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Dietary supplement

Nicotinamide Pantothenate 675 mg Ingredients & Drug Interactions

by Biophix

Nicotinamide Pantothenate 675 mg label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Nicotinamide Pantothenate 675 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Nicotinamide Pantothenate 675 mg is a dietary supplement by Biophix with 3 active ingredients. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).Based on those ingredients, 287 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium, Nicotinic Amide Niacin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Nicotinamide Pantothenate 675 mg by Biophix

Ask about any prescription or over-the-counter medication and we check it for interactions with Nicotinamide Pantothenate 675 mg by Biophix — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Nicotinamide Pantothenate 675 mg by Biophix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Nicotinamide Pantothenate” is listed as a grouped ingredient — the label gives one combined amount (1,350 mg) without saying how much of each component you get.

This capsule contains three active ingredients. Pantothenic acid (vitamin B5) is included to support normal metabolism and cell function.

Calcium provides a mineral essential for bone health, muscle function, and nerve signaling. Niacinamide, also called nicotinic amide niacin, is a form of vitamin B3 that plays a role in energy production and DNA repair.

The capsule also contains inactive ingredients—cellulose, microcrystalline cellulose, magnesium stearate, and silica—which are fillers and binders that help hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Skin health and healthy oil production.
  • We looked for evidence on: Acne, Aging skin, Atopic dermatitis (eczema), Cheilitis, Dandruff, Dry skin — and 4 related terms.
  • The strongest evidence on file: Niacinamide is rated "Possibly Effective" for Acne (Natural Medicines).
  • Also on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Nonmelanoma skin cancer.
  • Also on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Acne, Atopic dermatitis (eczema), Dry skin, Dandruff, and more.

Pantothenic acid is effective for treating pantothenic acid deficiency, though evidence is insufficient to rate it for allergic rhinitis, alcoholism, or alopecia areata (patchy hair loss). It was found possibly ineffective for radiation dermatitis.

Calcium is effective for kidney failure, upset stomach (dyspepsia), low blood calcium (hypocalcemia), and high potassium (hyperkalemia), and likely effective for osteoporosis. Niacinamide is likely effective for pellagra (a niacin-deficiency disease) and possibly effective for acne, high phosphate levels (hyperphosphatemia), osteoarthritis, and diabetes, though it was found possibly ineffective for brain tumors.

The evidence we hold does not cover whether this combination product as a whole works for any single condition.

The evidence, ingredient by ingredient Pantothenic Acid Calcium Niacinamide

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pantothenic acid is generally well tolerated at typical supplement doses; the main concern with high doses is to check with your doctor first. Calcium is generally safe at recommended amounts, though very high doses may carry theoretical risks (kidney stones, and some research suggests excessive intake might be linked to heart concerns and prostate cancer risk—see adverse effects below).

Niacinamide is usually well tolerated at recommended amounts, but high doses can cause side effects and should be supervised. Common side effects from niacinamide include dizziness, drowsiness, itching, headache, and gastrointestinal upset; topically it may cause burning or mild skin irritation.

Calcium may cause belching, constipation, diarrhea, flatulence, or stomach upset. Pantothenic acid applied to skin has rarely been associated with burning or irritation, and taken by mouth it may cause diarrhea.

Side effects, ingredient by ingredient Pantothenic Acid Calcium Niacinamide

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Calcium, Niacinamide.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
  • For scale: 287 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any HIV medications (dolutegravir, elvitegravir, raltegravir), the antibiotic ceftriaxone, blood thinners or antiplatelet drugs (warfarin especially), thyroid medication levothyroxine, heart drugs like diltiazem or sotalol, seizure medications (carbamazepine, primidone), or the psoriasis drug calcipotriene. The calcium in this product is the main driver of these interactions and may reduce the effectiveness of several of these drugs or cause harmful drug levels.

Space dosing carefully—usually 2 to 6 hours apart, depending on the medication—or your doctor may need to adjust your prescription dose.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This three-ingredient supplement is mainly useful for pantothenic acid deficiency, general bone and mineral support, or B vitamin intake—but the calcium and niacinamide carry significant medication interactions you need to check first, especially if you take HIV drugs, blood thinners, heart medications, or thyroid medication. If you take any prescription drugs, use the interaction checker on this page with each medication name, and then talk with your pharmacist or doctor before starting.

Those on a typical diet usually get enough of these nutrients from food alone.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Nicotinamide Pantothenate 675 mg, straight from the product label.

Brand Biophix
Barcode (UPC) X001YVJM77
Net contents 120 Veg Cap(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276054
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Nicotinamide Pantothenate 675 mg by Biophix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
X001YVJM77
IngredientAmount% DV
Pantothenic Acid1100 mg22000%
Calcium99 mg7%
Nicotinic Amide Niacin250 mg1562%
Nicotinamide Pantothenate1350 mg--

Other ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, take 2 capsules twice daily, preferably with meals.

Formula

Biophix Nicotinamide Pantothenate is a scientifically engineered molecular complex formula consisting of pantothenic-acid-bound nicotinic amide niacin. Developed for dermatologists, nicotinamide pantothenate supports healthy oil skin production and natural, smooth, and clear skin.

Pantothenic acid bound nicotinic amide niacin

Precautions

Caution: For adults only.

Not to be used by pregnant/ lactating women or those with liver problems, stomach ulcers, or diabetes unless recommended by your healthcare practitioner.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Manufactured in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool, dry place after opening.

General Statements

Please recycle.

Formulation

Natural color variation may occur in this product.

Clear Skin Series

Supports healthy skin oil production Supports clear & smooth skin

Vegan

GMP tested

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.

