Nine Flavor Tea Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Nine Flavor Tea against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Nine Flavor Tea is a dietary supplement by Health Concerns with 9 active ingredients. Its ingredients are commonly taken for menstrual cramps and irregular periods, muscle cramps and spasms, anxiety and stress.Based on those ingredients, 1,255 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Moutan, Poria sclerotium, Rehmannia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Nine Flavor Tea by Health Concerns
Ask about any prescription or over-the-counter medication and we check it for interactions with Nine Flavor Tea by Health Concerns — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Nine Flavor Tea by Health Concerns
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Nine Flavor Tea contains 9 active ingredients delivered in tablet or pill form. The formula combines moutan (peony), dioscorea, alisma, cornus (American dogwood), poria mushroom, ophiopogon, rehmannia, glehnia, and schrophularia (figwort) — a blend rooted in traditional Chinese herbal practice.
These are delivered alongside inactive ingredients including vegetable gum, silicon dioxide, stearic acid, and cellulose.
Does it work?
Moderate evidence
The evidence backing this formula is limited. Rehmannia is possibly effective for chronic kidney disease; the other ingredients have insufficient reliable evidence to establish their effectiveness for the conditions listed — aging skin, anal fissures, atherosclerosis, chronic fatigue, cirrhosis, and migraine headache are all rated as lacking adequate research in our data.
How safe is it?
Well-documented data
Moutan (peony) is generally well tolerated for short-term use, though high-quality safety data are limited. Common side effects include gastrointestinal discomfort — stomach bloating, loss of appetite, diarrhea, and nausea — with diarrhea reported in about 5% of people taking higher doses in trials.
Skin irritation can occur with topical use. There is a rare case report of bleeding complications when peony-containing products were used alongside warfarin.
Poria mushroom is generally well tolerated but allergic reactions (allergic rhinitis or asthma) have been reported rarely. Cornus, rehmannia, and figwort have very limited human safety data.
Pregnancy: the safety data advise against moutan, poria mushroom, cornus, rehmannia, and figwort during pregnancy — avoid all five. Breastfeeding: the same ingredients lack reliable safety data while breastfeeding, so avoidance is advised for each.
Meds to double-check
Moderate interaction found
Before taking Nine Flavor Tea, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (bleeding risk is Moderate), birth control or hormone therapy (interference risk is Moderate), psychiatric or seizure medications like clozapine or phenytoin (effectiveness risk is Moderate), sedatives or sleep aids (enhancement risk is Moderate), blood pressure medications (low blood pressure risk is Moderate), diabetes medications (low blood sugar risk is Moderate), water pills or lithium (interaction risk is Moderate), or drugs affecting acetylcholine pathways. No interactions are documented for dioscorea, alisma, or ophiopogon — those ingredients were not checked.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This traditional herbal formula is best suited for someone already familiar with Chinese medicine and working with a practitioner or healthcare provider who knows their full medication list. Anyone taking blood thinners, psychiatric medications, birth control, blood pressure or diabetes drugs, diuretics, lithium, or acetylcholine-related medications should discuss this product with their own doctor or pharmacist before starting.
Pregnant and breastfeeding individuals should avoid it entirely. Check your exact medications using the search tool on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Nine Flavor Tea, straight from the product label.
| Brand | Health Concerns |
|---|---|
| Net contents | 270 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2017 |
| DSLD ID | 73088 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Nine Flavor Tea by Health Concerns, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 750 mg | -- |
| Moutan | 0 NP | -- |
| Dioscorea | 0 NP | -- |
| Alisma | 0 NP | -- |
| Cornus | 0 NP | -- |
| Poria sclerotium | 0 NP | -- |
| Ophiopogon | 0 NP | -- |
| Rehmannia | 0 NP | -- |
| Glehnia | 0 NP | -- |
| Schrophularia | 0 NP | -- |
Other ingredients: Vegetable Gum, Silicon Dioxide, Stearic Acid, Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Three tablets 3 times per day between meals.
Precautions
Notice: This product is not intended for use by pregnant women.
General Statements
Made in the U.S.A.
Modified Liu Wei Di Huang
Brand IP Statement(s)
Chinese traditional formulas
Combining modern research and ancient wisdom
FDA Statement of Identity
Herbal Supplement
Formula
Pinyin: Sheng Di Huang, Shan Yao, Fu Ling, Shan Zhu Yu, Mu Dan Pi, Ze Xie, Xuan Shen, Sha Shen, Mai Men Dong.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Nine Flavor Tea by Health Concerns label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Nine Flavor Tea by Health Concerns
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Moutan
- › Dioscorea
- › Alisma
- › Cornus
- › Poria sclerotium
- › Ophiopogon
- › Rehmannia
- › Glehnia
- › Schrophularia
Other (inactive) ingredients: Vegetable Gum, Silicon Dioxide, Stearic Acid, Cellulose. These complete the product’s ingredient list but are not active constituents.
