PS Phosphatidylserine 200 mg by Vitamin World Drug Interactions

Want to check YOUR meds against Neuro-PS Phosphatidylserine 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Neuro-PS 219

Individual Drug Interactions

The ingredients in Neuro-PS Phosphatidylserine 200 mg interact with 219 drugs. Click any drug to see the details.

1 of the 1 ingredient in Neuro-PS Phosphatidylserine 200 mg interact with drugs. Each result below shows which ingredient is responsible. Neuro-PS

Each ingredient & the kinds of drugs it affects

For each ingredient in Neuro-PS Phosphatidylserine 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Neuro-PS2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Neuro-PS full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Neuro-PS Phosphatidylserine 200 mg, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Holbrook
State
NY
ZipCode
11741
Phone Number
1-800-228-4533
Web Address
www.vitaminworld.com
Pharmacist Counseling Corner

Neuro-PS Phosphatidylserine 200 mg by Vitamin World: Common Questions

Does Neuro-PS Phosphatidylserine 200 mg by Vitamin World interact with any medications?
Yes. Based on its ingredients, Neuro-PS Phosphatidylserine 200 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Neuro-PS Phosphatidylserine 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylserine and what does it do in the body?
Phosphatidylserine is a fat-like substance that's a natural part of your cell membranes, especially in your brain. It's thought to support brain function by increasing levels of a chemical messenger called acetylcholine. This product contains 200 mg per capsule.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety information to recommend phosphatidylserine during pregnancy or while breastfeeding. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist before starting this supplement.
Does phosphatidylserine work for memory and focus?
It's possibly effective for age-related memory decline and Alzheimer disease. For other brain uses like ADHD, athletic performance, or general cognitive function, the evidence we have isn't strong enough to say whether it works.
What side effects might I experience?
Most common side effects are flatulence, stomach upset, headache, insomnia, and nausea. Stomach issues can happen at the 200 mg dose in this product. Insomnia is more likely at higher doses. The supplement is generally well tolerated, but long-term safety hasn't been fully studied.
Will this interact with my medications?
Phosphatidylserine has documented interactions with anticholinergic and cholinergic medications (both Moderate severity). Use the interaction checker on this page to search your exact medications before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Neuro-PS Phosphatidylserine 200 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Neuro-PS Phosphatidylserine 200 mg label
Go deeper

The Full Monographs Behind Neuro-PS Phosphatidylserine 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

Neuro-PS Phosphatidylserine 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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