Gluten free GMO free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Manufactured in a GMP Inspected Facility

Made in USA

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Nicotinamide Pantothenate 675 mg by Biophix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Nicotinamide Pantothenate 675 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Nicotinamide Pantothenate 675 mg by Biophix

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Nicotinamide Pantothenate

1350 mg per serving

Other (inactive) ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Nicotinamide Pantothenate 675 mg by Biophix Drug Interactions

Want to check YOUR meds against Nicotinamide Pantothenate 675 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
287Drugs
7 Major 262 Moderate 18 Minor

Ingredients driving the most interactions

Calcium 168
Nicotinic Amide Niacin 124

Individual Drug Interactions

The ingredients in Nicotinamide Pantothenate 675 mg interact with 287 drugs. Click any drug to see the details.

2 of the 3 ingredients in Nicotinamide Pantothenate 675 mg interact with drugs. Each result below shows which ingredient is responsible. Calcium Nicotinic Amide Niacin

Each ingredient & the kinds of drugs it affects

For each ingredient in Nicotinamide Pantothenate 675 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

Nicotinic Amide Niacin4 drug types · 124 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, niacinamide may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on hemodialysis.
Several cases of thrombocytopenia have been reported for hemodialysis patients treated with niacinamide 1 gram daily. Hemodialysis patients receiving niacinamide had almost a three-fold higher risk of developing thrombocytopenia when compared with those receiving placebo.

Likelihood Unlikely Evidence D
Carbamazepine (Tegretol)

Niacinamide might increase the levels and adverse effects of carbamazepine.
Plasma levels of carbamazepine were increased in two children given high-dose niacinamide, 60-80 mg/kg/day. This might be due to inhibition of the cytochrome P450 enzymes involved in carbamazepine metabolism. There is not enough data to determine the clinical significance of this interaction.

Likelihood Possible Evidence D
Primidone (Mysoline)

Niacinamide might increase the levels and adverse effects of primidone.
Case reports in children suggest niacinamide 60-100 mg/kg/day reduces hepatic metabolism of primidone to phenobarbital, and reduces the overall clearance rate of primidone; however, there is not enough data to determine the clinical significance of this potential interaction.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that niacinamide may increase the anticoagulant effects of warfarin.
In a case report, a patient on warfarin developed an elevated international normalized ratio (INR) of 8.4 after taking niacinamide 500 mg twice daily for 10 days. The patient's INR was previously stable, ranging between 2 and 3, with no other changes to current medications or diet reported. The elevated INR returned to the therapeutic range after receiving vitamin K and discontinuing niacinamide.

Likelihood Possible Evidence D
Nicotinic Amide Niacin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Nicotinamide Pantothenate 675 mg, from the product label.

Biophix

See all Biophix products
Name
Biophix Health & Nutrition
Street Address
4131 SW 47th Ave. Unit 1404
City
Davie
State
FL
ZipCode
33314
Phone Number
305-861-0898
Web Address
www.biophix.com
Pharmacist Counseling Corner

Nicotinamide Pantothenate 675 mg by Biophix: Common Questions

Does Nicotinamide Pantothenate 675 mg by Biophix interact with any medications?
Yes. Based on its ingredients, Nicotinamide Pantothenate 675 mg has a known interaction with 287 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Nicotinamide Pantothenate 675 mg contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pantothenic acid, and what does it do?
Pantothenic acid is vitamin B5, a nutrient involved in energy production and metabolism throughout your body. It's effective for treating pantothenic acid deficiency but doesn't have enough evidence to support use for hay fever, hair loss, or alcoholism.
Can I take this if I have thyroid disease and take levothyroxine?
Calcium in this product can reduce how much levothyroxine your body absorbs, making it less effective for your thyroid. You'd need to take them at least 4 hours apart. Talk with your pharmacist or doctor about the right timing or whether this product makes sense for you.
Is niacinamide the same as niacin?
Niacinamide (also called nicotinic amide niacin) is a form of vitamin B3, different from regular niacin. It's likely effective for pellagra and possibly effective for acne, arthritis, and diabetes. At high doses it can cause dizziness, drowsiness, and stomach upset.
Will this product help my bones?
Calcium in this product is likely effective for osteoporosis prevention and bone health. However, make sure the dose doesn't exceed recommended daily amounts (especially if you're also getting calcium from food or other supplements), and talk with your doctor about whether supplementing makes sense for you personally.
Are there fillers or other ingredients I should know about?
Yes, this capsule contains inactive ingredients: cellulose, microcrystalline cellulose, magnesium stearate, and silica. These are standard binders and fillers used to hold the capsule together.
Is this safe if I'm pregnant or breastfeeding?
All three active ingredients—pantothenic acid, calcium, and niacinamide—are rated likely safe during pregnancy and breastfeeding at normal amounts. Amounts in food and standard prenatal vitamins are fine, but if you're considering a supplement, check with your doctor or pharmacist for personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Nicotinamide Pantothenate 675 mg label
Go deeper

The Full Monographs Behind Nicotinamide Pantothenate 675 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Niacinamide

Interacts with 124 drugs

Niacinamide (also called nicotinamide) is a form of vitamin B3 used in supplements and skin-care products. It is well established for preventing and treating vitamin B3 deficiency, and there...

Read the full Niacinamide monograph →
Sources

Sources & How We Checked

Nicotinamide Pantothenate 675 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 95 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pantothenic Acid 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
  5. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
  6. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
  7. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  8. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
  9. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
  10. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
  11. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed

See these in context on the Pantothenic Acid monograph →

Calcium 62 references
  1. Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
  2. Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
  3. Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
  4. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  5. Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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