Interactions on record — worth a quick check against your medications. Based on 4 of 5 ingredients. Check your meds →
Dietary supplement

NovaPump Blueberry Lemonade Ingredients & Drug Interactions

by InnovaPharm

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

NovaPump Blueberry Lemonade is a dietary supplement by InnovaPharm with 5 active ingredients. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 510 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are PegaPump, Agmatine Sulfate, Super Spinach. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of NovaPump Blueberry Lemonade by InnovaPharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

NovaPump has five active ingredients. Citrulline malate and agmatine sulfate are amino acid compounds often used in workout supplements to support blood flow.

GlycerPump (glycerol) is a humectant and osmotic agent—it draws water into tissues and is sometimes used to boost athletic endurance. Super Spinach is a whole-food concentrate bringing in the nutrients and compounds spinach naturally contains.

PegaPump (rue) is a dried herb traditionally used in supplements, though its effects are not well established. The product also contains inactive ingredients: natural and artificial flavor, silica (a flow agent), citric acid, sucralose, and acesulfame potassium (sweeteners).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: nitric oxide amplifier for exercise performance.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise endurance, Workout capacity, Blood flow, Vasodilation.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Spinach is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.
  • Also on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Muscle strength.

The evidence on these ingredients is sparse. Glycerol is likely effective for constipation and possibly effective for athletic performance, though the data on athletic benefit is limited.

For spinach, agmatine, rue, and citrulline malate, the evidence we hold does not establish effectiveness for any specific purpose—the ratings across these ingredients range from insufficient evidence to rate them to insufficient reliable evidence. If you're considering this product for a particular goal, check with your pharmacist about what the research actually shows for that use.

The evidence, ingredient by ingredient Agmatine Glycerol Spinach Rue

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of agmatine appears generally well tolerated, but long-term safety in humans isn't well studied. Orally, it can cause diarrhea, indigestion, and nausea—mild-to-moderate diarrhea and nausea appeared in a small number of trial participants within a few days and resolved when they stopped.

Glycerol is generally well tolerated in normal amounts but can cause bloating, nausea, vomiting, dizziness, and headache in larger doses. Spinach as a food is considered safe for most people and safe during pregnancy and breastfeeding.

Rue, however, is concerning: it can be toxic in higher doses, the fresh form is unsafe, and the dried herb can cause cramps, drowsiness, dizziness, and gastrointestinal irritation. Most importantly, rue should be avoided during pregnancy and breastfeeding due to safety concerns.

Side effects, ingredient by ingredient Agmatine Glycerol Spinach Rue

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Spinach, Rue, Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 510 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check these medication types before taking NovaPump: photosensitizing drugs (skin medications), antihypertensive drugs (blood pressure medications), antidiabetes drugs (diabetes medications), and warfarin or other blood thinners (anticoagulants). If any of your prescriptions fall into these categories, use the medication checker on this page to see if there's a documented interaction.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product mixes workout-support ingredients with herbs that carry real interaction risks—especially if you take blood pressure meds, diabetes meds, blood thinners, or photosensitizing drugs. Pregnancy and breastfeeding are reasons to avoid it because of rue.

Before you start, check your exact medications against our tool and talk with your pharmacist about whether this product fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NovaPump Blueberry Lemonade, straight from the product label.

Brand InnovaPharm
Net contents 0.56 Ounce(s); 16 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 299178
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NovaPump Blueberry Lemonade by InnovaPharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
16 Gram(s)
Maximum serving Sizes:
16 Gram(s)
Servings per container
1
IngredientAmount% DV
Citrulline Malate8 Gram(s)--
Agmatine Sulfate1 Gram(s)--
GlycerPump4 Gram(s)--
Super Spinach1 Gram(s)--
PegaPump250 mcg--

Other ingredients: Natural and Artificial flavor, Silica, Citric Acid, Sucralose, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Massively dosed nitric oxide amplifier

8G Citrulline 1G Agmatine 1G Super Spinach 4G Glycer Pump 250MCG Pega Pump

Blueberry Lemonade Naturally & Artificially Flavored

Formulation

Stim Free

No Artificial Colors or Dyes

Allergen Information: Not manufactured with wheat, gluten, soy, fish, shellfish, egg, milk or tree nut ingredients.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Consume 1 packet mixed with 10-16 oz of water approximately 15-30 minutes before exercise. For best results, use daily on an empty stomach.

General Statements

Twitter Instagram Facebook @InnovaPharm InnovaPharm.com

Precautions

WARNING: This product is only intended to be consumed by adults.

18 Years of age or older.

Do not use if you are pregnant or nursing. Do not use this product if you have any serious medical conditions. Before using this product, consult with a licensed, qualified, health care professional, including but not limited to, if you suspect you have or have been treated for, diagnosed with or have a family history of any medical condition, or if you are using any prescription or over the counter medication.

Immediately discontinue use and contact a medical doctor if you experience any adverse reaction to this product. Discontinue use 2 weeks prior to surgery. Do not use if packet is torn or damaged.

Keep out of reach of children.

Allergen Information: Not manufactured with wheat, gluten, soy, fish, shellfish, egg, milk or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

NovaPump Blueberry Lemonade by InnovaPharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in NovaPump Blueberry Lemonade by InnovaPharm

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size16 Gram(s) Dosage formPowder Servings per container1 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Citrulline Malate

8 Gram(s) per serving

Agmatine Sulfate

Interacts with
258 drugs
1 Gram(s) per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions

GlycerPump

No known
interactions
4 Gram(s) per serving Form: Glycerol, Powder

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...

GlycerPump monograph & interactions

Super Spinach

Interacts with
88 drugs
1 Gram(s) per serving Form: Red Spinach Leaf Extract

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is...

