Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Omega-3 Krill Oil 350 mg Ingredients & Drug Interactions

by Schiff MegaRed

Omega-3 Krill Oil 350 mg label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Omega-3 Krill Oil 350 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Omega-3 Krill Oil 350 mg is a dietary supplement by Schiff MegaRed with 4 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, high triglycerides, joint pain and inflammation.Based on those ingredients, 976 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, Omega-3 Fatty Acids, Krill Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Omega-3 Krill Oil 350 mg by Schiff MegaRed

Ask about any prescription or over-the-counter medication and we check it for interactions with Omega-3 Krill Oil 350 mg by Schiff MegaRed — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Omega-3 Krill Oil 350 mg by Schiff MegaRed

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (90 mg) without saying how much of each component you get.

This softgel contains 5 ingredients. The active components are krill oil—a marine source of omega-3 fatty acids—along with eicosapentaenoic acid and docosahexaenoic acid (two specific omega-3s), phospholipids (fat compounds), and astaxanthin (a natural carotenoid pigment).

The inactive ingredients are gelatin, glycerin, water, ethyl vanillin, and sorbitol, which form the capsule and keep the contents stable.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

  • Dry eye via Krill Oil Possibly Effective
Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Dry eye — rated "Possibly Effective" (Krill Oil) (Natural Medicines).

Krill oil is rated possibly effective for dry eye. For other uses—aging skin, Alzheimer disease, cancer, high cholesterol (hyperlipidemia), and cognitive function—the evidence we hold is insufficient to rate it.

Astaxanthin similarly lacks established evidence for age-related cognitive decline, age-related macular degeneration, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome. If you're considering this product for a specific health goal, talk it over with your doctor or pharmacist about what the research actually shows.

The evidence, ingredient by ingredient Krill Oil Docosahexaenoic Acid (dha) Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Krill oil is generally well tolerated up to 4 grams daily. The most common side effects are mild digestive ones: bloating, decreased appetite, diarrhea, fishy burps, flatulence, heartburn, nausea, and stomach discomfort.

Headache, tiredness, and dizziness have been reported rarely. Avoid krill oil if you have a shellfish allergy and use caution if you have a bleeding disorder.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited; the most common side effects in studies were abdominal pain, diarrhea, and red-colored stools. For pregnancy and breastfeeding, the safety data aren't established for either ingredient—talk with your doctor or pharmacist before using during pregnancy or while nursing.

Side effects, ingredient by ingredient Krill Oil Docosahexaenoic Acid (dha) Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Astaxanthin, Krill Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 839 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on blood thinners or antiplatelet drugs—krill oil may raise bleeding risk (Moderate severity). Also confirm if you take diabetes medications, since krill oil may theoretically lower blood sugar further.

If you take drugs that your liver breaks down via CYP3A4 or CYP2B6 pathways—including many statins and blood pressure medications—astaxanthin may theoretically lower their levels, though this hasn't been proven in people.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This krill oil supplement may help with dry eye based on current evidence, though other common uses lack solid proof. The main concern is interactions with blood thinners, antiplatelet drugs, diabetes medications, and certain liver-metabolized drugs.

If you take any prescription medications—especially for blood clotting, blood sugar, cholesterol, or blood pressure—check with your doctor or pharmacist before starting. Most people tolerate it well, though digestive side effects like fishy burps and stomach discomfort are common.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Omega-3 Krill Oil 350 mg, straight from the product label.

Brand Schiff MegaRed
Barcode (UPC) 020525104960
Net contents 15 Softgel(s)
Market status On market
Date entered into DSLD Oct 22, 2016
DSLD ID 65454
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Qualified Health, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Omega-3 Krill Oil 350 mg by Schiff MegaRed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
020525104960
IngredientAmount% DV
Krill Oil350 mg--
Omega-3 Fatty Acids90 mg--
Eicosapentaenoic Acid50 mg--
Docosahexaenoic Acid24 mg--
Cholesterol5 mg1%
Phospholipids130 mg--
Astaxanthin17 mcg--

Other ingredients: Gelatin, Glycerin, Water, Ethyl Vanillin, Sorbitol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Actual bottle size

Eco-Friendly. Krill is one of earth’s most abundant and sustainable organisms. The harvest of krill is well below conservative international catch guidelines.