Nine Flavor Tea by Health Concerns Drug Interactions
HelloPharmacist Interaction Report
Nine Flavor Tea by Health Concerns contains several ingredients with documented drug interactions.
Through its moutan (peony), poria mushroom, rehmannia, and figwort content, this product may interact with medications — most seriously with blood thinners (anticoagulants or antiplatelet drugs), where peony theoretically increases bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Peony also affects how your body metabolizes certain psychiatric and seizure medications (clozapine and phenytoin), and may interfere with hormone-related drugs including birth control pills and hormone replacement therapy through its estrogenic activity. Poria mushroom may enhance sedatives and affect drugs that work through acetylcholine pathways (anticholinergic and cholinergic medications).
Rehmannia theoretically raises the risk of dangerously low blood pressure (hypotension) or blood sugar (hypoglycemia) when combined with blood pressure or diabetes medications. Figwort may interact with water pills (diuretics) by worsening potassium loss, and theoretically could raise lithium levels.
We could not check three other ingredients — Dioscorea, Alisma, and Ophiopogon — because interaction data are not on file for them. Altogether, these interactions span 1,256 individual medications.
Use the search tool below to check your specific prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Nine Flavor Tea?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Nine Flavor Tea interact with 1,255 drugs. Click any drug to see the details.
4 of the 9 ingredients in Nine Flavor Tea interact with drugs. Each result below shows which ingredient is responsible. Moutan Poria sclerotium Rehmannia Schrophularia
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Moutan + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Moutan + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
RehmanniaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Rehmannia + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
RehmanniaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Rehmannia + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Moutan + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
Poria SclerotiumCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Moutan + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acetaminophen, Butalbital, Caffeine, Codeine interactionPoria SclerotiumCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Butalbital, Codeine interactionPoria SclerotiumCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
Poria SclerotiumCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Butalbital, Codeine Phosphate interactionMoutanCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPoria SclerotiumAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
Poria SclerotiumCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Caffeine, Codeine interactionMoutanCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPoria SclerotiumCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
Poria SclerotiumCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Caffeine, Dihydrocodeine interactionMoutanCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Nine Flavor Tea — through 1 ingredient. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Nine Flavor Tea — through 3 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acetaminophen, Caffeine, Pyrilamine interactionPoria SclerotiumAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium + Acetaminophen, Caffeine, Pyrilamine interactionSchrophulariaDiuretic Drugs Moderate
Interaction Summary
Theoretically, overuse of figwort might compound diuretic-induced potassium loss.
Read the full Schrophularia + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
Poria SclerotiumAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionMoutanCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPoria SclerotiumCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Sclerotium + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
MoutanCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Moutan + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPoria SclerotiumAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Nine Flavor Tea — through 2 ingredients. Tap an ingredient for the detail:
Poria SclerotiumAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Sclerotium + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionMoutanCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Moutan + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Nine Flavor Tea with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Moutan
Anticoagulant/Antiplatelet Drugs
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.
Clozapine (Clozaril)
Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.
Contraceptive Drugs
Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.
Phenytoin (Dilantin)
Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.
Poria sclerotium
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Rehmannia
Antidiabetes Drugs
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.
Antihypertensive Drugs
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).
Schrophularia
Diuretic Drugs
Theoretically, overuse of figwort might compound diuretic-induced potassium loss. There is some concern that people taking figwort along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
Lithium
Figwort is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, figwort might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Nine Flavor Tea, from the product label.
Health Concerns
See all Health Concerns products- Name
- Health Concerns
- Street Address
- 8001 Capwell Drive
- City
- Oakland
- State
- CA
- ZipCode
- 94621
- Phone Number
- (800) 233-9355
- Web Address
- www.healthconcerns.com/pro
Nine Flavor Tea by Health Concerns: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Nine Flavor Tea’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Peony
Interacts with 811 drugsPeony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formulas. Human evidence for most uses is lim...
Read the full Peony monograph → Herb & supplement monographAmerican Dogwood
American Dogwood is a North American flowering tree whose bark was used in traditional folk medicine, especially as a substitute for quinine to treat fevers. There is very little modern huma...
Read the full American Dogwood monograph → Herb & supplement monographPoria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph → Herb & supplement monographRehmannia
Interacts with 258 drugsRehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...
Read the full Rehmannia monograph → Herb & supplement monographFigwort
Interacts with 76 drugsFigwort is a traditional herb used mainly for skin problems and minor swelling, but solid human studies are lacking, so its benefits remain unproven. It is generally used short-term and topi...
Read the full Figwort monograph →Sources & How We Checked
Nine Flavor Tea's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Peony 15 references
- Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
- Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
- Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
- Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
- Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
- Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
- Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
- Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
- Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
- Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
- Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
- Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
- Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
- Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
- Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i
American Dogwood 1 reference
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
Poria Mushroom 3 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
- Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.
Rehmannia 3 references
- Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
- Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
- Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.
Figwort 1 reference
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC