Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

OncoProtect ES Ingredients & Drug Interactions

by Pure TheraPro Rx

OncoProtect ES label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking OncoProtect ES against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

OncoProtect ES is a dietary supplement by Pure TheraPro Rx with 2 active ingredients. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are TrueBroc. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against OncoProtect ES by Pure TheraPro Rx

Ask about any prescription or over-the-counter medication and we check it for interactions with OncoProtect ES by Pure TheraPro Rx — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of OncoProtect ES by Pure TheraPro Rx

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Glucoraphanin” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.

OncoProtect ES contains two active ingredients: glucoraphanin and myrosinase, delivered as broccoli extract (called TrueBroc). Glucoraphanin is a compound naturally found in broccoli; when myrosinase is present, the two work together to form sulforaphane, a substance some research suggests may support cellular health.

The product also contains hypromellose, an inert capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cellular health and immunity support.
  • We looked for evidence on: Bladder cancer, Breast cancer, Colorectal cancer, Gastric cancer, Prostate cancer, cellular defense — and 2 related terms.
  • The strongest evidence on file: Broccoli is rated "Possibly Effective" for Colorectal cancer (Natural Medicines).
  • Also on file: Broccoli is rated "Insufficient Reliable Evidence To Rate" for Bladder cancer, Breast cancer, Gastric cancer, Prostate cancer.

The evidence for broccoli extract in colorectal cancer prevention is possibly effective based on the data we hold. For other cancers—bladder, breast, and gastric—and for fibromyalgia, the evidence is insufficient to rate whether it works.

This means either the research is limited or mixed, so we can't yet say whether the product would help with those conditions.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a food is generally well tolerated in normal amounts. However, concentrated broccoli supplements like this one are less well studied, and the facts recommend avoiding concentrated extracts unless your doctor approves.

Some people report loose stools, diarrhea, stomach pain, or cramping after taking broccoli seed and sprout extracts, especially at higher doses. Allergic contact reactions to broccoli have also been reported.

Regarding pregnancy and lactation, broccoli extract is rated likely safe, so the safety data does not advise against it during pregnancy or nursing. That said, since concentrated supplements are less studied overall, it's wise to talk with your doctor or pharmacist before starting if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking OncoProtect ES, check with your doctor or pharmacist if you take any medications metabolized by CYP2A6 (including some smoking-cessation aids and pain relievers) or CYP1A2 (including some antidepressants and heart medications). Broccoli extract can speed up how quickly your liver clears these drugs, which may reduce their effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

OncoProtect ES may be worth considering if you're interested in colorectal cancer support and your doctor agrees it fits your health plan. However, because broccoli extract can speed up your liver's breakdown of many medications, you need to check your exact medications with your own doctor or pharmacist before starting—this is especially important if you take anything for smoking cessation, heart conditions, depression, or pain.

If you experience loose stools or stomach cramping after starting, let your healthcare provider know.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about OncoProtect ES, straight from the product label.

Brand Pure TheraPro Rx
Barcode (UPC) X000S6LPC9
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 305963
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for OncoProtect ES by Pure TheraPro Rx, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
X000S6LPC9
IngredientAmount% DV
Glucoraphanin100 mg--
Myrosinase2 mg--
TrueBroc769 mg--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsule daily, or as directed by a healthcare practitioner.

Precautions

Warning: Individuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use.

Warning: Individuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use.

Do not use if tamper seal is damaged.

Keep out of reach of children.

Formula

OncoProtect ES "Extra Strength" is advanced formula containing 2 clinically studied cellular-health-supporting botanical extracts. TrueBroc Glucoraphanin, a patented broccoli seed extract, helps your body effectively identify and eliminate dangerous toxins. Active Myrosinase from radish seed extract, is the enzyme that converts Glucoraphanin into Sulforaphane, one of your body's most potent free radical fighters and cell detoxifiers.