This product comes from a fishery that has been independently certified to the MSC’s standard for a well-managed and sustainable fishery. www.msc.org

GUARANTEED for purity, freshness and labeled potency.

Compare to fish oil

One Small Pill, No Fishy Aftertaste

Actual size

Heart health

Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.

Gelatin is derived from bovine sources.

May reduce the risk of coronary heart disease SUPPORTIVE, BUT NOT CONCLUSIVE RESEARCH SHOWS THAT CONSUMPTION OF EPA AND DHA OMEGA-3 FATTY ACIDS MAY REDUCE THE RISK OF CORONARY HEART DISEASE.

Compare to fish oil MegaRed softgel Fish Oil softgel 100% pure Antarctic Krill oil check Contains Omega-3 Fatty acids check check Just one small softgel per day check No fishy aftertaste check In phospholipid form for easy absorption check Contains powerful antioxidant astaxanthin check

In order for Omega-3s to be put to good use, they must first be absorbed by your body. Traditional fish oil floats on top of your stomach, giving that unpleasant fishy aftertaste.

ITS OMEGA-3s ARE CARRIED IN PHOSPHOLIPID FORM, SO IT: ~ Easily mixes in the stomach and doesn’t leave an unpleasant aftertaste. ~ Is easily recognized and utilized by your body’s cell membranes, which are also phospholipid, allowing easy absorption.

Supportive, but not conclusive research shows that consumption of EPA and DHA Omega-3 fatty acids may reduce the risk of coronary heart disease.

rb Health Hygiene Home

Since 1936

Brand IP Statement(s)

MegaRed goes a step further by only sourcing krill from the Antarctic where krill is most abundant. This helps the ecosystem maintain a healthy, sustainable krill population.

Schiff SURE DISSOLVE softgels are formulated to disintegrate within one hour. Superba is a registered trademark of the Aker Group.

2015 RB

MEGARED OMEGA-3 KRILL OIL IS DIFFERENT.

Just one small pill with no fishy aftertaste, that’s why MegaRed Omega-3 Krill Oil is the superior choice.

Seals/Symbols

C-SCS-0123 Certified sustainable seafood MSC www.msc.org

Schiff Quality Guarantee

Formulation

GUARANTEED: No added sugar (sucrose, fructose, lactose), salt (sodium chloride), yeast, wheat, gluten or milk. No preservatives or artificial colors.

Formula

100% Pure High Absorption Krill Oil

Contains shellfish (krill).

MegaRed contains oil from 100% pure Antarctic krill, tiny crustaceans that thrive in the frigid waters of the Antarctic. Just one small MegaRed softgel provides an optimal combination of omega-3 fatty acids and the powerful antioxidant astaxanthin to support heart health. Research has shown that omega-3s may reduce the risk of coronary heart disease.

With Phospholipid Omega-3s for easy absorption

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) softgel daily.

Precautions

Contains shellfish (krill).

WARNING: People with shellfish allergy, coagulopathy or taking anticoagulants or other medications should notify their physician and be tested prior to taking dietary supplements.

WARNING: People with shellfish allergy, coagulopathy or taking anticoagulants or other medications should notify their physician and be tested prior to taking dietary supplements. If pregnant, breastfeeding or on prescribed medication, consult your physician before using this product.

Keep out of reach of children.

Storage

Store in a cool, dry place with lid tightly closed.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

062215 8219675

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Omega-3 Krill Oil 350 mg by Schiff MegaRed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Omega-3 Krill Oil 350 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Omega-3 Krill Oil 350 mg by Schiff MegaRed

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Krill Oil

Interacts with
208 drugs
350 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

Krill Oil monograph & interactions

Omega-3 Fatty Acids

Interacts with
375 drugs
90 mg per serving

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...

