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Dietary supplement

Optimum Absorption Potassium Glycinate Ingredients & Drug Interactions

by Mason Natural

Capsule Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Optimum Absorption Potassium Glycinate is a dietary supplement by Mason Natural with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Optimum Absorption Potassium Glycinate by Mason Natural

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: potassium. Potassium is an electrolyte your body needs for nerve and muscle function, including heartbeat.

The supplement is made with potassium glycinate, a form designed for absorption. The capsule also contains a few inactive ingredients — cellulose gum, stearate, and silicon dioxide — which are fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Electrolyte and fluid balance, heart and nerve health.
  • We looked for evidence on: Hypokalemia, Muscle function, Cardiac rhythm.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts we hold don't include effectiveness ratings for potassium supplementation, so we can't tell you from our data whether this supplement will raise your potassium level as intended. That said, potassium is an essential nutrient, and supplementation is often prescribed by doctors when blood levels are low — but dosing and need are highly individual.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe, but supplements can push your blood level dangerously high, especially if you have kidney disease or take certain medications. The most common side effects when taken by mouth are stomach upset — abdominal pain, nausea, vomiting, diarrhea, gas, and belching.

In rare cases, very high potassium levels can cause irregular heartbeat, low blood pressure, heart block, or mental confusion. During pregnancy, dietary potassium is fine, but don't use supplements without your doctor's guidance.

The same applies to breastfeeding — check with your doctor first.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check any potassium-sparing diuretics, ACE inhibitors, or angiotensin receptor blockers with your pharmacist — all three carry a moderate risk of pushing potassium dangerously high when combined with a supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is for people whose doctor has identified a genuine potassium shortage and approved supplementation. If you take blood pressure or heart medications — especially diuretics, ACE inhibitors, or ARBs — you absolutely must check with your pharmacist or doctor before starting.

Kidney disease is another reason to get professional input first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Optimum Absorption Potassium Glycinate, straight from the product label.

Brand Mason Natural
Barcode (UPC) 311845187499
Net contents 90 Veggie Cap(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336421
Product type Mineral
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Optimum Absorption Potassium Glycinate by Mason Natural, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
311845187499
IngredientAmount% DV
Potassium99 mg2%

Other ingredients: Cellulose Gum, Modified, Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Mason guarantee Laboratory Tested cGMP Certified Good Manufacturing Practice Certified 5 stars

General Statements

N

Please recycle

Brand IP Statement(s)

Mason naturals est. 1967

Mason Natural is a registered trademark and does not refer to any product or ingredient claim.

Formulation

Electrolyte & Fluid balance Heart, nerve & muscle health

Guaranteed no added: Milk, Egg, Peanuts, Tree Nuts, Shellfish, Fish, Soy, Sesame, Wheat.

Soy free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults - Take one capsule daily, preferably with food, as a dietary supplement.

FDA Disclaimer Statement

These statements has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: If you are pregnant, nursing, taking any medications or have any medical condition, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur. Tamper-evident seal: Do not use product if seal appears tampered with.

Keep out of reach of children.

Storage

Store in a dry place under controlled room temperature: 20 degrees –25 degrees C (68 degrees –77 degrees F).

See for yourself

Optimum Absorption Potassium Glycinate by Mason Natural label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Optimum Absorption Potassium Glycinate by Mason Natural

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Potassium

Interacts with
62 drugs
99 mg per serving Form: Potassium Glycinate

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Cellulose Gum, Modified, Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Optimum Absorption Potassium Glycinate by Mason Natural Drug Interactions

Want to check YOUR meds against Optimum Absorption Potassium Glycinate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Optimum Absorption Potassium Glycinate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Optimum Absorption Potassium Glycinate, from the product label.

Mason Natural

See all Mason Natural products
Name
Mason Vitamins, Inc.
City
Miami Lakes
State
FL
ZipCode
33014
Phone Number
1-888-860-5376
Web Address
www.MasonVitamins.com
Pharmacist Counseling Corner

Optimum Absorption Potassium Glycinate by Mason Natural: Common Questions

Does Optimum Absorption Potassium Glycinate by Mason Natural interact with any medications?
Yes. Based on its ingredients, Optimum Absorption Potassium Glycinate has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Optimum Absorption Potassium Glycinate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is potassium glycinate, and why is it in this product?
Potassium glycinate is a form of potassium — an electrolyte your body needs for nerve and muscle function, including a healthy heartbeat. The product is designed to supply potassium when your level is low, but only under medical guidance.
Can I take this if I have kidney disease?
No — the facts advise caution because supplements can push blood potassium dangerously high in people with kidney disease. Talk to your doctor or pharmacist before starting.
Is it safe to take during pregnancy?
Dietary potassium is appropriate during pregnancy, but supplements should only be used under medical guidance. Check with your doctor before taking this.
What are the side effects?
Most commonly, you might feel stomach upset — abdominal pain, nausea, vomiting, diarrhea, gas, or belching. Rarely, very high potassium levels can cause irregular heartbeat, low blood pressure, or confusion. That's why your doctor needs to monitor you.
Can I take this with my blood pressure medication?
It depends on which one. Certain blood pressure drugs — especially potassium-sparing diuretics, ACE inhibitors, and ARBs — interact with potassium supplements and raise the risk of dangerously high blood potassium. Use the medication checker on this page with your exact drug names.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Optimum Absorption Potassium Glycinate is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Optimum Absorption Potassium Glycinate label
Go deeper

The Full Monographs Behind Optimum Absorption Potassium Glycinate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Optimum Absorption Potassium Glycinate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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