Super Spinach monograph & interactions

PegaPump

Interacts with
335 drugs
250 mcg per serving Form: Peganum harmala L. Extract

Rue is a strong-smelling herb from southern Europe with a long history in folk medicine, but there is very little reliable human research to support i...

PegaPump monograph & interactions

Other (inactive) ingredients: Natural and Artificial flavor, Silica, Citric Acid, Sucralose, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

NovaPump Blueberry Lemonade by InnovaPharm Drug Interactions

Want to check YOUR meds against NovaPump Blueberry Lemonade?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
510Drugs
510 Moderate

Ingredients driving the most interactions

PegaPump 335

Each ingredient & the kinds of drugs it affects

For each ingredient in NovaPump Blueberry Lemonade with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

PegaPump1 drug type · 335 drugs

Photosensitizing Drugs

Theoretically, rue might increase the risk for phototoxicity when used with photosensitizing drugs.
Rue contains photosensitizing furanocoumarins and psoralens and has been associated with multiple reports of phototoxic reactions. There is also one case report of an increased phototoxic response to psoralen and ultraviolet A (PUVA) therapy associated with ingestion of rue.

Likelihood Possible Evidence D

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D

Super Spinach2 drug types · 88 drugs

Antidiabetes Drugs

There are claims that spinach leaves have hypoglycemic effects. Evidence from clinical research suggests that consumption of a spinach-rich meal reduces post-meal blood glucose levels. Theoretically, spinach might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Spinach contains vitamin K, which can interfere with the activity of warfarin.
In human research, although eating spinach with one meal does not result in coagulation test results outside the therapeutic range, daily consumption for one week necessitates dose adjustment of warfarin. Individuals using anticoagulants should consume a consistent daily amount of spinach to maintain the effect of anticoagulant therapy.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for NovaPump Blueberry Lemonade, from the product label.

InnovaPharm

See all InnovaPharm products
Name
InnovaPharm
Street Address
53 East Merrick Rd. #215
City
Freeport
State
NY
ZipCode
11520
Web Address
InnovaPharm.com
Pharmacist Counseling Corner

NovaPump Blueberry Lemonade by InnovaPharm: Common Questions

Does NovaPump Blueberry Lemonade by InnovaPharm interact with any medications?
Yes. Based on its ingredients, NovaPump Blueberry Lemonade has a known interaction with 510 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NovaPump Blueberry Lemonade contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. Rue (PegaPump) should be avoided during pregnancy because it may harm a pregnancy and has traditionally been used to bring on miscarriage, so there isn't enough safety data. During breastfeeding, rue is also not recommended because potentially toxic compounds may pass to the baby. Agmatine and glycerol also lack enough safety data in pregnancy and lactation. Talk with your doctor about whether this product is right for you.
What's the most common side effect I might notice?
Agmatine and glycerol can both cause digestive upset—diarrhea, nausea, indigestion, and bloating. These are generally mild and may appear within a few days of starting. Rue can cause dizziness, drowsiness, and gastrointestinal irritation. If you experience side effects that don't go away, stop and ask your pharmacist.
Will this help my athletic performance?
Glycerol is possibly effective for athletic performance, though the evidence is limited. For the other active ingredients—agmatine, citrulline malate, spinach, and rue—we don't have established evidence that they improve athletic performance in our data. Your results may vary, but the science backing this product for that purpose is thin.
Is rue safe to use long-term?
No. Rue can be toxic in higher doses and is not well studied for safety. The fresh form is considered unsafe. The dried herb can cause cramps, dizziness, drowsiness, and gastrointestinal irritation. Use it cautiously if at all, and never long-term without talking to your doctor.
What if I take warfarin or another blood thinner?
Spinach (Super Spinach) contains vitamin K, which interferes with warfarin and other blood thinners. Even though a single meal with spinach won't throw off your test results, daily consumption for a week can require a dose adjustment. If you take a blood thinner, keep your spinach intake consistent and let your pharmacist know before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NovaPump Blueberry Lemonade is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NovaPump Blueberry Lemonade label
Sources

Sources & How We Checked

NovaPump Blueberry Lemonade's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Spinach 6 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Karlson, B., Leijd, B., and Hellstrom, K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand. 1986;220(4):347-350. PubMed
  3. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
  4. Schuller, A., Morisset, M., Maadi, F., Kolopp Sarda, M. N., Fremont, S., Parisot, L., Kanny, G., and Moneret-Vautrin, D. A. Occupational asthma due to allergy to spinach powder in a pasta factory. Allergy 2005;60(3):408-409. PubMed
  5. Gustafsson, K., Asp, N. G., Hagander, B., and Nyman, M. Satiety effects of spinach in mixed meals: comparison with other vegetables. Int.J.Food Sci.Nutr. 1995;46(4):327-334. PubMed
  6. Schreiber, J., Muller, E., Becker, W. M., Zabel, P., Schlaak, M., and Amthor, M. [Spinach powder-induced exogenous allergic alveolitis]. Pneumologie 1998;52(1):61-65.

See these in context on the Spinach monograph →

Rue 8 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  6. Puig L. Pharmacodynamic interaction with phototoxic plants during PUVA therapy. Br J Dermatol 1997;136:973-4. PubMed
  7. Radotra I, Gardiner S, Barnes D. A phytophototoxic injury at a burns unit: the ungraceful after-effects of the "common rue" plant. J Burn Care Res. 2018;39(6):1064-6. PubMed
  8. Avallone G, Mastorino L, Agostini A, et al. Ruta graveolens phytophotodermatitis. Dermatol Online J 2021;27(7). PubMed

See these in context on the Rue monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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