Omega-3 Fatty Acids monograph & interactions
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid

Phospholipids

130 mg per serving

Astaxanthin

Interacts with
671 drugs
17 mcg per serving Form: Krill Oil

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Ethyl Vanillin, Sorbitol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Omega-3 Krill Oil 350 mg by Schiff MegaRed Drug Interactions

Want to check YOUR meds against Omega-3 Krill Oil 350 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
976Drugs
976 Moderate

Ingredients driving the most interactions

Astaxanthin 671
Omega-3 Fatty Acids 375
Krill Oil 208

Individual Drug Interactions

The ingredients in Omega-3 Krill Oil 350 mg interact with 976 drugs. Click any drug to see the details.

3 of the 4 ingredients in Omega-3 Krill Oil 350 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin Omega-3 Fatty Acids Krill Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Omega-3 Krill Oil 350 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions

Omega-3 Fatty Acids3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.

Likelihood Probable Evidence B
Omega-3 Fatty Acids full monograph & interactions

Krill Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Krill Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Omega-3 Krill Oil 350 mg, from the product label.

Schiff MegaRed

See all Schiff MegaRed products
Name
Reckitt Benckiser
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.megared.com
Pharmacist Counseling Corner

Omega-3 Krill Oil 350 mg by Schiff MegaRed: Common Questions

Does Omega-3 Krill Oil 350 mg by Schiff MegaRed interact with any medications?
Yes. Based on its ingredients, Omega-3 Krill Oil 350 mg has a known interaction with 976 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Omega-3 Krill Oil 350 mg contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me fishy burps?
Fishy burps are one of the most common side effects, along with other digestive effects like bloating, heartburn, and diarrhea. The good news is these tend to be less frequent or severe with krill oil compared to regular fish oil, but they can still happen.
Can I take this if I have a shellfish allergy?
No—krill is a shellfish-like crustacean, so you should avoid this product if you have a shellfish allergy.
Is this safe during pregnancy?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist before using it while pregnant—they can help you weigh the pros and cons for your situation.
What is astaxanthin in this product for?
Astaxanthin is a natural pigment added to krill oil supplements. While it's been studied for things like aging skin and eye health, the evidence we hold rates it as insufficient to recommend it for those purposes right now.
How much krill oil is in each softgel?
Each softgel contains 350 mg of krill oil.
Can I take this with my blood pressure medication?
That depends on which one you take. The astaxanthin in this product may theoretically affect how your liver processes certain blood pressure drugs, though this hasn't been confirmed in people. Check the specific names of your medications with the search tool on this page, or ask your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Omega-3 Krill Oil 350 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Omega-3 Krill Oil 350 mg label
Go deeper

The Full Monographs Behind Omega-3 Krill Oil 350 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Krill Oil

Interacts with 208 drugs

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...

Read the full Krill Oil monograph → Herb & supplement monograph

Docosahexaenoic Acid (dha)

Interacts with 375 drugs

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...

Read the full Docosahexaenoic Acid (dha) monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Omega-3 Krill Oil 350 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 65 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Docosahexaenoic Acid (dha) 49 references
  1. Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
  2. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  3. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  4. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  5. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  6. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  7. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  8. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  9. Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
  10. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
  11. Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
  12. Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
  13. Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
  14. Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
  15. Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
  16. Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
  17. Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Supplementation with docosahexaenoic acid in the last trimester of pregnancy: maternal-fetal biochemical findings. J Perinat Med 2004;32:132-6.
  18. Montgomery C, Speake BK, Cameron A, et al. Maternal docosahexaenoic acid supplementation and fetal accretion. Br J Nutr 2003;90:135-45. DOI
  19. Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Pediatr Res 2005;58:235-42. PubMed
  20. Hawkes JS, Bryan DL, Makrides M, et al. A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha. Am J Clin Nutr 2002;75:75
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See these in context on the Docosahexaenoic Acid (dha) monograph →

Astaxanthin 3 references
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See these in context on the Astaxanthin monograph →

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