Formulation

When taken together in an extra strength dose, each of these botanicals enhances the bioavailability and efficiency of the other resulting in a remarkably powerful cellular-immunity-supporting formula that's been the subject of over 1,700 published studies.

Formulated to Exclude: Fillers, gluten, wheat, soy, corn, yeast, animal or dairy products, shellfish, fish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMO's), artificial preservatives, sweeteners or colors.

V Vegan

Maximum Sulforaphane Production for Optimal Cellular Support

Formulated, tested & packaged in the USA

Storage

Storage: Keep tightly closed in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Certified Good Manufacturing Practice

FDA Statement of Identity

Professional Dietary Supplement

Brand IP Statement(s)

TrueBroc is a trademark of Brassica Protection Products, LLC Produced under US patents 5,725,895; 5,968,505; 5,968,567; 6,177,122; and 6,242,018 licensed from Brassica Protection Products, LLC.

Copyright 2022 Pure Therapro Rx Purity is Priority

General Statements

Please recycle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

OncoProtect ES by Pure TheraPro Rx label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

OncoProtect ES label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in OncoProtect ES by Pure TheraPro Rx

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glucoraphanin

100 mg per serving

Myrosinase

2 mg per serving Form: Radish Seed Extract

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

OncoProtect ES by Pure TheraPro Rx Drug Interactions

Want to check YOUR meds against OncoProtect ES?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

TrueBroc 187

Individual Drug Interactions

The ingredients in OncoProtect ES interact with 187 drugs. Click any drug to see the details.

1 of the 2 ingredients in OncoProtect ES interact with drugs. Each result below shows which ingredient is responsible. TrueBroc

Each ingredient & the kinds of drugs it affects

For each ingredient in OncoProtect ES with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

TrueBroc2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
TrueBroc full monograph & interactions
The maker

Brand information

Manufacturer and brand details for OncoProtect ES, from the product label.

Pure TheraPro Rx

See all Pure TheraPro Rx products
Name
Pure TheraPro Rx
Street Address
8781 Sheridan Blvd #6080
City
Westminster
State
CO
ZipCode
80003
Phone Number
888-655-4648
Web Address
Purethera.com
Pharmacist Counseling Corner

OncoProtect ES by Pure TheraPro Rx: Common Questions

Does OncoProtect ES by Pure TheraPro Rx interact with any medications?
Yes. Based on its ingredients, OncoProtect ES has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
OncoProtect ES contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will OncoProtect ES help prevent cancer?
The evidence we hold shows broccoli extract is possibly effective for colorectal cancer. For bladder, breast, and gastric cancers, there isn't enough reliable research yet to know whether it works. Talk with your doctor about whether this product fits into your overall health plan.
Is it safe to take if I'm pregnant or breastfeeding?
Broccoli extract is rated likely safe during pregnancy and lactation based on the data we hold. That said, concentrated supplements are less studied than whole broccoli, so check with your doctor or pharmacist before starting to make sure it's right for you.
What side effects might I notice?
Some people report loose stools, diarrhea, stomach pain, or cramping after taking broccoli seed extracts, especially at higher doses. Allergic skin reactions are rare but possible. If you notice any of these, let your healthcare provider know.
What are glucoraphanin and myrosinase?
Glucoraphanin is a natural compound in broccoli. Myrosinase is an enzyme that helps convert glucoraphanin into sulforaphane, a substance thought to support cellular health. Together, they're why broccoli extract is concentrated in this product.
What is TrueBroc?
TrueBroc is the branded form of broccoli extract used in this product. It contains the glucoraphanin and myrosinase mentioned on the label.
Can I take this with my medications?
Broccoli extract can speed up how your liver breaks down many common medications, which may make them less effective. Run your exact medications through the interaction checker on this page, then talk with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if OncoProtect ES is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

OncoProtect ES label
Go deeper

The Full Monographs Behind OncoProtect ES’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

OncoProtect ES's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team